[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591118":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":211,"collaborators":30,"id":213,"slug":214,"hasResults":215,"nctId":216,"briefTitle":217,"officialTitle":218,"acronym":30,"eligibilityCriteria":219,"healthyVolunteers":215,"sex":220,"minAge":221,"maxAge":222,"enrollmentInfo":223,"targetDuration":30,"studyType":226,"phases":227,"briefSummary":230,"conditions":231,"keywords":233,"overallStatus":44,"whyStopped":30,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":248},{"fullName":5,"class":6},"Biohaven Pharmaceuticals, Inc.","INDUSTRY",[8,16,19],{"label":9,"type":10,"description":11,"interventionNames":12},"BHV-8000 10 mg","EXPERIMENTAL","Double-blind (DB) Phase (Randomization through Week 48): Participants will receive blinded IP.\n\nOpen-label Phase: Participants will receive BHV-8000.",[13,14,15],"Drug: BHV-8000 10mg","Drug: BHV-8000 20 mg","Drug: Placebo",{"label":17,"type":10,"description":11,"interventionNames":18},"BHV-8000 20 mg",[13,14,15],{"label":20,"type":21,"description":22,"interventionNames":23},"Placebo","PLACEBO_COMPARATOR","Double-blind (DB) Phase (Randomization through Week 48): Participants will receive blinded IP (matching placebo).\n\nOpen-label Phase: Participants will receive BHV-8000.",[13,14,15],[25,31,33],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","BHV-8000 10mg","taken orally",[9,17,20],null,{"type":26,"name":17,"description":28,"armGroupLabels":32,"otherNames":30},[9,17,20],{"type":26,"name":20,"description":28,"armGroupLabels":34,"otherNames":30},[9,17,20],[36],{"name":37,"role":38,"phone":39,"phoneExt":30,"email":40},"Chief Medical Officer","CONTACT","203-404-0410","clinicaltrials@biohavenpharma.com",[42,56,66,76,85,95,104,113,123,133,143,153,163,171,181,191,201],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":30},"Site-049","RECRUITING","Birmingham","Alabama","35294","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-86.80249,33.52066,{"lat":54,"lon":53},{"facility":57,"status":44,"city":58,"state":59,"zip":60,"country":48,"countryCode":49,"cosmosGeoPoint":61,"geoPoint":65,"contacts":30},"Site-041","Los Angeles","California","90033",{"type":51,"coordinates":62},[63,64],-118.24368,34.05223,{"lat":64,"lon":63},{"facility":67,"status":44,"city":68,"state":69,"zip":70,"country":48,"countryCode":49,"cosmosGeoPoint":71,"geoPoint":75,"contacts":30},"Site-031","Farmington","Connecticut","06030",{"type":51,"coordinates":72},[73,74],-72.83204,41.71982,{"lat":74,"lon":73},{"facility":77,"status":44,"city":78,"state":69,"zip":79,"country":48,"countryCode":49,"cosmosGeoPoint":80,"geoPoint":84,"contacts":30},"Site-028","New Haven","06510",{"type":51,"coordinates":81},[82,83],-72.92816,41.30815,{"lat":83,"lon":82},{"facility":86,"status":44,"city":87,"state":88,"zip":89,"country":48,"countryCode":49,"cosmosGeoPoint":90,"geoPoint":94,"contacts":30},"Site-038","Atlantis","Florida","33462",{"type":51,"coordinates":91},[92,93],-80.10088,26.5909,{"lat":93,"lon":92},{"facility":96,"status":44,"city":97,"state":88,"zip":98,"country":48,"countryCode":49,"cosmosGeoPoint":99,"geoPoint":103,"contacts":30},"Site-017","Boca Raton","33486",{"type":51,"coordinates":100},[101,102],-80.0831,26.35869,{"lat":102,"lon":101},{"facility":105,"status":44,"city":106,"state":88,"zip":107,"country":48,"countryCode":49,"cosmosGeoPoint":108,"geoPoint":112,"contacts":30},"Site-051","Maitland","32751",{"type":51,"coordinates":109},[110,111],-81.36312,28.62778,{"lat":111,"lon":110},{"facility":114,"status":44,"city":115,"state":116,"zip":117,"country":48,"countryCode":49,"cosmosGeoPoint":118,"geoPoint":122,"contacts":30},"Site-027","Chicago","Illinois","60611",{"type":51,"coordinates":119},[120,121],-87.65005,41.85003,{"lat":121,"lon":120},{"facility":124,"status":44,"city":125,"state":126,"zip":127,"country":48,"countryCode":49,"cosmosGeoPoint":128,"geoPoint":132,"contacts":30},"Site-071","Boston","Massachusetts","02114",{"type":51,"coordinates":129},[130,131],-71.05977,42.35843,{"lat":131,"lon":130},{"facility":134,"status":44,"city":135,"state":136,"zip":137,"country":48,"countryCode":49,"cosmosGeoPoint":138,"geoPoint":142,"contacts":30},"Site-015","Farmington