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The last dose≥ 5 half-lives prior to randomization.\n\nExclusion Criteria: key exclusion criteria: 1）Inducible urticaria ; 2） Diseases with possible symptoms of urticaria or angioedema such as urticarial vasculitis, erythema multiforme, cutaneous mastocytosis ；3） Presence of skin morbidities other than CSU that may interfere with the assessment of the study outcomes; 4)History of herpes simplex infection; 5 ）Serological abnormalities of infection at screening .\n\n\\-",true,"ALL","18 Years","75 Years",{"count":233,"type":234},48,"ESTIMATED","INTERVENTIONAL",[237,238],"PHASE1","PHASE2","This is a Phase IIa, randomized, blinded, placebo controlled,Multiple-Ascending Dose study of BBT001 in adult patients with Chronic Spontaneous Urticaria.",[241],"Chronic Spontaneous Urticaria","2026-07-21",{"date":244,"type":245},"2026-07-22","ACTUAL",{"date":247,"type":245},"2026-06-29",{"date":249,"type":234},"2028-06-30",{"name":5,"class":6},10]