[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659541":3},{"organization":4,"outcomesModule":7,"designInfo":28,"detailedDescription":31,"studyPopulation":32,"armGroups":33,"interventions":27,"overallOfficials":37,"centralContacts":42,"locations":27,"responsibleParty":48,"collaborators":27,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":27,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":27,"studyType":65,"phases":27,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":75,"whyStopped":27,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":27},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":27},[9],{"measure":10,"description":11,"timeFrame":12},"Mean nerve cross-sectional area","Mean cross-sectional area of selected peripheral nerves measured by high-resolution ultrasound in mm².","Baseline",[14,18,21,24],{"measure":15,"description":16,"timeFrame":17},"Change in nerve cross-sectional area","Mean change in peripheral nerve cross-sectional area in mm² from baseline to 3 months.","At 3 months",{"measure":19,"description":20,"timeFrame":12},"Mean distal motor latency","Mean distal motor latency measured by nerve conduction study in milliseconds.",{"measure":22,"description":23,"timeFrame":12},"Mean compound muscle action potential amplitude","Mean compound muscle action potential amplitude measured by nerve conduction study in millivolts.",{"measure":25,"description":26,"timeFrame":12},"GBS Disability Scale Score","Mean Guillain-Barré Syndrome disability scale score (range 0 to 6, higher scores indicate worse disability).",null,{"allocation":27,"interventionModel":27,"interventionModelDescription":27,"primaryPurpose":27,"observationalModel":29,"timePerspective":30,"maskingInfo":27},"COHORT","PROSPECTIVE","Guillain-Barré syndrome is an acute immune-mediated neuropathy. High-resolution peripheral nerve ultrasound can measure nerve cross-sectional area and detect structural abnormalities.\n\nThis observational study will perform peripheral nerve ultrasound and nerve conduction studies in children aged 1 to 17 years with Guillain-Barré syndrome at baseline and at 3 months.","Children aged 1 to 17 years diagnosed with Guillain-Barré syndrome admitted to or evaluated at Assiut University Children's Hospital.",[34],{"label":35,"type":27,"description":36,"interventionNames":27},"Children with Guillain-Barré Syndrome","Children aged 1 to 17 years with Guillain-Barré syndrome undergoing peripheral nerve ultrasound and nerve conduction studies.",[38],{"name":39,"affiliation":40,"role":41},"Azza A Eltayeb, prof","Pediatrics Department, Assiut University Hospitals","STUDY_CHAIR",[43],{"name":44,"role":45,"phone":46,"phoneExt":27,"email":47},"Ahmed S Ahmed, Resident","CONTACT","+20 12 70363133","as99709@gmail.com",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Ahmed Sultan Ahmed Shetawy","Resident Physician, Department of Pediatrics","100659541","peripheral-nerve-ultrasound-in-children-with-guillain-barr-syndrome-100659541",false,"NCT07866898","Peripheral Nerve Ultrasound in Children With Guillain-Barré Syndrome","Diagnostic Value of Peripheral Nerve Ultrasound in Children With Guillain-Barré Syndrome","Inclusion Criteria:\n\n* \\- Age 1 to 17 years\n* Diagnosis compatible with Guillain-Barré syndrome according to Brighton criteria\n* Written informed consent from parent or legal guardian\n\nExclusion Criteria:\n\n* Previous diagnosis of hereditary peripheral neuropathy\n* Chronic inflammatory demyelinating polyneuropathy or another chronic neuropathy\n* Previous neuromuscular disease affecting nerve conduction or ultrasound measurements\n* Significant peripheral nerve trauma or previous nerve surgery\n* Drug-induced neuropathy\n* Local anatomical abnormalities or marked edema preventing reliable ultrasound assessment","ALL","1 Year","17 Years",{"count":63,"type":64},42,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate peripheral nerve ultrasound findings, particularly nerve cross-sectional area, in children with Guillain-Barré syndrome.",[68],"Guillain-Barre Syndrome",[70,71,72,73,74],"Guillain-Barre syndrome","Peripheral nerve ultrasound","Nerve cross-sectional area","Children","Assiut","NOT_YET_RECRUITING","2026-10-05",{"date":78,"type":79},"2026-10-08","ACTUAL",{"date":81,"type":64},"2026-10-10",{"date":83,"type":64},"2028-02-01",{"name":5,"class":6}]