[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100436960":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":16,"studyPopulation":17,"armGroups":18,"interventions":13,"overallOfficials":49,"centralContacts":54,"locations":63,"responsibleParty":1006,"collaborators":13,"id":1008,"slug":1009,"hasResults":1010,"nctId":1011,"briefTitle":1012,"officialTitle":1012,"acronym":1013,"eligibilityCriteria":1014,"healthyVolunteers":1015,"sex":1016,"minAge":1017,"maxAge":1018,"enrollmentInfo":1019,"targetDuration":13,"studyType":1022,"phases":13,"briefSummary":1023,"conditions":1024,"keywords":13,"overallStatus":87,"whyStopped":13,"lastUpdateSubmitDate":1029,"lastUpdatePostDateStruct":1030,"startDateStruct":1033,"completionDateStruct":1035,"leadSponsor":1037,"locationsCount":1038},{"fullName":5,"class":6},"Arbor Research Collaborative for Health","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Development of PDAC","Diagnosis of PDAC","Through study completion, an average of 6 years",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":6,"maskingInfo":13},"COHORT","The main objective of the PRECEDE Consortium is to build a shared resource to drive research in critical areas necessary for early detection and prevention of PDAC.\n\nThe PRECEDE Consortium is an observational prospective cohort study, with single or serial biosample collection (every 6-12 months) in defined high-risk groups.\n\nA standardized procedure for collection and processing of human blood for the PRECEDE Consortium will be applied to all blood samples collected as part of the study. Barcoded samples will be stored at the clinical centers, using the specific labels for the PRECEDE study and corresponding data will be entered into the study database.\n\nClinical data and outcomes will be obtained from institutional databases or clinical records to correlate patient information with laboratory results from biospecimens obtained for research. Patients will be followed by their attending physician and receive the standard follow-up care after the procedure in which biospecimen was obtained. It is the intent that biospecimens will be made available to all consortium investigators.","The study will accrue subjects who present for risk assessment at one of the participating sites based on history of:\n\n* one or more family members with PDAC\n* a pathogenic or likely pathogenic germline variant in a gene linked to PDAC risk\n* personal history of PDAC with PGV in genes of research interest and\u002For part of a Familial Pancreatic Cancer kindred",[19,22,25,28,31,34,37,40,43,46],{"label":20,"type":13,"description":21,"interventionNames":13},"Cohort 1","Individuals without history of PDAC meeting any of the following criteria:\n\n1. 2+ relatives with PDAC on same side of family where 2 affected are first degree related to each other and at least 1 affected is first degree related to subject; age 50+ or ≤10 years younger than earliest PDAC in family at time of diagnosis.\n2. 2 affected first degree relatives with PDAC; age 50+ or 10 years younger than earliest PDAC in family\n3. BRCA1, BRCA2, PALB2, ATM, MLH1, MSH2, MSH6, PMS2, EPCAM pathogenic or likely pathogenic variant AND 1 first or second degree relative with PDAC; age 50+ or 10 years younger than earliest PDAC in family\n4. Familial Atypical Moles and Malignant Melanoma (FAMMM) with pathogenic or likely pathogenic CDKN2A variant; age 40+\n5. Peutz-Jegher syndrome with STK11 pathogenic or likely pathogenic variant; age 35+\n6. Hereditary pancreatitis with PRSS1 pathogenic or likely pathogenic variant and history of pancreatitis; age 40+",{"label":23,"type":13,"description":24,"interventionNames":13},"Cohort 2","Individuals without history of PDAC meeting any of the following criteria:\n\n1. ATM, BRCA1, BRCA2, or PALB2 pathogenic or likely pathogenic variant regardless of family history, age 50+\n2. 