[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647959":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":32,"locations":41,"responsibleParty":58,"collaborators":18,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":18,"enrollmentInfo":70,"targetDuration":18,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":88,"whyStopped":18,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pharmacist\u002FCardiologist Virtual Team (Intervention)","EXPERIMENTAL","VA medical centers randomized to the active intervention period receive digital consultation from a centralized pharmacist and cardiologist virtual team regarding guideline-directed medical therapy for hospitalized Veterans with heart failure and during the post-discharge period. The intervention includes identification of eligible Veterans, placement of digital consultation notes in the EHR, facilitation of outpatient follow-up, and Veteran education.",[13],"Behavioral: Pharmacist\u002FCardiologist Virtual Team Digital Consultation",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care (Control Period)","NO_INTERVENTION","VA medical centers during their pre-implementation (control) period provide usual care for Veterans hospitalized with heart failure without input from the pharmacist\u002Fcardiologist virtual team. In the stepped-wedge design, all sites eventually cross over to the intervention arm.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Pharmacist\u002FCardiologist Virtual Team Digital Consultation","A centralized pharmacist and cardiologist virtual team (hub) provides protocol-based digital consultation notes to inpatient and outpatient providers(spoke) regarding initiation and intensification of guideline-directed medical therapy (GDMT) for heart failure during hospitalization and the post-discharge transitional care period. Eligible Veterans are identified via VA dashboards and community care claims data. Recommendations cover quadruple therapy (beta blockers, ACEI\u002FARB\u002FARNI, MRA, SGLT2i) and are tailored to individual clinical presentations. The pharmacist arranges outpatient follow-up and delivers medication adherence education.",[9],[26],"PATRIOT-HF intervention; pharmacist-assisted GDMT optimization",[28],{"name":29,"affiliation":30,"role":31},"Paul L Hess, MD MS","Rocky Mountain Regional VA Medical Center, Aurora, CO","PRINCIPAL_INVESTIGATOR",[33,37],{"name":29,"role":34,"phone":35,"phoneExt":18,"email":36},"CONTACT","(720) 857-6889","paul.hess@va.gov",{"name":38,"role":34,"phone":39,"phoneExt":18,"email":40},"Lexus L Ujano-De Motta, BS","(808) 990-3993","lexus.ujano-demotta@va.gov",[42],{"facility":30,"status":18,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Aurora","Colorado","80045-7211","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-104.83192,39.72943,{"lat":52,"lon":51},[55,57],{"name":29,"role":34,"phone":56,"phoneExt":18,"email":36},"720-857-6889",{"name":29,"role":31,"phone":18,"phoneExt":18,"email":18},{"type":59,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100647959","pharmacist-assisted-titration-of-rx-to-implement-optimal-medical-therapy-for-heart-failure-100647959",false,"NCT07714239","Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure","Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure (PATRIOT-HF) (QUE 25-018)","PATRIOT-HF","Inclusion Criteria:\n\n* Admission to a VA medical center or VA-paid community hospital within the preceding 3 months with a primary diagnosis of heart failure\n\n  * The primary study cohort will consist of those admitted to a VA medical center, while the secondary study cohort will consist of patients admitted to VA-paid community hospitals\n* Left ventricular ejection fraction ≤ 40%\n* Not on optimal guideline-directed heart failure medication classes or doses, as assessed in the electronic health record\n* Receiving care within one of the 6 participating VA medical centers\n\nExclusion Criteria:\n\n* Hemodynamic instability\n* Receiving comfort care measures alone or enrolled in hospice","ALL","18 Years",{"count":71,"type":72},585,"ESTIMATED","INTERVENTIONAL",[75],"NA","Many Veterans who are hospitalized with heart failure do not receive all the recommended heart medications at the right doses before they leave the hospital or in the weeks following discharge. This study tests whether a team of clinical pharmacists and cardiologists, working virtually, can improve heart failure medication prescribing for Veterans at VA medical centers. The pharmacist and cardiologist team reviews patient records and provides recommendations to the treating doctors and primary care providers caring for Veterans with heart failure. The goal is to increase use of guideline-recommended medications, which have been shown to improve survival, reduce hospitalizations, and improve quality of life.",[78,79],"Heart Failure","Heart Failure, Systolic",[81,82,83,84,85,86,87],"Guideline-Directed Medical Therapy","Pharmacists","Medication Therapy Management","Quality Improvement","Veterans Health","Telemedicine","Implementation Science","NOT_YET_RECRUITING","2026-07-15",{"date":91,"type":92},"2026-07-20","ACTUAL",{"date":94,"type":72},"2026-07-24",{"date":96,"type":72},"2030-09-30",{"name":5,"class":6},1]