[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595518":3},{"organization":4,"outcomesModule":7,"designInfo":44,"detailedDescription":57,"studyPopulation":43,"armGroups":58,"interventions":71,"overallOfficials":81,"centralContacts":85,"locations":91,"responsibleParty":1068,"collaborators":43,"id":1070,"slug":1071,"hasResults":1072,"nctId":1073,"briefTitle":1074,"officialTitle":1075,"acronym":43,"eligibilityCriteria":1076,"healthyVolunteers":1072,"sex":1077,"minAge":1078,"maxAge":1079,"enrollmentInfo":1080,"targetDuration":43,"studyType":1083,"phases":1084,"briefSummary":1086,"conditions":1087,"keywords":43,"overallStatus":94,"whyStopped":43,"lastUpdateSubmitDate":1089,"lastUpdatePostDateStruct":1090,"startDateStruct":1093,"completionDateStruct":1095,"leadSponsor":1097,"locationsCount":1098},{"fullName":5,"class":6},"Merck Sharp & Dohme LLC","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":21,"otherOutcomes":43},[9,13,17],{"measure":10,"description":11,"timeFrame":12},"Base Period: Change from Baseline in Tau PET Standardized Uptake Value Ratio (SUVr)","Participants will have tau PET imaging to assess tau pathology. Tau is a protein that accumulates in AD \\& damages brain cells. SUVr is SUV in the region of interest divided by SUV in a reference region (cerebellum). The change from baseline in tau PET SUVr will be reported.","Baseline, up to approximately 23 months",{"measure":14,"description":15,"timeFrame":16},"Base Period: Number of Participants Who Experience One or More Adverse Events (AEs)","An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention. The number of participants who experience one or more AEs will be reported.","Up to approximately 26 months",{"measure":18,"description":19,"timeFrame":20},"Base Period: Number of Participants Who Discontinue Study Intervention Due to an AE","An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention. The number of participants who discontinue study intervention due to an AE will be reported.","Up to approximately 23 months",[22,25,28,31,34,37,40],{"measure":23,"description":24,"timeFrame":12},"Base Period: Change from Baseline in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) Total Score","The CDR-SB is used for cognitive assessment in people with AD. The CDR is a clinical scale that describes 5 degrees of impairment in performance on each of 6 categories of function including memory, orientation, judgment and problem solving, community affairs, home and hobbies, and personal care. The ratings of degree of impairment obtained on each of the 6 categories of function are synthesized into 1 global rating of dementia CDR score ranging from 0 (normal) to 3 (severe). A total score is calculated as the sum of the category scores, with a range of 0 (normal) to 18 (severe). Higher scores indicate more impairment. The change from baseline in CDR-SB total score will be reported.",{"measure":26,"description":27,"timeFrame":12},"Base Period: Change from Baseline in the Composite Tau PET SUVr in Braak Region III and IV","Participants will have tau PET imaging to assess tau pathology. Tau is a protein that accumulates in AD \\& damages brain cells. SUVr is SUV in the region of interest, divided by SUV in a reference region (cerebellum). Braak staging ranges from Braak I to VI. Description for Braak III includes amygdala, parahippocampal gyrus, fusiform gyrus, \\& lingual gyrus, and Braak IV includes insula, inferior temporal, lateral temporal, posterior cingulate, \\& inferior parietal. The composite tau PET SUVr is a weighted average of tau PET SUVr values obtained from multiple brain regions, with weights being the percentage volume of each region within the composite. The change from baseline in composite tau PET SUVr in Braak regions III and IV