2+ relatives with PDAC on the same side of family, any degree of relation, not meeting other criteria above; age 50+ or 10 years younger than earliest PDAC in family\n3. 1 FDR with PDAC ≤ age 45; age up to 10 years younger than PDAC diagnosis in family member",{"label":26,"type":13,"description":27,"interventionNames":13},"Cohort 3","Individual meeting criteria for Cohorts 1 or 2 EXCEPT age (i.e. too young to qualify for Cohorts 1 or 2)",{"label":29,"type":13,"description":30,"interventionNames":13},"Cohort 4","Individuals without history of PDAC presenting for evaluation who do not meet any criteria for 1-3, 6, or the Cyst Cohort.",{"label":32,"type":13,"description":33,"interventionNames":13},"Cohort 5","Individuals without history of PDAC who are not otherwise engaged in pancreas surveillance at a participating site may be invited to participate in the PRECEDE database and to donate a biosample (e.g. blood, saliva, and\u002For buccal swab) for discovery studies. This may include relatives of individuals in Cohorts 1-4,6, and the Cyst Cohort.",{"label":35,"type":13,"description":36,"interventionNames":13},"Cyst Cohort","Individuals with a personal history of a pancreatic cystic neoplasm not meeting any criteria for Cohorts 1-3 or 6 (no known family history of PDAC, no known pathogenic germline variants linked to PDAC risk)",{"label":38,"type":13,"description":39,"interventionNames":13},"Cohort 6a","Individuals diagnosed with PDAC or pancreatic high-grade dysplasia after enrollment in PRECEDE meeting any of the following criteria:\n\n1. Family history includes at least one first degree relative with PDAC, or 2 relatives with PDAC who are first degree related to each other\n2. Personal or family history of a pathogenic or likely pathogenic germline variant in ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2,PMS2, PRSS1, STK11",{"label":41,"type":13,"description":42,"interventionNames":13},"Cohort 6b","Individuals with a personal history of PDAC or pancreatic high-grade dysplasia meeting any of the following criteria:\n\n1. Family history includes at least one first degree relative with PDAC, or 2 relatives with PDAC who are first degree related to each other\n2. Personal or family history of a pathogenic or likely pathogenic germline variant in ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2,PMS2, PRSS1, STK11\n3. Diagnosed ≤ age 45",{"label":44,"type":13,"description":45,"interventionNames":13},"Cohort 6c","Individuals with newly diagnosed early stage (stage I or stage II) PDAC seen at a PRECEDE site that do not meet the criteria for 6a or 6b.",{"label":47,"type":13,"description":48,"interventionNames":13},"Cohort 6d","Individuals with PDAC seen at a PRECEDE site that do not meet the criteria for 6a, 6b, or 6c.",[50],{"name":51,"affiliation":52,"role":53},"Diane Simeone, MD","UC San Diego Moores Cancer Center","STUDY_CHAIR",[55,60],{"name":56,"role":57,"phone":58,"phoneExt":13,"email":59},"Naveen Fawas, BS","CONTACT","7346654108","naveen.fawaz@arborresearch.org",{"name":61,"role":57,"phone":58,"phoneExt":13,"email":62},"John Graff, PhD","john.graff@arborresearch.org",[64,85,101,117,134,147,162,174,192,207,222,237,253,269,286,302,318,334,349,364,380,396,411,432,447,463,479,494,509,521,538,553,570,590,606,618,633,649,660,670,686,695,713,728,743,759,776,793,808,823,839,855,875,893,912,930,945,958,976,990],{"facility":65,"status":66,"city":67,"state":68,"zip":69,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":77,"contacts":78},"Mayo Clinic Arizona","NOT_YET_RECRUITING","Phoenix","Arizona","85054","United