[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609143":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":28,"locations":34,"responsibleParty":908,"collaborators":11,"id":910,"slug":911,"hasResults":912,"nctId":913,"briefTitle":914,"officialTitle":915,"acronym":916,"eligibilityCriteria":917,"healthyVolunteers":912,"sex":918,"minAge":919,"maxAge":11,"enrollmentInfo":920,"targetDuration":11,"studyType":923,"phases":924,"briefSummary":927,"conditions":928,"keywords":11,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":930,"lastUpdatePostDateStruct":931,"startDateStruct":934,"completionDateStruct":936,"leadSponsor":938,"locationsCount":939},{"fullName":5,"class":6},"Kardigan, Inc.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"danicamtiv","EXPERIMENTAL",null,[13],"Drug: danicamtiv",{"label":15,"type":16,"description":11,"interventionNames":17},"placebo","PLACEBO_COMPARATOR",[18],"Drug: Placebo",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DRUG","Danicamtiv will be administrated twice daily for up to 26 weeks",[9],{"type":21,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Placebo","Placebo will be administrated twice daily for up to 26 weeks",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":11,"email":33},"Kardigan Clinical Trial Information Team","CONTACT","1-877-310-5135","clinicaltrials@kardigan.bio",[35,52,64,73,84,95,106,118,130,142,154,166,178,190,202,213,225,236,248,259,267,279,291,302,314,326,338,350,357,370,381,392,403,414,427,438,449,462,473,484,492,503,516,527,540,551,562,570,578,589,600,611,622,633,646,657,668,681,692,703,714,729,741,752,762,773,784,795,806,819,827,840,851,862,873,881,889,897],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"University of Alabama Birmingham","RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-86.80249,33.52066,{"lat":47,"lon":46},[50],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},"Kardigan Clinical Trial Team",{"facility":53,"status":37,"city":54,"state":55,"zip":56,"country":41,"countryCode":42,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Cedars Sinai","Los Angeles","California","90048",{"type":44,"coordinates":58},[59,60],-118.24368,34.05223,{"lat":60,"lon":59},[63],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":65,"status":66,"city":54,"state":55,"zip":67,"country":41,"countryCode":42,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"University of California, Los Angeles (UCLA) - David Geffen School of Medicine","NOT_YET_RECRUITING","90095",{"type":44,"coordinates":69},[59,60],{"lat":60,"lon":59},[72],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":74,"status":37,"city":75,"state":55,"zip":76,"country":41,"countryCode":42,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"University of California, San Diego (UCSD) - Medical Center","San Diego","92037",{"type":44,"coordinates":78},[79,80],-117.16472,32.71571,{"lat":80,"lon":79},[83],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":85,"status":37,"city":86,"state":55,"zip":87,"country":41,"countryCode":42,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"UCSF","San Francisco","94158",{"type":44,"coordinates":89},[90,91],-122.41942,37.77493,{"lat":91,"lon":90},[94],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":96,"status":66,"city":97,"state":55,"zip":98,"country":41,"countryCode":42,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Stanford University Medical Center","Stanford","94305",{"type":44,"coordinates":100},[101,102],-122.16608,37.42411,{"lat":102,"lon":101},[105],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":107,"status":37,"city":108,"state":109,"zip":110,"country":41,"countryCode":42,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"MedStar Washington Hospital Center","Washington D.C.","District of Columbia","20010",{"type":44,"coordinates":112},[113,114],-77.03637,38.89511,{"lat":114,"lon":113},[117],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":119,"status":37,"city":120,"state":121,"zip":122,"country":41,"countryCode":42,"cosmosGeoPoint":123,"geoPoint":127,"contacts":128},"Mayo Clinic - Jacksonville","Jacksonville","Florida","32224",{"type":44,"coordinates":124},[125,126],-81.65565,30.33218,{"lat":126,"lon":125},[129],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":131,"status":37,"city":132,"state":133,"zip":134,"country":41,"countryCode":42,"cosmosGeoPoint":135,"geoPoint":139,"contacts":140},"Northwestern University","Chicago","Illinois","60611",{"type":44,"coordinates":136},[137,138],-87.65005,41.85003,{"lat":138,"lon":137},[141],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":143,"status":37,"city":144,"state":145,"zip":146,"country":41,"countryCode":42,"cosmosGeoPoint":147,"geoPoint":151,"contacts":152},"Louisiana State University (LSU) Health Sciences Center","New Orleans","Louisiana","70112",{"type":44,"coordinates":148},[149,150],-90.07507,29.95465,{"lat":150,"lon":149},[153],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":155,"status":66,"city":156,"state":157,"zip":158,"country":41,"countryCode":42,"cosmosGeoPoint":159,"geoPoint":163,"contacts":164},"Johns Hopkins Medicine","Baltimore","Maryland","21218",{"type":44,"coordinates":160},[161,162],-76.61219,39.29038,{"lat":162,"lon":161},[165],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":167,"status":37,"city":168,"state":169,"zip":170,"country":41,"countryCode":42,"cosmosGeoPoint":171,"geoPoint":175,"contacts":176},"Brigham and Women's Hospital","Boston","Massachusetts","02115",{"type":44,"coordinates":172},[173,174],-71.05977,42.35843,{"lat":174,"lon":173},[177],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":179,"status":37,"city":180,"state":181,"zip":182,"country":41,"countryCode":42,"cosmosGeoPoint":183,"geoPoint":187,"contacts":188},"Henry Ford Health System","Detroit","Michigan","48202",{"type":44,"coordinates":184},[185,186],-83.04575,42.33143,{"lat":186,"lon":185},[189],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":191,"status":37,"city":192,"state":193,"zip":194,"country":41,"countryCode":42,"cosmosGeoPoint":195,"geoPoint":199,"contacts":200},"University of Minnesota","Minneapolis","Minnesota","55455",{"type":44,"coordinates":196},[197,198],-93.26384,44.97997,{"lat":198,"lon":197},[201],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":203,"status":37,"city":204,"state":193,"zip":205,"country":41,"countryCode":42,"cosmosGeoPoint":206,"geoPoint":210,"contacts":211},"Mayo Clinic Rochester","Rochester","55905",{"type":44,"coordinates":207},[208,209],-92.4699,44.02163,{"lat":209,"lon":208},[212],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":214,"status":66,"city":215,"state":216,"zip":217,"country":41,"countryCode":42,"cosmosGeoPoint":218,"geoPoint":222,"contacts":223},"Saint Luke's Mid America Heart Institute","Kansas City","Missouri","64111",{"type":44,"coordinates":219},[220,221],-94.57857,39.09973,{"lat":221,"lon":220},[224],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":226,"status":37,"city":227,"state":216,"zip":228,"country":41,"countryCode":42,"cosmosGeoPoint":229,"geoPoint":233,"contacts":234},"Washington University in St. Louis","St Louis","63110",{"type":44,"coordinates":230},[231,232],-90.19789,38.62727,{"lat":232,"lon":231},[235],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":237,"status":37,"city":238,"state":239,"zip":240,"country":41,"countryCode":42,"cosmosGeoPoint":241,"geoPoint":245,"contacts":246},"University of Nebraska Medical Center","Omaha","Nebraska","68106",{"type":44,"coordinates":242},[243,244],-95.94043,41.25626,{"lat":244,"lon":243},[247],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":249,"status":37,"city":250,"state":250,"zip":251,"country":41,"countryCode":42,"cosmosGeoPoint":252,"geoPoint":256,"contacts":257},"NYU Langone Health","New York","10016",{"type":44,"coordinates":253},[254,255],-74.00597,40.71427,{"lat":255,"lon":254},[258],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":260,"status":66,"city":250,"state":250,"zip":261,"country":41,"countryCode":42,"cosmosGeoPoint":262,"geoPoint":264,"contacts":265},"Columbia University Medical Center\u002F New York Presbyterian