[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650266":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":54,"id":86,"slug":87,"hasResults":88,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":88,"sex":94,"minAge":95,"maxAge":11,"enrollmentInfo":96,"targetDuration":11,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":112,"whyStopped":11,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Endoscopic ultrasound (EUS)-guided drainage","EXPERIMENTAL",null,[13],"Device: Plastic double pigtail stent",{"label":15,"type":16,"description":11,"interventionNames":17},"Percutaneous catheter drainage","ACTIVE_COMPARATOR",[18],"Device: Percutaneous catheter",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","Plastic double pigtail stent","EUS-guided placement of plastic double pigtail stent in fluid collection.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Percutaneous catheter","Percutaneous catheter with external collection bag is placed in the fluid collection",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Inge de Vries","CONTACT","+31204440613","i.devries@amsterdamumc.nl",[36],{"facility":37,"status":11,"city":38,"state":11,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Amsterdam UMC, location VUmc","Amsterdam","1081 HV","Netherlands","NL",{"type":43,"coordinates":44},"Point",[45,46],4.88969,52.37403,{"lat":46,"lon":45},[49],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Rogier P. Voermans","Principal investigator",[55,57,59,61,63,66,68,70,72,74,76,78,80,82,84],{"name":56,"class":6},"Azienda Ospedaliera Universitaria Integrata Verona",{"name":58,"class":6},"Leiden University Medical Center",{"name":60,"class":6},"Radboud University Medical Center",{"name":62,"class":6},"St. Antonius Hospital",{"name":64,"class":65},"OLVG","NETWORK",{"name":67,"class":6},"University Medical Center Groningen",{"name":69,"class":6},"Maastricht University Medical Center",{"name":71,"class":6},"Medisch Spectrum Twente",{"name":73,"class":6},"Catharina Ziekenhuis Eindhoven",{"name":75,"class":6},"University Hospital Heidelberg",{"name":77,"class":6},"Erasmus Medical Center",{"name":79,"class":6},"IRCCS San Raffaele",{"name":81,"class":6},"Orlando Health, Inc.",{"name":83,"class":6},"Universitaire Ziekenhuizen KU Leuven",{"name":85,"class":6},"University Hospital, Ghent","100650266","percutaneous-versus-eus-guided-drainage-of-symptomatic-fluid-collections-after-left-pancreatectomy-100650266",false,"NCT07743762","Percutaneous Versus EUS-guided Drainage of Symptomatic Fluid Collections After Left Pancreatectomy","Percutaneous Versus EUS-guided Drainage of Symptomatic Fluid Collections After Left Pancreatectomy (PERSEUS-I): an International Randomized Controlled Trial","PERSEUS-I","Inclusion Criteria:\n\n* ≥18 years\n* Symptomatic fluid collection following a left pancreatectomy requiring drainage according to the treatment team. Indications for drainage exists of:\n\n  1. Symptoms of abdominal pain and\u002For persistent nausea.\n  2. Suspected infection\u002F sepsis\n* Drainage of the fluid collection is feasible both endoscopically and percutaneously as per the treating team. NB: Preferably this is also assessed and supported by the expert panel, but this is NOT mandatory given the potential urgent nature of the intervention. The investigators expect that multidisciplinary consultation with both intervening specialties precedes the feasibility assessment.\n* No contraindications for either procedure. If the contraindication can be overcome safely, such as ascites for which prior abdominal drainage is needed, the patient can still be included.\n* No prior drainage attempts of the fluid collection.\n* In case of a previously intraoperatively placed drain, it should have been removed 5 days prior to fluid collection development.\n\nExclusion Criteria:\n\n* \\\u003C18 years\n* The fluid collection is not endoscopically or percutaneously feasible per the expert panel's judgement or the treatment team in acute situations, for example due to collection location too far from the gastrointestinal tract.\n* Prior drainage attempts of the fluid collection.\n* Received an indwelling percutaneous drain intraoperatively. Intraoperatively placed drains are only permitted when at least removed 5 days prior to development of the fluid collection.\n* Permanent incapacitation of research participant, prior to clinical deterioration caused by the pancreatic fluid collection, without expectation of improvement as per the treatment team.\n* Unable to obtain informed consent by either patient or their legal representative.","ALL","18 Years",{"count":97,"type":98},96,"ESTIMATED","INTERVENTIONAL",[101],"NA","Fluid collections are a complication after pancreatic surgery. These fluid collections can be treated with two treatment options. One option is percutaneous drainage, where an external drainage tube is placed in the collection. The second option is endoscopic ultrasound-guided drainage (EUS) with a stent. Both options have similar results in previous clinical studies, but they have not been directly compared in a randomized clinical trial.\n\nThe goal of this clinical trial is to compare percutaneous drainage with EUS-guided drainage. The main questions it aims to answer are:\n\n* Is EUS-guided drainage of symptomatic fluid collections non-inferior to percutaneous catheter drainage in terms of safety?\n* Is EUS-guided drainage superior in terms of 30-day quality of life, compared to percutaneous drainage?\n\nResearchers will compare EUS-guided drainage with percutaneous drainage to see if they are similar in safety outcomes and different in quality-of-life outcomes.\n\nParticipants will:\n\n* Be randomized between percutaneous drainage and EUS-guided drainage.\n* Fill-out surveys and pain score when they start the study, and then after 1 week and 3 months.\n* Fill-out an extra pain score on day 1 and day 3.\n* Receive a phone call from the study team after 1 month, where they will be asked how they are doing. Together with the study team member they fill out the surveys that are taken after 1 month.",[104],"Symptomatic Fluid Collection(s)",[106,107,108,109,110,111],"EUS-guided drainage","Percutaneous drainage","Endoscopic Ultrasound","Pancreas Surgery","Left pancreatectomy","Fluid collection","NOT_YET_RECRUITING","2026-07-29",{"date":115,"type":116},"2026-08-04","ACTUAL",{"date":118,"type":98},"2026-08-01",{"date":120,"type":98},"2030-05-01",{"name":5,"class":6},1]