States","US",{"type":73,"coordinates":74},"Point",[75,76],-112.07404,33.44838,{"lat":76,"lon":75},[79,82],{"name":80,"role":57,"phone":13,"phoneExt":13,"email":81},"Michele Richardson","richardson.michele@mayo.edu",{"name":83,"role":84,"phone":13,"phoneExt":13,"email":13},"Michelle Anderson","PRINCIPAL_INVESTIGATOR",{"facility":86,"status":87,"city":88,"state":68,"zip":89,"country":70,"countryCode":71,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Honor Health Research Institute","RECRUITING","Scottsdale","85258",{"type":73,"coordinates":91},[92,93],-111.89903,33.50921,{"lat":93,"lon":92},[96,99],{"name":97,"role":57,"phone":13,"phoneExt":13,"email":98},"Jeanette Dupree","jdupree@honorhealth.com",{"name":100,"role":84,"phone":13,"phoneExt":13,"email":13},"Erkut Borazanci, MD",{"facility":102,"status":87,"city":103,"state":104,"zip":105,"country":70,"countryCode":71,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"Providence Health and Services","Burbank","California","91505",{"type":73,"coordinates":107},[108,109],-118.30897,34.18084,{"lat":109,"lon":108},[112,115],{"name":113,"role":57,"phone":13,"phoneExt":13,"email":114},"Taridu Ekanayake","emtaridu.ekanayake@providence.org",{"name":116,"role":84,"phone":13,"phoneExt":13,"email":13},"Ora Gordon, MD, MS. FACMG",{"facility":118,"status":87,"city":119,"state":104,"zip":120,"country":70,"countryCode":71,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"City of Hope","Duarte","91010",{"type":73,"coordinates":122},[123,124],-117.97729,34.13945,{"lat":124,"lon":123},[127,130,132],{"name":128,"role":57,"phone":13,"phoneExt":13,"email":129},"Diamond Ward","diward@coh.org",{"name":131,"role":84,"phone":13,"phoneExt":13,"email":13},"James Lin",{"name":133,"role":84,"phone":13,"phoneExt":13,"email":13},"Greg Idos",{"facility":52,"status":87,"city":135,"state":104,"zip":136,"country":70,"countryCode":71,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"La Jolla","92093",{"type":73,"coordinates":138},[139,140],-117.2742,32.84727,{"lat":140,"lon":139},[143,146],{"name":144,"role":57,"phone":13,"phoneExt":13,"email":145},"Emma Vail","e2brooks@health.ucsd.edu",{"name":51,"role":84,"phone":13,"phoneExt":13,"email":13},{"facility":148,"status":87,"city":149,"state":104,"zip":150,"country":70,"countryCode":71,"cosmosGeoPoint":151,"geoPoint":155,"contacts":156},"Cedars-Sinai Medical Center","Los Angeles","90048",{"type":73,"coordinates":152},[153,154],-118.24368,34.05223,{"lat":154,"lon":153},[157,160],{"name":158,"role":57,"phone":13,"phoneExt":13,"email":159},"Jenny Frisendahl","jenny.frisendahl@cshs.org",{"name":161,"role":84,"phone":13,"phoneExt":13,"email":13},"Srinivas Gaddam",{"facility":163,"status":87,"city":149,"state":104,"zip":164,"country":70,"countryCode":71,"cosmosGeoPoint":165,"geoPoint":167,"contacts":168},"UCLA Health","90095",{"type":73,"coordinates":166},[153,154],{"lat":154,"lon":153},[169,172],{"name":170,"role":57,"phone":13,"phoneExt":13,"email":171},"Sophia Quiroz","SStokes@mednet.ucla.edu",{"name":173,"role":84,"phone":13,"phoneExt":13,"email":13},"Timothy Donahue, MD",{"facility":175,"status":87,"city":176,"state":104,"zip":177,"country":70,"countryCode":71,"cosmosGeoPoint":178,"geoPoint":182,"contacts":183},"Hoag","Newport Beach","92663",{"type":73,"coordinates":179},[180,181],-117.92895,33.61891,{"lat":181,"lon":180},[184,187,190],{"name":185,"role":57,"phone":13,"phoneExt":13,"email":186},"Alexandria Adams","alexandria.adams@hoag.org",{"name":188,"role":57,"phone":13,"phoneExt":13,"email":189},"Zulma Loera","zulma.loera@hoag.org",{"name":191,"role":84,"phone":13,"phoneExt":13,"email":13},"Michael Demeure, MD",{"facility":193,"status":87,"city":194,"state":104,"zip":195,"country":70,"countryCode":71,"cosmosGeoPoint":196,"geoPoint":200,"contacts":201},"UC