will be reported.",{"measure":29,"description":30,"timeFrame":12},"Base Period: Change from Baseline in the Composite Tau PET SUVr","Participants will have tau PET imaging to assess tau pathology. Tau is a protein that accumulates in AD \\& damages brain cells. SUVr is SUV in the region of interest, divided by SUV in a reference region (cerebellum). The composite tau PET SUVr is a weighted average of tau PET SUVr values obtained from multiple brain regions, with weights being the percentage volume of each region within the composite. The change from baseline in composite tau PET SUVr will be reported.",{"measure":32,"description":33,"timeFrame":12},"Base Period: Change from Baseline in the Composite Tau PET SUVr in Braak Region I to VI","Participants will have tau PET imaging to assess tau (protein that accumulates in AD \\& damages brain cells) pathology. SUVr is SUV in the region of interest, divided by SUV in a reference region (cerebellum). Braak staging ranges from I-VI (Braak I (transentorhinal); II (entorhinal \\& hippocampus); III (amygdala, parahippocampal gyrus, fusiform gyrus, \\& lingual gyrus); IV (insula, inferior temporal, lateral temporal, posterior cingulate, \\& inferior parietal); V (orbitofrontal, superior temporal, inferior frontal, cuneus, anterior cingulate, supramarginal gyrus, lateral occipital, precuneus, superior parietal, superior frontal, \\& rostro medial frontal); VI (paracentral, postcentral, precentral, \\& pericalcarine)). Composite tau PET SUVr is weighted average of tau PET SUVr values from multiple brain regions, with weights being percentage volume of each region. The change from baseline in composite tau PET SUVr in Braak region I to IV will be reported.",{"measure":35,"description":36,"timeFrame":12},"Base Period: Change from Baseline in the Alzheimer's Disease Assessment Scale-Cognitive Subscale13 (ADAS-Cog13) Total Score","The ADAS-Cog13 is a structured scale that evaluates memory (word recall, delayed word recall, and word recognition), reasoning (following commands), language (naming, comprehension), orientation, ideational praxis (placing letter in envelope) and constructional praxis (copying geometric designs). In addition, ratings of spoken language, language comprehension, word finding difficulty, ability to remember test instructions, and number cancellation will be obtained. Per protocol, score range will be from 0 (no impairment) to 85 (maximum impairment) points. Higher scores indicate more impairment. The change from baseline in ADAS-Cog13 total score will be reported.",{"measure":38,"description":39,"timeFrame":12},"Base Period: Change from Baseline in the Alzheimer's Disease Cooperative Study Activities of Daily Living for Mild Cognitive Impairment (ADCS-ADL-MCI) Total Score","ADCS-ADL-MCI evaluates the ability of individuals to perform various daily activities including basic activities of daily living (BADL; personal care tasks like bathing, dressing and eating) and instrumental activities of daily living (IADL; complex tasks such as managing finances, preparing meals, using telephone) administered through caregiver or family member to access severity of cognitive decline in the past 4 weeks. Each item is scored on a scale of 0 (unable to do) to 2 (independent). The total score is calculated by summing scores of all items and ranges from 0 (poor functioning) to 68 (better functioning). Higher scores indicate better functional ability. The change from baseline in ADCS-ADL-MCI total score will be reported.",{"measure":41,"description":42,"timeFrame":12},"Base Period: Change from Baseline in Modified Integrated Alzheimer's Disease Rating Scale (iADRS) Total Score","The modified iADRS is a composite tool to measure cognition and function. The modified iADRS is a