[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647635":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":20,"locations":21,"responsibleParty":44,"collaborators":46,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":20,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":20,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":24,"whyStopped":20,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Singapore Eye Research Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cell Injection","EXPERIMENTAL","Direct endothelial cell injection",[13],"Biological: Cell injection",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BIOLOGICAL","Cell injection","Direct endothelial cell injection of non-cultured corneal endothelial cells",[9],null,[22],{"facility":23,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"L V Prasad Eye Institute","RECRUITING","Hyderabad","Telangana","500034","India","IN",{"type":31,"coordinates":32},"Point",[33,34],78.45636,17.38405,{"lat":34,"lon":33},[37,42],{"name":38,"role":39,"phone":40,"phoneExt":20,"email":41},"Sunita Chaurasia","CONTACT","9396475020","sunita@lvpei.org",{"name":38,"role":43,"phone":20,"phoneExt":20,"email":20},"PRINCIPAL_INVESTIGATOR",{"type":45,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[47],{"name":48,"class":6},"L.V. Prasad Eye Institute","100647635","phase-1-simple-non-cultured-endothelial-cell-therapy-for-corneal-endothelial-dysfunction-100647635",false,"NCT07711561","Simple Non-cultured Endothelial Cell Therapy for Corneal Endothelial Dysfunction","Safety and Efficacy of Simple Non-cultured Endothelial Cell Injection(SNEC-I) Therapy for Corneal Endothelial Dysfunction","Inclusion Criteria:\n\nPatients who have mild to moderate corneal endothelial decompensation or bullous keratopathy, but with minimal corneal stromal scarring resulting from irreversible post-surgical corneal decompensation, specifically, all forms of pseudophakic or aphakic bullous keratopathy.\n\nExclusion Criteria:\n\n1. Severe forms or late-stage presentation of corneal decompensation with severe corneal stromal scarring and or scarring to the DM, unsuitable for SNEC-I.\n2. Patients with complex anterior segment complications precluding a successful SNEC-I procedure\n3. Patients who have other forms of endothelial dystrophy, traumatic corneal decompensation, or post-inflammatory corneal decompensation\n4. Post-laser iridotomy or glaucoma related corneal decompensation\n5. Patients not keen to participate in the clinical trial\n6. Patients who are below 21 years of age or above 80 years of age\n7. Patients who are pregnant\n8. Patients who are cognitively impaired\n9. Patients who are prisoners\n10. Patients with antibiotics\u002Fantimycotics allergies","ALL","18 Years","80 Years",{"count":60,"type":61},20,"ESTIMATED","INTERVENTIONAL",[64],"PHASE1","Assessment of safety and efficacy of cell injection therapy generated using non-cultured human corneal endothelial cells in treating corneal endothelial dysfunction",[67,68],"Bullous Keratopathy","Corneal Endothelial Dystrophy",[70,71,72,73],"Cell therapy","Corneal endothelial dystophy","corneal endothelial dysfunction","cell injection","2026-07-13",{"date":76,"type":77},"2026-07-17","ACTUAL",{"date":79,"type":77},"2026-06-22",{"date":81,"type":61},"2029-07",{"name":5,"class":6},1]