[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654895":3},{"organization":4,"outcomesModule":7,"designInfo":25,"detailedDescription":24,"studyPopulation":24,"armGroups":32,"interventions":44,"overallOfficials":54,"centralContacts":62,"locations":68,"responsibleParty":142,"collaborators":144,"id":146,"slug":147,"hasResults":148,"nctId":149,"briefTitle":150,"officialTitle":151,"acronym":152,"eligibilityCriteria":153,"healthyVolunteers":148,"sex":154,"minAge":155,"maxAge":24,"enrollmentInfo":156,"targetDuration":24,"studyType":159,"phases":160,"briefSummary":162,"conditions":163,"keywords":169,"overallStatus":71,"whyStopped":24,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":186,"completionDateStruct":187,"leadSponsor":189,"locationsCount":190},{"fullName":5,"class":6},"University of Chicago","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":24},[9,13],{"measure":10,"description":11,"timeFrame":12},"Numeric Pain Rating Scale","This survey asks patients to rate their pain on a scale from 0 to 10.","Pre-procedure, 2 weeks, 6 weeks, and 12 weeks post-injection",{"measure":14,"description":15,"timeFrame":12},"Knee Osteoarthritis and Outcome Score-Joint Replacement","This standardized survey asks patients to describe the impact of their knee stiffness and pain on daily tasks.",[17,21],{"measure":18,"description":19,"timeFrame":20},"Institutional Survey on Satisfaction with Injection","This survey asks patients to rate their satisfaction with their corticosteroid injection on a scale from 0 to 10.","2 weeks, 6 weeks, and 12 weeks post-injection",{"measure":22,"description":23,"timeFrame":20},"Patient Global Impression of Change","This survey asks patients to rate their overall health status on a scale from 1 to 7.",null,{"allocation":26,"interventionModel":27,"interventionModelDescription":28,"primaryPurpose":29,"observationalModel":24,"timePerspective":24,"maskingInfo":30},"RANDOMIZED","PARALLEL","The population will be adults with symptomatic, radiographically moderate-to-severe medial compartment knee osteoarthritis who are already undergoing corticosteroid injections as part of routine care on their native knee. They wil be randomized to receive their injection on either the anteromedial or anterolateral knee.","TREATMENT",{"masking":31,"maskingDescription":24,"whoMasked":24},"NONE",[33,39],{"label":34,"type":35,"description":36,"interventionNames":37},"Anterolateral","ACTIVE_COMPARATOR","These patients will receive their corticosteroid injections on their anterolateral knees.",[38],"Procedure: Anterolateral Injection",{"label":40,"type":35,"description":41,"interventionNames":42},"Anteromedial","This group of patients will receive injections on the anteromedial side of their knee.",[43],"Procedure: Anteromedial Injection",[45,50],{"type":46,"name":47,"description":48,"armGroupLabels":49,"otherNames":24},"PROCEDURE","Anteromedial Injection","If randomized to this intervention, patients will receive a corticosteroid injection in the anteromedial side of their knee.",[40],{"type":46,"name":51,"description":52,"armGroupLabels":53,"otherNames":24},"Anterolateral Injection","If randomized to this intervention, patients will receive a corticosteroid injection on the anterolateral side of their knee.",[34],[55,59],{"name":56,"affiliation":57,"role":58},"Sara JS Wallace, M.D.\u002FM.P.H.","The University of Chicago Medical Center","PRINCIPAL_INVESTIGATOR",{"name":60,"affiliation":61,"role":58},"Brandon Pardi, M.D.","AdventHealth",[63],{"name":64,"role":65,"phone":66,"phoneExt":24,"email":67},"Malik J Scott, B.A.","CONTACT","773-834-3531","mjscott1@uchicago.edu",[69,88,104,116,130],{"facility":70,"status":71,"city":72,"state":73,"zip":74,"country":75,"countryCode":76,"cosmosGeoPoint":77,"geoPoint":82,"contacts":83},"Bolingbrook Clinic","RECRUITING","Bolingbrook","Illinois","60440","United States","US",{"type":78,"coordinates":79},"Point",[80,81],-88.0684,41.69864,{"lat":81,"lon":80},[84,87],{"name":60,"role":65,"phone":85,"phoneExt":24,"email":86},"630-759-1248","brandon.pardi.md@adventhealth.com",{"name":60,"role":58,"phone":24,"phoneExt":24,"email":24},{"facility":89,"status":71,"city":90,"state":73,"zip":91,"country":75,"countryCode":76,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"Hyde Park Clinic","Chicago","60637",{"type":78,"coordinates":93},[94,95],-87.65005,41.85003,{"lat":95,"lon":94},[98,101,103],{"name":99,"role":65,"phone":66,"phoneExt":24,"email":100},"Sara J Wallace, M.D.