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Evidence indicates that ICU hospitalization is associated with a poorer prognosis regarding mental health and morbi-mortality compared to hospitalization in conventional wards.\n\nDespite this recognized vulnerability, available data remain limited and are often derived from retrospective studies with conflicting results. Some studies have shown that SMIs impact neither critical care nor long-term mortality. Conversely, other research has reported higher hospital mortality, an increase in complications (such as mechanical ventilation and prolonged length of stay), and unfavorable functional outcomes. Regarding specific conditions like septic shock, unexpected findings have been observed, with certain SMIs appearing to be associated with reduced 90-day mortality compared to a matched control population.\n\nPatients with SMIs thus represent a vulnerable population whose management in the ICU setting may pose specific challenges. This prospective, multicenter study aims to evaluate mortality and identify predictive factors of mortality among patients with SMIs managed in French ICUs.",[439,440],"Severe Mental Illness","Severe Mental Disorder",[442,443,444,445,446,447,448],"Severe mental illness","Intensive care unit","Patient outcome","Mortality","Frailty","ICU readmission","Severe mental disorder","NOT_YET_RECRUITING","2026-07-15",{"date":452,"type":453},"2026-07-16","ACTUAL",{"date":455,"type":435},"2026-09",{"date":457,"type":435},"2031-09",{"name":5,"class":6},30]