[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100335921":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":36,"responsibleParty":58,"collaborators":31,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":31,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":31,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":31,"overallStatus":78,"whyStopped":31,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Contrast Enhanced Ultrasound","EXPERIMENTAL","Participants will undergo a contrast enhanced ultrasound (CEUS) using Lumason",[13],"Drug: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]","Lumason will be used as the contrast agent. Standard Lumason dose will be used: 0.03mL\u002Fkg up to a maximum dose of 2.4 milliliter (mL) per injection",[9],[21],"Lumason",[23],{"name":24,"affiliation":5,"role":25},"Richard Lee","PRINCIPAL_INVESTIGATOR",[27,33],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Vera Rodic, MPH","CONTACT","8572621693",null,"vera.rodic@childrens.harvard.edu",{"name":34,"role":29,"phone":31,"phoneExt":31,"email":35},"Katherine Regis","Katherine.Regis@childrens.harvard.edu",[37],{"facility":5,"status":31,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Boston","Massachusetts","02115","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-71.05977,42.35843,{"lat":47,"lon":46},[50,54],{"name":51,"role":29,"phone":52,"phoneExt":31,"email":53},"Amy Chan, B.A.","347-854-6840","amy.chan@childrens.harvard.edu",{"name":55,"role":29,"phone":56,"phoneExt":31,"email":57},"Emily Morrison, B.S.","617-919-2637","emily.morrison@childrens.harvard.edu",{"type":25,"investigatorFullName":24,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Principal Investigator","100335921","phase-1-radiation-free-technique-for-evaluating-renal-scarring-rafters-100335921",false,"NCT03653702","Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)","Inclusion Criteria:\n\n* patients older than or equal to 6 months and less than or equal to 35 years old and scheduled for Boston Children's Hospital (BCH) DMSA scan to evaluate renal function and\u002For renal scarring\n\nExclusion Criteria:\n\n* patients with significant congenital renal anatomical abnormalities including horseshoe kidney, kidney malrotation, and multicystic dysplastic kidney (MCDK). Patients with severe cardio-pulmonary diseases will also be excluded.","ALL","6 Months","35 Years",{"count":70,"type":71},70,"ESTIMATED","INTERVENTIONAL",[74],"PHASE1","In this research study the investigators want to study a safe, radiation-free technique known as contrast-enhanced ultrasound that may improve the ability to diagnose or evaluate renal scarring compared to regular ultrasound. This technique requires injection into a vein of a small amount of contrast material called Lumason. Contrast material is a type of dye that helps the investigators image the structures in the body more clearly. If this technique is successful, the need for DMSA studies may be avoided to diagnose or evaluate kidney scarring. DMSA is a more expensive test, causes radiation exposure, may require sedation and\u002For injection of contrast agents with the potential to cause allergic reactions.",[77],"Vesico-Ureteral Reflux","NOT_YET_RECRUITING","2026-07-20",{"date":81,"type":82},"2026-07-22","ACTUAL",{"date":84,"type":71},"2027-07-01",{"date":86,"type":71},"2029-07",{"name":5,"class":6},1]