[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632420":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":11,"locations":26,"responsibleParty":45,"collaborators":11,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":11,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":11,"enrollmentInfo":56,"targetDuration":11,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":67,"whyStopped":11,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"HW211026 dose 1","EXPERIMENTAL",null,[13],"Drug: HW211026",{"label":15,"type":10,"description":11,"interventionNames":16},"HW211026 dose 2",[13],[18,23],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"DRUG","HW211026","HW211026 ointment dose 1，applied topically on face once daily.",[9],{"type":19,"name":20,"description":24,"armGroupLabels":25,"otherNames":11},"HW211026 ointment dose 2，applied topically on face once daily.",[15],[27],{"facility":28,"status":11,"city":29,"state":11,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Shanghai Skin Disease Hospital","Shanghai","200443","China","CN",{"type":34,"coordinates":35},"Point",[36,37],121.45806,31.22222,{"lat":37,"lon":36},[40],{"name":41,"role":42,"phone":43,"phoneExt":11,"email":44},"Guolong Zhang, Doctor","CONTACT","+87 021 36803156","zglamu@163.com",{"type":46,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100632420","phase-2-a-phase-2-study-of-hw211026-100632420",false,"NCT07513454","A Phase 2 Study of HW211026","A Multicenter, Open-label, Phase II Clinical Trial to Evaluate the Efficacy and Safety of HW211026 Ointment in Patients With Actinic Keratosis.","Key Inclusion Criteria:\n\n* Aged ≥ 18 years, male or female.\n* 2 to 8 clinically typical target actinic keratosis lesions on the face.\n* Willing to avoid direct sun or ultraviolet exposure to the treatment area during the trial.\n* Fully informed about the study, voluntarily sign the informed consent form, and be able to comply with study procedures and follow-up examination requirements.\n\nKey Exclusion Criteria:\n\n* Target lesions with any of the following conditions: 1) Clinically atypical and\u002For rapidly changing actinic keratosis lesions, such as hypertrophic lesions, hyperkeratotic lesions, and\u002For cutaneous horns. 2) Maximum diameter of a single lesion \\> 2 cm. 3) Concurrent invasive squamous cell carcinoma, Bowen's disease, basal cell carcinoma or other malignant tumors. 4) Other skin diseases or skin conditions that may interfere with examination or lesion assessment.\n* Presence of incompletely healed wounds or suspected squamous cell carcinoma, basal cell carcinoma, or other malignant tumors within 5 cm of the actinic keratosis lesions.\n* Participants with other skin diseases or skin conditions that, in the investigator's judgment, may interfere with the evaluation of safety or efficacy.\n* Participants who have undergone major surgery within 3 months prior to screening, or who plan to undergo surgery during the trial, as determined by the investigator.\n* Participants who have participated in any investigational drug clinical trial and received an investigational product within 3 months prior to screening.","ALL","18 Years",{"count":57,"type":58},80,"ESTIMATED","INTERVENTIONAL",[61],"PHASE2","This is a multicenter, randomized, open-label, parallel-group, Phase II clinical trial designed to evaluate the efficacy and safety of HW211026 in adult patients with actinic keratosis.",[64],"Actinic Keratosis",[20,66],"actinic keratosis","NOT_YET_RECRUITING","2026-07-07",{"date":70,"type":71},"2026-07-09","ACTUAL",{"date":73,"type":58},"2026-07",{"date":75,"type":58},"2027-12",{"name":5,"class":6},1]