Irvine Health","Orange","92868",{"type":73,"coordinates":197},[198,199],-117.85311,33.78779,{"lat":199,"lon":198},[202,205],{"name":203,"role":57,"phone":13,"phoneExt":13,"email":204},"Blake Johnson","blakej@hs.uci.edu",{"name":206,"role":84,"phone":13,"phoneExt":13,"email":13},"Jennifer Valerin, MD, PhD",{"facility":208,"status":87,"city":209,"state":104,"zip":210,"country":70,"countryCode":71,"cosmosGeoPoint":211,"geoPoint":215,"contacts":216},"UC Davis","Sacramento","95817",{"type":73,"coordinates":212},[213,214],-121.4944,38.58157,{"lat":214,"lon":213},[217,220],{"name":218,"role":57,"phone":13,"phoneExt":13,"email":219},"Tanpreet Dodd","tkdodd@health.ucdavis.edu",{"name":221,"role":84,"phone":13,"phoneExt":13,"email":13},"Edward Kim, MD, PhD",{"facility":223,"status":87,"city":224,"state":104,"zip":225,"country":70,"countryCode":71,"cosmosGeoPoint":226,"geoPoint":230,"contacts":231},"University of California, San Francisco (UCSF)","San Francisco","94143",{"type":73,"coordinates":227},[228,229],-122.41942,37.77493,{"lat":229,"lon":228},[232,235],{"name":233,"role":57,"phone":13,"phoneExt":13,"email":234},"Kurt Giles","PancreasCRC@ucsf.edu",{"name":236,"role":84,"phone":13,"phoneExt":13,"email":13},"Margaret Tempero, MD",{"facility":238,"status":87,"city":239,"state":240,"zip":241,"country":70,"countryCode":71,"cosmosGeoPoint":242,"geoPoint":246,"contacts":247},"Yale University","New Haven","Connecticut","06510",{"type":73,"coordinates":243},[244,245],-72.92816,41.30815,{"lat":245,"lon":244},[248,251],{"name":249,"role":57,"phone":13,"phoneExt":13,"email":250},"Scott Merenda","scott.merenda@yale.edu",{"name":252,"role":84,"phone":13,"phoneExt":13,"email":13},"James Farrell",{"facility":254,"status":87,"city":255,"state":256,"zip":257,"country":70,"countryCode":71,"cosmosGeoPoint":258,"geoPoint":262,"contacts":263},"Mayo Clinic Jacksonville","Jacksonville","Florida","32224",{"type":73,"coordinates":259},[260,261],-81.65565,30.33218,{"lat":261,"lon":260},[264,267],{"name":265,"role":57,"phone":13,"phoneExt":13,"email":266},"Christian Glover","glover.christian@mayo.edu",{"name":268,"role":84,"phone":13,"phoneExt":13,"email":13},"Yan Bi",{"facility":270,"status":87,"city":271,"state":256,"zip":272,"country":70,"countryCode":71,"cosmosGeoPoint":273,"geoPoint":277,"contacts":278},"University of Miami","Miami","33136",{"type":73,"coordinates":274},[275,276],-80.19366,25.77427,{"lat":276,"lon":275},[279,282,284],{"name":280,"role":57,"phone":13,"phoneExt":13,"email":281},"Casper Ruiz Ruiz","cxr1353@med.miami.edu",{"name":283,"role":84,"phone":13,"phoneExt":13,"email":13},"Dan Sussman",{"name":285,"role":84,"phone":13,"phoneExt":13,"email":13},"Nipun Merchant",{"facility":287,"status":87,"city":288,"state":256,"zip":289,"country":70,"countryCode":71,"cosmosGeoPoint":290,"geoPoint":294,"contacts":295},"Moffitt Cancer Center","Tampa","33612",{"type":73,"coordinates":291},[292,293],-82.45843,27.94752,{"lat":293,"lon":292},[296,300],{"name":297,"role":57,"phone":298,"phoneExt":13,"email":299},"Toni Basinski","813.745.6360","Toni.Basinski@Moffitt.Org",{"name":301,"role":84,"phone":13,"phoneExt":13,"email":13},"Jenny Permuth",{"facility":303,"status":87,"city":304,"state":305,"zip":306,"country":70,"countryCode":71,"cosmosGeoPoint":307,"geoPoint":311,"contacts":312},"Emory University Hospital","Atlanta","Georgia","30322",{"type":73,"coordinates":308},[309,310],-84.38798,33.749,{"lat":310,"lon":309},[313,316],{"name":314,"role":57,"phone":13,"phoneExt":13,"email":315},"Halley Fowler","halley.fowler@emory.edu",{"name":317,"role":84,"phone":13,"phoneExt":13,"email":13},"Saurabh