Hospital","10027",{"type":44,"coordinates":263},[254,255],{"lat":255,"lon":254},[266],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":268,"status":37,"city":269,"state":270,"zip":271,"country":41,"countryCode":42,"cosmosGeoPoint":272,"geoPoint":276,"contacts":277},"Duke University Medical Center","Durham","North Carolina","27708",{"type":44,"coordinates":273},[274,275],-78.89862,35.99403,{"lat":275,"lon":274},[278],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":280,"status":37,"city":281,"state":282,"zip":283,"country":41,"countryCode":42,"cosmosGeoPoint":284,"geoPoint":288,"contacts":289},"The Lindner Center for Research and Education at The Christ Hospital","Cincinnati","Ohio","45219",{"type":44,"coordinates":285},[286,287],-84.51439,39.12711,{"lat":287,"lon":286},[290],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":292,"status":37,"city":293,"state":282,"zip":294,"country":41,"countryCode":42,"cosmosGeoPoint":295,"geoPoint":299,"contacts":300},"The Ohio State University Wexner Medical Center","Columbus","43210",{"type":44,"coordinates":296},[297,298],-82.99879,39.96118,{"lat":298,"lon":297},[301],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":303,"status":37,"city":304,"state":305,"zip":306,"country":41,"countryCode":42,"cosmosGeoPoint":307,"geoPoint":311,"contacts":312},"Oregon Health & Science University (OHSU)","Portland","Oregon","97239",{"type":44,"coordinates":308},[309,310],-122.67621,45.52345,{"lat":310,"lon":309},[313],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":315,"status":37,"city":316,"state":317,"zip":318,"country":41,"countryCode":42,"cosmosGeoPoint":319,"geoPoint":323,"contacts":324},"University of Pennsylvania","Philadelphia","Pennsylvania","19104",{"type":44,"coordinates":320},[321,322],-75.16362,39.95238,{"lat":322,"lon":321},[325],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":327,"status":37,"city":328,"state":329,"zip":330,"country":41,"countryCode":42,"cosmosGeoPoint":331,"geoPoint":335,"contacts":336},"Vanderbilt University Medical Center","Nashville","Tennessee","37232",{"type":44,"coordinates":332},[333,334],-86.78444,36.16589,{"lat":334,"lon":333},[337],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":339,"status":37,"city":340,"state":341,"zip":342,"country":41,"countryCode":42,"cosmosGeoPoint":343,"geoPoint":347,"contacts":348},"Baylor College of Medicine","Houston","Texas","77030",{"type":44,"coordinates":344},[345,346],-95.36327,29.76328,{"lat":346,"lon":345},[349],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":351,"status":66,"city":340,"state":341,"zip":342,"country":41,"countryCode":42,"cosmosGeoPoint":352,"geoPoint":354,"contacts":355},"Houston Methodist Hospital",{"type":44,"coordinates":353},[345,346],{"lat":346,"lon":345},[356],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":358,"status":37,"city":359,"state":11,"zip":360,"country":361,"countryCode":362,"cosmosGeoPoint":363,"geoPoint":367,"contacts":368},"AZORG - Campus Moorselbaan","Aalst","9300","Belgium","BE",{"type":44,"coordinates":364},[365,366],4.0355,50.93604,{"lat":366,"lon":365},[369],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":371,"status":37,"city":372,"state":11,"zip":373,"country":361,"countryCode":362,"cosmosGeoPoint":374,"geoPoint":378,"contacts":379},"Universite Libre de Bruxelles (ULB) - Hopital Erasme","Brussels","1070",{"type":44,"coordinates":375},[376,377],4.34878,50.85045,{"lat":377,"lon":376},[380],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":382,"status":37,"city":383,"state":11,"zip":384,"country":361,"countryCode":362,"cosmosGeoPoint":385,"geoPoint":389,"contacts":390},"Universitair Ziekenhuis Antwerpen (UZA)","Edegem","2650",{"type":44,"coordinates":386},[387,388],4.44504,51.15662,{"lat":388,"lon":387},[391],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":393,"status":66,"city":394,"state":11,"zip":395,"country":361,"countryCode":362,"cosmosGeoPoint":396,"geoPoint":400,"contacts":401},"Jessa Ziekenhuis","Hasselt","3500",{"type":44,"coordinates":397},[398,399],5.33781,50.93106,{"lat":399,"lon":398},[402],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":404,"status":37,"city":405,"state":11,"zip":406,"country":361,"countryCode":362,"cosmosGeoPoint":407,"geoPoint":411,"contacts":412},"UZ Leuven","Leuven","3000",{"type":44,"coordinates":408},[409,410],4.70093,50.87959,{"lat":410,"lon":409},[413],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":415,"status":37,"city":416,"state":11,"zip":417,"country":418,"countryCode":419,"cosmosGeoPoint":420,"geoPoint":424,"contacts":425},"Aarhus University Hospital","Aarhus","8200","Denmark","DK",{"type":44,"coordinates":421},[422,423],10.21076,56.15674,{"lat":423,"lon":422},[426],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":428,"status":37,"city":429,"state":11,"zip":430,"country":418,"countryCode":419,"cosmosGeoPoint":431,"geoPoint":435,"contacts":436},"Rigshospitalet","Copenhagen","1050",{"type":44,"coordinates":432},[433,434],12.56553,55.67594,{"lat":434,"lon":433},[437],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":439,"status":37,"city":440,"state":11,"zip":441,"country":418,"countryCode":419,"cosmosGeoPoint":442,"geoPoint":446,"contacts":447},"Odense University Hospital - Odense","Odense","5000",{"type":44,"coordinates":443},[444,445],10.38831,55.39594,{"lat":445,"lon":444},[448],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":450,"status":66,"city":451,"state":11,"zip":452,"country":453,"countryCode":454,"cosmosGeoPoint":455,"geoPoint":459,"contacts":460},"CHRU de Tours - Hopital Trousseau","Chambray-lès-Tours","37170","France","FR",{"type":44,"coordinates":456},[457,458],0.70286,47.33537,{"lat":458,"lon":457},[461],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":463,"status":66,"city":464,"state":11,"zip":465,"country":453,"countryCode":454,"cosmosGeoPoint":466,"geoPoint":470,"contacts":471},"CHU de Lille - Institut Coeur Poumon","Lille","59037",{"type":44,"coordinates":467},[468,469],3.05512,50.63391,{"lat":469,"lon":468},[472],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":474,"status":37,"city":475,"state":11,"zip":476,"country":453,"countryCode":454,"cosmosGeoPoint":477,"geoPoint":481,"contacts":482},"AP-HP Hopital Pitie-Salpetriere","Paris","75013",{"type":44,"coordinates":478},[479,480],2.3488,48.85341,{"lat":480,"lon":479},[483],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":485,"status":37,"city":475,"state":11,"zip":486,"country":453,"countryCode":454,"cosmosGeoPoint":487,"geoPoint":489,"contacts":490},"AP-HP Hopital Europeen Georges Pompidou","75015",{"type":44,"coordinates":488},[479,480],{"lat":480,"lon":479},[491],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":493,"status":66,"city":494,"state":11,"zip":495,"country":453,"countryCode":454,"cosmosGeoPoint":496,"geoPoint":500,"contacts":501},"CHU Rennes - Hopital Pontchaillou","Rennes","35033",{"type":44,"coordinates":497},[498,499],-1.67431,48.11109,{"lat":499,"lon":498},[502],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":504,"status":37,"city":505,"state":11,"zip":506,"country":507,"countryCode":508,"cosmosGeoPoint":509,"geoPoint":513,"contacts":514},"Semmelweis Egyetem - Varosmajori Sziv es Ergyogyaszati Klinika","Budapest","1122","Hungary","HU",{"type":44,"coordinates":510},[511,512],19.04045,47.49835,{"lat":512,"lon":511},[515],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":517,"status":37,"city":518,"state":11,"zip":519,"country":507,"countryCode":508,"cosmosGeoPoint":520,"geoPoint":524,"contacts":525},"Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont","Szeged","6724",{"type":44,"coordinates":521},[522,523],20.14824,46.253,{"lat":523,"lon":522},[526],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":528,"status":66,"city":529,"state":11,"zip":530,"country":531,"countryCode":532,"cosmosGeoPoint":533,"geoPoint":537,"contacts":538},"Azienda Ospedaliera Universitaria Consorziale - Policlinico Bari","Bari","70124","Italy","IT",{"type":44,"coordinates":534},[535,536],16.86982,41.12066,{"lat":536,"lon":535},[539],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":541,"status":37,"city":542,"state":11,"zip":543,"country":531,"countryCode":532,"cosmosGeoPoint":544,"geoPoint":548,"contacts":549},"Azienda