[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610500":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":669,"collaborators":30,"id":671,"slug":672,"hasResults":673,"nctId":674,"briefTitle":675,"officialTitle":676,"acronym":30,"eligibilityCriteria":677,"healthyVolunteers":673,"sex":678,"minAge":679,"maxAge":680,"enrollmentInfo":681,"targetDuration":30,"studyType":684,"phases":685,"briefSummary":687,"conditions":688,"keywords":690,"overallStatus":43,"whyStopped":30,"lastUpdateSubmitDate":691,"lastUpdatePostDateStruct":692,"startDateStruct":695,"completionDateStruct":697,"leadSponsor":699,"locationsCount":700},{"fullName":5,"class":6},"Pfizer","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Study Intervention","EXPERIMENTAL","Participants will receive one oral dose once daily (QD), starting with a loading dose of ritlecitinib for 8 weeks, followed by maintenance for 8 weeks.",[13],"Drug: Ritlecitinib",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Participants will receive matching placebo.",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DRUG","Ritlecitinib",[9],[26],"Investigational Product",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"Participant will receive matching placebo",[15],null,[32],{"name":33,"affiliation":5,"role":34},"Pfizer CT.gov Call Center","STUDY_DIRECTOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":30,"email":39},"CONTACT","1-800-718-1021","ClinicalTrials.gov_Inquiries@pfizer.com",[41,55,62,67,76,86,96,105,114,123,132,142,151,160,169,178,184,190,194,200,209,219,229,239,245,251,260,269,279,284,294,304,314,324,334,344,354,364,373,383,393,405,414,420,429,439,448,457,463,472,484,493,502,514,524,534,540,552,561,570,579,588,597,603,609,615,621,633,642,651,660],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":30},"Medical Dermatology Specialists","RECRUITING","Phoenix","Arizona","85006","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-112.07404,33.44838,{"lat":53,"lon":52},{"facility":56,"status":57,"city":44,"state":45,"zip":58,"country":47,"countryCode":48,"cosmosGeoPoint":59,"geoPoint":61,"contacts":30},"Mayo Clinic Hospital","NOT_YET_RECRUITING","85054",{"type":50,"coordinates":60},[52,53],{"lat":53,"lon":52},{"facility":63,"status":57,"city":44,"state":45,"zip":58,"country":47,"countryCode":48,"cosmosGeoPoint":64,"geoPoint":66,"contacts":30},"Mayo Clinic Specialty Building",{"type":50,"coordinates":65},[52,53],{"lat":53,"lon":52},{"facility":68,"status":57,"city":69,"state":45,"zip":70,"country":47,"countryCode":48,"cosmosGeoPoint":71,"geoPoint":75,"contacts":30},"Mayo Clinic","Scottsdale","85259",{"type":50,"coordinates":72},[73,74],-111.89903,33.50921,{"lat":74,"lon":73},{"facility":77,"status":43,"city":78,"state":79,"zip":80,"country":47,"countryCode":48,"cosmosGeoPoint":81,"geoPoint":85,"contacts":30},"Burke Pharmaceutical Research","Hot Springs","Arkansas","71913",{"type":50,"coordinates":82},[83,84],-93.05518,34.5037,{"lat":84,"lon":83},{"facility":87,"status":43,"city":88,"state":89,"zip":90,"country":47,"countryCode":48,"cosmosGeoPoint":91,"geoPoint":95,"contacts":30},"First OC Dermatology Research Inc","Fountain Valley","California","92708",{"type":50,"coordinates":92},[93,94],-117.95367,33.70918,{"lat":94,"lon":93},{"facility":97,"status":43,"city":98,"state":89,"zip":99,"country":47,"countryCode":48,"cosmosGeoPoint":100,"geoPoint":104,"contacts":30},"Carbon Health - Urgent Care - La Habra","La