[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646805":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":32,"locations":38,"responsibleParty":56,"collaborators":36,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":36,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":36,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":82,"overallStatus":41,"whyStopped":36,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Benha University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Endometriotic Cyst Group","EXPERIMENTAL","Patients with endometriotic ovarian cysts (endometriomas) diagnosed by transvaginal ultrasound or MRI, confirmed by histopathological examination postoperatively. Participants will undergo laparoscopic ovarian cystectomy under general anesthesia. The procedure involves excision of the cyst wall from adjacent ovarian tissue using traction with grasping forceps, hemostasis achieved via electrocoagulation or sutures, and plication of ovarian incision edges. Any visible endometriotic lesions within the pelvic cavity will be excised or cauterized as appropriate. All patients will be followed up at 3 months postoperatively with serum AMH, FSH, and transvaginal ultrasound for AFC assessment.",[13],"Procedure: Laparoscopic Ovarian Cystectomy",{"label":15,"type":16,"description":17,"interventionNames":18},"Non-Endometriotic Cyst Group","ACTIVE_COMPARATOR","Patients with non-endometriotic benign ovarian cysts (including dermoid cysts, serous cystadenomas, mucinous cystadenomas, and other benign cysts) diagnosed by transvaginal ultrasound or MRI, confirmed by histopathological examination postoperatively. Participants will undergo laparoscopic ovarian cystectomy under general anesthesia. The procedure involves excision of the cyst wall from adjacent ovarian tissue using traction with grasping forceps, hemostasis achieved via electrocoagulation or sutures, and plication of ovarian incision edges. All patients will be followed up at 3 months postoperatively with serum AMH, FSH, and transvaginal ultrasound for AFC assessment.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Laparoscopic Ovarian Cystectomy","Laparoscopic excision of ovarian cyst under general anesthesia. The procedure includes: (1) CO₂ pneumoperitoneum creation via Veress needle through a 1-cm umbilical incision until intraabdominal pressure reaches 15 mmHg; (2) insertion of a 10-mm umbilical trocar and telescope; (3) placement of two or more 5-mm ancillary trocars under direct visualization; (4) incision of the ovarian capsule using monopolar scissors; (5) identification and careful dissection of the cyst wall from adjacent ovarian tissue using traction with grasping forceps; (6) hemostasis achieved using electrocoagulation or sutures; (7) plication and approximation of the ovarian incision edges; (8) for endometriosis cases, excision or cauterization of visible endometriotic lesions; (9) histopathological examination of the excised specimen to confirm diagnosis. The procedure is performed in both arms (endometriotic and non-endometriotic cysts) using identical surgical techniques.",[9,15],[26],"Laparoscopic cystectomy; ovarian cyst removal; laparoscopic ovarian conservation surgery",[28],{"name":29,"affiliation":30,"role":31},"AHMED ALNEZAMY, MD","Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Benha University","PRINCIPAL_INVESTIGATOR",[33],{"name":29,"role":34,"phone":35,"phoneExt":36,"email":37},"CONTACT","01224849065",null,"AHMED.ALNZAMY@fmed.bu.edu.eg",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Benha Univesity Hospital","RECRUITING","Banhā","Qalyubia Governorate","13512","Egypt","EG",{"type":48,"coordinates":49},"Point",[50,51],31.1842,30.45977,{"lat":51,"lon":50},[54],{"name":29,"role":34,"phone":55,"phoneExt":36,"email":37},"00201224849065",{"type":31,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"Ahmed Abdel Latif Ahmed Alnezamy","Principal Investigator and Lecturer of Obstetrics and Gynecology, Faculty of Medicine","100646805","ovarian-reserve-after-laparoscopic-cystectomy-for-endometriotic-and-non-endometriotic-cysts-100646805",false,"NCT07686783","Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts","Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts: A Comparative Prospective Cohort Study","Inclusion Criteria:\n\n* Female patients aged 18-45 years\n* Ovarian cyst measuring 6-15 cm in diameter, confirmed by transvaginal ultrasound or MRI\n* Cyst is persistent for more than 3 months if asymptomatic, OR any symptomatic cyst regardless of duration of diagnosis\n* Serum anti-Müllerian hormone (AMH) level ≥ 2 ng\u002FmL, measured within 1 month preoperatively\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Clinical or ultrasonic suspicion of ovarian malignancy\n* Ovarian cyst associated with pregnancy\n* Previous history of ovarian surgery\n* History of pelvic irradiation or chemotherapy\n* Known endocrine disorders affecting ovarian function (e.g., PCOS, premature ovarian insufficiency, thyroid dysfunction, hyperprolactinemia)\n* Current use of hormonal contraceptives or hormonal therapy within 3 months prior to enrollment\n* Presence of severe systemic disease that contraindicates surgery or general anesthesia\n* Refusal to participate or inability to provide informed consent","FEMALE","18 Years","45 Years",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","We will conduct this study to estimate the effect of laparoscopic cystectomy on ovarian reserve in endometriotic cysts versus non-endometriotic cysts.",[77,78,79,80,81],"Ovarian Cysts","Endometriosis","Benign Ovarian Cyst","Ovarian Reserve","Cystectomy",[83,81,84,85,86],"Laparoscopy","Endometriotic Ovarian Cysts","Benign Ovarian Cysts","Ovarian Reserve Markers","2026-07-02",{"date":89,"type":90},"2026-07-07","ACTUAL",{"date":92,"type":71},"2026-06-30",{"date":94,"type":71},"2027-09",{"name":5,"class":6},1]