Ospedaliero-Universitaria Careggi","Florence","50134",{"type":44,"coordinates":545},[546,547],11.24626,43.77925,{"lat":547,"lon":546},[550],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":552,"status":66,"city":553,"state":11,"zip":554,"country":531,"countryCode":532,"cosmosGeoPoint":555,"geoPoint":559,"contacts":560},"IRCCS Ospedale San Raffaele","Milan","20132",{"type":44,"coordinates":556},[557,558],12.59836,42.78235,{"lat":558,"lon":557},[561],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":563,"status":37,"city":553,"state":11,"zip":564,"country":531,"countryCode":532,"cosmosGeoPoint":565,"geoPoint":567,"contacts":568},"Centro Cardiologico Monzino","20138",{"type":44,"coordinates":566},[557,558],{"lat":558,"lon":557},[569],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":571,"status":37,"city":553,"state":11,"zip":572,"country":531,"countryCode":532,"cosmosGeoPoint":573,"geoPoint":575,"contacts":576},"ASST Grande Ospedale Metropolitano Niguarda","20162",{"type":44,"coordinates":574},[557,558],{"lat":558,"lon":557},[577],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":579,"status":66,"city":580,"state":11,"zip":581,"country":531,"countryCode":532,"cosmosGeoPoint":582,"geoPoint":586,"contacts":587},"Azienda Ospedale - Università Padova","Padova","35128",{"type":44,"coordinates":583},[584,585],11.14261,44.38225,{"lat":585,"lon":584},[588],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":590,"status":66,"city":591,"state":11,"zip":592,"country":531,"countryCode":532,"cosmosGeoPoint":593,"geoPoint":597,"contacts":598},"Fondazione IRCCS Policlinico San Matteo","Pavia","27100",{"type":44,"coordinates":594},[595,596],9.15917,45.19205,{"lat":596,"lon":595},[599],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":601,"status":66,"city":602,"state":11,"zip":603,"country":531,"countryCode":532,"cosmosGeoPoint":604,"geoPoint":608,"contacts":609},"Ospedale Policlinico Casilino","Roma","00169",{"type":44,"coordinates":605},[606,607],11.10642,44.99364,{"lat":607,"lon":606},[610],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":612,"status":37,"city":613,"state":11,"zip":614,"country":531,"countryCode":532,"cosmosGeoPoint":615,"geoPoint":619,"contacts":620},"Istituto Clinico Humanitas","Rozzano","20089",{"type":44,"coordinates":616},[617,618],9.1559,45.38193,{"lat":618,"lon":617},[621],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":623,"status":37,"city":624,"state":11,"zip":625,"country":531,"countryCode":532,"cosmosGeoPoint":626,"geoPoint":630,"contacts":631},"Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI) - Ospedale di Cattinara","Trieste","34100",{"type":44,"coordinates":627},[628,629],13.77678,45.64953,{"lat":629,"lon":628},[632],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":634,"status":37,"city":635,"state":11,"zip":636,"country":637,"countryCode":638,"cosmosGeoPoint":639,"geoPoint":643,"contacts":644},"Amsterdam UMC - Locatie AMC","Amsterdam","1105-AZ","Netherlands","NL",{"type":44,"coordinates":640},[641,642],4.88969,52.37403,{"lat":642,"lon":641},[645],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":647,"status":37,"city":648,"state":11,"zip":649,"country":637,"countryCode":638,"cosmosGeoPoint":650,"geoPoint":654,"contacts":655},"Maastricht University Medical Center","Maastricht","6229 HX",{"type":44,"coordinates":651},[652,653],5.68889,50.84833,{"lat":653,"lon":652},[656],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":658,"status":37,"city":659,"state":11,"zip":660,"country":637,"countryCode":638,"cosmosGeoPoint":661,"geoPoint":665,"contacts":666},"Erasmus MC","Rotterdam","3015 GD",{"type":44,"coordinates":662},[663,664],4.47917,51.9225,{"lat":664,"lon":663},[667],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":669,"status":66,"city":670,"state":11,"zip":671,"country":672,"countryCode":673,"cosmosGeoPoint":674,"geoPoint":678,"contacts":679},"Uniwersyteckie Centrum