Habra","90631",{"type":50,"coordinates":101},[102,103],-117.94617,33.93196,{"lat":103,"lon":102},{"facility":106,"status":43,"city":107,"state":89,"zip":108,"country":47,"countryCode":48,"cosmosGeoPoint":109,"geoPoint":113,"contacts":30},"Northridge Clinical Trials","Northridge","91325",{"type":50,"coordinates":110},[111,112],-118.53675,34.22834,{"lat":112,"lon":111},{"facility":115,"status":43,"city":116,"state":89,"zip":117,"country":47,"countryCode":48,"cosmosGeoPoint":118,"geoPoint":122,"contacts":30},"Integrative Skin Science and Research","Sacramento","95815",{"type":50,"coordinates":119},[120,121],-121.4944,38.58157,{"lat":121,"lon":120},{"facility":124,"status":43,"city":125,"state":89,"zip":126,"country":47,"countryCode":48,"cosmosGeoPoint":127,"geoPoint":131,"contacts":30},"Wolverine Clinical Trials","Santa Ana","92706",{"type":50,"coordinates":128},[129,130],-117.86783,33.74557,{"lat":130,"lon":129},{"facility":133,"status":43,"city":134,"state":135,"zip":136,"country":47,"countryCode":48,"cosmosGeoPoint":137,"geoPoint":141,"contacts":30},"Skin Care Research","Boca Raton","Florida","33486",{"type":50,"coordinates":138},[139,140],-80.0831,26.35869,{"lat":140,"lon":139},{"facility":143,"status":43,"city":144,"state":135,"zip":145,"country":47,"countryCode":48,"cosmosGeoPoint":146,"geoPoint":150,"contacts":30},"Olympian Clinical Research","Largo","33770",{"type":50,"coordinates":147},[148,149],-82.78842,27.90979,{"lat":149,"lon":148},{"facility":152,"status":43,"city":153,"state":135,"zip":154,"country":47,"countryCode":48,"cosmosGeoPoint":155,"geoPoint":159,"contacts":30},"Ziaderm Research LLC","North Miami Beach","33162",{"type":50,"coordinates":156},[157,158],-80.16255,25.93315,{"lat":158,"lon":157},{"facility":161,"status":43,"city":162,"state":135,"zip":163,"country":47,"countryCode":48,"cosmosGeoPoint":164,"geoPoint":168,"contacts":30},"D&H Tamarac Research Center","Tamarac","33321",{"type":50,"coordinates":165},[166,167],-80.24977,26.21286,{"lat":167,"lon":166},{"facility":170,"status":43,"city":171,"state":135,"zip":172,"country":47,"countryCode":48,"cosmosGeoPoint":173,"geoPoint":177,"contacts":30},"NMC Research LLC","Tampa","33607",{"type":50,"coordinates":174},[175,176],-82.45843,27.94752,{"lat":176,"lon":175},{"facility":179,"status":43,"city":171,"state":135,"zip":180,"country":47,"countryCode":48,"cosmosGeoPoint":181,"geoPoint":183,"contacts":30},"USF - Carol and Frank Morsani Center for Advanced Healthcare-Clinical Research Center","33612",{"type":50,"coordinates":182},[175,176],{"lat":176,"lon":175},{"facility":185,"status":43,"city":171,"state":135,"zip":186,"country":47,"countryCode":48,"cosmosGeoPoint":187,"geoPoint":189,"contacts":30},"Alliance Clinical Research of Tampa","33615",{"type":50,"coordinates":188},[175,176],{"lat":176,"lon":175},{"facility":143,"status":43,"city":171,"state":135,"zip":186,"country":47,"countryCode":48,"cosmosGeoPoint":191,"geoPoint":193,"contacts":30},{"type":50,"coordinates":192},[175,176],{"lat":176,"lon":175},{"facility":195,"status":43,"city":171,"state":135,"zip":196,"country":47,"countryCode":48,"cosmosGeoPoint":197,"geoPoint":199,"contacts":30},"USF Florida Hearing Clinic","33620",{"type":50,"coordinates":198},[175,176],{"lat":176,"lon":175},{"facility":201,"status":43,"city":202,"state":135,"zip":203,"country":47,"countryCode":48,"cosmosGeoPoint":204,"geoPoint":208,"contacts":30},"TruDerm & TruSpa","Wellington","33449",{"type":50,"coordinates":205},[206,207],-80.24144,26.65868,{"lat":207,"lon":206},{"facility":210,"status":43,"city":211,"state":212,"zip":213,"country":47,"countryCode":48,"cosmosGeoPoint":214,"geoPoint":218,"contacts":30},"Advanced