[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100342529":3},{"organization":4,"outcomesModule":7,"designInfo":59,"detailedDescription":65,"studyPopulation":33,"armGroups":66,"interventions":87,"overallOfficials":153,"centralContacts":33,"locations":158,"responsibleParty":2677,"collaborators":33,"id":2679,"slug":2680,"hasResults":2681,"nctId":2682,"briefTitle":2683,"officialTitle":2684,"acronym":33,"eligibilityCriteria":2685,"healthyVolunteers":2681,"sex":2686,"minAge":2687,"maxAge":33,"enrollmentInfo":2688,"targetDuration":33,"studyType":2691,"phases":2692,"briefSummary":2694,"conditions":2695,"keywords":33,"overallStatus":276,"whyStopped":33,"lastUpdateSubmitDate":2699,"lastUpdatePostDateStruct":2700,"startDateStruct":2703,"completionDateStruct":2705,"leadSponsor":2707,"locationsCount":2708},{"fullName":5,"class":6},"National Cancer Institute (NCI)","NIH",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":40},[9,13],{"measure":10,"description":11,"timeFrame":12},"Event-free survival","Will be defined as time from start of treatment to failure to achieve complete response (CR)\u002Fcomplete response with incomplete count recovery (CRi) after completing Course II of blinatumomab, relapse after CR\u002FCRi, progression on study requiring withdrawal from study therapy, or death from any cause","At 1 year",{"measure":14,"description":15,"timeFrame":16},"Completion of protocol treatment (cohort 3)","Feasibility defined as completion of the planned therapy as defined in the protocol. Success rate defined as the proportion of patients who either complete entire protocol treatment or go off protocol treatment due to the disease (e.g., refractory disease, progression, and relapse).","Up to 10 years",[18,22,25,28,31,34,37],{"measure":19,"description":20,"timeFrame":21},"Overall survival (OS)","Will be evaluated using the Kaplan-Meier method. A 95% confidence interval for the 1- and 3-year rates will be constructed using a point-wise confidence interval for the survival function based on a log-minus-log transformation. Will also calculate a 95% confidence interval by using a point-wise confidence interval for the survival function based on a log-minus-log transformation.","Time from start of study therapy to death from any cause censored at the last known alive date, assessed up to 10 years",{"measure":23,"description":20,"timeFrame":24},"Relapse-free survival (RFS)","Time from first CR\u002FCRi to progressive disease (relapse, treatment discontinuation due to health deterioration) or death, assessed up to 10 years",{"measure":26,"description":20,"timeFrame":27},"Event-free survival (EFS)","Time from start of treatment to failure to achieve CR\u002FCRi after completing Course II of blinatumomab, relapse after CR\u002FCRi, progression on study requiring withdrawal from study therapy, or death from any cause, assessed up to 10 years",{"measure":29,"description":30,"timeFrame":16},"Complete and overall response rate","Point and interval estimates of the rates will be shown using a 95% binomial confidence interval.",{"measure":32,"description":33,"timeFrame":16},"Minimal residual disease negativity",null,{"measure":35,"description":36,"timeFrame":16},"Complete molecular response","Defined as negative BCR-ABL1 quantitative real time polymerase chain reaction on bone marrow aspirate in patients in CR\u002Fcomplete response with partial hematologic recovery\u002FCRi.",{"measure":38,"description":39,"timeFrame":16},"Allogeneic hematopoietic cell transplantation rate (Cohort 2)","Point and interval estimates of the rate will be shown using a 95% binomial confidence interval.",[41,43,46,50,53,56],{"measure":42,"description":39,"timeFrame":16},"Rate of cytokine release syndrome (Cohort 1)",{"measure":44,"description":45,"timeFrame":16},"Sinusoidal obstruction syndrome\u002Fveno-occlusive disease (SOS\u002FVOD) of the liver","The rate of, timing of, and risk factors for SOS\u002FVOD of the liver after limited inotuzumab ozogamicin exposure. Point and interval estimates of the rate will be shown using a 95% binomial confidence interval. A summary of the timing and risk factors for SOS\u002FVOD of the liver will be provided.",{"measure":47,"description":48,"timeFrame":49},"OS","Will compare between patients achieving CR\u002FCRi and receiving consolidation with allogeneic hematopoietic cell transplantation versus (vs.) patients achieving CR\u002FCRi and receiving consolidation without allogeneic hematopoietic cell transplantation. The median, 1-year, and 2-year OS will be compared between the above two groups. The distribution of OS for each group will be estimated using the Kaplan-Meier method.","Up to 2 years",{"measure":51,"description":52,"timeFrame":49},"RFS","Will compare between patients achieving CR\u002FCRi and receiving consolidation with allogeneic hematopoietic cell transplantation vs. patients achieving CR\u002FCRi and receiving consolidation without allogeneic hematopoietic cell transplantation. The median, 1-year, and 2-year RFS will be compared between the above two groups. The distribution of RFS for each treatment arm will be estimated using the Kaplan-Meier method.",{"measure":54,"description":55,"timeFrame":49},"Cumulative incidence of relapse (CIR)","Will compare between patients achieving CR\u002FCRi and receiving consolidation with allogeneic hematopoietic cell transplantation vs. patients achieving CR\u002FCRi and receiving consolidation without allogeneic hematopoietic cell transplantation. Competing risk analysis will be done to compare the relapse rates between the above two groups. In this analysis, death will be considered a competing event. Relapse rates at the 1-year and 2-year time points will be estimated. Other time points of interest may be estimated as well.",{"measure":57,"description":58,"timeFrame":49},"Non-relapse mortality","Will compare between patients achieving CR\u002FCRi and receiving consolidation with allogeneic hematopoietic cell transplantation vs. patients achieving CR\u002FCRi and receiving consolidation without allogeneic hematopoietic cell transplantation. Competing risk analysis will be done to compare the mortality rates between the above two groups. In this analysis, relapse will be considered a competing event. Mortality rates at the 1-year and 2-year time points will be estimated. Other time points may be estimated as well.",{"allocation":60,"interventionModel":61,"interventionModelDescription":33,"primaryPurpose":62,"observationalModel":33,"timePerspective":33,"maskingInfo":63},"NON_RANDOMIZED","PARALLEL","TREATMENT",{"masking":64,"maskingDescription":33,"whoMasked":33},"NONE","PRIMARY OBJECTIVES:\n\nIa. For Philadelphia (Ph)-negative B-cell acute lymphoblastic leukemia (ALL), to confirm tolerability of the combination regimen of inotuzumab ozogamicin followed by blinatumomab.\n\nIb. For Ph-positive B-cell ALL, to confirm tolerability of ponatinib in combination with inotuzumab ozogamicin and blinatumomab.\n\nII. To estimate the 1-year event-free survival of older, transplant-ineligible patients with newly diagnosed, Ph-negative, CD22-positive, B-cell acute lymphoblastic leukemia (ALL) treated with inotuzumab ozogamicin induction followed by blinatumomab consolidation. (Cohort 1) III. To estimate the 1-year event-free survival of patients with relapsed or refractory Ph-negative, CD22-positive, B-cell ALL treated with inotuzumab ozogamicin induction followed by blinatumomab consolidation. (Cohort 2) IV. To determine the feasibility of the regimen in adult patients with CD22-positive, Ph\u002FBCR-ABL1-positive B-cell ALL. (Cohort 3)\n\nSECONDARY OBJECTIVES:\n\nI. To estimate the median, 1-year, and 3-year overall survival (OS) in all eligible patients. (Cohort 1) II. To estimate the median, 1-year, and 3-year relapse-free survival (RFS) in all eligible patients. (Cohort 1) III. To estimate the median and 3-year event-free survival (EFS) in all eligible patients. (Cohort 1) IV. To estimate the complete response (CR) rate and overall response rate (ORR, defined as complete response \\[CR\\] + complete response with incomplete count recovery \\[CRi\\]) to inotuzumab ozogamicin followed by blinatumomab (regimen CR rate and ORR). (Cohort 1) V. To estimate the CR rate and ORR (CR + CRi) to inotuzumab ozogamicin induction alone (induction CR and ORR). (Cohort 1) VI. To estimate the minimal residual disease (MRD) negativity rate in subjects achieving a CR or CRi. (Cohort 1) VII. To estimate the treatment-related mortality with this regimen. (Cohort 1) VIII. To describe the safety and tolerability of this regimen. (Cohort 1) IX. To estimate the median, 1-year, and 3-year OS in all eligible patients. (Cohort 2) X. To estimate the median, 1-year, and 3-year RFS in all eligible patients. (Cohort 2) XI. To estimate the median and 3-year EFS in all eligible patients. (Cohort 2) XII. To estimate ORR (CR\u002FCRi and CR\u002Fcomplete response with partial hematologic recovery \\[CRh\\]) to blinatumomab in patients with ALL refractory to inotuzumab ozogamicin. (Cohort 2) XIII. To estimate the CR, CRi, and CRh rates at defined time points and cumulatively for the entire regimen. (Cohort 2) XIV. To determine the MRD negativity (\\\u003C 10\\^-4) rate at defined time points including prior to allogeneic HCT and cumulatively in patients achieving a CR, CRh, or CRi. (Cohort 2) XV. To determine the allogeneic hematopoietic cell transplantation (HCT) rate in eligible subjects. (Cohort 2) XVI. To estimate the treatment-related mortality with this regimen. (Cohort 2) XVII. To describe the safety and tolerability of this regimen. (Cohort 2) XVIII. To estimate the 24-week complete molecular response rate. (Cohort 3) XIX. To estimate the median, 1-year, and 3-year OS in all eligible patients. (Cohort 3) XX. To estimate the median, 1-year, and 3-year RFS in all eligible patients. (Cohort 3) XXI. To estimate the median and 3-year EFS in all eligible patients. (Cohort 3) XXII. To estimate ORR (CR\u002FCRi and CR\u002Fcomplete response with partial hematologic recovery \\[CRh\\]) to blinatumomab in patients with ALL refractory to inotuzumab ozogamicin. (Cohort 3) XXIII. To estimate the CR, CRi, and CRh rates at defined time points and cumulatively for the entire regimen. (Cohort 3) XXIV. To determine the complete molecular response rate at defined time points and cumulatively in patients achieving a CR, CRh, or CRi. (Cohort 3) XXV. To estimate the treatment-related mortality with this regimen. (Cohort 3) XXVI. To describe the safety and tolerability of this regimen. (Cohort 3)\n\nOTHER OBJECTIVE:\n\nI. Results of the primary analysis will be examined for consistency, while accounting for the stratification factors and\u002For covariates of baseline quality of life (QOL) and fatigue.\n\nCORRELATIVE SCIENCE OBJECTIVES:\n\nI. To correlate specific karyotype groups (normal or various primary and secondary chromosomal abnormalities) with clinical and laboratory parameters.\n\nII. To correlate specific karyotype groups with response rates, response duration, survival, and cure in patients treated with inotuzumab ozogamicin followed by blinatumomab.\n\nIII. To correlate specific karyotype groups with MRD. IV. To determine karyotype changes at relapse and the influence of the type of change (or no change) in karyotype at relapse.\n\nV. To assess the correlation of quantitative MRD post-induction with inotuzumab ozogamicin and at sequential consolidation time points with blinatumomab with RFS, EFS, and OS.\n\nVI. To correlate the influence of MRD status (detectable versus \\[vs.\\] not and as a continuous measure) in relation to EFS, RFS, and OS with other clinical and biological factors (e.g. previously untreated vs. relapsed disease cohorts; age, initial white blood cell \\[WBC\\] count, cytogenetics).\n\nVII. To identify genetic variants and predictors of ex vivo resistance. VIII. To identify genetic variants and predictors of MRD. IX. To identify genetic variants and predictors of relapse. X. To determine inter-patient variability in drug sensitivity of adult ALL. XI. To examine the associations of drug sensitivity with host and leukemia molecular features.