Kliniczne, Gdansk","Gdansk","80-952","Poland","PL",{"type":44,"coordinates":675},[676,677],18.64912,54.35227,{"lat":677,"lon":676},[680],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":682,"status":37,"city":683,"state":11,"zip":684,"country":672,"countryCode":673,"cosmosGeoPoint":685,"geoPoint":689,"contacts":690},"Krakowski Szpital Specjalistyczny im. sw. Jana Pawla II","Krakow","31-202",{"type":44,"coordinates":686},[687,688],19.93658,50.06143,{"lat":688,"lon":687},[691],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":693,"status":37,"city":694,"state":11,"zip":695,"country":672,"countryCode":673,"cosmosGeoPoint":696,"geoPoint":700,"contacts":701},"Samodzielny Publiczny Zaklad Opieki Zdrowotnej Centralny Szpital Kliniczny Uniwersytetu Medycznego w Lodzi","Lodz","92-213",{"type":44,"coordinates":697},[698,699],19.47395,51.77058,{"lat":699,"lon":698},[702],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":704,"status":66,"city":705,"state":11,"zip":706,"country":672,"countryCode":673,"cosmosGeoPoint":707,"geoPoint":711,"contacts":712},"Narodowy Instytut Kardiologii Stefana kardynala Wyszynskiego - Panstwowy Instytut Badawczy w Warszawie","Warsaw","04-628",{"type":44,"coordinates":708},[709,710],21.01178,52.22977,{"lat":710,"lon":709},[713],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":715,"status":37,"city":716,"state":717,"zip":718,"country":719,"countryCode":720,"cosmosGeoPoint":721,"geoPoint":725,"contacts":726},"Hospital Universitario Vall d'Hebron","Horta-Guinardó","Barcelona","08035","Spain","ES",{"type":44,"coordinates":722},[723,724],2.1677,41.41849,{"lat":724,"lon":723},[727],{"name":728,"role":31,"phone":32,"phoneExt":11,"email":33},"Kardigan Clinical Trials Team",{"facility":730,"status":37,"city":731,"state":732,"zip":733,"country":719,"countryCode":720,"cosmosGeoPoint":734,"geoPoint":738,"contacts":739},"Hospital Universitario Puerta de Hierro","Majadahonda","Madrid","20222",{"type":44,"coordinates":735},[736,737],-3.87182,40.47353,{"lat":737,"lon":736},[740],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":742,"status":37,"city":743,"state":11,"zip":744,"country":719,"countryCode":720,"cosmosGeoPoint":745,"geoPoint":749,"contacts":750},"Hospital Universitario de A Coruña","A Coruña","15006",{"type":44,"coordinates":746},[747,748],-8.396,43.37135,{"lat":748,"lon":747},[751],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":753,"status":37,"city":717,"state":11,"zip":754,"country":719,"countryCode":720,"cosmosGeoPoint":755,"geoPoint":759,"contacts":760},"Hospital Universitari de Bellvitge","08907",{"type":44,"coordinates":756},[757,758],2.15899,41.38879,{"lat":758,"lon":757},[761],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":763,"status":37,"city":764,"state":11,"zip":765,"country":719,"countryCode":720,"cosmosGeoPoint":766,"geoPoint":770,"contacts":771},"Hospital Universitario Virgen de la Victoria","Málaga","29001",{"type":44,"coordinates":767},[768,769],-4.42034,36.72016,{"lat":769,"lon":768},[772],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":774,"status":37,"city":775,"state":11,"zip":776,"country":719,"countryCode":720,"cosmosGeoPoint":777,"geoPoint":781,"contacts":782},"Hospital Clinico Universitario Virgen de la Arrixaca","Murcia","30120 El Palmar,",{"type":44,"coordinates":778},[779,780],-1.13004,37.98704,{"lat":780,"lon":779},[783],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":785,"status":37,"city":786,"state":11,"zip":787,"country":719,"countryCode":720,"cosmosGeoPoint":788,"geoPoint":792,"contacts":793},"Hospital Universitario Son Llatzer","Palma de Mallorca","7198",{"type":44,"coordinates":789},[790,791],2.65024,39.56939,{"lat":791,"lon":790},[794],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":796,"status":37,"city":797,"state":11,"zip":798,"country":719,"countryCode":720,"cosmosGeoPoint":799,"geoPoint":803,"contacts":804},"Hospital Universitario Virgen del Rocio","Seville","41013",{"type":44,"coordinates":800},[801,802],-5.97317,37.38283,{"lat":802,"lon":801},[805],{"name":728,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":807,"status":37,"city":808,"state":11,"zip":809,"country":810,"countryCode":811,"cosmosGeoPoint":812,"geoPoint":816,"contacts":817},"Sodersjukhuset