Medical Research, PC.","Sandy Springs","Georgia","30328",{"type":50,"coordinates":215},[216,217],-84.37854,33.92427,{"lat":217,"lon":216},{"facility":220,"status":43,"city":221,"state":222,"zip":223,"country":47,"countryCode":48,"cosmosGeoPoint":224,"geoPoint":228,"contacts":30},"Endeavor Health","Skokie","Illinois","60077",{"type":50,"coordinates":225},[226,227],-87.73339,42.03336,{"lat":227,"lon":226},{"facility":230,"status":43,"city":231,"state":232,"zip":233,"country":47,"countryCode":48,"cosmosGeoPoint":234,"geoPoint":238,"contacts":30},"Whisper Hearing Center","Indianapolis","Indiana","46240",{"type":50,"coordinates":235},[236,237],-86.15804,39.76838,{"lat":237,"lon":236},{"facility":240,"status":43,"city":231,"state":232,"zip":241,"country":47,"countryCode":48,"cosmosGeoPoint":242,"geoPoint":244,"contacts":30},"Dawes Fretzin Clinical Research Group, LLC","46250",{"type":50,"coordinates":243},[236,237],{"lat":237,"lon":236},{"facility":246,"status":43,"city":231,"state":232,"zip":247,"country":47,"countryCode":48,"cosmosGeoPoint":248,"geoPoint":250,"contacts":30},"Community Imaging Center","46256",{"type":50,"coordinates":249},[236,237],{"lat":237,"lon":236},{"facility":252,"status":43,"city":253,"state":232,"zip":254,"country":47,"countryCode":48,"cosmosGeoPoint":255,"geoPoint":259,"contacts":30},"The Indiana Clinical Trials Center, PC","Plainfield","46168",{"type":50,"coordinates":256},[257,258],-86.39944,39.70421,{"lat":258,"lon":257},{"facility":261,"status":43,"city":262,"state":232,"zip":263,"country":47,"countryCode":48,"cosmosGeoPoint":264,"geoPoint":268,"contacts":30},"Options Research Group","West Lafayette","47906",{"type":50,"coordinates":265},[266,267],-86.90807,40.42587,{"lat":267,"lon":266},{"facility":270,"status":43,"city":271,"state":272,"zip":273,"country":47,"countryCode":48,"cosmosGeoPoint":274,"geoPoint":278,"contacts":30},"Essential Medical Research - Overland Park","Overland Park","Kansas","66213",{"type":50,"coordinates":275},[276,277],-94.67079,38.98223,{"lat":277,"lon":276},{"facility":280,"status":43,"city":271,"state":272,"zip":273,"country":47,"countryCode":48,"cosmosGeoPoint":281,"geoPoint":283,"contacts":30},"Skin and Hair Center",{"type":50,"coordinates":282},[276,277],{"lat":277,"lon":276},{"facility":285,"status":43,"city":286,"state":287,"zip":288,"country":47,"countryCode":48,"cosmosGeoPoint":289,"geoPoint":293,"contacts":30},"DS Research of Kentucky","Louisville","Kentucky","40241",{"type":50,"coordinates":290},[291,292],-85.75941,38.25424,{"lat":292,"lon":291},{"facility":295,"status":43,"city":296,"state":297,"zip":298,"country":47,"countryCode":48,"cosmosGeoPoint":299,"geoPoint":303,"contacts":30},"Beth Israel Deaconess Medical Center","Boston","Massachusetts","02215",{"type":50,"coordinates":300},[301,302],-71.05977,42.35843,{"lat":302,"lon":301},{"facility":305,"status":43,"city":306,"state":307,"zip":308,"country":47,"countryCode":48,"cosmosGeoPoint":309,"geoPoint":313,"contacts":30},"Revival Research Institute, LLC","Southfield","Michigan","48034",{"type":50,"coordinates":310},[311,312],-83.22187,42.47337,{"lat":312,"lon":311},{"facility":315,"status":43,"city":316,"state":317,"zip":318,"country":47,"countryCode":48,"cosmosGeoPoint":319,"geoPoint":323,"contacts":30},"Skin Specialists, PC dba Schlessinger MD","Omaha","Nebraska","68144",{"type":50,"coordinates":320},[321,322],-95.94043,41.25626,{"lat":322,"lon":321},{"facility":325,"status":43,"city":326,"state":327,"zip":328,"country":47,"countryCode":48,"cosmosGeoPoint":329,"geoPoint":333,"contacts":30},"Stracskin","Portsmouth","New