[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616321":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":34,"centralContacts":39,"locations":45,"responsibleParty":471,"collaborators":34,"id":473,"slug":474,"hasResults":475,"nctId":476,"briefTitle":477,"officialTitle":478,"acronym":34,"eligibilityCriteria":479,"healthyVolunteers":475,"sex":480,"minAge":481,"maxAge":482,"enrollmentInfo":483,"targetDuration":34,"studyType":486,"phases":487,"briefSummary":489,"conditions":490,"keywords":492,"overallStatus":48,"whyStopped":34,"lastUpdateSubmitDate":499,"lastUpdatePostDateStruct":500,"startDateStruct":503,"completionDateStruct":505,"leadSponsor":507,"locationsCount":508},{"fullName":5,"class":6},"Vima Therapeutics","INDUSTRY",[8,14,20,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Segmental\u002Fmultifocal Active","ACTIVE_COMPARATOR","Segmental\u002FMultifocal isolated dystonia (enrolling participants with at least two body parts affected receiving active n\\~40",[13],"Drug: VIM0423",{"label":15,"type":16,"description":17,"interventionNames":18},"Segmental\u002Fmultifocal Placebo","PLACEBO_COMPARATOR","Segmental\u002FMultifocal isolated dystonia (enrolling participants with at least two body parts affected) receiving placebo n\\~40",[19],"Drug: VIM0423 Placebo",{"label":21,"type":10,"description":22,"interventionNames":23},"Generalized Active","Generalized isolated dystonia (enrolling participants with more than two body parts affected) receiving active n\\~10",[13],{"label":25,"type":16,"description":26,"interventionNames":27},"Generalized Placebo","Generalized isolated dystonia (enrolling participants with more than two body parts affected) receiving placebo n\\~10",[19],[29,35],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DRUG","VIM0423","VIM0423 is a combination drug product containing two active ingredients (VMA-1001 and VMA-1002)",[21,9],null,{"type":30,"name":36,"description":37,"armGroupLabels":38,"otherNames":34},"VIM0423 Placebo","Matching VIM0423 placebo product containing no active ingredient",[25,15],[40],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":44},"Study Director","CONTACT","617-430-7027","Clinicaltrials@vimatx.com",[46,63,75,83,94,106,118,130,142,153,164,176,188,200,212,223,235,247,258,270,282,293,301,312,324,336,348,360,372,384,395,407,418,429,436,448,460],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Vima Site #033","RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-86.80249,33.52066,{"lat":58,"lon":57},[61],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},"clinicaltrials@vimatx.com",{"facility":64,"status":48,"city":65,"state":66,"zip":67,"country":52,"countryCode":53,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Vima Site #039","Scottsdale","Arizona","85251",{"type":55,"coordinates":69},[70,71],-111.89903,33.50921,{"lat":71,"lon":70},[74],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":76,"status":48,"city":65,"state":66,"zip":77,"country":52,"countryCode":53,"cosmosGeoPoint":78,"geoPoint":80,"contacts":81},"Vima Site #004","85258",{"type":55,"coordinates":79},[70,71],{"lat":71,"lon":70},[82],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":84,"status":48,"city":85,"state":66,"zip":86,"country":52,"countryCode":53,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Vima Site #028","Sun City","85351",{"type":55,"coordinates":88},[89,90],-112.27182,33.59754,{"lat":90,"lon":89},[93],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":95,"status":48,"city":96,"state":97,"zip":98,"country":52,"countryCode":53,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Vima Site #042","Irvine","California","92614",{"type":55,"coordinates":100},[101,102],-117.82311,33.66946,{"lat":102,"lon":101},[105],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":107,"status":108,"city":109,"state":97,"zip":110,"country":52,"countryCode":53,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"Vima Site #030","NOT_YET_RECRUITING","Los Angeles","90048",{"type":55,"coordinates":112},[113,114],-118.24368,34.05223,{"lat":114,"lon":113},[117],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":119,"status":48,"city":120,"state":121,"zip":122,"country":52,"countryCode":53,"cosmosGeoPoint":123,"geoPoint":127,"contacts":128},"Vima Site #019","Denver","Colorado","80113",{"type":55,"coordinates":124},[125,126],-104.9847,39.73915,{"lat":126,"lon":125},[129],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":131,"status":48,"city":132,"state":133,"zip":134,"country":52,"countryCode":53,"cosmosGeoPoint":135,"geoPoint":139,"contacts":140},"Vima Site #009","Gainesville","Florida","32608",{"type":55,"coordinates":136},[137,138],-82.32483,29.65163,{"lat":138,"lon":137},[141],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":143,"status":48,"city":144,"state":133,"zip":145,"country":52,"countryCode":53,"cosmosGeoPoint":146,"geoPoint":150,"contacts":151},"Vima Site #008","Miami","33176",{"type":55,"coordinates":147},[148,149],-80.19366,25.77427,{"lat":149,"lon":148},[152],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":154,"status":48,"city":155,"state":133,"zip":156,"country":52,"countryCode":53,"cosmosGeoPoint":157,"geoPoint":161,"contacts":162},"Vima Site #031","Orlando","32825",{"type":55,"coordinates":158},[159,160],-81.37924,28.53834,{"lat":160,"lon":159},[163],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":165,"status":48,"city":166,"state":167,"zip":168,"country":52,"countryCode":53,"cosmosGeoPoint":169,"geoPoint":173,"contacts":174},"Vima Site #005","Atlanta","Georgia","30329",{"type":55,"coordinates":170},[171,172],-84.38798,33.749,{"lat":172,"lon":171},[175],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":177,"status":48,"city":178,"state":179,"zip":180,"country":52,"countryCode":53,"cosmosGeoPoint":181,"geoPoint":185,"contacts":186},"Vima Site #027","Chicago","Illinois","60611",{"type":55,"coordinates":182},[183,184],-87.65005,41.85003,{"lat":184,"lon":183},[187],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":189,"status":48,"city":190,"state":191,"zip":192,"country":52,"countryCode":53,"cosmosGeoPoint":193,"geoPoint":197,"contacts":198},"Vima Site #041","Overland Park","Kansas","66211",{"type":55,"coordinates":194},[195,196],-94.67079,38.98223,{"lat":196,"lon":195},[199],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":201,"status":48,"city":202,"state":203,"zip":204,"country":52,"countryCode":53,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"Vima Site #043","Baltimore","Maryland","21237",{"type":55,"coordinates":206},[207,208],-76.61219,39.29038,{"lat":208,"lon":207},[211],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":213,"status":48,"city":214,"state":203,"zip":215,"country":52,"countryCode":53,"cosmosGeoPoint":216,"geoPoint":220,"contacts":221},"Vima Site #007","Olney","20832",{"type":55,"coordinates":217},[218,219],-77.06692,39.15316,{"lat":219,"lon":218},[222],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":224,"status":48,"city":225,"state":226,"zip":227,"country":52,"countryCode":53,"cosmosGeoPoint":228,"geoPoint":232,"contacts":233},"Vima Site #032","Boston","Massachusetts","02215",{"type":55,"coordinates":229},[230,231],-71.05977,42.35843,{"lat":231,"lon":230},[234],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":236,"status":48,"city":237,"state":238,"zip":239,"country":52,"countryCode":53,"cosmosGeoPoint":240,"geoPoint":244,"contacts":245},"Vima Site #037","East Lansing","Michigan","48824",{"type":55,"coordinates":241},[242,243],-84.48387,42.73698,{"lat":243,"lon":242},[246],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":248,"status":48,"city":249,"state":238,"zip":250,"country":52,"countryCode":53,"cosmosGeoPoint":251,"geoPoint":255,"contacts":256},"Vima Site #002","Farmington