[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609724":3},{"organization":4,"armGroups":7,"interventions":75,"overallOfficials":81,"centralContacts":85,"locations":95,"responsibleParty":113,"collaborators":116,"id":121,"slug":122,"hasResults":123,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":74,"eligibilityCriteria":127,"healthyVolunteers":123,"sex":128,"minAge":129,"maxAge":74,"enrollmentInfo":130,"targetDuration":74,"studyType":133,"phases":134,"briefSummary":136,"conditions":137,"keywords":139,"overallStatus":98,"whyStopped":74,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":156},{"fullName":5,"class":6},"Washington University School of Medicine","OTHER",[8,14,18,22,26,30,34,38,42,46,50,54,58,62,66,70],{"label":9,"type":10,"description":11,"interventionNames":12},"Chatbot targeting weight & shape over-evaluation (WSC)","EXPERIMENTAL","Participant will have access to the chatbot component addressing weight \\& shape over-evaluation. Participant will receive scheduled targeted practice for the weight \\& shape over-evaluation component. At any time, participant will have access to initiate practice in assigned study component.",[13],"Behavioral: Digital Chatbot Program",{"label":15,"type":10,"description":16,"interventionNames":17},"Chatbot targeting dietary restraint (DR)","Participant will have access to the chatbot component addressing dietary restraint. Participant will receive scheduled targeted practice for the dietary restraint component. At any time, participant will have access to initiate practice in assigned study component.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Chatbot targeting emotion dysregulation (ED)","Participant will have access to the chatbot component addressing emotion dysregulation. Participant will receive scheduled targeted practice for the emotion dysregulation component. At any time, participant will have access to initiate practice in assigned study component.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Chatbot targeting resisting urges to binge (UB)","Participant will have access to the chatbot component addressing resisting urges to binge. Participant will receive scheduled targeted practice for the resisting urges to binge component. At any time, participant will have access to initiate practice in assigned study component.",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Chatbot targeting WSC and DR","Participant will have access to the chatbot components addressing weight \\& shape over-evaluation and dietary restraint. Participant will receive scheduled targeted practice for the weight \\& shape over-evaluation and dietary restraint components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":31,"type":10,"description":32,"interventionNames":33},"Chatbot targeting WSC and ED","Participant will have access to the chatbot components addressing weight \\& shape over-evaluation and emotion deregulation. Participant will receive scheduled targeted practice for the weight \\& shape over-evaluation and emotion dysregulation components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":35,"type":10,"description":36,"interventionNames":37},"Chatbot targeting WSC and UB","Participant will have access to the chatbot components addressing weight \\& shape over-evaluation and resisting urges to binge. Participant will receive scheduled targeted practice for the weight \\& shape over-evaluation and resisting urges to binge components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":39,"type":10,"description":40,"interventionNames":41},"Chatbot targeting DR and ED","Participant will have access to the chatbot components addressing dietary restraint and emotion deregulation. Participant will receive scheduled targeted practice for the dietary restraint and emotion dysregulation components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":43,"type":10,"description":44,"interventionNames":45},"Chatbot targeting DR and UB","Participant will have access to the chatbot components addressing dietary restraint and resisting urges to binge. Participant will receive scheduled targeted practice for the dietary restraint and resisting urges to binge components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":47,"type":10,"description":48,"interventionNames":49},"Chatbot targeting ED and UB","Participant will have access to the chatbot components addressing emotion dysregulation and resisting urges to binge. Participant will receive scheduled targeted practice for the emotion dysregulation and resisting urges to binge components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":51,"type":10,"description":52,"interventionNames":53},"Chatbot targeting ED; UB; and DR","Participant will have access to the chatbot components addressing emotion dysregulation, resisting urges to binge, and dietary restraint. Participant will receive scheduled targeted practice for the emotion dysregulation, resisting urges to binge, and dietary restraint components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":55,"type":10,"description":56,"interventionNames":57},"Chatbot targeting ED; UB; and WSC","Participant will have access to the chatbot components addressing emotion dysregulation, resisting