[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650670":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":63,"collaborators":25,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":25,"eligibilityCriteria":70,"healthyVolunteers":67,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Postgraduate Institute of Dental Sciences Rohtak","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Partial pulpotomy using calcium hypochlorite as wound lavage agent","EXPERIMENTAL","Partial pulpotomy will be performed using calcium hypochlorite as wound lavage agent ,after establishing a clinical diagnosis of symptomatic irreversible pulpitis i.e. if the tooth showed symptoms triggered and lingered by cold stimuli.",[13],"Procedure: Partial pulpotomy using calcium hypochlorite as wound lavage agent",{"label":15,"type":16,"description":17,"interventionNames":18},"Partial pulpotomy using sodium hypochlorite as wound lavage agent","ACTIVE_COMPARATOR","Partial pulpotomy will be performed using sodium hypochlorite as wound lavage agent ,after establishing a clinical diagnosis of symptomatic irreversible pulpitis i.e. if the tooth showed symptoms triggered and lingered by cold stimuli.",[19],"Procedure: Partial pulpotomy using sodium hypochlorite as wound lavage agent",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Following pulp exposure and clinical assessment of pulp health through bleeding, the patient was randomly assigned to 2.5% Ca(OCl)₂ group.Patients who did not exhibit pulp exposure after complete caries removal, or those with partially necrotic pulp, were excluded from the study.\n\nThe pulp wound was irrigated with 5 ml 2.5% Ca(OCl)₂ for 30 s. Haemostasis was achieved by placing the cotton pellets soaked with 2.5% Ca(OCl)₂ over the pulpal wound for 2 min. This process was repeated further if required, for a maximum of 10 min. Patients whose bleeding could not be arrested within 10 min had to undergo CP or pulpectomy. ProRoot MTA will be placed to a thickness of 2-3 mm gently over the pulpal tissue, a layer of RMGIC will be placed over the MTA.Then the tooth will be permanently restored with composite resin. After restoration, a postoperative periapical radiograph will be taken using a digital imaging system for comparative evaluation after 6 months and 12 months follow up.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Following pulp exposure and clinical assessment of pulp health through bleeding, the patient was randomly assigned to 2.5% NaOCl group.Patients who did not exhibit pulp exposure after complete caries removal, or those with partially necrotic pulp, were excluded from the study.\n\nThe pulp wound was irrigated with 5 ml 2.5% NaOCl for 30 s. Haemostasis was achieved by placing the cotton pellets soaked with 2.5% NaOCl over the pulpal wound for 2 min. This process was repeated further if required, for a maximum of 10 min. Patients whose bleeding could not be arrested within 10 min had to undergo CP or pulpectomy. ProRoot MTA will be placed to a thickness of 2-3 mm gently over the pulpal tissue, a layer of RMGIC will be placed over the MTA.Then the tooth will be permanently restored with composite resin. After restoration, a postoperative periapical radiograph will be taken using a digital imaging system for comparative evaluation after 6 months and 12 months follow up.",[15],[30],{"name":31,"affiliation":32,"role":33},"Dr Mayank Arora, MDS","PGIDS, Rohtak, 124001","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Dr. Mayank Arora, MDS","CONTACT","+918295964200","dr.arora002@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Dr. Roshni N V, PG student","+919048217877","roshninv1997@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"PGIDS","RECRUITING","Rohtak","Haryana","124001","India","IN",{"type":54,"coordinates":55},"Point",[56,57],76.58917,28.89447,{"lat":57,"lon":56},[60,61],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},{"name":62,"role":37,"phone":42,"phoneExt":25,"email":43},"Dr. Roshni N V, MDS",{"type":64,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100650670","outcome-of-partial-pulpotomy-in-permanent-mandibular-molars-with-symptomatic-irreversible-pulpitis-after-wound-lavage-with-calcium-hypochlorite-or-sodium-hypochlorite-100650670",false,"NCT07748676","Outcome of Partial Pulpotomy in Permanent Mandibular Molars With Symptomatic Irreversible Pulpitis After Wound Lavage With Calcium Hypochlorite or Sodium Hypochlorite","Inclusion Criteria:\n\n1. patients aged 18-40 years\n2. Mature permanent mandibular molars with extremely deep caries (caries penetrating the entire thickness of the dentine radiographically, without radiopaque zone separating lesion from the pulp) and clinical diagnosis of SIP with PAI score ≤ 2\n3. Periodontally healthy teeth (probing pocket depth ≤3 mm and mobility within normal limit)\n4. Patients having physical status of class 1 or 2 according to ASA classification\n5. Pulpal bleeding could be controlled within 10 min following pulp amputation\n\nExclusion Criteria:\n\n1. Non restorable teeth\n2. No pulp exposure even after complete caries excavation\n3. Necrotic or partially necrotic pulp upon exposure\n4. Presence of sinus tract or soft tissue swelling\n5. Radiographic signs of internal or external root resorption\n6. Pregnant women","ALL","18 Years","40 Years",{"count":75,"type":76},106,"ESTIMATED","INTERVENTIONAL",[79],"NA","The aim of this randomised control trial is to compare the effect of wound lavage using 2.5% Ca(OCl)₂ and 2.5% NaOCl on the outcome of partial pulpotomy in mature permanent mandibular molars with symptomatic irreversible pulpitis (SIP).Primary objective is to evaluate and compare clinical and radiographic outcome of partial pulpotomy following use of 2.5% Ca(OCl)₂ and 2.5% NaOCl in mature permanent mandibular molars with symptomatic irreversible pulpitis.secondary objective is to evaluate OHRQoL and pain experience after use of 2.5% Ca(OCl)₂ and 2.5% NaOCl during partial pulpotomy in permanent mandibular molars with clinical signs indicative of symptomatic irreversible pulpitis.",[82,83],"Symptomatic Irreversible Pulpitis (SIP)","Extremely Deep Caries",[85],"partial pulpotomy","2026-07-31",{"date":88,"type":89},"2026-08-06","ACTUAL",{"date":91,"type":89},"2026-04-29",{"date":93,"type":76},"2027-10-28",{"name":5,"class":6},1]