Chawla, MD, AGAF, FACG, FASGE",{"facility":319,"status":87,"city":320,"state":321,"zip":322,"country":70,"countryCode":71,"cosmosGeoPoint":323,"geoPoint":327,"contacts":328},"Illinois CancerCare","Bloomington","Illinois","61704",{"type":73,"coordinates":324},[325,326],-88.99369,40.4842,{"lat":326,"lon":325},[329,332],{"name":330,"role":57,"phone":13,"phoneExt":13,"email":331},"Carrie Geoffroy","cgeoffroy@illinoiscancercare.com",{"name":333,"role":84,"phone":13,"phoneExt":13,"email":13},"Kimberly Ku, 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MD",{"facility":365,"status":87,"city":366,"state":367,"zip":368,"country":70,"countryCode":71,"cosmosGeoPoint":369,"geoPoint":373,"contacts":374},"University of Kansas Medical Center","Kansas City","Kansas","66160",{"type":73,"coordinates":370},[371,372],-94.62746,39.11417,{"lat":372,"lon":371},[375,378],{"name":376,"role":57,"phone":13,"phoneExt":13,"email":377},"Jodi Claybaugh","jclaybaugh@kumc.edu",{"name":379,"role":84,"phone":13,"phoneExt":13,"email":13},"Ajay Bansal, MD",{"facility":381,"status":87,"city":382,"state":383,"zip":384,"country":70,"countryCode":71,"cosmosGeoPoint":385,"geoPoint":389,"contacts":390},"Massachusetts General Hospital","Boston","Massachusetts","02114",{"type":73,"coordinates":386},[387,388],-71.05977,42.35843,{"lat":388,"lon":387},[391,394],{"name":392,"role":57,"phone":13,"phoneExt":13,"email":393},"Danielle Lynch","dlynch22@mgh.harvard.edu",{"name":395,"role":84,"phone":13,"phoneExt":13,"email":13},"Daniel Chung",{"facility":397,"status":87,"city":398,"state":383,"zip":399,"country":70,"countryCode":71,"cosmosGeoPoint":400,"geoPoint":404,"contacts":405},"Umass Memorial Medical Center","Worcester","01655",{"type":73,"coordinates":401},[402,403],-71.80229,42.26259,{"lat":403,"lon":402},[406,409],{"name":407,"role":57,"phone":13,"phoneExt":13,"email":408},"Paige Malone","paige.malone@umassmed.edu",{"name":410,"role":84,"phone":13,"phoneExt":13,"email":13},"James Lindberg, MD",{"facility":412,"status":87,"city":413,"state":414,"zip":415,"country":70,"countryCode":71,"cosmosGeoPoint":416,"geoPoint":420,"contacts":421},"University of Michigan","Ann Arbor","Michigan","48109",{"type":73,"coordinates":417},[418,419],-83.74088,42.27756,{"lat":419,"lon":418},[422,425,428,430],{"name":423,"role":57,"phone":13,"phoneExt":13,"email":424},"Sarah Volk","stomanic@med.umich.edu",{"name":426,"role":57,"phone":13,"phoneExt":13,"email":427},"Erika 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Center","Omaha","Nebraska","68198",{"type":73,"coordinates":453},[454,455],-95.94043,41.25626,{"lat":455,"lon":454},[458,461],{"name":459,"role":57,"phone":13,"phoneExt":13,"email":460},"Suzanne Wessling","suzanne.wessling@unmc.edu",{"name":462,"role":84,"phone":13,"phoneExt":13,"email":13},"Kelsey Klute",{"facility":464,"status":87,"city":465,"state":466,"zip":467,"country":70,"countryCode":71,"cosmosGeoPoint":468,"geoPoint":472,"contacts":473},"Hackensack Meridian Health","Hackensack","New Jersey","07601",{"type":73,"coordinates":469},[470,471],-74.04347,40.88593,{"lat":471,"lon":470},[474,477],{"name":475,"role":57,"phone":13,"phoneExt":13,"email":476},"Christianna Torres","christianna.torres@hmhn.org",{"name":478,"role":84,"phone":13,"phoneExt":13,"email":13},"Rosario Ligresti, MD",{"facility":480,"status":66,"city":481,"state":481,"zip":482,"country":70,"countryCode":71,"cosmosGeoPoint":483,"geoPoint":487,"contacts":488},"Memorial Sloan Kettering Cancer Center","New 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least 1 affected is first degree related to subject; age 50+ or ≤10 years younger than earliest PDAC in family at time of diagnosis.\n2. 