[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649597":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":38,"locations":44,"responsibleParty":88,"collaborators":37,"id":90,"slug":91,"hasResults":92,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":96,"eligibilityCriteria":97,"healthyVolunteers":92,"sex":98,"minAge":99,"maxAge":100,"enrollmentInfo":101,"targetDuration":37,"studyType":104,"phases":105,"briefSummary":108,"conditions":109,"keywords":113,"overallStatus":47,"whyStopped":37,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"Misr International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"control group","ACTIVE_COMPARATOR","maxillary sinus membrane is elevated through a lateral window and held in place with screws buccopalatally, similar to tenting.",[13],"Other: maxillary sinus membrane elevation and stabilization.",{"label":15,"type":16,"description":17,"interventionNames":18},"study group","EXPERIMENTAL","enhanced xenograft will be used to augment the maxillary sinus floor",[19],"Biological: Xenograft",[21,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BIOLOGICAL","Xenograft","hydrogel-enhanced xenograft",[15],[27,28,29],"bone augmentation.","xenograft augmentation.","maxillary sinus floor augmentation.",{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"maxillary sinus membrane elevation and stabilization.","graftless augmentation of the maxillary sinus floor through membrane elevation and stabilization; tenting.",[9],[35,36],"graftless augmentation.","tenting.",null,[39],{"name":40,"role":41,"phone":42,"phoneExt":37,"email":43},"Ramy H El Shater, MDS","CONTACT","+201014111431","ramy.hamdy@miuegypt.edu.eg",[45,66,78],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Suez Canal University","RECRUITING","Ismailia","Ismailia Governorate","41522","Egypt","EG",{"type":54,"coordinates":55},"Point",[56,57],32.27225,30.60427,{"lat":57,"lon":56},[60,64],{"name":61,"role":41,"phone":62,"phoneExt":37,"email":63},"El Sholqamy, Professor","+20643205208","president_office@suez.edu.eg",{"name":65,"role":41,"phone":42,"phoneExt":37,"email":43},"Ramy, Assistant Lecturer",{"facility":46,"status":47,"city":48,"state":37,"zip":37,"country":51,"countryCode":52,"cosmosGeoPoint":67,"geoPoint":69,"contacts":70},{"type":54,"coordinates":68},[56,57],{"lat":57,"lon":56},[71,73,75],{"name":72,"role":41,"phone":62,"phoneExt":37,"email":63},"Head of Oral & Maxillofacial Surgery",{"name":74,"role":41,"phone":42,"phoneExt":37,"email":43},"Assistant Lecturer",{"name":76,"role":77,"phone":37,"phoneExt":37,"email":37},"Ramy El Shater, MSc","PRINCIPAL_INVESTIGATOR",{"facility":46,"status":47,"city":48,"state":37,"zip":37,"country":51,"countryCode":52,"cosmosGeoPoint":79,"geoPoint":81,"contacts":82},{"type":54,"coordinates":80},[56,57],{"lat":57,"lon":56},[83,86],{"name":84,"role":41,"phone":85,"phoneExt":37,"email":43},"Mohamed El Sholqamy, Professor","00201014111431",{"name":87,"role":41,"phone":85,"phoneExt":37,"email":37},"Ramy El Shater, Assistant Lecturer",{"type":77,"investigatorFullName":89,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":37,"oldOrganization":37},"Ramy Hamdy Seif El Nasr El Shater","100649597","phase-2-assessment-of-a-new-enhanced-xenograft-in-open-maxillary-sinus-augmentation-100649597",false,"NCT07737704","Assessment of a New Enhanced Xenograft in Open Maxillary Sinus Augmentation","Clinical, Radiographic and Histologic Assessment of a New Xenograft Enhanced With Hydrogel in Augmentation of the Maxillary Sinus: A Randomized Controlled Trial","sinus","Inclusion Criteria:\n\n* Adult male\u002Ffemale patients above the age of 18.\n* Patients with one or more teeth requiring implant supported dental restoration in atrophic posterior maxilla.\n* Alveolar bone height less than 5 mm at the defective site.\n* Good oral hygiene.\n* Patient's consensual agreement to be enrolled in the study.\n\nExclusion Criteria:\n\n* Medically compromised patients with conditions contraindicating surgery (eg. uncontrolled diabetics, bisphosphonate intake, radio or chemotherapy).\n* Patients with active infection at or related to the site of surgery (eg. acute sinusitis).\n* Heavy smokers.\n* Patients not indicated for an implant supported restoration at the time of enrollement.\n\n(Patients developing any medical condition that interferes with the outcomes after enrolment in the study will be excluded).","ALL","18 Years","65 Years",{"count":102,"type":103},30,"ESTIMATED","INTERVENTIONAL",[106,107],"PHASE2","PHASE3","Implant supported dental restorations are sometimes challenging with decreased bone height in the posterior maxilla. The goal of this study is to test an augmentation bone substitute in elevating the maxillary sinus floor; in terms of soft tissue reaction, formed bone height as well as structure.\n\nBone substitute will be compared to a graftless method of bone augmentation depending on participants' bodies forming bone in the defective area.\n\nParticipants will:\n\n* Undergo lateral maxillary sinus floor elevation with bone substitute or graftless method.\n* Record postoperative swelling and pain through the follow up period.\n* Take radiographs for evaluation of the formed bone before placing dental implants.",[110,111,112],"Maxillary Sinus Floor Augmentation","Maxillary Sinus Elevation","Bone Augmentation",[114,115,116,117,118,119,120,121,35,27],"maxillary sinus pneumatization.","severe posterior maxillary ridge atrophy.","inadequate residual bone height.","open sinus augmentation.","lateral maxillary sinus floor elevation.","tenting of the Schneiderian membrane.","staged maxillary sinus floor augmentation and implant placement.","modified xenografts.","2026-07-27",{"date":124,"type":125},"2026-07-30","ACTUAL",{"date":127,"type":103},"2026-08-10",{"date":129,"type":103},"2027-12-12",{"name":5,"class":6},3]