AB","Stockholm","11883","Sweden","SE",{"type":44,"coordinates":813},[814,815],18.06871,59.32938,{"lat":815,"lon":814},[818],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":820,"status":66,"city":808,"state":11,"zip":821,"country":810,"countryCode":811,"cosmosGeoPoint":822,"geoPoint":824,"contacts":825},"Danderyds sjukhus","182 88",{"type":44,"coordinates":823},[814,815],{"lat":815,"lon":814},[826],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":828,"status":37,"city":829,"state":11,"zip":830,"country":831,"countryCode":832,"cosmosGeoPoint":833,"geoPoint":837,"contacts":838},"University Hospitals Bristol NHS Foundation Trust","Bristol","BS1 3NU","United Kingdom","UK",{"type":44,"coordinates":834},[835,836],-2.59665,51.45523,{"lat":836,"lon":835},[839],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":841,"status":37,"city":842,"state":11,"zip":843,"country":831,"countryCode":832,"cosmosGeoPoint":844,"geoPoint":848,"contacts":849},"NHS Greater Glasgow and Clyde","Glasgow","G12 0YN",{"type":44,"coordinates":845},[846,847],-4.25763,55.86515,{"lat":847,"lon":846},[850],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":852,"status":37,"city":853,"state":11,"zip":854,"country":831,"countryCode":832,"cosmosGeoPoint":855,"geoPoint":859,"contacts":860},"Glenfield Hospital","Leicester","LE3 9QP",{"type":44,"coordinates":856},[857,858],-1.13169,52.6386,{"lat":858,"lon":857},[861],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":863,"status":37,"city":864,"state":11,"zip":865,"country":831,"countryCode":832,"cosmosGeoPoint":866,"geoPoint":870,"contacts":871},"St. Bartholomew's Hospital","London","EC1A",{"type":44,"coordinates":867},[868,869],-0.12574,51.50853,{"lat":869,"lon":868},[872],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":874,"status":37,"city":864,"state":11,"zip":875,"country":831,"countryCode":832,"cosmosGeoPoint":876,"geoPoint":878,"contacts":879},"St George's Hospital","SW17 0QT",{"type":44,"coordinates":877},[868,869],{"lat":869,"lon":868},[880],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":882,"status":37,"city":864,"state":11,"zip":883,"country":831,"countryCode":832,"cosmosGeoPoint":884,"geoPoint":886,"contacts":887},"Royal Brompton Hospital","SW3 6NP",{"type":44,"coordinates":885},[868,869],{"lat":869,"lon":868},[888],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":890,"status":37,"city":864,"state":11,"zip":891,"country":831,"countryCode":832,"cosmosGeoPoint":892,"geoPoint":894,"contacts":895},"Hammersmith Hospital, Imperial College of London","W12 0HS",{"type":44,"coordinates":893},[868,869],{"lat":869,"lon":868},[896],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"facility":898,"status":37,"city":899,"state":11,"zip":900,"country":831,"countryCode":832,"cosmosGeoPoint":901,"geoPoint":905,"contacts":906},"Cardiovascular Clinical Research Facility (CCRF)","Oxford","OX3 9DU",{"type":44,"coordinates":902},[903,904],-1.25596,51.75222,{"lat":904,"lon":903},[907],{"name":51,"role":31,"phone":32,"phoneExt":11,"email":33},{"type":909,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100609143","phase-2-a-study-of-the-efficacy-and-safety-of-danicamtiv-in-participants-with-symptomatic-genetic-and-familial-dilated-cardiomyopathy-100609143",false,"NCT07210723","A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy","A Phase 2b\u002F3, Adaptive, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy","KINSHIP-DCM","Key Inclusion Criteria:\n\n1. Has a diagnosis of DCM due to probable disease-causing variants of MYH7, TTN, or other identified genetic DCM variants, or with familial DCM\n2. Has New York Heart Association (NYHA) Class II-IV at Screening with stable symptoms for ≥1 month.\n3. Has at least mild left ventricular enlargement (LVE) and has adequate acoustic windows to enable accurate TTEs according to the Echocardiography Core Laboratory.\n4. Has a LVEF of ≤45%.\n5. Is on stable doses of maximally tolerated standard-of-care heart failure (HF) therapies reflecting current guidelines for at least 4 weeks prior to the first visit.