\n\nXII. To evaluate T-cell populations and T-cell function during therapy using T-cell markers which include the T-cell subset defining markers CD45, CD3, CD4, CD8, CD45RA, CD45RO, CCR7, CD25, CD127, FOXP3, CD 27, CD28, among others, and markers of T cell exhaustion and senescence including CD57, PD-1, Tim-3, LAG-3, TIGIT, CTLA4, CD160, and ICOS among others.\n\nXIII. To evaluate cytokine levels, and compare between patients who attain a CR vs. those with stable or progressive disease.\n\nEXPLORATORY OBJECTIVES:\n\nI. To estimate the median, 1-year, and 3-year RFS, EFS, and OS in patients achieving a CR\u002FCRi to inotuzumab ozogamicin. (Cohort 1) II. To compare the median, 1-year, and 3-year RFS, EFS, and OS among patients achieving MRD-negative vs. MRD-positive CR\u002FCRi to inotuzumab ozogamicin. (Cohort 1) III. To compare the median, 1-year, and 3-year RFS, EFS, and OS among patients achieving MRD-negative vs. MRD-positive CR\u002FCRi at any time. (Cohort 1) IV. To describe the rate, severity, and timing of sinusoidal obstruction syndrome\u002Fveno-occlusive disease (SOS\u002FVOD) of the liver after limited inotuzumab ozogamicin exposure and identify risk factors for SOS\u002FVOD. (Cohort 1) V. To estimate the rate of cytokine release syndrome in this population. (Cohort 1) VI. To estimate the median, 1-year, and 3-year RFS from time of CR\u002FCRi to inotuzumab ozogamicin in patients receiving inotuzumab ozogamicin followed by blinatumomab and not undergoing allogeneic hematopoietic cell transplantation (HCT). (Cohort 2) VII. To estimate median, 1-year, and 3-year OS after CR\u002FCRi to inotuzumab ozogamicin in patients not undergoing allogeneic HCT. (Cohort 2) VIII. To compare in a non-randomized fashion median, 1-year, and 3-year OS, median, 1-year, and 3-year RFS, cumulative incidence of relapse (CIR), and non-relapse mortality (NRM) between patients achieving CR\u002FCRi and receiving consolidation with or without allogeneic HCT. (Cohort 2) IX. To describe the rate, severity, and timing of sinusoidal obstruction syndrome\u002Fveno-occlusive disease (SOS\u002FVOD) of the liver after limited inotuzumab ozogamicin exposure and identify risk factors for SOS\u002FVOD. (Cohort 2) X. To estimate the rate of cytokine release syndrome in this population. (Cohort 2) XI. To estimate the median, 1-year, and 3-year RFS, EFS, and OS in patients achieving a CR\u002FCRi to inotuzumab ozogamicin. (Cohort 3) XII. To compare the median, 1-year, and 3-year RFS, EFS, and OS among patients with CR\u002FCRi achieving complete molecular response vs. not to inotuzumab ozogamicin. (Cohort 3) XIII. To compare the median, 1-year, and 3-year RFS, EFS, and OS among patients achieving CR\u002FCRi achieving complete molecular response vs. not at any time. (Cohort 3) XIV. To describe the rate, severity, and timing of sinusoidal obstruction syndrome\u002Fveno-occlusive disease (SOS\u002FVOD) of the liver after limited inotuzumab ozogamicin exposure and identify risk factors for SOS\u002FVOD. (Cohort 3) XV. To estimate the rate of cytokine release syndrome in this population. (Cohort 3) XVI. To assess ABL1 mutational patterns at relapse. (Cohort 3)\n\nOUTLINE: Patients are assigned to 1 of 2 cohorts.\n\nCOHORT 1: Patients receive inotuzumab ozogamicin intravenously (IV) over 1 hour on day 1, 8, and 15 (Course IA). By the end of Course IA (day 21), patients with adequate ALL cytoreduction continue to Course IB\u002FIC, and patients who fail to achieve ALL cytoreduction continue to Course II. By the end of Course II, patients with CR-CRi to Course IB\u002FIC and Course II continue to Course IIIA, patients without adequate ALL cytoreduction to Course IA or refractory to Course IB\u002FIC but CR\u002FCRi to Course II continue to Course IIIB. Patients undergo bone marrow aspiration and biopsy and blood sample collection throughout the study. Patients undergo lumbar puncture with cerebrospinal fluid sample collection at baseline and may undergo additionally throughout the study.\n\nCOHORT 2: Patients receive inotuzumab ozogamicin IV over 1 hour on day 1, 8, and 15 (Course IA). By the end of Course IA (day 21), patients with adequate ALL cytoreduction continue to Course IB\u002FIC, and patients who fail to achieve ALL cytoreduction continue to Course II. Patients with CR\u002FCRi at the end of Course II continue to Course IIIB.\n\nCOURSE IB\u002FIC: Patients receive inotuzumab ozogamicin IV over 1 hour on days 1, 8, and 15. Treatment continues for 1 course (28 days) in the absence of disease progression or unacceptable toxicity.\n\nCOURSE II: Patients receive blinatumomab IV continuously on days 1-28 and 43-70. Treatment continues for 1 course (84 days) in the absence of disease progression or unacceptable toxicity.\n\nCOURSE IIIA: Patients receive blinatumomab IV continuously on days 1-28 and 43-70. Treatment continues for 1 course (84 days) in the absence of disease progression or unacceptable toxicity.\n\nCOURSE IIIB: Patients receive blinatumomab IV continuously on days 1-28, 43-70, and 85-112. Treatment continues for 1 course (126 days) in the absence of disease progression or unacceptable toxicity.\n\nPatients undergo bone marrow aspiration and biopsy and blood sample collection throughout the study. Patients undergo lumbar puncture with cerebrospinal fluid sample collection at baseline and may undergo additionally throughout the study.\n\nCOHORT 3:\n\nINDUCTION:\n\nCOURSE I: Patients receive ponatinib orally (PO) daily (QD) on day 1-35, dexamethasone PO QD on days 1-7 and 15-21 and methotrexate intrathecally (IT) on day 1, 15 and 29 for 1 course (35 days) in the absence of disease progression or unacceptable toxicity. Patients with CR or CRi continue to consolidation course IIA or end the study treatment to receive allogenic HCT per the treating physician. Patients without CR or CRi with but adequate ALL cytoreduction (defined as ≥ 50% reduction in bone marrow lymphoblasts from the pre-registration bone marrow aspirate\u002Fbiopsy and\u002For ≤ 20% marrow cellularity at the end of Course I bone marrow aspirate\u002Fbiopsy) also proceed to consolidation course IIA. Patients with progression or failure to achieve adequate ALL cytoreduction are removed from study treatment.\n\nCONSOLIDATION:\n\nCOURSE IIA: Patients receive ponatinib PO QD on days 1-21, inotuzumab ozogamicin IV over 1 hour on days 1, 8 and 15 and methotrexate IT on day 1 for 1 course (21 days) in the absence of disease progression or unacceptable toxicity. Patients with CR or CRi continue to consolidation course IIB or end the study treatment to receive allogenic HCT per the treating physician. Patients without CR or CRi and without progressive disease proceed to course IIC. Patients with progression are removed from study treatment.\n\nCOURSE IIB\u002FC: Patients receive ponatinib PO QD on days 1-28, inotuzumab ozogamicin IV over 1 hour on days 1, 8 and 15 and methotrexate IT on day 1 for 1 course (28 days) in the absence of disease progression or unacceptable toxicity. Patients with CR or CRi end the study treatment to receive allogenic HCT per the treating physician. Patients with progression are removed from study treatment. All other patients proceed to course III.\n\nCOURSE III: Patients receive ponatinib PO QD on days 1-84 and receive blinatumomab IV continuously on days 1-28 and 43-70. Treatment continues for 1 course (84 days) in the absence of disease progression or unacceptable toxicity. Patients in CR\u002FCRi proceed to course IV. Patients not in CR\u002FCRi are removed from study treatment.\n\nCOURSE IV: Patients receive ponatinib PO QD on days 1-84 and receive blinatumomab IV continuously on days 1-28 and 43-70. Treatment continues for 1 course (84 days) in the absence of disease progression or unacceptable toxicity. Patients in CR\u002FCRi proceed to maintenance. Patients not in CR\u002FCRi are removed from study treatment.\n\nMAINTENANCE: Patients receive ponatinib PO QD for 24 months in the absence of disease progression or unacceptable toxicity.\n\nPatients undergo bone marrow aspiration and biopsy and blood sample collection throughout the study. Patients undergo lumbar puncture with cerebrospinal fluid sample collection at baseline and may undergo additionally throughout the study.\n\nAfter completion of study treatment, patients are followed up every 3 months for 3 years, and then every 6 months for up to 10 years.",[67,77,82],{"label":68,"type":69,"description":70,"interventionNames":71},"Cohort 1 (inotuzumab ozogamicin, blinatumomab)","EXPERIMENTAL","See Detailed Description..",[72,73,74,75,76],"Procedure: Biospecimen Collection","Biological: Blinatumomab","Procedure: Bone Marrow Biopsy","Biological: Inotuzumab Ozogamicin","Procedure: Lumbar Puncture",{"label":78,"type":69,"description":79,"interventionNames":80},"Cohort 2 (inotuzumab ozogamicin, blinatumomab)","See Detailed Description.",[72,73,81,74,75,76],"Procedure: Bone Marrow Aspiration",{"label":83,"type":69,"description":84,"interventionNames":85},"Cohort 3 (inotuzumab ozogamicin, blinatumomab, ponatinib))","See detailed description",[72,73,81,74,75,76,86],"Drug: Ponatinib",[88,98,116,120,127,137,144],{"type":89,"name":90,"description":91,"armGroupLabels":92,"otherNames":93},"PROCEDURE","Biospecimen Collection","Undergo blood sample and cerebrospinal fluid collection",[68,78,83],[94,95,96,97],"Biological Sample Collection","Biospecimen Collected","Sample Collection","Specimen Collection",{"type":99,"name":100,"description":101,"armGroupLabels":102,"otherNames":103},"BIOLOGICAL","Blinatumomab","Given IV",[68,78,83],[104,105,106,107,108,109,110,111,112,113,114,115],"AMG 103","AMG-103","AMG103","Anti-CD19 x Anti-CD3 Bispecific Monoclonal Antibody","Anti-CD19\u002FAnti-CD3 Recombinant Bispecific Monoclonal Antibody MT103","Blincyto","MEDI 538","MEDI-538","MEDI538","MT 103","MT-103","MT103",{"type":89,"name":117,"description":118,"armGroupLabels":119,"otherNames":33},"Bone Marrow Aspiration","Undergo bone marrow aspiration",[78,83],{"type":89,"name":121,"description":122,"armGroupLabels":123,"otherNames":124},"Bone Marrow Biopsy","Undergo bone marrow biopsy",[68,78,83],[125,126],"Biopsy of Bone Marrow","Biopsy, Bone Marrow",{"type":99,"name":128,"description":101,"armGroupLabels":129,"otherNames":130},"Inotuzumab Ozogamicin",[68,78,83],[131,132,133,134,135,136],"Besponsa","CMC 544","CMC-544","CMC544","Way 207294","WAY-207294",{"type":89,"name":138,"description":139,"armGroupLabels":140,"otherNames":141},"Lumbar Puncture","Undergo lumbar puncture",[68,78,83],[142,143],"LP","Spinal Tap",{"type":145,"name":146,"description":147,"armGroupLabels":148,"otherNames":149},"DRUG","Ponatinib","Given PO",[83],[150,151,152],"AP 24534","AP-24534","AP24534",[154],{"name":155,"affiliation":156,"role":157},"Matthew J Wieduwilt","Alliance for Clinical Trials in Oncology","PRINCIPAL_INVESTIGATOR",[159,173,184,190,196,201,206,211,216,221,231,241,251,260,269,274,292,307,322,334,343,353,362,371,382,390,396,405,414,423,438,448,463,478,488,498,507,516,531,536,545,555,564,573,582,591,600,609,618,633,644,656,671,676,685,697,706,720,729,734,746,758,767,776,785,794,808,817,826,838,847,859,868,877,882,896,901,907,913,922,927,936,945,950,956,965,975,984,999,1011,1021,1031,1040,1055,1067,1075,1086,1094,1103,1115,1123,1132,1137,1151,1159,1173,1178,1186,1194,1205,1210,1218,1227,1236,1244,1255,1260,1269,1278,1283,1288,1296,1305,1317,1323,1332,1344,1353,1362,1367,1375,1380,1389,1400,1409,1420,1430,1439,1448,1457,1462,1477,1489,1498,1507,1516,1521,1530,1535,1544,1553,1561,1567,1576,1585,1597,1606,1612,1621,1630,1639,1647,1657,1667,1673,1683,1692,1697,1702,1707,1713,1718,1723,1728,1733,1741,1747,1758,1763,1769,1775,1780,1786,1791,1797,1802,1807,1812,1818,1824,1829,1834,1839,1844,1849,1854,1859,1865,1871,1876,1881,1887,1893,1899,1905,1910,1919,1928,1937,1943,1949,1959,1973,1985,1997,2005,2018,2032,2042,2051,2060,2074,2090,2105,2117,2133,2139,2149,2158,2163,2172,2181,2190,2205,2214,2220,2229,2239,2248,2257,2266,2275,2284,2300,2309,2318,2327,2335,2344,2353,2362,2371,2380,2389,2398,2407,2413,2419,2425,2434,2443,2452,2461,2470,2479,2495,2511,2520,2526,2538,2552,2565,2577,2590,2602,2614,2626,2638,2650,2667],{"facility":160,"status":161,"city":162,"state":163,"zip":164,"country":165,"countryCode":166,"cosmosGeoPoint":167,"geoPoint":172,"contacts":33},"University