Hills","48334",{"type":55,"coordinates":252},[253,254],-83.37716,42.48531,{"lat":254,"lon":253},[257],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":259,"status":48,"city":260,"state":261,"zip":262,"country":52,"countryCode":53,"cosmosGeoPoint":263,"geoPoint":267,"contacts":268},"Vima Site #038","St Louis","Missouri","63110",{"type":55,"coordinates":264},[265,266],-90.19789,38.62727,{"lat":266,"lon":265},[269],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":271,"status":48,"city":272,"state":273,"zip":274,"country":52,"countryCode":53,"cosmosGeoPoint":275,"geoPoint":279,"contacts":280},"Vima Site #014","Albuquerque","New Mexico","87106",{"type":55,"coordinates":276},[277,278],-106.65114,35.08449,{"lat":278,"lon":277},[281],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":283,"status":48,"city":284,"state":284,"zip":285,"country":52,"countryCode":53,"cosmosGeoPoint":286,"geoPoint":290,"contacts":291},"Vima Site #018","New York","10019",{"type":55,"coordinates":287},[288,289],-74.00597,40.71427,{"lat":289,"lon":288},[292],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":294,"status":48,"city":284,"state":284,"zip":295,"country":52,"countryCode":53,"cosmosGeoPoint":296,"geoPoint":298,"contacts":299},"Vima Site #024","10021",{"type":55,"coordinates":297},[288,289],{"lat":289,"lon":288},[300],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":302,"status":48,"city":303,"state":284,"zip":304,"country":52,"countryCode":53,"cosmosGeoPoint":305,"geoPoint":309,"contacts":310},"Vima Site #036","Rochester","14618",{"type":55,"coordinates":306},[307,308],-77.61556,43.15478,{"lat":308,"lon":307},[311],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":313,"status":48,"city":314,"state":315,"zip":316,"country":52,"countryCode":53,"cosmosGeoPoint":317,"geoPoint":321,"contacts":322},"Vima Site #040","Fayetteville","North Carolina","28304",{"type":55,"coordinates":318},[319,320],-78.87836,35.05266,{"lat":320,"lon":319},[323],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":325,"status":48,"city":326,"state":327,"zip":328,"country":52,"countryCode":53,"cosmosGeoPoint":329,"geoPoint":333,"contacts":334},"Vima Site #035","Cincinnati","Ohio","45212",{"type":55,"coordinates":330},[331,332],-84.51439,39.12711,{"lat":332,"lon":331},[335],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":337,"status":108,"city":338,"state":339,"zip":340,"country":52,"countryCode":53,"cosmosGeoPoint":341,"geoPoint":345,"contacts":346},"Vima Site #029","Portland","Oregon","97239",{"type":55,"coordinates":342},[343,344],-122.67621,45.52345,{"lat":344,"lon":343},[347],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":349,"status":48,"city":350,"state":351,"zip":352,"country":52,"countryCode":53,"cosmosGeoPoint":353,"geoPoint":357,"contacts":358},"Vima Site #020","Philadelphia","Pennsylvania","19107",{"type":55,"coordinates":354},[355,356],-75.16362,39.95238,{"lat":356,"lon":355},[359],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":361,"status":48,"city":362,"state":363,"zip":364,"country":52,"countryCode":53,"cosmosGeoPoint":365,"geoPoint":369,"contacts":370},"Vima Site #021","Charleston","South Carolina","29425",{"type":55,"coordinates":366},[367,368],-79.93275,32.77632,{"lat":368,"lon":367},[371],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":373,"status":48,"city":374,"state":375,"zip":376,"country":52,"countryCode":53,"cosmosGeoPoint":377,"geoPoint":381,"contacts":382},"Vima Site #016","Memphis","Tennessee","38157",{"type":55,"coordinates":378},[379,380],-90.04898,35.14953,{"lat":380,"lon":379},[383],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":385,"status":48,"city":386,"state":375,"zip":387,"country":52,"countryCode":53,"cosmosGeoPoint":388,"geoPoint":392,"contacts":393},"Vima Site #006","Nashville","37232",{"type":55,"coordinates":389},[390,391],-86.78444,36.16589,{"lat":391,"lon":390},[394],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":396,"status":108,"city":397,"state":398,"zip":399,"country":52,"countryCode":53,"cosmosGeoPoint":400,"geoPoint":404,"contacts":405},"Vima Site #025","Dallas","Texas","75390",{"type":55,"coordinates":401},[402,403],-96.80667,32.78306,{"lat":403,"lon":402},[406],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":408,"status":48,"city":409,"state":398,"zip":410,"country":52,"countryCode":53,"cosmosGeoPoint":411,"geoPoint":415,"contacts":416},"Vima Site #026","Georgetown","78628",{"type":55,"coordinates":412},[413,414],-97.67723,30.63269,{"lat":414,"lon":413},[417],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":419,"status":48,"city":420,"state":398,"zip":421,"country":52,"countryCode":53,"cosmosGeoPoint":422,"geoPoint":426,"contacts":427},"Vima Site #012","Houston","77030",{"type":55,"coordinates":423},[424,425],-95.36327,29.76328,{"lat":425,"lon":424},[428],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":430,"status":108,"city":420,"state":398,"zip":421,"country":52,"countryCode":53,"cosmosGeoPoint":431,"geoPoint":433,"contacts":434},"Vima Site #013",{"type":55,"coordinates":432},[424,425],{"lat":425,"lon":424},[435],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":437,"status":48,"city":438,"state":439,"zip":440,"country":52,"countryCode":53,"cosmosGeoPoint":441,"geoPoint":445,"contacts":446},"Vima Site #011","Richmond","Virginia","23233",{"type":55,"coordinates":442},[443,444],-77.46026,37.55376,{"lat":444,"lon":443},[447],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":449,"status":48,"city":450,"state":451,"zip":452,"country":52,"countryCode":53,"cosmosGeoPoint":453,"geoPoint":457,"contacts":458},"Vima Site #023","Kirkland","Washington","98034",{"type":55,"coordinates":454},[455,456],-122.20874,47.68149,{"lat":456,"lon":455},[459],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"facility":461,"status":48,"city":462,"state":451,"zip":463,"country":52,"countryCode":53,"cosmosGeoPoint":464,"geoPoint":468,"contacts":469},"Vima Site #015","Spokane","99202",{"type":55,"coordinates":465},[466,467],-117.42908,47.65966,{"lat":467,"lon":466},[470],{"name":41,"role":42,"phone":43,"phoneExt":34,"email":62},{"type":472,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR","100616321","phase-2-a-study-to-evaluate-the-efficacy-safety-and-tolerability-of-vim0423-in-individuals-with-isolated-dystonia-100616321",false,"NCT07304089","A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia","A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia (Stride Dystonia)","Inclusion Criteria:\n\n* Participant must be male or nonpregnant female between 18 and 65 years of age (inclusive) at Visit 1 (Screening).\n* The participant has a clinical diagnosis of isolated dystonia for at least one year prior to Visit 1 (Screening); has two or more body regions affected by dystonia at Visit 1 (Screening); and has been confirmed by Investigator and Enrollment Authorization Committee.\n* The participant may be untreated with BoNT; OR if the participant is being treated with BoNT as part of their standard of care for dystonia, they must meet protocol-specified criteria.\n* The participants must meet protocol-specified requirements for baseline scores on the BFM and CGI-S.","ALL","18 Years","65 Years",{"count":484,"type":485},100,"ESTIMATED","INTERVENTIONAL",[488],"PHASE2","Stride Dystonia is a randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of VIM0423 in individuals with isolated dystonia.\n\nThe main objectives of this clinical trial are to determine the following:\n\n* Does VIM0423 therapy improve dystonia symptoms compared to placebo?\n* Is VIM0423 well tolerated in individuals with isolated dystonia? and\n* Do the therapeutic effects of VIM0423 confer improvements on daily function and quality of life?",[491],"Dystonia",[491,493,494,495,496,497,498],"Isolated Dystonia","Primary Dystonia","Cervical Dystonia","Segmental Dystonia","Multi-focal Dystonia","Generalized Dystonia","2026-08-03",{"date":501,"type":502},"2026-08-04","ACTUAL",{"date":504,"type":502},"2026-02-05",{"date":506,"type":485},"2027-05",{"name":5,"class":6},37]