Hampshire","03801",{"type":50,"coordinates":330},[331,332],-70.75766,43.07704,{"lat":332,"lon":331},{"facility":335,"status":43,"city":336,"state":337,"zip":338,"country":47,"countryCode":48,"cosmosGeoPoint":339,"geoPoint":343,"contacts":30},"DJL Clinical Research, PLLC","Charlotte","North Carolina","28211",{"type":50,"coordinates":340},[341,342],-80.84313,35.22709,{"lat":342,"lon":341},{"facility":345,"status":43,"city":346,"state":347,"zip":348,"country":47,"countryCode":48,"cosmosGeoPoint":349,"geoPoint":353,"contacts":30},"ClinOhio Research Services","Columbus","Ohio","43213",{"type":50,"coordinates":350},[351,352],-82.99879,39.96118,{"lat":352,"lon":351},{"facility":355,"status":43,"city":356,"state":357,"zip":358,"country":47,"countryCode":48,"cosmosGeoPoint":359,"geoPoint":363,"contacts":30},"Columbia Dermatology & Aesthetics","Columbia","South Carolina","29212",{"type":50,"coordinates":360},[361,362],-81.03481,34.00071,{"lat":362,"lon":361},{"facility":365,"status":43,"city":366,"state":357,"zip":367,"country":47,"countryCode":48,"cosmosGeoPoint":368,"geoPoint":372,"contacts":30},"Palmetto Clinical Trial Services - Greenville","Greenville","29615",{"type":50,"coordinates":369},[370,371],-82.39401,34.85262,{"lat":371,"lon":370},{"facility":374,"status":43,"city":375,"state":376,"zip":377,"country":47,"countryCode":48,"cosmosGeoPoint":378,"geoPoint":382,"contacts":30},"Center for Clinical Studies, LTD. LLP","Houston","Texas","77004",{"type":50,"coordinates":379},[380,381],-95.36327,29.76328,{"lat":381,"lon":380},{"facility":384,"status":43,"city":385,"state":386,"zip":387,"country":47,"countryCode":48,"cosmosGeoPoint":388,"geoPoint":392,"contacts":30},"Eurofins CRL","Forest","Virginia","24551",{"type":50,"coordinates":389},[390,391],-79.28975,37.36375,{"lat":391,"lon":390},{"facility":394,"status":43,"city":395,"state":396,"zip":397,"country":398,"countryCode":399,"cosmosGeoPoint":400,"geoPoint":404,"contacts":30},"Dermatology Research Institute","Calgary","Alberta","T2J 7E1","Canada","CA",{"type":50,"coordinates":401},[402,403],-114.08529,51.05011,{"lat":403,"lon":402},{"facility":406,"status":43,"city":407,"state":396,"zip":408,"country":398,"countryCode":399,"cosmosGeoPoint":409,"geoPoint":413,"contacts":30},"Laser Rejuvenation Clinics Edmonton D.T. Inc","Edmonton","T5J 3S9",{"type":50,"coordinates":410},[411,412],-113.46871,53.55014,{"lat":412,"lon":411},{"facility":415,"status":43,"city":407,"state":396,"zip":416,"country":398,"countryCode":399,"cosmosGeoPoint":417,"geoPoint":419,"contacts":30},"Skin Physicians Dermatology","T6W 4V4",{"type":50,"coordinates":418},[411,412],{"lat":412,"lon":411},{"facility":421,"status":43,"city":422,"state":396,"zip":423,"country":398,"countryCode":399,"cosmosGeoPoint":424,"geoPoint":428,"contacts":30},"CaRe Clinic","Red Deer","T4P 1K4",{"type":50,"coordinates":425},[426,427],-113.802,52.26682,{"lat":427,"lon":426},{"facility":430,"status":43,"city":431,"state":432,"zip":433,"country":398,"countryCode":399,"cosmosGeoPoint":434,"geoPoint":438,"contacts":30},"Ryan Clinical Research Inc.","Newmarket","Ontario","L3Y 5G8",{"type":50,"coordinates":435},[436,437],-79.46631,44.05011,{"lat":437,"lon":436},{"facility":440,"status":43,"city":441,"state":432,"zip":442,"country":398,"countryCode":399,"cosmosGeoPoint":443,"geoPoint":447,"contacts":30},"DAR Clinical Research","Ottawa","K1V 