[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650166":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":29,"locations":21,"responsibleParty":34,"collaborators":21,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":21,"eligibilityCriteria":42,"healthyVolunteers":43,"sex":44,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":21,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":21,"overallStatus":56,"whyStopped":21,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":21},{"fullName":5,"class":6},"Deciphera Pharmaceuticals, LLC","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Vimseltinib + Dabigatran","EXPERIMENTAL","Day 1 single dose of dabigatran, and Day 5 coadministration of dabigatran with vimseltinib.",[13,14],"Drug: Vimseltinib","Drug: Dabigatran",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DRUG","Vimseltinib","Administered orally",[9],null,{"type":17,"name":23,"description":19,"armGroupLabels":24,"otherNames":21},"Dabigatran",[9],[26],{"name":27,"affiliation":5,"role":28},"Clinical Team","STUDY_DIRECTOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":21,"email":33},"CONTACT","888-724-3274","clinicaltrials@deciphera.com",{"type":35,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100650166","phase-1-evaluate-the-effect-of-vimseltinib-on-p-glycoprotein-p-gp-inhibition-in-healthy-male-participants-100650166",false,"NCT07744802","Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants","A Phase 1, Open-label, Fixed-sequence Study to Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants","Inclusion Criteria:\n\n1. Participants are in good general health, as required by the protocol and as determined by Principal Investigator.\n2. Body mass index (BMI) from greater than or equal to (≥) 18 to less than or equal to ≤ 32 kilogram per square meter (kg\u002Fm\\^2).\n3. Adequate organ function and blood and urine tests, as required by the protocol and as determined by Principal Investigator.\n\nExclusion Criteria:\n\n1. History or presence of clinically significant diseases of the neurological, dermatological, renal, hepatic, gastrointestinal, cardiovascular, or musculoskeletal systems or history or presence of clinically significant psychiatric, immunological, endocrine, or metabolic disease as determined by Principal Investigator.\n2. Unwilling or unable to comply with the requirements of the protocol.\n3. Determined by Principal Investigator to be unsuitable to participate in the study for any other reason.",true,"MALE","18 Years","55 Years",{"count":48,"type":49},20,"ESTIMATED","INTERVENTIONAL",[52],"PHASE1","The main purpose of this study is to determine the effect of vimseltinib on pharmacokinetics of P-glycoprotein (P-gp) substrate (dabigatran) in healthy male participants. This study will last approximately 21 days.",[55],"Healthy Male Participants","NOT_YET_RECRUITING","2026-07-30",{"date":59,"type":60},"2026-08-04","ACTUAL",{"date":62,"type":49},"2026-08",{"date":64,"type":49},"2027-12",{"name":5,"class":6}]