linear combination of total scores from the ADAS-Cog and the ADCS-ADL-MCI. The modified iADRS composite score is calculated by subtracting the ADAS-Cog13 score from 85 and then adding the ADCS-ADL-MCI score. Composite score ranges from 0 (maximum impairment) to 144 (greater independent, healthy functioning and cognition). Lower scores indicate more impairment. The change from baseline in modified iADRS total score will be reported.",null,{"allocation":45,"interventionModel":46,"interventionModelDescription":47,"primaryPurpose":48,"observationalModel":43,"timePerspective":43,"maskingInfo":49},"RANDOMIZED","PARALLEL","There are two parts of the study. The blinded period is randomized parallel treatment groups. Participants who complete the blinded period are then eligible to enroll in an open label extension (OLE) (single group).","TREATMENT",{"masking":50,"maskingDescription":51,"whoMasked":52},"QUADRUPLE","The blinded period is double-blinded. The extension period is open-label.",[53,54,55,56],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR","Per AM03, an optional open-label extension period has been added to the study.",[59,65],{"label":60,"type":61,"description":62,"interventionNames":63},"Base and Open-Label Extension Period: MK-2214","EXPERIMENTAL","Participants will receive MK-2214 via intravenous (IV) infusion every 4 weeks (q4w) during the base period. After the completion of the base period participants have the option to continue receiving MK-2214 throughout the open-label extension period.",[64],"Biological: MK-2214",{"label":66,"type":67,"description":68,"interventionNames":69},"Base Period: Placebo","PLACEBO_COMPARATOR","Participants will receive a placebo via IV infusion q4w during the base period.",[70],"Drug: Placebo",[72,77],{"type":73,"name":74,"description":75,"armGroupLabels":76,"otherNames":43},"BIOLOGICAL","MK-2214","IV infusion",[60],{"type":78,"name":79,"description":75,"armGroupLabels":80,"otherNames":43},"DRUG","Placebo",[66],[82],{"name":83,"affiliation":5,"role":84},"Medical Director","STUDY_DIRECTOR",[86],{"name":87,"role":88,"phone":89,"phoneExt":43,"email":90},"Toll Free Number","CONTACT","1-888-577-8839","Trialsites@msd.com",[92,110,122,134,146,158,170,183,196,208,220,232,244,256,268,280,292,304,313,325,337,350,363,376,389,402,414,426,439,451,463,476,489,501,514,527,539,549,555,562,577,589,602,614,629,642,655,670,682,691,704,719,732,745,758,771,784,792,805,816,828,840,855,867,879,893,901,914,923,932,947,959,968,977,992,1004,1017,1030,1043,1056],{"facility":93,"status":94,"city":95,"state":96,"zip":97,"country":98,"countryCode":99,"cosmosGeoPoint":100,"geoPoint":105,"contacts":106},"Irvine Clinical Research ( Site 1041)","RECRUITING","Irvine","California","92614","United States","US",{"type":101,"coordinates":102},"Point",[103,104],-117.82311,33.66946,{"lat":104,"lon":103},[107],{"name":108,"role":88,"phone":109,"phoneExt":43,"email":43},"Study Coordinator","949-753-1663",{"facility":111,"status":94,"city":112,"state":96,"zip":113,"country":98,"countryCode":99,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Healthy Brain Clinic ( Site 1005)","Long Beach","90804",{"type":101,"coordinates":115},[116,117],-118.18923,33.76696,{"lat":117,"lon":116},[120],{"name":108,"role":88,"phone":121,"phoneExt":43,"email":43},"562-606-5999",{"facility":123,"status":94,"city":124,"state":96,"zip":125,"country":98,"countryCode":99,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"Inglewood Clinical ( Site 1062)","Los Angeles","90056",{"type":101,"coordinates":127},[128,129],-118.24368,34.05223,{"lat":129,"lon":128},[132],{"name":108,"role":88,"phone":133,"phoneExt":43,"email":43},"949-265-1612",{"facility":135,"status":94,"city":136,"state":96,"zip":137,"country":98,"countryCode":99,"cosmosGeoPoint":138,"geoPoint":142,"contacts":143},"Anderson