1C1",{"type":50,"coordinates":444},[445,446],-75.69812,45.41117,{"lat":446,"lon":445},{"facility":449,"status":43,"city":450,"state":432,"zip":451,"country":398,"countryCode":399,"cosmosGeoPoint":452,"geoPoint":456,"contacts":30},"North York Research Inc","Toronto","M2N 3A6",{"type":50,"coordinates":453},[454,455],-79.39864,43.70643,{"lat":455,"lon":454},{"facility":458,"status":43,"city":450,"state":432,"zip":459,"country":398,"countryCode":399,"cosmosGeoPoint":460,"geoPoint":462,"contacts":30},"FACET Dermatology","M4E 1R7",{"type":50,"coordinates":461},[454,455],{"lat":455,"lon":454},{"facility":464,"status":43,"city":465,"state":30,"zip":466,"country":398,"countryCode":399,"cosmosGeoPoint":467,"geoPoint":471,"contacts":30},"Centre de Recherche Saint-Louis inc.","Québec","G1W 4R4",{"type":50,"coordinates":468},[469,470],-71.21454,46.81228,{"lat":470,"lon":469},{"facility":473,"status":43,"city":474,"state":475,"zip":476,"country":477,"countryCode":478,"cosmosGeoPoint":479,"geoPoint":483,"contacts":30},"Universitaetsklinikum Carl Gustav Carus, Technischen Universitaet Dresden","Dresden","Saxony","01307","Germany","DE",{"type":50,"coordinates":480},[481,482],13.73832,51.05089,{"lat":482,"lon":481},{"facility":485,"status":43,"city":486,"state":30,"zip":487,"country":477,"countryCode":478,"cosmosGeoPoint":488,"geoPoint":492,"contacts":30},"Universitätsklinikum Frankfurt","Frankfurt","60590",{"type":50,"coordinates":489},[490,491],10.53333,49.68333,{"lat":491,"lon":490},{"facility":494,"status":43,"city":495,"state":30,"zip":496,"country":477,"countryCode":478,"cosmosGeoPoint":497,"geoPoint":501,"contacts":30},"Universitätsklinikum Schleswig Holstein - Campus Lübeck","Lübeck","23538",{"type":50,"coordinates":498},[499,500],10.68729,53.86893,{"lat":500,"lon":499},{"facility":503,"status":43,"city":504,"state":505,"zip":506,"country":507,"countryCode":508,"cosmosGeoPoint":509,"geoPoint":513,"contacts":30},"Athens Medical Center - Psychikon branch","Athens","Attica","11525","Greece","GR",{"type":50,"coordinates":510},[511,512],23.72784,37.98376,{"lat":512,"lon":511},{"facility":515,"status":43,"city":516,"state":517,"zip":518,"country":507,"countryCode":508,"cosmosGeoPoint":519,"geoPoint":523,"contacts":30},"Papageorgiou General Hospital of Thessaloniki","Thessaloniki","Thessaloníki","564 29",{"type":50,"coordinates":520},[521,522],22.93493,40.64072,{"lat":522,"lon":521},{"facility":525,"status":43,"city":526,"state":527,"zip":528,"country":507,"countryCode":508,"cosmosGeoPoint":529,"geoPoint":533,"contacts":30},"University General Hospital of Larissa","Larissa","Thessalía","411 10",{"type":50,"coordinates":530},[531,532],22.42112,39.62847,{"lat":532,"lon":531},{"facility":535,"status":43,"city":504,"state":30,"zip":536,"country":507,"countryCode":508,"cosmosGeoPoint":537,"geoPoint":539,"contacts":30},"Dermatological and Venereological Hospital Andreas Syggros","161 21",{"type":50,"coordinates":538},[511,512],{"lat":512,"lon":511},{"facility":541,"status":43,"city":542,"state":543,"zip":544,"country":545,"countryCode":546,"cosmosGeoPoint":547,"geoPoint":551,"contacts":30},"Cityclinic Przychodnia Lekarsko-Psychologiczna Matusiak Spółka Partnerska","Wroclaw","Lower Silesian Voivodeship","50-566","Poland","PL",{"type":50,"coordinates":548},[549,550],17.03006,51.10286,{"lat":550,"lon":549},{"facility":553,"status":43,"city":554,"state":30,"zip":555,"country":545,"countryCode":546,"cosmosGeoPoint":556,"geoPoint":560,"contacts":30},"Penta Hospitals Badania Kliniczne sp. z