Hills","Michigan","48334",{"type":51,"coordinates":139},[140,141],-83.37716,42.48531,{"lat":141,"lon":140},{"facility":144,"status":44,"city":145,"state":146,"zip":147,"country":48,"countryCode":49,"cosmosGeoPoint":148,"geoPoint":152,"contacts":30},"Site-044","Chesterfield","Missouri","63005",{"type":51,"coordinates":149},[150,151],-90.57707,38.66311,{"lat":151,"lon":150},{"facility":154,"status":44,"city":155,"state":156,"zip":157,"country":48,"countryCode":49,"cosmosGeoPoint":158,"geoPoint":162,"contacts":30},"Site-006","Albany","New York","12208",{"type":51,"coordinates":159},[160,161],-73.75623,42.65258,{"lat":161,"lon":160},{"facility":164,"status":44,"city":156,"state":156,"zip":165,"country":48,"countryCode":49,"cosmosGeoPoint":166,"geoPoint":170,"contacts":30},"Site-005","10021",{"type":51,"coordinates":167},[168,169],-74.00597,40.71427,{"lat":169,"lon":168},{"facility":172,"status":44,"city":173,"state":174,"zip":175,"country":48,"countryCode":49,"cosmosGeoPoint":176,"geoPoint":180,"contacts":30},"Site-091","Portland","Oregon","97210",{"type":51,"coordinates":177},[178,179],-122.67621,45.52345,{"lat":179,"lon":178},{"facility":182,"status":44,"city":183,"state":184,"zip":185,"country":48,"countryCode":49,"cosmosGeoPoint":186,"geoPoint":190,"contacts":30},"Site-043","Round Rock","Texas","78681",{"type":51,"coordinates":187},[188,189],-97.6789,30.50826,{"lat":189,"lon":188},{"facility":192,"status":44,"city":193,"state":194,"zip":195,"country":48,"countryCode":49,"cosmosGeoPoint":196,"geoPoint":200,"contacts":30},"Site-074","Newport News","Virginia","23601",{"type":51,"coordinates":197},[198,199],-76.42975,36.98038,{"lat":199,"lon":198},{"facility":202,"status":44,"city":203,"state":204,"zip":205,"country":48,"countryCode":49,"cosmosGeoPoint":206,"geoPoint":210,"contacts":30},"Site-007","Bellevue","Washington","98007",{"type":51,"coordinates":207},[208,209],-122.20068,47.61038,{"lat":209,"lon":208},{"type":212,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100591118","phase-2-a-study-to-determine-if-bhv-8000-is-effective-safe-and-tolerable-as-a-treatment-for-adults-living-with-early-parkinsons-disease-100591118",false,"NCT06976268","A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease","A Phase 2\u002F3, Double-Blind, Placebo-Controlled Study of BHV-8000 in Participants With Early Parkinson's Disease","Key Inclusion Criteria:\n\n* Male or female participants 40 to 80 years of age, inclusive, at the time of informed consent.\n* Meet the diagnostic criteria for \"Probable PD\" as assessed on the Movement Disorder Society (MDS) Clinical Diagnostic Criteria for PD as assessed by the Investigator.\n* Have a clinician-documented diagnosis of idiopathic PD with an onset within 2 years of the Screening Visit\n\nKey Exclusion Criteria:\n\n* Medical history indicating a Parkinsonian syndrome other than idiopathic PD, including, but not limited to, progressive supranuclear gaze palsy, multiple system atrophy, drug-induced Parkinsonism, essential tremor, or primary dystonia.\n* Diagnosis of clinically significant central nervous system (CNS) disease other than PD.\n* Participants who are current smokers (defined as smoking \\[in any form, e.g., tobacco smoke, electronic cigarettes, etc.\\] )\n* Treatment with PD medication(s)\n* Any other condition(s) that may compromise participant safety, interfere with study conduct, or jeopardize the potential proper interpretation of study results, in the opinion of the investigator.","ALL","40 Years","80 Years",{"count":224,"type":225},550,"ESTIMATED","INTERVENTIONAL",[228,229],"PHASE2","PHASE3","A study to determine if BHV-8000 is efficacious, safe and tolerable in adults diagnosed with early Parkinson's disease. The study will consist of a 48-week double-blind treatment phase followed by a 48-week open-label phase.",[232],"Parkinson Disease",[234,235,236,237],"Early Parkinson's Disease","Parkinson's Disease","Early stage Parkinson's Disease","treatment naiive early Parkinson's Disease","2026-08-17",{"date":240,"type":241},"2026-08-19","ACTUAL",{"date":243,"type":241},"2025-05-28",{"date":245,"type":225},"2028-09",{"name":247,"class":6},"Biohaven Therapeutics Ltd.",17]