of Alabama at Birmingham Cancer Center","ACTIVE_NOT_RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":168,"coordinates":169},"Point",[170,171],-86.80249,33.52066,{"lat":171,"lon":170},{"facility":174,"status":175,"city":176,"state":177,"zip":178,"country":165,"countryCode":166,"cosmosGeoPoint":179,"geoPoint":183,"contacts":33},"Anchorage Associates in Radiation Medicine","SUSPENDED","Anchorage","Alaska","98508",{"type":168,"coordinates":180},[181,182],-149.90028,61.21806,{"lat":182,"lon":181},{"facility":185,"status":175,"city":176,"state":177,"zip":186,"country":165,"countryCode":166,"cosmosGeoPoint":187,"geoPoint":189,"contacts":33},"Anchorage Radiation Therapy Center","99504",{"type":168,"coordinates":188},[181,182],{"lat":182,"lon":181},{"facility":191,"status":175,"city":176,"state":177,"zip":192,"country":165,"countryCode":166,"cosmosGeoPoint":193,"geoPoint":195,"contacts":33},"Alaska Breast Care and Surgery LLC","99508",{"type":168,"coordinates":194},[181,182],{"lat":182,"lon":181},{"facility":197,"status":175,"city":176,"state":177,"zip":192,"country":165,"countryCode":166,"cosmosGeoPoint":198,"geoPoint":200,"contacts":33},"Alaska Oncology and Hematology LLC",{"type":168,"coordinates":199},[181,182],{"lat":182,"lon":181},{"facility":202,"status":175,"city":176,"state":177,"zip":192,"country":165,"countryCode":166,"cosmosGeoPoint":203,"geoPoint":205,"contacts":33},"Alaska Women's Cancer Care",{"type":168,"coordinates":204},[181,182],{"lat":182,"lon":181},{"facility":207,"status":175,"city":176,"state":177,"zip":192,"country":165,"countryCode":166,"cosmosGeoPoint":208,"geoPoint":210,"contacts":33},"Anchorage Oncology Centre",{"type":168,"coordinates":209},[181,182],{"lat":182,"lon":181},{"facility":212,"status":175,"city":176,"state":177,"zip":192,"country":165,"countryCode":166,"cosmosGeoPoint":213,"geoPoint":215,"contacts":33},"Katmai Oncology Group",{"type":168,"coordinates":214},[181,182],{"lat":182,"lon":181},{"facility":217,"status":175,"city":176,"state":177,"zip":192,"country":165,"countryCode":166,"cosmosGeoPoint":218,"geoPoint":220,"contacts":33},"Providence Alaska Medical Center",{"type":168,"coordinates":219},[181,182],{"lat":182,"lon":181},{"facility":222,"status":175,"city":223,"state":224,"zip":225,"country":165,"countryCode":166,"cosmosGeoPoint":226,"geoPoint":230,"contacts":33},"Kingman Regional Medical Center","Kingman","Arizona","86401",{"type":168,"coordinates":227},[228,229],-114.05301,35.18944,{"lat":229,"lon":228},{"facility":232,"status":175,"city":233,"state":234,"zip":235,"country":165,"countryCode":166,"cosmosGeoPoint":236,"geoPoint":240,"contacts":33},"Mercy Hospital Fort Smith","Fort Smith","Arkansas","72903",{"type":168,"coordinates":237},[238,239],-94.39855,35.38592,{"lat":239,"lon":238},{"facility":242,"status":175,"city":243,"state":244,"zip":245,"country":165,"countryCode":166,"cosmosGeoPoint":246,"geoPoint":250,"contacts":33},"PCR Oncology","Arroyo Grande","California","93420",{"type":168,"coordinates":247},[248,249],-120.59073,35.11859,{"lat":249,"lon":248},{"facility":252,"status":175,"city":253,"state":244,"zip":254,"country":165,"countryCode":166,"cosmosGeoPoint":255,"geoPoint":259,"contacts":33},"Providence Saint Joseph Medical Center\u002FDisney Family Cancer Center","Burbank","91505",{"type":168,"coordinates":256},[257,258],-118.30897,34.18084,{"lat":258,"lon":257},{"facility":261,"status":161,"city":262,"state":244,"zip":263,"country":165,"countryCode":166,"cosmosGeoPoint":264,"geoPoint":268,"contacts":33},"Community Cancer Institute","Clovis","93611",{"type":168,"coordinates":265},[266,267],-119.70292,36.82523,{"lat":267,"lon":266},{"facility":270,"status":161,"city":262,"state":244,"zip":263,"country":165,"countryCode":166,"cosmosGeoPoint":271,"geoPoint":273,"contacts":33},"University Oncology Associates",{"type":168,"coordinates":272},[266,267],{"lat":267,"lon":266},{"facility":275,"status":276,"city":277,"state":244,"zip":278,"country":165,"countryCode":166,"cosmosGeoPoint":279,"geoPoint":283,"contacts":284},"City of Hope Comprehensive Cancer Center","RECRUITING","Duarte","91010",{"type":168,"coordinates":280},[281,282],-117.97729,34.13945,{"lat":282,"lon":281},[285,290],{"name":286,"role":287,"phone":288,"phoneExt":33,"email":289},"Site Public Contact","CONTACT","800-826-4673","becomingapatient@coh.org",{"name":291,"role":157,"phone":33,"phoneExt":33,"email":33},"Ibrahim Aldoss",{"facility":293,"status":276,"city":294,"state":244,"zip":295,"country":165,"countryCode":166,"cosmosGeoPoint":296,"geoPoint":300,"contacts":301},"UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care","Irvine","92612",{"type":168,"coordinates":297},[298,299],-117.82311,33.66946,{"lat":299,"lon":298},[302,305],{"name":286,"role":287,"phone":303,"phoneExt":33,"email":304},"877-827-8839","ucstudy@uci.edu",{"name":306,"role":157,"phone":33,"phoneExt":33,"email":33},"Deepa Jeyakumar",{"facility":308,"status":276,"city":309,"state":244,"zip":310,"country":165,"countryCode":166,"cosmosGeoPoint":311,"geoPoint":315,"contacts":316},"UC San Diego Moores Cancer Center","La Jolla","92093",{"type":168,"coordinates":312},[313,314],-117.2742,32.84727,{"lat":314,"lon":313},[317,320],{"name":286,"role":287,"phone":318,"phoneExt":33,"email":319},"858-822-5354","cancercto@ucsd.edu",{"name":321,"role":157,"phone":33,"phoneExt":33,"email":33},"James K. Mangan",{"facility":323,"status":276,"city":324,"state":244,"zip":325,"country":165,"countryCode":166,"cosmosGeoPoint":326,"geoPoint":330,"contacts":331},"UC Irvine Health\u002FChao Family Comprehensive Cancer Center","Orange","92868",{"type":168,"coordinates":327},[328,329],-117.85311,33.78779,{"lat":329,"lon":328},[332,333],{"name":286,"role":287,"phone":303,"phoneExt":33,"email":304},{"name":306,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":335,"status":161,"city":336,"state":244,"zip":337,"country":165,"countryCode":166,"cosmosGeoPoint":338,"geoPoint":342,"contacts":33},"Stanford Cancer Institute Palo Alto","Palo Alto","94304",{"type":168,"coordinates":339},[340,341],-122.14302,37.44188,{"lat":341,"lon":340},{"facility":344,"status":175,"city":345,"state":346,"zip":347,"country":165,"countryCode":166,"cosmosGeoPoint":348,"geoPoint":352,"contacts":33},"Beebe Medical Center","Lewes","Delaware","19958",{"type":168,"coordinates":349},[350,351],-75.13935,38.77456,{"lat":351,"lon":350},{"facility":354,"status":175,"city":355,"state":346,"zip":356,"country":165,"countryCode":166,"cosmosGeoPoint":357,"geoPoint":361,"contacts":33},"Beebe South Coastal Health Campus","Millville","19967",{"type":168,"coordinates":358},[359,360],-75.12324,38.54956,{"lat":360,"lon":359},{"facility":363,"status":175,"city":364,"state":346,"zip":365,"country":165,"countryCode":166,"cosmosGeoPoint":366,"geoPoint":370,"contacts":33},"Delaware Clinical and Laboratory Physicians PA","Newark","19713",{"type":168,"coordinates":367},[368,369],-75.74966,39.68372,{"lat":369,"lon":368},{"facility":372,"status":276,"city":364,"state":346,"zip":365,"country":165,"countryCode":166,"cosmosGeoPoint":373,"geoPoint":375,"contacts":376},"Helen F Graham Cancer Center",{"type":168,"coordinates":374},[368,369],{"lat":369,"lon":368},[377,380],{"name":286,"role":287,"phone":378,"phoneExt":33,"email":379},"302-623-4450","lbarone@christianacare.org",{"name":381,"role":157,"phone":33,"phoneExt":33,"email":33},"Gregory A. Masters",{"facility":383,"status":276,"city":364,"state":346,"zip":365,"country":165,"countryCode":166,"cosmosGeoPoint":384,"geoPoint":386,"contacts":387},"Medical Oncology Hematology Consultants PA",{"type":168,"coordinates":385},[368,369],{"lat":369,"lon":368},[388,389],{"name":286,"role":287,"phone":378,"phoneExt":33,"email":379},{"name":381,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":391,"status":175,"city":364,"state":346,"zip":392,"country":165,"countryCode":166,"cosmosGeoPoint":393,"geoPoint":395,"contacts":33},"Christiana Care Health System-Christiana Hospital","19718",{"type":168,"coordinates":394},[368,369],{"lat":369,"lon":368},{"facility":397,"status":175,"city":398,"state":346,"zip":399,"country":165,"countryCode":166,"cosmosGeoPoint":400,"geoPoint":404,"contacts":33},"Beebe Health Campus","Rehoboth Beach","19971",{"type":168,"coordinates":401},[402,403],-75.07601,38.72095,{"lat":403,"lon":402},{"facility":406,"status":175,"city":407,"state":346,"zip":408,"country":165,"countryCode":166,"cosmosGeoPoint":409,"geoPoint":413,"contacts":33},"TidalHealth Nanticoke \u002F Allen Cancer Center","Seaford","19973",{"type":168,"coordinates":410},[411,412],-75.61104,38.64123,{"lat":412,"lon":411},{"facility":415,"status":175,"city":416,"state":346,"zip":417,"country":165,"countryCode":166,"cosmosGeoPoint":418,"geoPoint":422,"contacts":33},"Christiana Care Health System-Wilmington Hospital","Wilmington","19801",{"type":168,"coordinates":419},[420,421],-75.54659,39.74595,{"lat":421,"lon":420},{"facility":424,"status":276,"city":425,"state":426,"zip":427,"country":165,"countryCode":166,"cosmosGeoPoint":428,"geoPoint":432,"contacts":433},"MedStar Georgetown University Hospital","Washington D.C.","District of Columbia","20007",{"type":168,"coordinates":429},[430,431],-77.03637,38.89511,{"lat":431,"lon":430},[434,436],{"name":286,"role":287,"phone":435,"phoneExt":33,"email":33},"202-444-2223",{"name":437,"role":157,"phone":33,"phoneExt":33,"email":33},"Kimberley Doucette",{"facility":439,"status":175,"city":440,"state":441,"zip":442,"country":165,"countryCode":166,"cosmosGeoPoint":443,"geoPoint":447,"contacts":33},"Holy Cross Hospital","Fort Lauderdale","Florida","33308",{"type":168,"coordinates":444},[445,446],-80.14338,26.12231,{"lat":446,"lon":445},{"facility":449,"status":276,"city":450,"state":441,"zip":451,"country":165,"countryCode":166,"cosmosGeoPoint":452,"geoPoint":456,"contacts":457},"Jupiter Medical Center","Jupiter","33458",{"type":168,"coordinates":453},[454,455],-80.09421,26.93422,{"lat":455,"lon":454},[458,461],{"name":286,"role":287,"phone":459,"phoneExt":33,"email":460},"561-263-5791","clinicaltrials@jupitermed.com",{"name":462,"role":157,"phone":33,"phoneExt":33,"email":33},"Ryan H. Devine",{"facility":464,"status":276,"city":465,"state":466,"zip":467,"country":165,"countryCode":166,"cosmosGeoPoint":468,"geoPoint":472,"contacts":473},"Emory University Hospital\u002FWinship Cancer Institute","Atlanta","Georgia","30322",{"type":168,"coordinates":469},[470,471],-84.38798,33.749,{"lat":471,"lon":470},[474,476],{"name":286,"role":287,"phone":475,"phoneExt":33,"email":33},"404-778-1868",{"name":477,"role":157,"phone":33,"phoneExt":33,"email":33},"William G. Blum",{"facility":479,"status":276,"city":465,"state":466,"zip":480,"country":165,"countryCode":166,"cosmosGeoPoint":481,"geoPoint":483,"contacts":484},"Emory Saint Joseph's Hospital","30342",{"type":168,"coordinates":482},[470,471],{"lat":471,"lon":470},[485,487],{"name":286,"role":287,"phone":486,"phoneExt":33,"email":33},"404-851-7115",{"name":477,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":489,"status":175,"city":490,"state":491,"zip":492,"country":165,"countryCode":166,"cosmosGeoPoint":493,"geoPoint":497,"contacts":33},"Saint Luke's Cancer Institute - Boise","Boise","Idaho","83712",{"type":168,"coordinates":494},[495,496],-116.20345,43.6135,{"lat":496,"lon":495},{"facility":499,"status":175,"city":500,"state":491,"zip":501,"country":165,"countryCode":166,"cosmosGeoPoint":502,"geoPoint":506,"contacts":33},"Saint Luke's Cancer Institute - Fruitland","Fruitland","83619",{"type":168,"coordinates":503},[504,505],-116.91655,44.00766,{"lat":505,"lon":504},{"facility":508,"status":175,"city":509,"state":491,"zip":510,"country":165,"countryCode":166,"cosmosGeoPoint":511,"geoPoint":515,"contacts":33},"Saint Luke's Cancer Institute - Meridian","Meridian","83642",{"type":168,"coordinates":512},[513,514],-116.39151,43.61211,{"lat":514,"lon":513},{"facility":517,"status":276,"city":518,"state":491,"zip":519,"country":165,"countryCode":166,"cosmosGeoPoint":520,"geoPoint":524,"contacts":525},"Saint Alphonsus Cancer Care Center-Nampa","Nampa","83687",{"type":168,"coordinates":521},[522,523],-116.56346,43.54072,{"lat":523,"lon":522},[526,529],{"name":286,"role":287,"phone":527,"phoneExt":33,"email":528},"406-969-6060","mccinfo@mtcancer.org",{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},"Christopher M. Reynolds",{"facility":532,"status":175,"city":518,"state":491,"zip":519,"country":165,"countryCode":166,"cosmosGeoPoint":533,"geoPoint":535,"contacts":33},"Saint Luke's Cancer Institute - Nampa",{"type":168,"coordinates":534},[522,523],{"lat":523,"lon":522},{"facility":537,"status":175,"city":538,"state":491,"zip":539,"country":165,"countryCode":166,"cosmosGeoPoint":540,"geoPoint":544,"contacts":33},"Saint Luke's Cancer Institute - Twin Falls","Twin Falls","83301",{"type":168,"coordinates":541},[542,543],-114.46087,42.56297,{"lat":543,"lon":542},{"facility":546,"status":175,"city":547,"state":548,"zip":549,"country":165,"countryCode":166,"cosmosGeoPoint":550,"geoPoint":554,"contacts":33},"OSF Saint Anthony's Health Center","Alton","Illinois","62002",{"type":168,"coordinates":551},[552,553],-90.18428,38.8906,{"lat":553,"lon":552},{"facility":556,"status":175,"city":557,"state":548,"zip":558,"country":165,"countryCode":166,"cosmosGeoPoint":559,"geoPoint":563,"contacts":33},"Illinois CancerCare-Bloomington","Bloomington","61704",{"type":168,"coordinates":560},[561,562],-88.99369,40.4842,{"lat":562,"lon":561},{"facility":565,"status":175,"city":566,"state":548,"zip":567,"country":165,"countryCode":166,"cosmosGeoPoint":568,"geoPoint":572,"contacts":33},"Loyola Center for Health at Burr Ridge","Burr Ridge","60527",{"type":168,"coordinates":569},[570,571],-87.91839,41.74892,{"lat":571,"lon":570},{"facility":574,"status":175,"city":575,"state":548,"zip":576,"country":165,"countryCode":166,"cosmosGeoPoint":577,"geoPoint":581,"contacts":33},"Illinois CancerCare-Canton","Canton","61520",{"type":168,"coordinates":578},[579,580],-90.03512,40.55809,{"lat":580,"lon":579},{"facility":583,"status":175,"city":584,"state":548,"zip":585,"country":165,"countryCode":166,"cosmosGeoPoint":586,"geoPoint":590,"contacts":33},"Memorial Hospital of Carbondale","Carbondale","62902",{"type":168,"coordinates":587},[588,589],-89.21675,37.72727,{"lat":589,"lon":588},{"facility":592,"status":175,"city":593,"state":548,"zip":594,"country":165,"countryCode":166,"cosmosGeoPoint":595,"geoPoint":599,"contacts":33},"SIH Cancer Institute","Carterville","62918",{"type":168,"coordinates":596},[597,598],-89.0773,37.76005,{"lat":598,"lon":597},{"facility":601,"status":175,"city":602,"state":548,"zip":603,"country":165,"countryCode":166,"cosmosGeoPoint":604,"geoPoint":608,"contacts":33},"Illinois CancerCare-Carthage","Carthage","62321",{"type":168,"coordinates":605},[606,607],-91.13625,40.41643,{"lat":607,"lon":606},{"facility":610,"status":175,"city":611,"state":548,"zip":612,"country":165,"countryCode":166,"cosmosGeoPoint":613,"geoPoint":617,"contacts":33},"Centralia Oncology Clinic","Centralia","62801",{"type":168,"coordinates":614},[615,616],-89.1334,38.52505,{"lat":616,"lon":615},{"facility":619,"status":276,"city":620,"state":548,"zip":621,"country":165,"countryCode":166,"cosmosGeoPoint":622,"geoPoint":626,"contacts":627},"Northwestern University","Chicago","60611",{"type":168,"coordinates":623},[624,625],-87.65005,41.85003,{"lat":625,"lon":624},[628,631],{"name":286,"role":287,"phone":629,"phoneExt":33,"email":630},"312-695-1301","cancer@northwestern.edu",{"name":632,"role":157,"phone":33,"phoneExt":33,"email":33},"Shira N. Dinner",{"facility":634,"status":276,"city":620,"state":548,"zip":635,"country":165,"countryCode":166,"cosmosGeoPoint":636,"geoPoint":638,"contacts":639},"University of Illinois","60612",{"type":168,"coordinates":637},[624,625],{"lat":625,"lon":624},[640,642],{"name":286,"role":287,"phone":641,"phoneExt":33,"email":33},"312-355-3046",{"name":643,"role":157,"phone":33,"phoneExt":33,"email":33},"John G. Quigley",{"facility":645,"status":276,"city":620,"state":548,"zip":646,"country":165,"countryCode":166,"cosmosGeoPoint":647,"geoPoint":649,"contacts":650},"University of Chicago Comprehensive Cancer Center","60637",{"type":168,"coordinates":648},[624,625],{"lat":625,"lon":624},[651,654],{"name":286,"role":287,"phone":652,"phoneExt":33,"email":653},"773-702-8222","cancerclinicaltrials@bsd.uchicago.edu",{"name":655,"role":157,"phone":33,"phoneExt":33,"email":33},"Wendy Stock",{"facility":657,"status":276,"city":658,"state":548,"zip":659,"country":165,"countryCode":166,"cosmosGeoPoint":660,"geoPoint":664,"contacts":665},"Cancer Care Specialists of Illinois - Decatur","Decatur","62526",{"type":168,"coordinates":661},[662,663],-88.9548,39.84031,{"lat":663,"lon":662},[666,669],{"name":286,"role":287,"phone":667,"phoneExt":33,"email":668},"217-876-4762","morganthaler.jodi@mhsil.com",{"name":670,"role":157,"phone":33,"phoneExt":33,"email":33},"Bryan A. Faller",{"facility":672,"status":175,"city":658,"state":548,"zip":659,"country":165,"countryCode":166,"cosmosGeoPoint":673,"geoPoint":675,"contacts":33},"Decatur Memorial Hospital",{"type":168,"coordinates":674},[662,663],{"lat":663,"lon":662},{"facility":677,"status":175,"city":678,"state":548,"zip":679,"country":165,"countryCode":166,"cosmosGeoPoint":680,"geoPoint":684,"contacts":33},"Illinois CancerCare-Dixon","Dixon","61021",{"type":168,"coordinates":681},[682,683],-89.47955,41.83892,{"lat":683,"lon":682},{"facility":686,"status":276,"city":687,"state":548,"zip":688,"country":165,"countryCode":166,"cosmosGeoPoint":689,"geoPoint":693,"contacts":694},"Crossroads Cancer Center","Effingham","62401",{"type":168,"coordinates":690},[691,692],-88.54338,39.12004,{"lat":692,"lon":691},[695,696],{"name":286,"role":287,"phone":667,"phoneExt":33,"email":668},{"name":670,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":698,"status":175,"city":699,"state":548,"zip":700,"country":165,"countryCode":166,"cosmosGeoPoint":701,"geoPoint":705,"contacts":33},"Illinois CancerCare-Eureka","Eureka","61530",{"type":168,"coordinates":702},[703,704],-89.27286,40.72143,{"lat":704,"lon":703},{"facility":707,"status":276,"city":708,"state":548,"zip":709,"country":165,"countryCode":166,"cosmosGeoPoint":710,"geoPoint":714,"contacts":715},"NorthShore University HealthSystem-Evanston Hospital","Evanston","60201",{"type":168,"coordinates":711},[712,713],-87.69006,42.04114,{"lat":713,"lon":712},[716,718],{"name":286,"role":287,"phone":717,"phoneExt":33,"email":33},"847-570-2109",{"name":719,"role":157,"phone":33,"phoneExt":33,"email":33},"Amy Y. Wang",{"facility":721,"status":175,"city":722,"state":548,"zip":723,"country":165,"countryCode":166,"cosmosGeoPoint":724,"geoPoint":728,"contacts":33},"Illinois CancerCare-Galesburg","Galesburg","61401",{"type":168,"coordinates":725},[726,727],-90.37124,40.94782,{"lat":727,"lon":726},{"facility":730,"status":175,"city":722,"state":548,"zip":723,"country":165,"countryCode":166,"cosmosGeoPoint":731,"geoPoint":733,"contacts":33},"Western Illinois Cancer Treatment Center",{"type":168,"coordinates":732},[726,727],{"lat":727,"lon":726},{"facility":735,"status":276,"city":736,"state":548,"zip":737,"country":165,"countryCode":166,"cosmosGeoPoint":738,"geoPoint":742,"contacts":743},"NorthShore University HealthSystem-Glenbrook Hospital","Glenview","60026",{"type":168,"coordinates":739},[740,741],-87.78784,42.06975,{"lat":741,"lon":740},[744,745],{"name":286,"role":287,"phone":717,"phoneExt":33,"email":33},{"name":719,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":747,"status":276,"city":748,"state":548,"zip":749,"country":165,"countryCode":166,"cosmosGeoPoint":750,"geoPoint":754,"contacts":755},"NorthShore University HealthSystem-Highland Park Hospital","Highland Park","60035",{"type":168,"coordinates":751},[752,753],-87.80034,42.18169,{"lat":753,"lon":752},[756,757],{"name":286,"role":287,"phone":717,"phoneExt":33,"email":33},{"name":719,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":759,"status":175,"city":760,"state":548,"zip":761,"country":165,"countryCode":166,"cosmosGeoPoint":762,"geoPoint":766,"contacts":33},"Loyola Medicine Homer Glen","Homer Glen","60491",{"type":168,"coordinates":763},[764,765],-87.93811,41.60003,{"lat":765,"lon":764},{"facility":768,"status":175,"city":769,"state":548,"zip":770,"country":165,"countryCode":166,"cosmosGeoPoint":771,"geoPoint":775,"contacts":33},"Illinois CancerCare-Kewanee Clinic","Kewanee","61443",{"type":168,"coordinates":772},[773,774],-89.92483,41.24559,{"lat":774,"lon":773},{"facility":777,"status":161,"city":778,"state":548,"zip":779,"country":165,"countryCode":166,"cosmosGeoPoint":780,"geoPoint":784,"contacts":33},"Northwestern Medicine Lake Forest Hospital","Lake Forest","60045",{"type":168,"coordinates":781},[782,783],-87.84063,42.25863,{"lat":783,"lon":782},{"facility":786,"status":175,"city":787,"state":548,"zip":788,"country":165,"countryCode":166,"cosmosGeoPoint":789,"geoPoint":793,"contacts":33},"Illinois CancerCare-Macomb","Macomb","61455",{"type":168,"coordinates":790},[791,792],-90.6718,40.45921,{"lat":792,"lon":791},{"facility":795,"status":276,"city":796,"state":548,"zip":797,"country":165,"countryCode":166,"cosmosGeoPoint":798,"geoPoint":802,"contacts":803},"Loyola University Medical Center","Maywood","60153",{"type":168,"coordinates":799},[800,801],-87.84312,41.8792,{"lat":801,"lon":800},[804,806],{"name":286,"role":287,"phone":805,"phoneExt":33,"email":33},"708-226-4357",{"name":807,"role":157,"phone":33,"phoneExt":33,"email":33},"Stephanie B. Tsai",{"facility":809,"status":175,"city":810,"state":548,"zip":811,"country":165,"countryCode":166,"cosmosGeoPoint":812,"geoPoint":816,"contacts":33},"Marjorie Weinberg Cancer Center at Loyola-Gottlieb","Melrose Park","60160",{"type":168,"coordinates":813},[814,815],-87.85673,41.90059,{"lat":815,"lon":814},{"facility":818,"status":175,"city":819,"state":548,"zip":820,"country":165,"countryCode":166,"cosmosGeoPoint":821,"geoPoint":825,"contacts":33},"SSM Health Good Samaritan","Mount Vernon","62864",{"type":168,"coordinates":822},[823,824],-88.90312,38.31727,{"lat":824,"lon":823},{"facility":827,"status":276,"city":828,"state":548,"zip":829,"country":165,"countryCode":166,"cosmosGeoPoint":830,"geoPoint":834,"contacts":835},"UC Comprehensive Cancer Center at Silver Cross","New Lenox","60451",{"type":168,"coordinates":831},[832,833],-87.96561,41.51198,{"lat":833,"lon":832},[836,837],{"name":286,"role":287,"phone":652,"phoneExt":33,"email":653},{"name":655,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":839,"status":175,"city":840,"state":548,"zip":841,"country":165,"countryCode":166,"cosmosGeoPoint":842,"geoPoint":846,"contacts":33},"Cancer Care Center of O'Fallon","O'Fallon","62269",{"type":168,"coordinates":843},[844,845],-89.91121,38.59227,{"lat":845,"lon":844},{"facility":848,"status":276,"city":849,"state":548,"zip":850,"country":165,"countryCode":166,"cosmosGeoPoint":851,"geoPoint":855,"contacts":856},"University of Chicago Medicine-Orland Park","Orland Park","60462",{"type":168,"coordinates":852},[853,854],-87.85394,41.63031,{"lat":854,"lon":853},[857,858],{"name":286,"role":287,"phone":652,"phoneExt":33,"email":653},{"name":655,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":860,"status":175,"city":861,"state":548,"zip":862,"country":165,"countryCode":166,"cosmosGeoPoint":863,"geoPoint":867,"contacts":33},"Illinois CancerCare-Ottawa