o.o.","Gdansk","80-546",{"type":50,"coordinates":557},[558,559],18.64912,54.35227,{"lat":559,"lon":558},{"facility":562,"status":43,"city":563,"state":30,"zip":564,"country":545,"countryCode":546,"cosmosGeoPoint":565,"geoPoint":569,"contacts":30},"Dermedic Jacek Zdybski","Ostrowiec Świętokrzyski","27-400",{"type":50,"coordinates":566},[567,568],21.38525,50.92936,{"lat":568,"lon":567},{"facility":571,"status":43,"city":572,"state":30,"zip":573,"country":545,"countryCode":546,"cosmosGeoPoint":574,"geoPoint":578,"contacts":30},"Centrum Zdrowia Dziecka i Rodziny im Jana Pawla II w Sosnowcu","Sosnowiec","41-200",{"type":50,"coordinates":575},[576,577],19.10385,50.28682,{"lat":577,"lon":576},{"facility":580,"status":43,"city":581,"state":30,"zip":582,"country":545,"countryCode":546,"cosmosGeoPoint":583,"geoPoint":587,"contacts":30},"Twoja Przychodnia Szczecinskie Centrum Medyczne Sp. z o.o.","Szczecin","71-500",{"type":50,"coordinates":584},[585,586],14.55302,53.42894,{"lat":586,"lon":585},{"facility":589,"status":43,"city":590,"state":30,"zip":591,"country":545,"countryCode":546,"cosmosGeoPoint":592,"geoPoint":596,"contacts":30},"Trialmed CRS - Warszawa","Warsaw","02-482",{"type":50,"coordinates":593},[594,595],21.01178,52.22977,{"lat":595,"lon":594},{"facility":598,"status":43,"city":590,"state":30,"zip":599,"country":545,"countryCode":546,"cosmosGeoPoint":600,"geoPoint":602,"contacts":30},"Państwowy Instytut Medyczny MSWiA","02-507",{"type":50,"coordinates":601},[594,595],{"lat":595,"lon":594},{"facility":604,"status":43,"city":590,"state":30,"zip":605,"country":545,"countryCode":546,"cosmosGeoPoint":606,"geoPoint":608,"contacts":30},"Klinika Ambroziak Dermatologia","02-953",{"type":50,"coordinates":607},[594,595],{"lat":595,"lon":594},{"facility":610,"status":43,"city":590,"state":30,"zip":611,"country":545,"countryCode":546,"cosmosGeoPoint":612,"geoPoint":614,"contacts":30},"Royalderm Agnieszka Nawrocka","02-962",{"type":50,"coordinates":613},[594,595],{"lat":595,"lon":594},{"facility":616,"status":43,"city":542,"state":30,"zip":617,"country":545,"countryCode":546,"cosmosGeoPoint":618,"geoPoint":620,"contacts":30},"Soft Skin Medical Center Dr Elzbieta Wojtowicz-Prus","50-551",{"type":50,"coordinates":619},[549,550],{"lat":550,"lon":549},{"facility":622,"status":43,"city":623,"state":624,"zip":625,"country":626,"countryCode":627,"cosmosGeoPoint":628,"geoPoint":632,"contacts":30},"Hospital de Manises","Manises","Valencia","46940","Spain","ES",{"type":50,"coordinates":629},[630,631],-0.46349,39.49139,{"lat":631,"lon":630},{"facility":634,"status":43,"city":635,"state":30,"zip":636,"country":626,"countryCode":627,"cosmosGeoPoint":637,"geoPoint":641,"contacts":30},"Hospital Universitario Puerta del Mar","Cadiz","11009",{"type":50,"coordinates":638},[639,640],-6.2891,36.52672,{"lat":640,"lon":639},{"facility":643,"status":43,"city":644,"state":30,"zip":645,"country":626,"countryCode":627,"cosmosGeoPoint":646,"geoPoint":650,"contacts":30},"Hospital Universitario Virgen Nieves","Granada","18012",{"type":50,"coordinates":647},[648,649],-3.60667,37.18817,{"lat":649,"lon":648},{"facility":652,"status":43,"city":653,"state":30,"zip":654,"country":626,"countryCode":627,"cosmosGeoPoint":655,"geoPoint":659,"contacts":30},"Hospital General Universitario Gregorio Maranon","Madrid","28007",{"type":50,"coordinates":656},[657,658],-3.70256,40.4165,{"lat":658,"lon":657},{"facility":661,"status":43,"city":662,"state":30,"zip":663,"country":626,"countryCode":627,"cosmosGeoPoint":664,"geoPoint":668,"contacts":30},"CHOP-Centro De Especialidades De