Clinical Research ( Site 1024)","Redlands","92374",{"type":101,"coordinates":139},[140,141],-117.18254,34.05557,{"lat":141,"lon":140},[144],{"name":108,"role":88,"phone":145,"phoneExt":43,"email":43},"909-792-9007",{"facility":147,"status":94,"city":148,"state":96,"zip":149,"country":98,"countryCode":99,"cosmosGeoPoint":150,"geoPoint":154,"contacts":155},"UCSF Memory and Aging Center ( Site 1031)","San Francisco","94158",{"type":101,"coordinates":151},[152,153],-122.41942,37.77493,{"lat":153,"lon":152},[156],{"name":108,"role":88,"phone":157,"phoneExt":43,"email":43},"415-353-3585",{"facility":159,"status":94,"city":160,"state":96,"zip":161,"country":98,"countryCode":99,"cosmosGeoPoint":162,"geoPoint":166,"contacts":167},"Syrentis Clinical Research ( Site 1001)","Santa Ana","92705",{"type":101,"coordinates":163},[164,165],-117.86783,33.74557,{"lat":165,"lon":164},[168],{"name":108,"role":88,"phone":169,"phoneExt":43,"email":43},"714-542-3008",{"facility":171,"status":94,"city":172,"state":173,"zip":174,"country":98,"countryCode":99,"cosmosGeoPoint":175,"geoPoint":179,"contacts":180},"Yale University, Alzheimer's Disease Research Unit ( Site 1059)","New Haven","Connecticut","06510",{"type":101,"coordinates":176},[177,178],-72.92816,41.30815,{"lat":178,"lon":177},[181],{"name":108,"role":88,"phone":182,"phoneExt":43,"email":43},"203-764-8100",{"facility":184,"status":94,"city":185,"state":186,"zip":187,"country":98,"countryCode":99,"cosmosGeoPoint":188,"geoPoint":192,"contacts":193},"JEM Research Institute ( Site 1046)","Atlantis","Florida","33462",{"type":101,"coordinates":189},[190,191],-80.10088,26.5909,{"lat":191,"lon":190},[194],{"name":108,"role":88,"phone":195,"phoneExt":43,"email":43},"561-968-2933",{"facility":197,"status":94,"city":198,"state":186,"zip":199,"country":98,"countryCode":99,"cosmosGeoPoint":200,"geoPoint":204,"contacts":205},"Neuropsychiatric Research Center of Southwest Florida ( Site 1003)","Fort Myers","33912",{"type":101,"coordinates":201},[202,203],-81.84059,26.62168,{"lat":203,"lon":202},[206],{"name":108,"role":88,"phone":207,"phoneExt":43,"email":43},"239-939-7777",{"facility":209,"status":94,"city":210,"state":186,"zip":211,"country":98,"countryCode":99,"cosmosGeoPoint":212,"geoPoint":216,"contacts":217},"K2 Medical Research ( Site 1047)","Maitland","32750",{"type":101,"coordinates":213},[214,215],-81.36312,28.62778,{"lat":215,"lon":214},[218],{"name":108,"role":88,"phone":219,"phoneExt":43,"email":43},"407-500-5252",{"facility":221,"status":94,"city":222,"state":186,"zip":223,"country":98,"countryCode":99,"cosmosGeoPoint":224,"geoPoint":228,"contacts":229},"ClinCloud LLC ( Site 1039)","Melbourne","32940",{"type":101,"coordinates":225},[226,227],-80.60811,28.08363,{"lat":227,"lon":226},[230],{"name":108,"role":88,"phone":231,"phoneExt":43,"email":43},"407-680-0534",{"facility":233,"status":94,"city":234,"state":186,"zip":235,"country":98,"countryCode":99,"cosmosGeoPoint":236,"geoPoint":240,"contacts":241},"Indago Research and Health Center Inc ( Site 1044)","Miami Lakes","33016",{"type":101,"coordinates":237},[238,239],-80.30866,25.90871,{"lat":239,"lon":238},[242],{"name":108,"role":88,"phone":243,"phoneExt":43,"email":43},"305-825-6588",{"facility":245,"status":94,"city":246,"state":186,"zip":247,"country":98,"countryCode":99,"cosmosGeoPoint":248,"geoPoint":252,"contacts":253},"Aqualane Clinical Research ( Site 1035)","Naples","34105",{"type":101,"coordinates":249},[250,251],-81.79596,26.14234,{"lat":251,"lon":250},[254],{"name":108,"role":88,"phone":255,"phoneExt":43,"email":43},"239-529-6780",{"facility":257,"status":94,"city":258,"state":186,"zip":259,"country":98,"countryCode":99,"cosmosGeoPoint":260,"geoPoint":264,"contacts":265},"Suncoast