Clinic","Ottawa","61350",{"type":168,"coordinates":864},[865,866],-88.84258,41.34559,{"lat":866,"lon":865},{"facility":869,"status":175,"city":870,"state":548,"zip":871,"country":165,"countryCode":166,"cosmosGeoPoint":872,"geoPoint":876,"contacts":33},"Illinois CancerCare-Pekin","Pekin","61554",{"type":168,"coordinates":873},[874,875],-89.64066,40.56754,{"lat":875,"lon":874},{"facility":878,"status":175,"city":870,"state":548,"zip":871,"country":165,"countryCode":166,"cosmosGeoPoint":879,"geoPoint":881,"contacts":33},"OSF Saint Francis Radiation Oncology at Pekin",{"type":168,"coordinates":880},[874,875],{"lat":875,"lon":874},{"facility":883,"status":276,"city":884,"state":548,"zip":885,"country":165,"countryCode":166,"cosmosGeoPoint":886,"geoPoint":890,"contacts":891},"Illinois CancerCare-Peoria","Peoria","61615",{"type":168,"coordinates":887},[888,889],-89.58899,40.69365,{"lat":889,"lon":888},[892,895],{"name":286,"role":287,"phone":893,"phoneExt":33,"email":894},"309-243-3605","andersonj@illinoiscancercare.com",{"name":670,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":897,"status":175,"city":884,"state":548,"zip":885,"country":165,"countryCode":166,"cosmosGeoPoint":898,"geoPoint":900,"contacts":33},"OSF Saint Francis Radiation Oncology at Peoria Cancer Center",{"type":168,"coordinates":899},[888,889],{"lat":889,"lon":888},{"facility":902,"status":175,"city":884,"state":548,"zip":903,"country":165,"countryCode":166,"cosmosGeoPoint":904,"geoPoint":906,"contacts":33},"Methodist Medical Center of Illinois","61636",{"type":168,"coordinates":905},[888,889],{"lat":889,"lon":888},{"facility":908,"status":175,"city":884,"state":548,"zip":909,"country":165,"countryCode":166,"cosmosGeoPoint":910,"geoPoint":912,"contacts":33},"OSF Saint Francis Medical Center","61637",{"type":168,"coordinates":911},[888,889],{"lat":889,"lon":888},{"facility":914,"status":175,"city":915,"state":548,"zip":916,"country":165,"countryCode":166,"cosmosGeoPoint":917,"geoPoint":921,"contacts":33},"Illinois CancerCare-Peru","Peru","61354",{"type":168,"coordinates":918},[919,920],-89.12897,41.32753,{"lat":920,"lon":919},{"facility":923,"status":175,"city":915,"state":548,"zip":916,"country":165,"countryCode":166,"cosmosGeoPoint":924,"geoPoint":926,"contacts":33},"Valley Radiation Oncology",{"type":168,"coordinates":925},[919,920],{"lat":920,"lon":919},{"facility":928,"status":175,"city":929,"state":548,"zip":930,"country":165,"countryCode":166,"cosmosGeoPoint":931,"geoPoint":935,"contacts":33},"Illinois CancerCare-Princeton","Princeton","61356",{"type":168,"coordinates":932},[933,934],-89.46481,41.36809,{"lat":934,"lon":933},{"facility":937,"status":175,"city":938,"state":548,"zip":939,"country":165,"countryCode":166,"cosmosGeoPoint":940,"geoPoint":944,"contacts":33},"Southern Illinois University School of Medicine","Springfield","62702",{"type":168,"coordinates":941},[942,943],-89.64371,39.80172,{"lat":943,"lon":942},{"facility":946,"status":175,"city":938,"state":548,"zip":939,"country":165,"countryCode":166,"cosmosGeoPoint":947,"geoPoint":949,"contacts":33},"Springfield Clinic",{"type":168,"coordinates":948},[942,943],{"lat":943,"lon":942},{"facility":951,"status":175,"city":938,"state":548,"zip":952,"country":165,"countryCode":166,"cosmosGeoPoint":953,"geoPoint":955,"contacts":33},"Springfield Memorial Hospital","62781",{"type":168,"coordinates":954},[942,943],{"lat":943,"lon":942},{"facility":957,"status":175,"city":958,"state":548,"zip":959,"country":165,"countryCode":166,"cosmosGeoPoint":960,"geoPoint":964,"contacts":33},"Illinois CancerCare - Washington","Washington","61571",{"type":168,"coordinates":961},[962,963],-89.40731,40.70365,{"lat":963,"lon":962},{"facility":966,"status":175,"city":967,"state":968,"zip":969,"country":165,"countryCode":166,"cosmosGeoPoint":970,"geoPoint":974,"contacts":33},"Central Care Cancer Center - Garden City","Garden City","Kansas","67846",{"type":168,"coordinates":971},[972,973],-100.87266,37.97169,{"lat":973,"lon":972},{"facility":976,"status":175,"city":977,"state":968,"zip":978,"country":165,"countryCode":166,"cosmosGeoPoint":979,"geoPoint":983,"contacts":33},"Central Care Cancer Center - Great Bend","Great Bend","67530",{"type":168,"coordinates":980},[981,982],-98.76481,38.36446,{"lat":982,"lon":981},{"facility":985,"status":276,"city":986,"state":968,"zip":987,"country":165,"countryCode":166,"cosmosGeoPoint":988,"geoPoint":992,"contacts":993},"University of Kansas Cancer Center","Kansas City","66160",{"type":168,"coordinates":989},[990,991],-94.62746,39.11417,{"lat":991,"lon":990},[994,997],{"name":286,"role":287,"phone":995,"phoneExt":33,"email":996},"913-588-3671","KUCC_Navigation@kumc.edu",{"name":998,"role":157,"phone":33,"phoneExt":33,"email":33},"Kenneth Byrd",{"facility":1000,"status":276,"city":1001,"state":968,"zip":1002,"country":165,"countryCode":166,"cosmosGeoPoint":1003,"geoPoint":1007,"contacts":1008},"University of Kansas Hospital-Westwood Cancer Center","Westwood","66205",{"type":168,"coordinates":1004},[1005,1006],-94.6169,39.04056,{"lat":1006,"lon":1005},[1009,1010],{"name":286,"role":287,"phone":995,"phoneExt":33,"email":996},{"name":998,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1012,"status":161,"city":1013,"state":1014,"zip":1015,"country":165,"countryCode":166,"cosmosGeoPoint":1016,"geoPoint":1020,"contacts":33},"Ochsner Medical Center Jefferson","New Orleans","Louisiana","70121",{"type":168,"coordinates":1017},[1018,1019],-90.07507,29.95465,{"lat":1019,"lon":1018},{"facility":1022,"status":161,"city":1023,"state":1024,"zip":1025,"country":165,"countryCode":166,"cosmosGeoPoint":1026,"geoPoint":1030,"contacts":33},"University of Maryland\u002FGreenebaum Cancer Center","Baltimore","Maryland","21201",{"type":168,"coordinates":1027},[1028,1029],-76.61219,39.29038,{"lat":1029,"lon":1028},{"facility":1032,"status":175,"city":938,"state":1033,"zip":1034,"country":165,"countryCode":166,"cosmosGeoPoint":1035,"geoPoint":1039,"contacts":33},"Mercy Medical Center","Massachusetts","01104",{"type":168,"coordinates":1036},[1037,1038],-72.58981,42.10148,{"lat":1038,"lon":1037},{"facility":1041,"status":276,"city":1042,"state":1043,"zip":1044,"country":165,"countryCode":166,"cosmosGeoPoint":1045,"geoPoint":1049,"contacts":1050},"Trinity Health Saint Joseph Mercy Hospital Ann Arbor","Ann Arbor","Michigan","48106",{"type":168,"coordinates":1046},[1047,1048],-83.74088,42.27756,{"lat":1048,"lon":1047},[1051,1054],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},"734-712-7251","MCRCwebsitecontactform@stjoeshealth.org",{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1056,"status":276,"city":1057,"state":1043,"zip":1058,"country":165,"countryCode":166,"cosmosGeoPoint":1059,"geoPoint":1063,"contacts":1064},"Trinity Health IHA Medical Group Hematology Oncology - Brighton","Brighton","48114",{"type":168,"coordinates":1060},[1061,1062],-83.78022,42.52948,{"lat":1062,"lon":1061},[1065,1066],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1068,"status":276,"city":1057,"state":1043,"zip":1058,"country":165,"countryCode":166,"cosmosGeoPoint":1069,"geoPoint":1071,"contacts":1072},"Trinity Health Medical Center - Brighton",{"type":168,"coordinates":1070},[1061,1062],{"lat":1062,"lon":1061},[1073,1074],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1076,"status":276,"city":575,"state":1043,"zip":1077,"country":165,"countryCode":166,"cosmosGeoPoint":1078,"geoPoint":1082,"contacts":1083},"Trinity Health IHA Medical Group Hematology Oncology - Canton","48188",{"type":168,"coordinates":1079},[1080,1081],-83.48216,42.30865,{"lat":1081,"lon":1080},[1084,1085],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1087,"status":276,"city":575,"state":1043,"zip":1077,"country":165,"countryCode":166,"cosmosGeoPoint":1088,"geoPoint":1090,"contacts":1091},"Trinity Health Medical Center - Canton",{"type":168,"coordinates":1089},[1080,1081],{"lat":1081,"lon":1080},[1092,1093],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1095,"status":175,"city":1096,"state":1043,"zip":1097,"country":165,"countryCode":166,"cosmosGeoPoint":1098,"geoPoint":1102,"contacts":33},"Caro Cancer Center","Caro","48723",{"type":168,"coordinates":1099},[1100,1101],-83.39885,43.49073,{"lat":1101,"lon":1100},{"facility":1104,"status":276,"city":1105,"state":1043,"zip":1106,"country":165,"countryCode":166,"cosmosGeoPoint":1107,"geoPoint":1111,"contacts":1112},"Chelsea Hospital","Chelsea","48118",{"type":168,"coordinates":1108},[1109,1110],-84.02181,42.31807,{"lat":1110,"lon":1109},[1113,1114],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1116,"status":276,"city":1105,"state":1043,"zip":1106,"country":165,"countryCode":166,"cosmosGeoPoint":1117,"geoPoint":1119,"contacts":1120},"Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital",{"type":168,"coordinates":1118},[1109,1110],{"lat":1110,"lon":1109},[1121,1122],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1124,"status":175,"city":1125,"state":1043,"zip":1126,"country":165,"countryCode":166,"cosmosGeoPoint":1127,"geoPoint":1131,"contacts":33},"Hematology Oncology Consultants-Clarkston","Clarkston","48346",{"type":168,"coordinates":1128},[1129,1130],-83.41883,42.73586,{"lat":1130,"lon":1129},{"facility":1133,"status":175,"city":1125,"state":1043,"zip":1126,"country":165,"countryCode":166,"cosmosGeoPoint":1134,"geoPoint":1136,"contacts":33},"Newland Medical Associates-Clarkston",{"type":168,"coordinates":1135},[1129,1130],{"lat":1130,"lon":1129},{"facility":1138,"status":276,"city":1139,"state":1043,"zip":1140,"country":165,"countryCode":166,"cosmosGeoPoint":1141,"geoPoint":1145,"contacts":1146},"Henry Ford Health Saint John Hospital","Detroit","48236",{"type":168,"coordinates":1142},[1143,1144],-83.04575,42.33143,{"lat":1144,"lon":1143},[1147,1150],{"name":286,"role":287,"phone":1148,"phoneExt":33,"email":1149},"313-343-3166","Kkeenan1@hfhs.org",{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1152,"status":276,"city":1153,"state":1043,"zip":1154,"country":165,"countryCode":166,"cosmosGeoPoint":33,"geoPoint":33,"contacts":1155},"Henry Ford River District Hospital","East China Township","48054",[1156,1158],{"name":286,"role":287,"phone":1148,"phoneExt":33,"email":1157},"kforman1@hfhs.org",{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1160,"status":276,"city":1161,"state":1043,"zip":1162,"country":165,"countryCode":166,"cosmosGeoPoint":1163,"geoPoint":1167,"contacts":1168},"Cancer Hematology Centers - Flint","Flint","48503",{"type":168,"coordinates":1164},[1165,1166],-83.68746,43.01253,{"lat":1166,"lon":1165},[1169,1172],{"name":286,"role":287,"phone":1170,"phoneExt":33,"email":1171},"810-762-8038","wstrong@ghci.org",{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1174,"status":175,"city":1161,"state":1043,"zip":1162,"country":165,"countryCode":166,"cosmosGeoPoint":1175,"geoPoint":1177,"contacts":33},"Genesee Hematology Oncology PC",{"type":168,"coordinates":1176},[1165,1166],{"lat":1166,"lon":1165},{"facility":1179,"status":276,"city":1161,"state":1043,"zip":1162,"country":165,"countryCode":166,"cosmosGeoPoint":1180,"geoPoint":1182,"contacts":1183},"Genesys Hurley Cancer Institute",{"type":168,"coordinates":1181},[1165,1166],{"lat":1166,"lon":1165},[1184,1185],{"name":286,"role":287,"phone":1170,"phoneExt":33,"email":1171},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1187,"status":276,"city":1161,"state":1043,"zip":1162,"country":165,"countryCode":166,"cosmosGeoPoint":1188,"geoPoint":1190,"contacts":1191},"Hurley Medical Center",{"type":168,"coordinates":1189},[1165,1166],{"lat":1166,"lon":1165},[1192,1193],{"name":286,"role":287,"phone":1170,"phoneExt":33,"email":1171},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1195,"status":276,"city":1196,"state":1043,"zip":1140,"country":165,"countryCode":166,"cosmosGeoPoint":1197,"geoPoint":1201,"contacts":1202},"Henry Ford Saint John Hospital - Academic","Grosse Pointe Woods",{"type":168,"coordinates":1198},[1199,1200],-82.90686,42.44365,{"lat":1200,"lon":1199},[1203,1204],{"name":286,"role":287,"phone":1148,"phoneExt":33,"email":1157},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1206,"status":175,"city":1196,"state":1043,"zip":1140,"country":165,"countryCode":166,"cosmosGeoPoint":1207,"geoPoint":1209,"contacts":33},"Henry