[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553913":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":27,"centralContacts":31,"locations":41,"responsibleParty":57,"collaborators":24,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":24,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":24,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Emergency Stroke Unit based on 0.23-T MRI","EXPERIMENTAL","The participants with hyperacute ischemic stroke (between 4.5-6 hours after onset of symptoms) who are eligible to receive reperfusion therapy will be managed by Emergency Stroke Unit process based on low-field magnetic resonance imaging.",[13],"Combination Product: Emergency Stroke Unit based on 0.23-T MRI",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard stroke unit adherent to guidelines","PLACEBO_COMPARATOR","The participants with hyperacute ischemic stroke (between 4.5-6 hours after onset of symptoms) who are eligible to receive reperfusion therapy will be managed by standard stroke unit process adherent to guidelines.",[19],"Combination Product: Standard stroke unit adherent to guidelines",[21,25],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"COMBINATION_PRODUCT",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":26,"otherNames":24},[15],[28],{"name":29,"affiliation":5,"role":30},"Yongjun Wang, MD, PhD","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":24,"email":36},"Yongjun Wang","CONTACT","59978555","yongjunwang111@aliyun.com",{"name":38,"role":34,"phone":39,"phoneExt":24,"email":40},"Jing Jing","15810312511","jingj_bjttyy@163.com",[42],{"facility":43,"status":44,"city":45,"state":24,"zip":24,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Beijing Tiantan Hospital, Capital Medical University","RECRUITING","Beijing","China","CN",{"type":49,"coordinates":50},"Point",[51,52],116.39723,39.9075,{"lat":52,"lon":51},[55],{"name":56,"role":34,"phone":24,"phoneExt":24,"email":24},"Yongjun Wang, Dr.",{"type":58,"investigatorFullName":33,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","professor","100553913","phase-2-emergency-stroke-unit-for-acute-cerebrovascular-events--esu-ace-b--100553913",false,"NCT06492265","Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-B )","Emergency Stroke Unit for Acute Cerebrovascular Events--A Prospective, Multicenter, Week-wise Randomized, Controlled Trial ( ESU-ACE-B )","Inclusion Criteria:\n\n1. Age ≥ 18 years;\n2. Can be treated between 4.5-6 hours of symptoms onset\\*(\\*Symptom onset is defined by the \"last seen normal\" principle);\n3. Presenting with ischemic stroke symptoms;\n4. Pre-stroke mRS score 0-1;\n5. Baseline NIHSS score ≥ 5;\n6. Eligible for endovascular thrombectomy;\n7. Informed consent signed.\n\nExclusion Criteria:\n\n1. Baseline NIHSS score \\\u003C 5;\n2. Unable to undergo MRI because of claustrophobia;\n3. Patients with cardiac pacemaker\u002Fbrain pacemaker\u002Finsulin pump implantation;\n4. Definite contraindication for endovascular thrombectomy;\n5. Patients with postictal hemiparesis (Todd's paralysis) or those with concomitant neurological\u002Fpsychiatric conditions who are unable or unwilling to cooperate;\n6. Pregnant women, nursing mothers, or reluctance to use effective contraceptive measures during the period of trial;\n7. Participation in other interventional randomized clinical trials within 3 months before enrollment;\n8. Patients deemed unsuitable for participation in this trial by the investigator or those for whom participation in this trial may result in greater risks.","ALL","18 Years",{"count":70,"type":71},100,"ESTIMATED","INTERVENTIONAL",[74],"PHASE2","To compare the door-to-puncture time of patients with hyperacute ischemic stroke (between 4.5-6 hours after the onset of symptoms) treated in a standard stroke unit adherent to guidelines versus treated in Emergency Stroke Unit (a new stroke unit based on low-field magnetic resonance imaging).",[77],"Ischemic Stroke, Acute",[79,80,81,82],"Emergency stroke unit","Low-field magnetic resonance imaging","Reperfusion therapy","Endovascular therapy","2024-08-09",{"date":85,"type":86},"2024-08-12","ACTUAL",{"date":88,"type":86},"2024-08-04",{"date":90,"type":71},"2025-04-01",{"name":33,"class":6},1]