Clinical Research ( Site 1007)","New Port Richey","34652",{"type":101,"coordinates":261},[262,263],-82.71927,28.24418,{"lat":263,"lon":262},[266],{"name":108,"role":88,"phone":267,"phoneExt":43,"email":43},"727-849-4131",{"facility":269,"status":94,"city":270,"state":186,"zip":271,"country":98,"countryCode":99,"cosmosGeoPoint":272,"geoPoint":276,"contacts":277},"Renstar Medical Research ( Site 1012)","Ocala","34471",{"type":101,"coordinates":273},[274,275],-82.14009,29.1872,{"lat":275,"lon":274},[278],{"name":108,"role":88,"phone":279,"phoneExt":43,"email":43},"352-629-5800",{"facility":281,"status":94,"city":282,"state":186,"zip":283,"country":98,"countryCode":99,"cosmosGeoPoint":284,"geoPoint":288,"contacts":289},"Charter Research - Orlando ( Site 1051)","Orlando","32803",{"type":101,"coordinates":285},[286,287],-81.37924,28.53834,{"lat":287,"lon":286},[290],{"name":108,"role":88,"phone":291,"phoneExt":43,"email":43},"407-337-3000",{"facility":293,"status":94,"city":294,"state":186,"zip":295,"country":98,"countryCode":99,"cosmosGeoPoint":296,"geoPoint":300,"contacts":301},"Axiom Brain Health ( Site 1029)","Tampa","33609",{"type":101,"coordinates":297},[298,299],-82.45843,27.94752,{"lat":299,"lon":298},[302],{"name":108,"role":88,"phone":303,"phoneExt":43,"email":43},"813-353-9613",{"facility":305,"status":94,"city":294,"state":186,"zip":306,"country":98,"countryCode":99,"cosmosGeoPoint":307,"geoPoint":309,"contacts":310},"K2 Medical Research ( Site 1020)","33634",{"type":101,"coordinates":308},[298,299],{"lat":299,"lon":298},[311],{"name":108,"role":88,"phone":312,"phoneExt":43,"email":43},"813-800-5252",{"facility":314,"status":94,"city":315,"state":186,"zip":316,"country":98,"countryCode":99,"cosmosGeoPoint":317,"geoPoint":321,"contacts":322},"Charter Research - Lady Lake ( Site 1019)","The Villages","32162",{"type":101,"coordinates":318},[319,320],-81.95994,28.93408,{"lat":320,"lon":319},[323],{"name":108,"role":88,"phone":324,"phoneExt":43,"email":43},"352-775-1000",{"facility":326,"status":94,"city":327,"state":186,"zip":328,"country":98,"countryCode":99,"cosmosGeoPoint":329,"geoPoint":333,"contacts":334},"Conquest Research LLC ( Site 1053)","Winter Park","32789",{"type":101,"coordinates":330},[331,332],-81.33924,28.6,{"lat":332,"lon":331},[335],{"name":108,"role":88,"phone":336,"phoneExt":43,"email":43},"407-916-0060",{"facility":338,"status":94,"city":339,"state":340,"zip":341,"country":98,"countryCode":99,"cosmosGeoPoint":342,"geoPoint":346,"contacts":347},"CenExel iResearch, LLC ( Site 1015)","Decatur","Georgia","30030",{"type":101,"coordinates":343},[344,345],-84.29631,33.77483,{"lat":345,"lon":344},[348],{"name":108,"role":88,"phone":349,"phoneExt":43,"email":43},"404-537-1281",{"facility":351,"status":94,"city":352,"state":353,"zip":354,"country":98,"countryCode":99,"cosmosGeoPoint":355,"geoPoint":359,"contacts":360},"Alexian Brothers Medical Center-Neurosciences ( Site 1017)","Elk Grove Village","Illinois","60007",{"type":101,"coordinates":356},[357,358],-87.97035,42.00392,{"lat":358,"lon":357},[361],{"name":108,"role":88,"phone":362,"phoneExt":43,"email":43},"847-593-8553",{"facility":364,"status":94,"city":365,"state":366,"zip":367,"country":98,"countryCode":99,"cosmosGeoPoint":368,"geoPoint":372,"contacts":373},"Boston Center for Memory ( Site 1008)","Newton","Massachusetts","02459",{"type":101,"coordinates":369},[370,371],-71.20922,42.33704,{"lat":371,"lon":370},[374],{"name":108,"role":88,"phone":375,"phoneExt":43,"email":43},"617-699-6927",{"facility":377,"status":94,"city":378,"state":379,"zip":380,"country":98,"countryCode":99,"cosmosGeoPoint":381,"geoPoint":385,"contacts":386},"Clinical Research Professionals ( Site 