Ford Saint John Hospital - Breast",{"type":168,"coordinates":1208},[1199,1200],{"lat":1200,"lon":1199},{"facility":1211,"status":276,"city":1196,"state":1043,"zip":1140,"country":165,"countryCode":166,"cosmosGeoPoint":1212,"geoPoint":1214,"contacts":1215},"Henry Ford Saint John Hospital - Van Elslander",{"type":168,"coordinates":1213},[1199,1200],{"lat":1200,"lon":1199},[1216,1217],{"name":286,"role":287,"phone":1148,"phoneExt":33,"email":1157},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1219,"status":175,"city":1220,"state":1043,"zip":1221,"country":165,"countryCode":166,"cosmosGeoPoint":1222,"geoPoint":1226,"contacts":33},"University of Michigan Health - Sparrow Lansing","Lansing","48912",{"type":168,"coordinates":1223},[1224,1225],-84.55553,42.73253,{"lat":1225,"lon":1224},{"facility":1228,"status":175,"city":1229,"state":1043,"zip":1230,"country":165,"countryCode":166,"cosmosGeoPoint":1231,"geoPoint":1235,"contacts":33},"Hope Cancer Clinic","Livonia","48154",{"type":168,"coordinates":1232},[1233,1234],-83.35271,42.36837,{"lat":1234,"lon":1233},{"facility":1237,"status":276,"city":1229,"state":1043,"zip":1230,"country":165,"countryCode":166,"cosmosGeoPoint":1238,"geoPoint":1240,"contacts":1241},"Trinity Health Saint Mary Mercy Livonia Hospital",{"type":168,"coordinates":1239},[1233,1234],{"lat":1234,"lon":1233},[1242,1243],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1245,"status":276,"city":787,"state":1043,"zip":1246,"country":165,"countryCode":166,"cosmosGeoPoint":1247,"geoPoint":1251,"contacts":1252},"Henry Ford Saint John Hospital - Macomb Medical","48044",{"type":168,"coordinates":1248},[1249,1250],-82.95909,42.70087,{"lat":1250,"lon":1249},[1253,1254],{"name":286,"role":287,"phone":1148,"phoneExt":33,"email":1157},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1256,"status":175,"city":787,"state":1043,"zip":1246,"country":165,"countryCode":166,"cosmosGeoPoint":1257,"geoPoint":1259,"contacts":33},"Henry Ford Warren Hospital - Breast Macomb",{"type":168,"coordinates":1258},[1249,1250],{"lat":1250,"lon":1249},{"facility":1261,"status":175,"city":1262,"state":1043,"zip":1263,"country":165,"countryCode":166,"cosmosGeoPoint":1264,"geoPoint":1268,"contacts":33},"Saint Mary's Oncology\u002FHematology Associates of Marlette","Marlette","48453",{"type":168,"coordinates":1265},[1266,1267],-83.08022,43.32697,{"lat":1267,"lon":1266},{"facility":1270,"status":175,"city":1271,"state":1043,"zip":1272,"country":165,"countryCode":166,"cosmosGeoPoint":1273,"geoPoint":1277,"contacts":33},"Hope Cancer Center","Pontiac","48341",{"type":168,"coordinates":1274},[1275,1276],-83.29105,42.63892,{"lat":1276,"lon":1275},{"facility":1279,"status":175,"city":1271,"state":1043,"zip":1272,"country":165,"countryCode":166,"cosmosGeoPoint":1280,"geoPoint":1282,"contacts":33},"Michigan Healthcare Professionals Pontiac",{"type":168,"coordinates":1281},[1275,1276],{"lat":1276,"lon":1275},{"facility":1284,"status":175,"city":1271,"state":1043,"zip":1272,"country":165,"countryCode":166,"cosmosGeoPoint":1285,"geoPoint":1287,"contacts":33},"Newland Medical Associates-Pontiac",{"type":168,"coordinates":1286},[1275,1276],{"lat":1276,"lon":1275},{"facility":1289,"status":276,"city":1271,"state":1043,"zip":1272,"country":165,"countryCode":166,"cosmosGeoPoint":1290,"geoPoint":1292,"contacts":1293},"Trinity Health Saint Joseph Mercy Oakland Hospital",{"type":168,"coordinates":1291},[1275,1276],{"lat":1276,"lon":1275},[1294,1295],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1297,"status":175,"city":1298,"state":1043,"zip":1299,"country":165,"countryCode":166,"cosmosGeoPoint":1300,"geoPoint":1304,"contacts":33},"Henry Ford Rochester Hospital","Rochester Hills","48309",{"type":168,"coordinates":1301},[1302,1303],-83.14993,42.65837,{"lat":1303,"lon":1302},{"facility":1306,"status":276,"city":1307,"state":1043,"zip":1308,"country":165,"countryCode":166,"cosmosGeoPoint":1309,"geoPoint":1313,"contacts":1314},"MyMichigan Medical Center Saginaw","Saginaw","48601",{"type":168,"coordinates":1310},[1311,1312],-83.95081,43.41947,{"lat":1312,"lon":1311},[1315,1316],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1318,"status":175,"city":1307,"state":1043,"zip":1319,"country":165,"countryCode":166,"cosmosGeoPoint":1320,"geoPoint":1322,"contacts":33},"Oncology Hematology Associates of Saginaw Valley PC","48604",{"type":168,"coordinates":1321},[1311,1312],{"lat":1312,"lon":1311},{"facility":1324,"status":175,"city":1325,"state":1043,"zip":1326,"country":165,"countryCode":166,"cosmosGeoPoint":1327,"geoPoint":1331,"contacts":33},"Bhadresh Nayak MD PC-Sterling Heights","Sterling Heights","48312",{"type":168,"coordinates":1328},[1329,1330],-83.0302,42.58031,{"lat":1330,"lon":1329},{"facility":1333,"status":276,"city":1334,"state":1043,"zip":1335,"country":165,"countryCode":166,"cosmosGeoPoint":1336,"geoPoint":1340,"contacts":1341},"MyMichigan Medical Center Tawas","Tawas City","48764",{"type":168,"coordinates":1337},[1338,1339],-83.5147,44.26946,{"lat":1339,"lon":1338},[1342,1343],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1345,"status":175,"city":1346,"state":1043,"zip":1347,"country":165,"countryCode":166,"cosmosGeoPoint":1348,"geoPoint":1352,"contacts":33},"Advanced Breast Care Center PLLC","Warren","48088",{"type":168,"coordinates":1349},[1350,1351],-83.01304,42.49044,{"lat":1351,"lon":1350},{"facility":1354,"status":276,"city":1346,"state":1043,"zip":1355,"country":165,"countryCode":166,"cosmosGeoPoint":1356,"geoPoint":1358,"contacts":1359},"Henry Ford Health Warren Hospital","48093",{"type":168,"coordinates":1357},[1350,1351],{"lat":1351,"lon":1350},[1360,1361],{"name":286,"role":287,"phone":1148,"phoneExt":33,"email":1157},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1363,"status":175,"city":1346,"state":1043,"zip":1355,"country":165,"countryCode":166,"cosmosGeoPoint":1364,"geoPoint":1366,"contacts":33},"Henry Ford Madison Heights Hospital - Breast",{"type":168,"coordinates":1365},[1350,1351],{"lat":1351,"lon":1350},{"facility":1368,"status":276,"city":1346,"state":1043,"zip":1355,"country":165,"countryCode":166,"cosmosGeoPoint":1369,"geoPoint":1371,"contacts":1372},"Henry Ford Warren Hospital - GLCMS",{"type":168,"coordinates":1370},[1350,1351],{"lat":1351,"lon":1350},[1373,1374],{"name":286,"role":287,"phone":1148,"phoneExt":33,"email":1157},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1376,"status":175,"city":1346,"state":1043,"zip":1355,"country":165,"countryCode":166,"cosmosGeoPoint":1377,"geoPoint":1379,"contacts":33},"Macomb Hematology Oncology PC",{"type":168,"coordinates":1378},[1350,1351],{"lat":1351,"lon":1350},{"facility":1381,"status":175,"city":1382,"state":1043,"zip":1383,"country":165,"countryCode":166,"cosmosGeoPoint":1384,"geoPoint":1388,"contacts":33},"Saint Mary's Oncology\u002FHematology Associates of West Branch","West Branch","48661",{"type":168,"coordinates":1385},[1386,1387],-84.23861,44.27641,{"lat":1387,"lon":1386},{"facility":1390,"status":276,"city":1391,"state":1043,"zip":1044,"country":165,"countryCode":166,"cosmosGeoPoint":1392,"geoPoint":1396,"contacts":1397},"Huron Gastroenterology PC","Ypsilanti",{"type":168,"coordinates":1393},[1394,1395],-83.61299,42.24115,{"lat":1395,"lon":1394},[1398,1399],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1401,"status":276,"city":1391,"state":1043,"zip":1402,"country":165,"countryCode":166,"cosmosGeoPoint":1403,"geoPoint":1405,"contacts":1406},"Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus","48197",{"type":168,"coordinates":1404},[1394,1395],{"lat":1395,"lon":1394},[1407,1408],{"name":286,"role":287,"phone":1052,"phoneExt":33,"email":1053},{"name":530,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1410,"status":1411,"city":1412,"state":1413,"zip":1414,"country":165,"countryCode":166,"cosmosGeoPoint":1415,"geoPoint":1419,"contacts":33},"Mayo Clinic in Rochester","COMPLETED","Rochester","Minnesota","55905",{"type":168,"coordinates":1416},[1417,1418],-92.4699,44.02163,{"lat":1418,"lon":1417},{"facility":1421,"status":175,"city":1422,"state":1423,"zip":1424,"country":165,"countryCode":166,"cosmosGeoPoint":1425,"geoPoint":1429,"contacts":33},"Mercy Oncology and Hematology - Clayton-Clarkson","Ballwin","Missouri","63011",{"type":168,"coordinates":1426},[1427,1428],-90.54623,38.59505,{"lat":1428,"lon":1427},{"facility":1431,"status":175,"city":1432,"state":1423,"zip":1433,"country":165,"countryCode":166,"cosmosGeoPoint":1434,"geoPoint":1438,"contacts":33},"Central Care Cancer Center - Bolivar","Bolivar","65613",{"type":168,"coordinates":1435},[1436,1437],-93.41047,37.61448,{"lat":1437,"lon":1436},{"facility":1440,"status":175,"city":1441,"state":1423,"zip":1442,"country":165,"countryCode":166,"cosmosGeoPoint":1443,"geoPoint":1447,"contacts":33},"Cox Cancer Center Branson","Branson","65616",{"type":168,"coordinates":1444},[1445,1446],-93.21851,36.64367,{"lat":1446,"lon":1445},{"facility":1449,"status":175,"city":1450,"state":1423,"zip":1451,"country":165,"countryCode":166,"cosmosGeoPoint":1452,"geoPoint":1456,"contacts":33},"Mercy Cancer Center - Cape Girardeau","Cape Girardeau","63703",{"type":168,"coordinates":1453},[1454,1455],-89.51815,37.30588,{"lat":1455,"lon":1454},{"facility":1458,"status":175,"city":1450,"state":1423,"zip":1451,"country":165,"countryCode":166,"cosmosGeoPoint":1459,"geoPoint":1461,"contacts":33},"Saint Francis Medical Center",{"type":168,"coordinates":1460},[1454,1455],{"lat":1455,"lon":1454},{"facility":1463,"status":276,"city":1464,"state":1423,"zip":1465,"country":165,"countryCode":166,"cosmosGeoPoint":1466,"geoPoint":1470,"contacts":1471},"Siteman Cancer Center at Saint Peters Hospital","City of Saint Peters","63376",{"type":168,"coordinates":1467},[1468,1469],-90.62651,38.80033,{"lat":1469,"lon":1468},[1472,1475],{"name":286,"role":287,"phone":1473,"phoneExt":33,"email":1474},"800-600-3606","info@siteman.wustl.edu",{"name":1476,"role":157,"phone":33,"phoneExt":33,"email":33},"Geoffrey L. Uy",{"facility":1478,"status":276,"city":1479,"state":1423,"zip":1480,"country":165,"countryCode":166,"cosmosGeoPoint":1481,"geoPoint":1485,"contacts":1486},"Siteman Cancer Center at West County Hospital","Creve Coeur","63141",{"type":168,"coordinates":1482},[1483,1484],-90.42262,38.66089,{"lat":1484,"lon":1483},[1487,1488],{"name":286,"role":287,"phone":1473,"phoneExt":33,"email":1474},{"name":1476,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1490,"status":175,"city":1491,"state":1423,"zip":1492,"country":165,"countryCode":166,"cosmosGeoPoint":1493,"geoPoint":1497,"contacts":33},"Parkland Health Center - Farmington","Farmington","63640",{"type":168,"coordinates":1494},[1495,1496],-90.42179,37.78088,{"lat":1496,"lon":1495},{"facility":1499,"status":175,"city":1500,"state":1423,"zip":1501,"country":165,"countryCode":166,"cosmosGeoPoint":1502,"geoPoint":1506,"contacts":33},"MU Health Care Goldschmidt Cancer Center","Jefferson City","65109",{"type":168,"coordinates":1503},[1504,1505],-92.17352,38.5767,{"lat":1505,"lon":1504},{"facility":1508,"status":175,"city":1509,"state":1423,"zip":1510,"country":165,"countryCode":166,"cosmosGeoPoint":1511,"geoPoint":1515,"contacts":33},"Freeman Health System","Joplin","64804",{"type":168,"coordinates":1512},[1513,1514],-94.51328,37.08423,{"lat":1514,"lon":1513},{"facility":1517,"status":175,"city":1509,"state":1423,"zip":1510,"country":165,"countryCode":166,"cosmosGeoPoint":1518,"geoPoint":1520,"contacts":33},"Mercy Hospital Joplin",{"type":168,"coordinates":1519},[1513,1514],{"lat":1514,"lon":1513},{"facility":1522,"status":175,"city":1523,"state":1423,"zip":1524,"country":165,"countryCode":166,"cosmosGeoPoint":1525,"geoPoint":1529,"contacts":33},"Mercy Clinic-Rolla-Cancer and Hematology","Rolla","65401",{"type":168,"coordinates":1526},[1527,1528],-91.77127,37.95143,{"lat":1528,"lon":1527},{"facility":1531,"status":175,"city":1523,"state":1423,"zip":1524,"country":165,"countryCode":166,"cosmosGeoPoint":1532,"geoPoint":1534,"contacts":33},"Phelps