[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554674":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":60,"collaborators":24,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":24,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":24,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":45,"whyStopped":24,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Montefiore Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mifepristone","EXPERIMENTAL","Patients will be randomized to Mifepristone-alone in a 1:1 manner prior to procedural abortions. A paracervical block of 20 cubic centimeters (cc) 1% lidocaine, with or without vasopressin, will be administered in accordance with standard practices.",[13],"Drug: Mifepristone",{"label":15,"type":10,"description":16,"interventionNames":17},"Misoprostol","Patients will be randomized to Misoprostol-alone in a 1:1 ratio prior to procedural abortions. A paracervical block of 20cc 1% lidocaine, with or without vasopressin, will be administered in accordance with standard practices.",[18],"Drug: Misoprostol",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","200 milligrams (mg)",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":28},"600 micrograms (ug)",[15],[29],"Cytotec",[31],{"name":32,"affiliation":5,"role":33},"Antoinette Danvers, MD, MSCR, MBA","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":24,"email":39},"Laura Fletcher, MD, MPH","CONTACT","516-587-3297","lfletcher@montefiore.org",{"name":32,"role":37,"phone":41,"phoneExt":24,"email":42},"718-405-8260","adanvers@montefiore.org",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","The Bronx","New York","10467","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-73.86641,40.84985,{"lat":55,"lon":54},[58,59],{"name":36,"role":37,"phone":38,"phoneExt":24,"email":39},{"name":32,"role":33,"phone":24,"phoneExt":24,"email":24},{"type":61,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100554674","phase-1-mifepristone-vs-misoprostol-100554674",false,"NCT06502158","Mifepristone vs Misoprostol","Mifepristone Versus Misoprostol for Cervical Preparation Prior to Procedural Abortion at 12 to 16 Weeks' Gestation in an Academic Medical Center: a Randomized Controlled Pilot Trial","Inclusion Criteria:\n\n* English or Spanish-speaking\n* Capacity to consent\n* Seeking induced abortion of a singleton pregnancy between 12 weeks, 0 days and 16 weeks, 6 days (based on age at day of surgery)\n\nExclusion Criteria:\n\n* History of more than two prior Cesarean deliveries\n* Sonographic evidence of placenta previa\n* Sonographic concern for morbidly adherent placenta\n* Prior obstetric hemorrhage requiring transfusion\n* Obstructive cervical or lower uterine segment fibroid\n* Current therapeutic anticoagulation use\n* Cerclage in situ\n* History of more than one prior cervical excisional procedure\n* BMI greater than 50 kg\u002Fm\\^2",true,"FEMALE","18 Years","45 Years",{"count":74,"type":75},94,"ESTIMATED","INTERVENTIONAL",[78],"PHASE1","The Investigator team hypothesizes that in a randomized trial comparing mifepristone-alone or misoprostol-alone for cervical preparation for procedural abortions at 12 to 16 weeks in hospital-based care, the proportion of patients who achieve successful cervical dilation will be different between the study groups.",[81],"Cervical Preparation",[83,84,85,86],"Procedural Abortion","Surgical Abortion","Abortion, First Trimester","Cervical Dilators","2026-07-23",{"date":89,"type":90},"2026-07-24","ACTUAL",{"date":92,"type":90},"2024-10-31",{"date":94,"type":75},"2027-06",{"name":5,"class":6},1]