Mollabao","Pontevedra","36001",{"type":50,"coordinates":665},[666,667],-8.64435,42.431,{"lat":667,"lon":666},{"type":670,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100610500","phase-2-a-16-week-study-to-learn-about-the-study-medicine-called-ritlecitinib-in-adults-with-long-lasting-painful-red-skin-lumps-known-by-the-medical-term-hidradenitis-suppurativa-or-hs-100610500",false,"NCT07228390","A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.","A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, 16-WEEK STUDY EVALUATING THE SAFETY AND EFFICACY OF RITLECITINIB (PF-06651600) IN ADULTS WITH MODERATE TO SEVERE HIDRADENITIS SUPPURATIVA","Key Eligibility Criteria:\n\nInclusion Criteria:\n\n1. Male or female participants ≥18 to ≤75 years of age.\n2. Participants with a diagnosis (based on clinical history and physical examination) of moderate to severe HS for at least 6 months prior to Screening Visit and inadequate response to at least 4-week (28 days) treatment with oral antibiotics for the treatment of HS.\n\nExclusion Criteria:\n\n1. Presence of ≥20 draining fistulae at Screening or BL visit\n2. Evidence of other active skin disease or condition at screening\n3. Have a known immunodeficiency disorder\n4. Having a history of systemic infection requiring hospitalization or parenteral therapy, including history of infection with Mycobacterium TB\n5. Specific Viral Infection History (incl. history of herpes zoster, HBV or HCV Infection\n6. Current or recent history of clinically significant severe, progressive, or uncontrolled other medical conditions\n7. Any medical or psychiatric condition including any active suicidal ideation in the past year or suicidal behavior in the past 5 years","ALL","18 Years","75 Years",{"count":682,"type":683},240,"ESTIMATED","INTERVENTIONAL",[686],"PHASE2","The purpose of this study is to learn about the safety and effects of the study medicine (called Ritlecitinib) for the possible treatment of hidradenitis suppurativa (HS). HS is a disease causing long lasting painful red skin lumps.\n\nThis study is seeking participants who:\n\n* have moderate or severe HS\n* have previously received antibiotics for HS that did not help, or could not tolerate antibiotics Participants will be randomly (like a flip of coin) assigned to receive either the study medicine or a placebo (a pill that looks like the study medicine but does not contain any medicine). The study medicine or placebo will be taken by mouth once daily at home. For the first part of the study, participants will receive a loading (starting) dose. For the next part of the study, participants will receive a maintenance (ongoing) dose.\n\nParticipants will take part in the study for about 24 weeks (about 6 months). There will be about 10 study clinic visits: a screening visit, Day 1, and then every 1, 2, or 4 weeks until week 16. At each visit, participants will report on their health and have tests such as physical exams, blood and urine tests, vital signs, chest X-rays, ECGs, hearing tests, and questionnaires. Participants will record when they take the study medicine and their HS symptoms every day in an eDiary on a mobile phone.\n\nThe experiences of participants receiving the study medicine will be compared to those receiving placebo to help see if the study medicine is safe and effective.",[689],"Hidradenitis Suppurativa",[23],"2026-07-07",{"date":693,"type":694},"2026-07-09","ACTUAL",{"date":696,"type":694},"2025-11-13",{"date":698,"type":683},"2027-04-02",{"name":5,"class":6},71]