urges to binge, and weight and shape over-evaluation. Participant will receive scheduled targeted practice for the emotion dysregulation, resisting urges to binge, and weight and shape over-evaluation components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":59,"type":10,"description":60,"interventionNames":61},"Chatbot targeting ED; DR; and WSC","Participant will have access to the chatbot components addressing emotion dysregulation, dietary restraint, and weight and shape over-evaluation. Participant will receive scheduled targeted practice for the emotion dysregulation, dietary restraint, and weight and shape over-evaluation components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":63,"type":10,"description":64,"interventionNames":65},"Chatbot targeting UB; DR; and WSC","Participant will have access to the chatbot components addressing resisting urges to binge, dietary restraint, and weight and shape over-evaluation. Participant will receive scheduled targeted practice for the resisting urges to binge, emotion dysregulation, dietary restraint and weight, and shape over-evaluation components. At any time, participant will have access to initiate practice in assigned study components",[13],{"label":67,"type":10,"description":68,"interventionNames":69},"Chatbot targeting UB; DR; ED; and WSC","Participant will have access to the chatbot components addressing resisting urges to binge, dietary restraint, emotion dysregulation, and weight and shape over-evaluation. Participant will receive scheduled targeted practice for the resisting urges to binge, emotion dysregulation, dietary restraint, emotion dysregulation, and weight and shape over-evaluation components. At any time, participant will have access to initiate practice in assigned study components.",[13],{"label":71,"type":72,"description":73,"interventionNames":74},"Referral to seek services","NO_INTERVENTION","Those randomized to receive all chatbot components \"off\" will receive a referral to seek services.",null,[76],{"type":77,"name":78,"description":79,"armGroupLabels":80,"otherNames":74},"BEHAVIORAL","Digital Chatbot Program","Wysa is a digital rules-based chatbot program platform offering cognitive-behavioral therapy-based guided self-help modules. Participants in an arm with access to Wysa will engage with the digital chatbot program daily for eight weeks.",[39,43,47,59,51,55,67,63,27,31,35,15,19,23,9],[82],{"name":83,"affiliation":5,"role":84},"Ellen Fitzsimmons-Craft, Ph.D.","PRINCIPAL_INVESTIGATOR",[86,91],{"name":87,"role":88,"phone":89,"phoneExt":74,"email":90},"Marianna B. Horton, B.S.\u002FB.A.","CONTACT","3149355843","m.horton@wustl.edu",{"name":92,"role":88,"phone":93,"phoneExt":74,"email":94},"Nathalie A. Gullo, B.S.\u002FB.A.","6469195177","gullo@wustl.edu",[96],{"facility":97,"status":98,"city":99,"state":100,"zip":101,"country":102,"countryCode":103,"cosmosGeoPoint":104,"geoPoint":109,"contacts":110},"Washington University in St. Louis","RECRUITING","St Louis","Missouri","63105","United States","US",{"type":105,"coordinates":106},"Point",[107,108],-90.19789,38.62727,{"lat":108,"lon":107},[111,112],{"name":87,"role":88,"phone":89,"phoneExt":74,"email":90},{"name":83,"role":84,"phone":74,"phoneExt":74,"email":74},{"type":84,"investigatorFullName":114,"investigatorTitle":115,"investigatorAffiliation":5,"oldNameTitle":74,"oldOrganization":74},"Ellen E. Fitzsimmons-Craft","Associate Professor of Psychological & Brain Sciences and Psychiatry",[117,119],{"name":118,"class":6},"New York University",{"name":120,"class":6},"University of South Carolina","100609724","phase-2-eating-disorder-chatbot-optimization-100609724",false,"NCT07218302","Eating Disorder Chatbot Optimization","Optimizing an Automated Chatbot to Achieve Efficient, Scalable Treatment for Eating Disorders","Inclusion Criteria:\n\n* 18+ years old\n* Owns a smartphone\n* Speaks English\n* US resident\n* Screens for a clinical or subclinical eating disorder\n* Low suicidality\n* Not currently in treatment for an eating disorder\n* Does not have a medical condition or take medications that impact appetite\u002Fweight\n* Not currently pregnant\n\nExclusion Criteria:\n\n* Below 18 years of age\n* Does not own a smartphone\n* Does not speak English\n* Lives outside the US\n* Screens as: at risk for an eating disorder, anorexia nervosa, atypical anorexia nervosa, avoidant\u002Frestrictive food intake disorder, or not at risk for an ED\n* High suicidality\n* In treatment for an eating disorder\n* Has a medical condition or takes medication(s) that impact appetite\u002Fweight\n* Currently pregnant","ALL","18 Years",{"count":131,"type":132},800,"ESTIMATED","INTERVENTIONAL",[135],"PHASE2","The purpose of this study is to optimize an automated digital chatbot intervention for adults with clinical or subclinical eating disorders.",[138],"Eating Disorders",[140,141,142,143,144,145,146],"Eating Disorder Intervention","Eating Pathology","Eating Disorder Symptoms","Digital Mental Health","Chatbot","Optimization Randomized Control Trial","Multiphase Optimization Strategy","2026-07-20",{"date":149,"type":150},"2026-07-21","ACTUAL",{"date":152,"type":150},"2026-07-17",{"date":154,"type":132},"2029-07-31",{"name":5,"class":6},1]