2 affected first degree relatives with PDAC; age 50+ or 10 years younger than earliest PDAC in family\n3. BRCA1, BRCA2, PALB2, ATM, MLH1, MSH2, MSH6, PMS2, EPCAM pathogenic or likely pathogenic variant AND 1 first or second degree relative with PDAC; age 50+ or 10 years younger than earliest PDAC in family\n4. Familial Atypical Moles and Malignant Melanoma (FAMMM) with pathogenic or likely pathogenic CDKN2A variant; age 40+\n5. Peutz-Jegher syndrome with STK11 pathogenic or likely pathogenic variant; age 35+\n6. Hereditary pancreatitis with PRSS1 pathogenic or likely pathogenic variant and history of pancreatitis; age 40+\n\nCohort 2\n\nIndividuals without history of PDAC meeting any of the following criteria:\n\n1. ATM, BRCA1, BRCA2, or PALB2 pathogenic or likely pathogenic variant regardless of family history, age 50+\n2. 2+ relatives with PDAC on the same side of family, any degree of relation, not meeting other criteria above; age 50+ or 10 years younger than earliest PDAC in family\n3. 1 first degree relative with PDAC ≤ age 45; age up to 10 years younger than PDAC diagnosis in family member\n\nCohort 3 Individual meeting criteria for Cohorts 1 or 2 EXCEPT age (i.e. too young to qualify for Cohorts 1 or 2)\n\nCohort 4 Individuals without history of PDAC presenting for evaluation who do not meet any criteria for 1-3, 6, or the Cyst Cohort.\n\nCohort 5 Individuals without history of PDAC who are not otherwise engaged in pancreas surveillance at a participating site may be invited to participate in the PRECEDE database and to donate a biosample (e.g. blood, saliva, and\u002For buccal swab) for discovery studies. This may include relatives of individuals in Cohorts 1-4,6, and the Cyst Cohort.\n\nCohort 6a\n\nIndividuals diagnosed with PDAC or pancreatic high-grade dysplasia after enrollment in PRECEDE meeting any of the following criteria:\n\n1. Family history includes at least one first degree relative with PDAC, or 2 relatives with PDAC who are first degree related to each other\n2. Personal or family history of a pathogenic or likely pathogenic germline variant in ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2,PMS2, PRSS1, STK11\n\nCohort 6b\n\nIndividuals with a personal history of PDAC or pancreatic high-grade dysplasia meeting any of the following criteria:\n\n1. Family history includes at least one first degree relative with PDAC, or 2 relatives with PDAC who are first degree related to each other\n2. Personal or family history of a pathogenic or likely pathogenic germline variant in ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2,PMS2, PRSS1, STK11\n3. Diagnosed ≤ age 45\n\nCohort 6c Individuals with newly diagnosed early stage (stage I or stage II) PDAC seen at a PRECEDE site that do not meet the criteria for 6a or 6b.\n\nCohort 6d Individuals with PDAC seen at a PRECEDE site that do not meet the criteria for 6a, 6b, or 6c.\n\nCyst Cohort Individuals with a personal history of a pancreatic cystic neoplasm not meeting any criteria for Cohorts 1-3 or 6 (no known family history of PDAC, no known pathogenic germline variants linked to PDAC risk)\n\nExclusion Criteria:\n\n* Individuals not meeting the criteria above.",true,"ALL","18 Years","90 Years",{"count":1020,"type":1021},20000,"ESTIMATED","OBSERVATIONAL","The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multisite cohort of individuals with family history of PDAC and\u002For individuals carrying pathogenic\u002Flikely pathogenic germline variants (PGVs) in genes linked to PDAC risk for longitudinal follow up.",[1025,1026,1027,1028],"Pancreas Cancer","Pancreas Cyst","Pancreatic Ductal Adenocarcinoma","Genetic Predisposition","2026-07-21",{"date":1031,"type":1032},"2026-07-22","ACTUAL",{"date":1034,"type":1032},"2020-09-18",{"date":1036,"type":1021},"2030-12-31",{"name":5,"class":6},60]