\n6. Has DCM not attributed to substance abuse, amyloidosis, sarcoidosis, or any other secondary form of cardiomyopathy per the Investigator.\n7. Can perform an upright cardiopulmonary exercise training (CPET) with a peak oxygen uptake (pV̇O2) of 80% or less of predicted for a healthy individual and respiratory exchange ratio (RER) of ≥1.05\n\nKey Exclusion Criteria:\n\n1. Has heart failure with reduced ejection (HFrEF) caused primarily by ischemic heart disease, chronic valvulopathy, or another condition, as determined by the Investigator.\n2. Recent (\\\u003C90 days) clinically significant cardiac events, including acute coronary syndrome, hemodynamically significant epicardial coronary disease (per Investigator), coronary revascularization (percutaneous coronary intervention \\[PCI\\] or coronary artery bypass graft \\[CABG\\]), or hospitalization for heart failure\u002Fintravenous (IV) diuretic use.\n3. Presence of disqualifying cardiac rhythms that might interfere with reliable echocardiographic measurements of left ventricle (LV) function, as determined by the Investigator including: (a) inadequately rate-controlled atrial fibrillation, (b) ectopic beats (atrial, junctional or ventricular) of sufficient frequency (e.g. \\> 10% of total beats) that the participant's cardiac rhythm is irregular potentially interfering with reliable echocardiographic measurements of LV function.\n4. Unstable or untreated severe ventricular arrythmia (eg, ventricular tachycardia or ventricular fibrillation).\n5. History of malignancy of any type within 5 years prior to Screening\n6. Severe renal insufficiency (defined at the time of Screening as current estimated glomerular filtration rate \\[eGFR\\] \\\u003C15 mL\u002Fmin\u002F1.73m2 by simplified Modification of Diet in Renal Disease equation \\[sMDRD\\]).\n7. History or evidence of any other clinically significant disorder, condition, or disease that, in the opinion of the Investigator or Sponsor, would pose a risk to participant safety or interfere with the study evaluation\n8. History of heart transplantation or anticipated heart transplantation in the next 6 months.\n9. Ongoing or anticipated advanced cardiac interventions, including chronic IV inotropic therapy, planned cardiac resynchronization therapy (CRT) or major surgery, or current\u002Fanticipated ventricular assist device placement within 6 months\n10. Clinically significant laboratory abnormalities at Screening","ALL","18 Years",{"count":921,"type":922},332,"ESTIMATED","INTERVENTIONAL",[925,926],"PHASE2","PHASE3","The Sponsor is studying an investigational medication called danicamtiv to determine if it can help people with genetic and familial dilated cardiomyopathy (DCM). Investigational means that the safety and effectiveness of danicamtiv have not been established. Currently, there are no approved drugs that are designed specifically to treat genetic or familial DCM.\n\nThe purpose of this study is to evaluate how well danicamtiv works compared to a placebo (sugar pill that looks like danicamtiv pill but does not contain any danicamtiv) and see how safe it is for people with genetic and familial DCM. In DCM, the heart muscle weakens and enlarges, making it harder for the heart to pump blood; this can happen for different reasons. Some people have DCM because of a change in a gene (called genetic DCM). Others may have DCM that runs in their family, even if no specific gene change is found (called familial DCM).\n\nThe main goals of the study are:\n\n* To assess the effect of danicamtiv on cardiac function using echocardiogram.\n* To evaluate the impact of danicamtiv on exercise capacity\n* To evaluate the safety and tolerability of danicamtiv\n\nParticipants will:\n\n* Take danicamtiv or placebo every day for approximately 6 months\n* Visit the clinic about 12 times for initial evaluation, checkups, tests and follow up",[929],"Symptomatic Genetic Dilated Cardiomyopathy","2026-07-31",{"date":932,"type":933},"2026-08-04","ACTUAL",{"date":935,"type":933},"2026-02-13",{"date":937,"type":922},"2028-01",{"name":5,"class":6},78]