\u002FM.P.H.","swallace2@bsd.uchicago.edu",{"name":102,"role":65,"phone":24,"phoneExt":24,"email":67},"Malik Scott, B.A.",{"name":56,"role":58,"phone":24,"phoneExt":24,"email":24},{"facility":105,"status":71,"city":106,"state":73,"zip":107,"country":75,"countryCode":76,"cosmosGeoPoint":108,"geoPoint":112,"contacts":113},"La Grange Clinic","La Grange","60525",{"type":78,"coordinates":109},[110,111],-87.86923,41.80503,{"lat":111,"lon":110},[114,115],{"name":56,"role":65,"phone":66,"phoneExt":24,"email":100},{"name":56,"role":58,"phone":24,"phoneExt":24,"email":24},{"facility":117,"status":71,"city":118,"state":73,"zip":119,"country":75,"countryCode":76,"cosmosGeoPoint":120,"geoPoint":124,"contacts":125},"Orland Park Clinic","Orland Park","60462",{"type":78,"coordinates":121},[122,123],-87.85394,41.63031,{"lat":123,"lon":122},[126,128,129],{"name":56,"role":65,"phone":127,"phoneExt":24,"email":100},"888-824-0200",{"name":64,"role":65,"phone":24,"phoneExt":24,"email":67},{"name":56,"role":58,"phone":24,"phoneExt":24,"email":24},{"facility":131,"status":71,"city":132,"state":73,"zip":133,"country":75,"countryCode":76,"cosmosGeoPoint":134,"geoPoint":138,"contacts":139},"Woodridge Clinic","Woodridge","60517",{"type":78,"coordinates":135},[136,137],-88.05034,41.74697,{"lat":137,"lon":136},[140,141],{"name":60,"role":65,"phone":85,"phoneExt":24,"email":86},{"name":60,"role":58,"phone":24,"phoneExt":24,"email":24},{"type":143,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[145],{"name":61,"class":6},"100654895","patient-pain-and-function-in-medial-knee-osteoarthritis-after-anteromedial-vs-anterolateral-intra-articular-corticosteroid-injection-100654895",false,"NCT07804446","Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection","Does Injection Site (Anteromedial vs Anterolateral) Affect Pain Relief After Intra-Articular Corticosteroid Injection in Moderate-to-Severe Medial Knee Osteoarthritis?","Medial OA CSI","Inclusion Criteria:\n\n* Age ≥ 40\n* Clinical diagnosis of knee OA with predominant medial compartment symptoms\n* Radiographic moderate-to-severe medial compartment OA (KL grade 3-4 or equivalent)\n* Agreed to and preparing to receive a CSI of the knee as part of standard care from surgeon, regardless of past injection of the knee\n* Able to provide informed consent\n* Able to complete phone, email, or MyChart follow-ups in English\n\nExclusion Criteria:\n\n* Predominant lateral compartment OA or patellofemoral-only OA\n* Inflammatory arthritis (RA, gout flare, etc.)\n* Suspected or confirmed joint infection or overlying cellulitis\n* Prior knee arthroplasty on the index knee\n* Planned surgery for index knee within 12-week follow-up\n* Inability to complete follow-up assessments\n* Other clinician-determined contraindication to CSI","ALL","40 Years",{"count":157,"type":158},140,"ESTIMATED","INTERVENTIONAL",[161],"NA","The primary purpose of this study is to find out if there is a difference in pain experienced in patients with knee arthritis of the inside of their knee if they get a steroid injection on the inside or outside of their knee. Participants will:\n\n1. Be randomly divided into getting their steroid injection on the inside or outside of their knee.\n2. Answer a pain survey before their injection as well as over the phone 2 weeks, 6 weeks, and 12 weeks after their injection.",[164,165,166,167,168],"Osteoarthitis","Osteoarthritic Knee Pain","Osteoarthritis (OA)","Osteoarthritis (OA) of the Knee","Osteoarthritis in the Knee",[170,171,172,173,174,175,176,177,178,179,180,181],"osteoarthritis","arthritis","corticosteroid","steroid injection","pain","pain control","pain survey","knee","knee arthritis","knee osteoarthritis","knee pain","knee injection","2026-08-31",{"date":184,"type":185},"2026-09-04","ACTUAL",{"date":182,"type":185},{"date":188,"type":158},"2027-05-01",{"name":5,"class":6},5]