Health Delbert Day Cancer Institute",{"type":168,"coordinates":1533},[1527,1528],{"lat":1528,"lon":1527},{"facility":1536,"status":175,"city":1537,"state":1423,"zip":1538,"country":165,"countryCode":166,"cosmosGeoPoint":1539,"geoPoint":1543,"contacts":33},"Heartland Regional Medical Center","Saint Joseph","64506",{"type":168,"coordinates":1540},[1541,1542],-94.84663,39.76861,{"lat":1542,"lon":1541},{"facility":1545,"status":175,"city":1546,"state":1423,"zip":1547,"country":165,"countryCode":166,"cosmosGeoPoint":1548,"geoPoint":1552,"contacts":33},"Sainte Genevieve County Memorial Hospital","Sainte Genevieve","63670",{"type":168,"coordinates":1549},[1550,1551],-90.04178,37.98144,{"lat":1551,"lon":1550},{"facility":1554,"status":175,"city":938,"state":1423,"zip":1555,"country":165,"countryCode":166,"cosmosGeoPoint":1556,"geoPoint":1560,"contacts":33},"Mercy Hospital Springfield","65804",{"type":168,"coordinates":1557},[1558,1559],-93.29824,37.21533,{"lat":1559,"lon":1558},{"facility":1562,"status":175,"city":938,"state":1423,"zip":1563,"country":165,"countryCode":166,"cosmosGeoPoint":1564,"geoPoint":1566,"contacts":33},"CoxHealth South Hospital","65807",{"type":168,"coordinates":1565},[1558,1559],{"lat":1559,"lon":1558},{"facility":1568,"status":175,"city":1569,"state":1423,"zip":1570,"country":165,"countryCode":166,"cosmosGeoPoint":1571,"geoPoint":1575,"contacts":33},"Mercy Infusion Center - Chippewa","St Louis","63109",{"type":168,"coordinates":1572},[1573,1574],-90.19789,38.62727,{"lat":1574,"lon":1573},{"facility":1577,"status":276,"city":1569,"state":1423,"zip":1578,"country":165,"countryCode":166,"cosmosGeoPoint":1579,"geoPoint":1581,"contacts":1582},"Washington University School of Medicine","63110",{"type":168,"coordinates":1580},[1573,1574],{"lat":1574,"lon":1573},[1583,1584],{"name":286,"role":287,"phone":1473,"phoneExt":33,"email":1474},{"name":1476,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1586,"status":276,"city":1569,"state":1423,"zip":1587,"country":165,"countryCode":166,"cosmosGeoPoint":1588,"geoPoint":1590,"contacts":1591},"Mercy Hospital South","63128",{"type":168,"coordinates":1589},[1573,1574],{"lat":1574,"lon":1573},[1592,1595],{"name":286,"role":287,"phone":1593,"phoneExt":33,"email":1594},"314-525-6042","Danielle.Werle@mercy.net",{"name":1596,"role":157,"phone":33,"phoneExt":33,"email":33},"Jay W. Carlson",{"facility":1598,"status":276,"city":1569,"state":1423,"zip":1599,"country":165,"countryCode":166,"cosmosGeoPoint":1600,"geoPoint":1602,"contacts":1603},"Siteman Cancer Center-South County","63129",{"type":168,"coordinates":1601},[1573,1574],{"lat":1574,"lon":1573},[1604,1605],{"name":286,"role":287,"phone":1473,"phoneExt":33,"email":1474},{"name":1476,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1607,"status":175,"city":1569,"state":1423,"zip":1608,"country":165,"countryCode":166,"cosmosGeoPoint":1609,"geoPoint":1611,"contacts":33},"Missouri Baptist Medical Center","63131",{"type":168,"coordinates":1610},[1573,1574],{"lat":1574,"lon":1573},{"facility":1613,"status":276,"city":1569,"state":1423,"zip":1614,"country":165,"countryCode":166,"cosmosGeoPoint":1615,"geoPoint":1617,"contacts":1618},"Siteman Cancer Center at Christian Hospital","63136",{"type":168,"coordinates":1616},[1573,1574],{"lat":1574,"lon":1573},[1619,1620],{"name":286,"role":287,"phone":1473,"phoneExt":33,"email":1474},{"name":1476,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1622,"status":276,"city":1569,"state":1423,"zip":1480,"country":165,"countryCode":166,"cosmosGeoPoint":1623,"geoPoint":1625,"contacts":1626},"Mercy Hospital Saint Louis",{"type":168,"coordinates":1624},[1573,1574],{"lat":1574,"lon":1573},[1627,1629],{"name":286,"role":287,"phone":1628,"phoneExt":33,"email":33},"314-251-7066",{"name":1596,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1631,"status":175,"city":1632,"state":1423,"zip":1633,"country":165,"countryCode":166,"cosmosGeoPoint":1634,"geoPoint":1638,"contacts":33},"Missouri Baptist Sullivan Hospital","Sullivan","63080",{"type":168,"coordinates":1635},[1636,1637],-91.16042,38.2081,{"lat":1637,"lon":1636},{"facility":1640,"status":175,"city":958,"state":1423,"zip":1641,"country":165,"countryCode":166,"cosmosGeoPoint":1642,"geoPoint":1646,"contacts":33},"Mercy Hospital Washington","63090",{"type":168,"coordinates":1643},[1644,1645],-91.01209,38.55811,{"lat":1645,"lon":1644},{"facility":1648,"status":175,"city":1649,"state":1650,"zip":1651,"country":165,"countryCode":166,"cosmosGeoPoint":1652,"geoPoint":1656,"contacts":33},"Saint Patrick Hospital - Community Hospital","Missoula","Montana","59802",{"type":168,"coordinates":1653},[1654,1655],-113.994,46.87215,{"lat":1655,"lon":1654},{"facility":1658,"status":161,"city":1659,"state":1660,"zip":1661,"country":165,"countryCode":166,"cosmosGeoPoint":1662,"geoPoint":1666,"contacts":33},"Nebraska Medicine-Village Pointe","Omaha","Nebraska","68118",{"type":168,"coordinates":1663},[1664,1665],-95.94043,41.25626,{"lat":1665,"lon":1664},{"facility":1668,"status":161,"city":1659,"state":1660,"zip":1669,"country":165,"countryCode":166,"cosmosGeoPoint":1670,"geoPoint":1672,"contacts":33},"University of Nebraska Medical Center","68198",{"type":168,"coordinates":1671},[1664,1665],{"lat":1665,"lon":1664},{"facility":1674,"status":175,"city":1675,"state":1676,"zip":1677,"country":165,"countryCode":166,"cosmosGeoPoint":1678,"geoPoint":1682,"contacts":33},"Carson Tahoe Regional Medical Center","Carson City","Nevada","89703",{"type":168,"coordinates":1679},[1680,1681],-119.7674,39.1638,{"lat":1681,"lon":1680},{"facility":1684,"status":175,"city":1685,"state":1676,"zip":1686,"country":165,"countryCode":166,"cosmosGeoPoint":1687,"geoPoint":1691,"contacts":33},"Cancer and Blood Specialists-Henderson","Henderson","89052",{"type":168,"coordinates":1688},[1689,1690],-114.98194,36.0397,{"lat":1690,"lon":1689},{"facility":1693,"status":175,"city":1685,"state":1676,"zip":1686,"country":165,"countryCode":166,"cosmosGeoPoint":1694,"geoPoint":1696,"contacts":33},"Comprehensive Cancer Centers of Nevada - Henderson",{"type":168,"coordinates":1695},[1689,1690],{"lat":1690,"lon":1689},{"facility":1698,"status":175,"city":1685,"state":1676,"zip":1686,"country":165,"countryCode":166,"cosmosGeoPoint":1699,"geoPoint":1701,"contacts":33},"Comprehensive Cancer Centers of Nevada-Horizon Ridge",{"type":168,"coordinates":1700},[1689,1690],{"lat":1690,"lon":1689},{"facility":1703,"status":175,"city":1685,"state":1676,"zip":1686,"country":165,"countryCode":166,"cosmosGeoPoint":1704,"geoPoint":1706,"contacts":33},"Las Vegas Cancer Center-Henderson",{"type":168,"coordinates":1705},[1689,1690],{"lat":1690,"lon":1689},{"facility":1708,"status":175,"city":1685,"state":1676,"zip":1709,"country":165,"countryCode":166,"cosmosGeoPoint":1710,"geoPoint":1712,"contacts":33},"Comprehensive Cancer Centers of Nevada-Southeast Henderson","89074",{"type":168,"coordinates":1711},[1689,1690],{"lat":1690,"lon":1689},{"facility":1714,"status":175,"city":1685,"state":1676,"zip":1709,"country":165,"countryCode":166,"cosmosGeoPoint":1715,"geoPoint":1717,"contacts":33},"Las Vegas Urology - Green Valley",{"type":168,"coordinates":1716},[1689,1690],{"lat":1690,"lon":1689},{"facility":1719,"status":175,"city":1685,"state":1676,"zip":1709,"country":165,"countryCode":166,"cosmosGeoPoint":1720,"geoPoint":1722,"contacts":33},"Las Vegas Urology - Pebble",{"type":168,"coordinates":1721},[1689,1690],{"lat":1690,"lon":1689},{"facility":1724,"status":175,"city":1685,"state":1676,"zip":1709,"country":165,"countryCode":166,"cosmosGeoPoint":1725,"geoPoint":1727,"contacts":33},"Oncology Las Vegas - Henderson",{"type":168,"coordinates":1726},[1689,1690],{"lat":1690,"lon":1689},{"facility":1729,"status":175,"city":1685,"state":1676,"zip":1709,"country":165,"countryCode":166,"cosmosGeoPoint":1730,"geoPoint":1732,"contacts":33},"Urology Specialists of Nevada - Green Valley",{"type":168,"coordinates":1731},[1689,1690],{"lat":1690,"lon":1689},{"facility":1734,"status":175,"city":1735,"state":1676,"zip":1709,"country":165,"countryCode":166,"cosmosGeoPoint":1736,"geoPoint":1740,"contacts":33},"Las Vegas Urology - Pecos","Las Vegas",{"type":168,"coordinates":1737},[1738,1739],-115.13722,36.17497,{"lat":1739,"lon":1738},{"facility":1742,"status":175,"city":1735,"state":1676,"zip":1743,"country":165,"countryCode":166,"cosmosGeoPoint":1744,"geoPoint":1746,"contacts":33},"Desert West Surgery","89102",{"type":168,"coordinates":1745},[1738,1739],{"lat":1739,"lon":1738},{"facility":1748,"status":276,"city":1735,"state":1676,"zip":1743,"country":165,"countryCode":166,"cosmosGeoPoint":1749,"geoPoint":1751,"contacts":1752},"OptumCare Cancer Care at Charleston",{"type":168,"coordinates":1750},[1738,1739],{"lat":1739,"lon":1738},[1753,1756],{"name":286,"role":287,"phone":1754,"phoneExt":33,"email":1755},"702-384-0013","research@sncrf.org",{"name":1757,"role":157,"phone":33,"phoneExt":33,"email":33},"John A. Ellerton",{"facility":1759,"status":175,"city":1735,"state":1676,"zip":1743,"country":165,"countryCode":166,"cosmosGeoPoint":1760,"geoPoint":1762,"contacts":33},"University Medical Center of Southern Nevada",{"type":168,"coordinates":1761},[1738,1739],{"lat":1739,"lon":1738},{"facility":1764,"status":175,"city":1735,"state":1676,"zip":1765,"country":165,"countryCode":166,"cosmosGeoPoint":1766,"geoPoint":1768,"contacts":33},"Hope Cancer Care of Nevada","89103",{"type":168,"coordinates":1767},[1738,1739],{"lat":1739,"lon":1738},{"facility":1770,"status":175,"city":1735,"state":1676,"zip":1771,"country":165,"countryCode":166,"cosmosGeoPoint":1772,"geoPoint":1774,"contacts":33},"Radiation Oncology Centers of Nevada Central","89106",{"type":168,"coordinates":1773},[1738,1739],{"lat":1739,"lon":1738},{"facility":1776,"status":175,"city":1735,"state":1676,"zip":1771,"country":165,"countryCode":166,"cosmosGeoPoint":1777,"geoPoint":1779,"contacts":33},"Urology Specialists of Nevada - Central",{"type":168,"coordinates":1778},[1738,1739],{"lat":1739,"lon":1738},{"facility":1781,"status":175,"city":1735,"state":1676,"zip":1782,"country":165,"countryCode":166,"cosmosGeoPoint":1783,"geoPoint":1785,"contacts":33},"HealthCare Partners Medical Group Oncology\u002FHematology-Maryland Parkway","89109",{"type":168,"coordinates":1784},[1738,1739],{"lat":1739,"lon":1738},{"facility":1787,"status":175,"city":1735,"state":1676,"zip":1782,"country":165,"countryCode":166,"cosmosGeoPoint":1788,"geoPoint":1790,"contacts":33},"Sunrise Hospital and Medical Center",{"type":168,"coordinates":1789},[1738,1739],{"lat":1739,"lon":1738},{"facility":1792,"status":175,"city":1735,"state":1676,"zip":1793,"country":165,"countryCode":166,"cosmosGeoPoint":1794,"geoPoint":1796,"contacts":33},"HealthCare Partners Medical Group Oncology\u002FHematology-San Martin","89113",{"type":168,"coordinates":1795},[1738,1739],{"lat":1739,"lon":1738},{"facility":1798,"status":175,"city":1735,"state":1676,"zip":1793,"country":165,"countryCode":166,"cosmosGeoPoint":1799,"geoPoint":1801,"contacts":33},"Las Vegas Prostate Cancer Center",{"type":168,"coordinates":1800},[1738,1739],{"lat":1739,"lon":1738},{"facility":1803,"status":175,"city":1735,"state":1676,"zip":1793,"country":165,"countryCode":166,"cosmosGeoPoint":1804,"geoPoint":1806,"contacts":33},"Las Vegas Urology - Sunset",{"type":168,"coordinates":1805},[1738,1739],{"lat":1739,"lon":1738},{"facility":1808,"status":175,"city":1735,"state":1676,"zip":1793,"country":165,"countryCode":166,"cosmosGeoPoint":1809,"geoPoint":1811,"contacts":33},"Urology Specialists of Nevada - Southwest",{"type":168,"coordinates":1810},[1738,1739],{"lat":1739,"lon":1738},{"facility":1813,"status":175,"city":1735,"state":1676,"zip":1814,"country":165,"countryCode":166,"cosmosGeoPoint":1815,"geoPoint":1817,"contacts":33},"Radiation Oncology Centers of Nevada