[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646053":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":23,"centralContacts":27,"locations":37,"responsibleParty":62,"collaborators":10,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":10,"maxAge":74,"enrollmentInfo":75,"targetDuration":78,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of Medicine and Pharmacy at Ho Chi Minh City","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Vietnamese Pediatric Movement Disorder Cohort",null,"Vietnamese children with clinically confirmed movement disorders of unknown etiology who meet the study eligibility criteria and are enrolled in the VPeMD registry. Participants will undergo standardized clinical data collection and genetic testing using whole-exome sequencing.",[13],"Diagnostic Test: Whole-Exome Sequencing",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Whole-Exome Sequencing","Whole-exome sequencing will be performed on DNA extracted from peripheral blood samples to identify genetic variants associated with pediatric movement disorders. The test is used for genetic analysis and genotype-phenotype correlation in this observational registry and is not assigned as a treatment intervention.",[9],[21,22],"WES","Next-generation sequencing",[24],{"name":25,"affiliation":5,"role":26},"Linh B. Y Nguyen, MD, MSc, PHD Candidate","PRINCIPAL_INVESTIGATOR",[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Bich Y L Nguyen, MD, MSc, PhD Candidate","CONTACT","+84 939077089","nbylinh.ncs25@ump.edu.vn",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Hieu L. T. Nguyen, Assoc Prof, MD, PhD","+84 908393616","ngletrunghieu@ump.edu.vn",[38,54],{"facility":39,"status":40,"city":41,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Children's Hospital 1, Ho Chi Minh City","RECRUITING","Ho Chi Minh City","700000","Vietnam","VN",{"type":46,"coordinates":47},"Point",[48,49],106.62965,10.82302,{"lat":49,"lon":48},[52],{"name":53,"role":30,"phone":31,"phoneExt":10,"email":32},"Linh B.Y Nguyen, MSc, MD, PPHD Candidate",{"facility":55,"status":40,"city":41,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"University Medical Center Ho Chi Minh City",{"type":46,"coordinates":57},[48,49],{"lat":49,"lon":48},[60],{"name":61,"role":30,"phone":35,"phoneExt":10,"email":36},"Hieu L.T. Nguyen, AProf, MD, PhD",{"type":26,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Nguyen Bich Y Linh","MSc, PhD Candidate","100646053","pediatric-movement-disorders-of-unknown-etiology-in-vietnam-vpemd-100646053",false,"NCT07695610","Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD)","Phenotypic and Genotypic Characterization of Pediatric Movement Disorders of Unknown Etiology in Vietnam","VPeMD","Inclusion Criteria:\n\n* Children younger than 18 years old.\n* Patients with clinically confirmed movement disorders based on direct examination and\u002For video review by at least two pediatric neurology specialists.\n* Patients with movement disorders of unknown etiology after appropriate neurological evaluation and exclusion of clear acquired causes.\n* Patients evaluated or treated at University Medical Center Ho Chi Minh City or Children's Hospital 1 during the study period.\n* Patients and\u002For legal guardians who provide written informed consent for study participation and genetic testing.\n\nExclusion Criteria:\n\n* Patients with isolated or transient primary tic disorders.\n* Patients with a confirmed acquired cause of movement disorder.\n* Patients or legal guardians who decline participation or withdraw from the study.\n* Patients with insufficient clinical information or unavailable biological samples for genetic analysis.","ALL","18 Years",{"count":76,"type":77},50,"ESTIMATED","12 Months","OBSERVATIONAL","This observational patient registry aims to describe the clinical phenotypes and genetic findings of Vietnamese children with movement disorders of unknown etiology. Eligible participants are children with clinically confirmed movement disorders after evaluation by pediatric neurology specialists and after exclusion of clear acquired causes.\n\nThe study will collect clinical data, neurological examination findings, available laboratory and imaging results, and video recordings of abnormal movements when consent is provided. Blood samples will be collected for whole-exome sequencing and related genetic analysis. Genetic variants will be classified according to accepted clinical genetics standards and compared with the patients' clinical phenotypes.\n\nThe study is expected to improve understanding of the phenotypic and genotypic spectrum of pediatric movement disorders in Vietnam, support genetic counseling, and evaluate how genetic results may influence diagnosis, follow-up, prognosis, and treatment planning.",[82,83,84],"Movement Disorders in Children","Neuro Developmental Delay","Neurogenetic Disorders",[71,43,86,87],"Whole Exome Sequencing","Pediatric movement disorders","2026-07-08",{"date":90,"type":91},"2026-07-10","ACTUAL",{"date":93,"type":91},"2026-04-17",{"date":95,"type":77},"2029-01-31",{"name":5,"class":6},2]