1004)","Chesterfield","Missouri","63005",{"type":101,"coordinates":382},[383,384],-90.57707,38.66311,{"lat":384,"lon":383},[387],{"name":108,"role":88,"phone":388,"phoneExt":43,"email":43},"636-220-1200",{"facility":390,"status":94,"city":391,"state":392,"zip":393,"country":98,"countryCode":99,"cosmosGeoPoint":394,"geoPoint":398,"contacts":399},"The Cognitive and Research Center of New Jersey - Ridgewood ( Site 1064)","Ridgewood","New Jersey","07450",{"type":101,"coordinates":395},[396,397],-74.11653,40.97926,{"lat":397,"lon":396},[400],{"name":108,"role":88,"phone":401,"phoneExt":43,"email":43},"201-850-4622",{"facility":403,"status":94,"city":404,"state":392,"zip":405,"country":98,"countryCode":99,"cosmosGeoPoint":406,"geoPoint":410,"contacts":411},"The Cognitive and Research Center of NJ ( Site 1057)","Springfield","07081",{"type":101,"coordinates":407},[408,409],-74.31723,40.70491,{"lat":409,"lon":408},[412],{"name":108,"role":88,"phone":413,"phoneExt":43,"email":43},"973-850-4622",{"facility":415,"status":94,"city":416,"state":392,"zip":417,"country":98,"countryCode":99,"cosmosGeoPoint":418,"geoPoint":422,"contacts":423},"CenExel- AMRI ( Site 1018)","Toms River","08755",{"type":101,"coordinates":419},[420,421],-74.19792,39.95373,{"lat":421,"lon":420},[424],{"name":108,"role":88,"phone":425,"phoneExt":43,"email":43},"732-341-9500",{"facility":427,"status":94,"city":428,"state":429,"zip":430,"country":98,"countryCode":99,"cosmosGeoPoint":431,"geoPoint":435,"contacts":436},"Alzheimer Disease Research Center (ADRC) ( Site 1000)","Albany","New York","12208",{"type":101,"coordinates":432},[433,434],-73.75623,42.65258,{"lat":434,"lon":433},[437],{"name":108,"role":88,"phone":438,"phoneExt":43,"email":43},"518-426-0575",{"facility":440,"status":94,"city":441,"state":429,"zip":442,"country":98,"countryCode":99,"cosmosGeoPoint":443,"geoPoint":447,"contacts":448},"Mid Hudson Medical Research ( Site 1050)","New Windsor","12553",{"type":101,"coordinates":444},[445,446],-74.02375,41.47676,{"lat":446,"lon":445},[449],{"name":108,"role":88,"phone":450,"phoneExt":43,"email":43},"845-674-9398",{"facility":452,"status":94,"city":453,"state":429,"zip":454,"country":98,"countryCode":99,"cosmosGeoPoint":455,"geoPoint":459,"contacts":460},"Basil Clinical ( Site 1065)","Queens","11413",{"type":101,"coordinates":456},[457,458],-73.83652,40.68149,{"lat":458,"lon":457},[461],{"name":108,"role":88,"phone":462,"phoneExt":43,"email":43},"917-672-3275",{"facility":464,"status":94,"city":465,"state":466,"zip":467,"country":98,"countryCode":99,"cosmosGeoPoint":468,"geoPoint":472,"contacts":473},"AMC Research, LLC ( Site 1006)","Matthews","North Carolina","28105",{"type":101,"coordinates":469},[470,471],-80.72368,35.11681,{"lat":471,"lon":470},[474],{"name":108,"role":88,"phone":475,"phoneExt":43,"email":43},"704-364-4000",{"facility":477,"status":94,"city":478,"state":479,"zip":480,"country":98,"countryCode":99,"cosmosGeoPoint":481,"geoPoint":485,"contacts":486},"Insight Clinical Trials ( Site 1011)","Independence","Ohio","44131",{"type":101,"coordinates":482},[483,484],-81.6379,41.36866,{"lat":484,"lon":483},[487],{"name":108,"role":88,"phone":488,"phoneExt":43,"email":43},"216-245-6556",{"facility":490,"status":94,"city":491,"state":479,"zip":492,"country":98,"countryCode":99,"cosmosGeoPoint":493,"geoPoint":497,"contacts":498},"Neuro-Behavioral Clinical Research ( Site 1028)","North Canton","44720",{"type":101,"coordinates":494},[495,496],-81.40234,40.87589,{"lat":496,"lon":495},[499],{"name":108,"role":88,"phone":500,"phoneExt":43,"email":43},"330-493-1118",{"facility":502,"status":94,"city":503,"state":504,"zip":505,"country":98,"countryCode":99,"cosmosGeoPoint":506,"geoPoint":510,"contacts":511},"Flourish Research ( Site 1048)","Plymouth 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