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m2\n\nExclusion\n\n* Concomitant rheumatological autoimmune disease\n* Considered at high risk for thrombosis\n* Rapidly progressive glomerulonephritis and\u002For urine protein\u002Fcreatinine \\>3 mg\u002Fmg (339 mg\u002Fmmol).\n* Active, severe central nervous system manifestations of SjD.\n* History of stroke, seizure, dementia, Parkinson's disease, coordination movement disorder, cerebellar diseases, psychosis, paresis, aphasia, and any other neurologic disorder that the Investigator feels would put the patient at undue risk or confound study results.\n* Evidence of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), Epstein-Barr virus (EBV), or cytomegalovirus (CMV) infection.\n* Primary immunodeficiency or history of recurrent infections.\n* History of splenectomy.\n* Live or attenuated vaccine within 28 days prior to the Screening Visit or during the Screening Period.\n* Active, clinically significant bacterial, viral, fungal, mycobacterial, 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