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Meets criteria for psychosis in accordance with the International Psychogeriatric Association (IPA) provisional consensus definition at Screening and Baseline;\n4. Scoring ≥ 2 on any item of the BEHAVE-AD Part A. Paranoid and Delusional Ideation item and\u002For Part B. Hallucinations item (ie, psychosis subscale) at Screening and Baseline;\n5. CGI-S score ≥ 4 at Screening and Baseline;\n6. Mini-Mental State Examination, 2nd Edition™: Standard Version (MMSE-2®:SV) score of 6 to 24 (inclusive) at Screening with sufficient verbal ability to understand and answer questions and comply with procedures;\n7. Has a designated caregiver (eg, relative, housemate, close personal friend, or professional caregiver);\n\nExclusion Criteria:\n\n1. Psychotic symptoms that are primarily attributable to delirium, substance abuse, or another general-medical condition (eg, hypothyroidism) or has been diagnosed with one or more of the following psychiatric conditions:\n\n   1. Schizophrenia, schizoaffective disorder, or other psychotic disorder that is not related to Alzheimer's dementia;\n   2. Bipolar disorder;\n2. Risk for suicidal behavior during the course of their participation in the study or is considered to be an imminent danger to themselves or others, in the opinion of the investigator, and\u002For as assessed by C-SSRS; or the patient has had 1 or more suicide attempts within 2 years prior to Screening;\n3. The patient is unable or unwilling to discontinue other drugs with known psychotropic properties or any non-psychotropic drugs with known or potentially significant central nervous system effects, as reviewed by the Sponsor or designee,\n4. The patient is hospitalized or receiving skilled nursing care for any medical condition other than dementia\n5. The patient is bedridden or has any significant medical condition that is unstable and would either:\n\n   1. Place the patient at undue risk from study drug or undergoing study procedures; or\n   2. Interfere with the interpretation of safety or efficacy evaluations performed during the course of the study;\n6. The patient is in hospice or end-of-life care;","ALL","55 Years",{"count":613,"type":614},370,"ESTIMATED","INTERVENTIONAL",[617],"PHASE2","This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled, flexible-dose study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo in the treatment of psychosis in patients with AD.",[620],"Psychosis Associated With Alzheimer's Disease","2026-07-30",{"date":623,"type":624},"2026-07-31","ACTUAL",{"date":626,"type":624},"2024-08-15",{"date":628,"type":614},"2028-12-29",{"name":5,"class":6},65]