Southeast","89119",{"type":168,"coordinates":1816},[1738,1739],{"lat":1739,"lon":1738},{"facility":1819,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1821,"geoPoint":1823,"contacts":33},"Ann M Wierman MD LTD","89128",{"type":168,"coordinates":1822},[1738,1739],{"lat":1739,"lon":1738},{"facility":1825,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1826,"geoPoint":1828,"contacts":33},"Comprehensive Cancer Centers of Nevada - Northwest",{"type":168,"coordinates":1827},[1738,1739],{"lat":1739,"lon":1738},{"facility":1830,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1831,"geoPoint":1833,"contacts":33},"HealthCare Partners Medical Group Oncology\u002FHematology-Tenaya",{"type":168,"coordinates":1832},[1738,1739],{"lat":1739,"lon":1738},{"facility":1835,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1836,"geoPoint":1838,"contacts":33},"Las Vegas Urology - Cathedral Rock",{"type":168,"coordinates":1837},[1738,1739],{"lat":1739,"lon":1738},{"facility":1840,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1841,"geoPoint":1843,"contacts":33},"Las Vegas Urology - Smoke Ranch",{"type":168,"coordinates":1842},[1738,1739],{"lat":1739,"lon":1738},{"facility":1845,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1846,"geoPoint":1848,"contacts":33},"Oncology Las Vegas - Tenaya",{"type":168,"coordinates":1847},[1738,1739],{"lat":1739,"lon":1738},{"facility":1850,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1851,"geoPoint":1853,"contacts":33},"OptumCare Cancer Care at MountainView",{"type":168,"coordinates":1852},[1738,1739],{"lat":1739,"lon":1738},{"facility":1855,"status":175,"city":1735,"state":1676,"zip":1820,"country":165,"countryCode":166,"cosmosGeoPoint":1856,"geoPoint":1858,"contacts":33},"Urology Specialists of Nevada - Northwest",{"type":168,"coordinates":1857},[1738,1739],{"lat":1739,"lon":1738},{"facility":1860,"status":175,"city":1735,"state":1676,"zip":1861,"country":165,"countryCode":166,"cosmosGeoPoint":1862,"geoPoint":1864,"contacts":33},"Alliance for Childhood Diseases\u002FCure 4 the Kids Foundation","89135",{"type":168,"coordinates":1863},[1738,1739],{"lat":1739,"lon":1738},{"facility":1866,"status":175,"city":1735,"state":1676,"zip":1867,"country":165,"countryCode":166,"cosmosGeoPoint":1868,"geoPoint":1870,"contacts":33},"Comprehensive Cancer Centers of Nevada - Town Center","89144",{"type":168,"coordinates":1869},[1738,1739],{"lat":1739,"lon":1738},{"facility":1872,"status":175,"city":1735,"state":1676,"zip":1867,"country":165,"countryCode":166,"cosmosGeoPoint":1873,"geoPoint":1875,"contacts":33},"Comprehensive Cancer Centers of Nevada-Summerlin",{"type":168,"coordinates":1874},[1738,1739],{"lat":1739,"lon":1738},{"facility":1877,"status":175,"city":1735,"state":1676,"zip":1867,"country":165,"countryCode":166,"cosmosGeoPoint":1878,"geoPoint":1880,"contacts":33},"Summerlin Hospital Medical Center",{"type":168,"coordinates":1879},[1738,1739],{"lat":1739,"lon":1738},{"facility":1882,"status":175,"city":1735,"state":1676,"zip":1883,"country":165,"countryCode":166,"cosmosGeoPoint":1884,"geoPoint":1886,"contacts":33},"Las Vegas Cancer Center-Medical Center","89148-2405",{"type":168,"coordinates":1885},[1738,1739],{"lat":1739,"lon":1738},{"facility":1888,"status":175,"city":1735,"state":1676,"zip":1889,"country":165,"countryCode":166,"cosmosGeoPoint":1890,"geoPoint":1892,"contacts":33},"Comprehensive Cancer Centers of Nevada","89148",{"type":168,"coordinates":1891},[1738,1739],{"lat":1739,"lon":1738},{"facility":1894,"status":175,"city":1735,"state":1676,"zip":1895,"country":165,"countryCode":166,"cosmosGeoPoint":1896,"geoPoint":1898,"contacts":33},"HealthCare Partners Medical Group Oncology\u002FHematology-Centennial Hills","89149",{"type":168,"coordinates":1897},[1738,1739],{"lat":1739,"lon":1738},{"facility":1900,"status":175,"city":1735,"state":1676,"zip":1901,"country":165,"countryCode":166,"cosmosGeoPoint":1902,"geoPoint":1904,"contacts":33},"Comprehensive Cancer Centers of Nevada - Central Valley","89169",{"type":168,"coordinates":1903},[1738,1739],{"lat":1739,"lon":1738},{"facility":1906,"status":175,"city":1735,"state":1676,"zip":1901,"country":165,"countryCode":166,"cosmosGeoPoint":1907,"geoPoint":1909,"contacts":33},"University Cancer Center",{"type":168,"coordinates":1908},[1738,1739],{"lat":1739,"lon":1738},{"facility":1911,"status":276,"city":1735,"state":1676,"zip":1912,"country":165,"countryCode":166,"cosmosGeoPoint":1913,"geoPoint":1915,"contacts":1916},"OptumCare Cancer Care at Fort Apache","89183",{"type":168,"coordinates":1914},[1738,1739],{"lat":1739,"lon":1738},[1917,1918],{"name":286,"role":287,"phone":1754,"phoneExt":33,"email":1755},{"name":1757,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1920,"status":175,"city":1921,"state":1676,"zip":1922,"country":165,"countryCode":166,"cosmosGeoPoint":1923,"geoPoint":1927,"contacts":33},"Hope Cancer Care of Nevada-Pahrump","Pahrump","89048",{"type":168,"coordinates":1924},[1925,1926],-115.98391,36.20829,{"lat":1926,"lon":1925},{"facility":1929,"status":175,"city":1930,"state":1676,"zip":1931,"country":165,"countryCode":166,"cosmosGeoPoint":1932,"geoPoint":1936,"contacts":33},"Renown Regional Medical Center","Reno","89502",{"type":168,"coordinates":1933},[1934,1935],-119.8138,39.52963,{"lat":1935,"lon":1934},{"facility":1938,"status":175,"city":1930,"state":1676,"zip":1939,"country":165,"countryCode":166,"cosmosGeoPoint":1940,"geoPoint":1942,"contacts":33},"Saint Mary's Regional Medical Center","89503",{"type":168,"coordinates":1941},[1934,1935],{"lat":1935,"lon":1934},{"facility":1944,"status":175,"city":1930,"state":1676,"zip":1945,"country":165,"countryCode":166,"cosmosGeoPoint":1946,"geoPoint":1948,"contacts":33},"Radiation Oncology Associates","89509",{"type":168,"coordinates":1947},[1934,1935],{"lat":1935,"lon":1934},{"facility":1950,"status":161,"city":1951,"state":1952,"zip":1953,"country":165,"countryCode":166,"cosmosGeoPoint":1954,"geoPoint":1958,"contacts":33},"Roswell Park Cancer Institute","Buffalo","New York","14263",{"type":168,"coordinates":1955},[1956,1957],-78.87837,42.88645,{"lat":1957,"lon":1956},{"facility":1960,"status":276,"city":1961,"state":1952,"zip":1962,"country":165,"countryCode":166,"cosmosGeoPoint":1963,"geoPoint":1967,"contacts":1968},"Northwell Health\u002FCenter for Advanced Medicine","Lake Success","11042",{"type":168,"coordinates":1964},[1965,1966],-73.71763,40.77066,{"lat":1966,"lon":1965},[1969,1971],{"name":286,"role":287,"phone":1970,"phoneExt":33,"email":33},"516-734-8896",{"name":1972,"role":157,"phone":33,"phoneExt":33,"email":33},"Bradley H. Goldberg",{"facility":1974,"status":276,"city":1975,"state":1952,"zip":1976,"country":165,"countryCode":166,"cosmosGeoPoint":1977,"geoPoint":1981,"contacts":1982},"North Shore University Hospital","Manhasset","11030",{"type":168,"coordinates":1978},[1979,1980],-73.69957,40.79788,{"lat":1980,"lon":1979},[1983,1984],{"name":286,"role":287,"phone":1970,"phoneExt":33,"email":33},{"name":1972,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1986,"status":276,"city":1987,"state":1952,"zip":1988,"country":165,"countryCode":166,"cosmosGeoPoint":1989,"geoPoint":1993,"contacts":1994},"Long Island Jewish Medical Center","New Hyde Park","11040",{"type":168,"coordinates":1990},[1991,1992],-73.68791,40.7351,{"lat":1992,"lon":1991},[1995,1996],{"name":286,"role":287,"phone":1970,"phoneExt":33,"email":33},{"name":1972,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":1998,"status":161,"city":1952,"state":1952,"zip":1999,"country":165,"countryCode":166,"cosmosGeoPoint":2000,"geoPoint":2004,"contacts":33},"NYP\u002FWeill Cornell Medical Center","10065",{"type":168,"coordinates":2001},[2002,2003],-74.00597,40.71427,{"lat":2003,"lon":2002},{"facility":2006,"status":276,"city":1412,"state":1952,"zip":2007,"country":165,"countryCode":166,"cosmosGeoPoint":2008,"geoPoint":2012,"contacts":2013},"University of Rochester","14642",{"type":168,"coordinates":2009},[2010,2011],-77.61556,43.15478,{"lat":2011,"lon":2010},[2014,2016],{"name":286,"role":287,"phone":2015,"phoneExt":33,"email":33},"585-275-5830",{"name":2017,"role":157,"phone":33,"phoneExt":33,"email":33},"Kristen M. O'Dwyer",{"facility":2019,"status":276,"city":2020,"state":1952,"zip":2021,"country":165,"countryCode":166,"cosmosGeoPoint":2022,"geoPoint":2026,"contacts":2027},"Stony Brook University Medical Center","Stony Brook","11794",{"type":168,"coordinates":2023},[2024,2025],-73.14094,40.92565,{"lat":2025,"lon":2024},[2028,2030],{"name":286,"role":287,"phone":2029,"phoneExt":33,"email":33},"800-862-2215",{"name":2031,"role":157,"phone":33,"phoneExt":33,"email":33},"Suhu Liu",{"facility":2033,"status":175,"city":2034,"state":2035,"zip":2036,"country":165,"countryCode":166,"cosmosGeoPoint":2037,"geoPoint":2041,"contacts":33},"UNC Lineberger Comprehensive Cancer Center","Chapel Hill","North Carolina","27599",{"type":168,"coordinates":2038},[2039,2040],-79.05584,35.9132,{"lat":2040,"lon":2039},{"facility":2043,"status":161,"city":2044,"state":2035,"zip":2045,"country":165,"countryCode":166,"cosmosGeoPoint":2046,"geoPoint":2050,"contacts":33},"Duke University Medical Center","Durham","27710",{"type":168,"coordinates":2047},[2048,2049],-78.89862,35.99403,{"lat":2049,"lon":2048},{"facility":2052,"status":175,"city":2053,"state":2035,"zip":2054,"country":165,"countryCode":166,"cosmosGeoPoint":2055,"geoPoint":2059,"contacts":33},"East Carolina University","Greenville","27834",{"type":168,"coordinates":2056},[2057,2058],-77.36635,35.61266,{"lat":2058,"lon":2057},{"facility":2061,"status":276,"city":2062,"state":2035,"zip":2063,"country":165,"countryCode":166,"cosmosGeoPoint":2064,"geoPoint":2068,"contacts":2069},"Wake Forest University Health Sciences","Winston-Salem","27157",{"type":168,"coordinates":2065},[2066,2067],-80.24422,36.09986,{"lat":2067,"lon":2066},[2070,2072],{"name":286,"role":287,"phone":2071,"phoneExt":33,"email":33},"336-713-6771",{"name":2073,"role":157,"phone":33,"phoneExt":33,"email":33},"Bayard L. Powell",{"facility":2075,"status":276,"city":2076,"state":2077,"zip":2078,"country":165,"countryCode":166,"cosmosGeoPoint":2079,"geoPoint":2083,"contacts":2084},"University of Cincinnati Cancer Center-UC Medical Center","Cincinnati","Ohio","45219",{"type":168,"coordinates":2080},[2081,2082],-84.51439,39.12711,{"lat":2082,"lon":2081},[2085,2088],{"name":286,"role":287,"phone":2086,"phoneExt":33,"email":2087},"513-584-7698","cancer@uchealth.com",{"name":2089,"role":157,"phone":33,"phoneExt":33,"email":33},"Emily K. Curran",{"facility":2091,"status":276,"city":2092,"state":2077,"zip":2093,"country":165,"countryCode":166,"cosmosGeoPoint":2094,"geoPoint":2098,"contacts":2099},"Ohio State University Comprehensive Cancer Center","Columbus","43210",{"type":168,"coordinates":2095},[2096,2097],-82.99879,39.96118,{"lat":2097,"lon":2096},[2100,2103],{"name":286,"role":287,"phone":2101,"phoneExt":33,"email":2102},"800-293-5066","Jamesline@osumc.edu",{"name":2104,"role":157,"phone":33,"phoneExt":33,"email":33},"Gregory K. Behbehani",{"facility":2106,"status":276,"city":2107,"state":2077,"zip":2108,"country":165,"countryCode":166,"cosmosGeoPoint":2109,"geoPoint":2113,"contacts":2114},"University of Cincinnati Cancer Center-West Chester","West Chester","45069",{"type":168,"coordinates":2110},[2111,2112],-84.40716,39.33172,{"lat":2112,"lon":2111},[2115,2116],{"name":286,"role":287,"phone":2086,"phoneExt":33,"email":2087},{"name":2089,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2118,"status":276,"city":2119,"state":2120,"zip":2121,"country":165,"countryCode":166,"cosmosGeoPoint":2122,"geoPoint":2126,"contacts":2127},"University of Oklahoma Health Sciences Center","Oklahoma City","Oklahoma","73104",{"type":168,"coordinates":2123},[2124,2125],-97.51643,35.46756,{"lat":2125,"lon":2124},[2128,2131],{"name":286,"role":287,"phone":2129,"phoneExt":33,"email":2130},"405-271-8777","ou-clinical-trials@ouhsc.edu",{"name":2132,"role":157,"phone":33,"phoneExt":33,"email":33},"Zimu Gong",{"facility":2134,"status":175,"city":2119,"state":2120,"zip":2135,"country":165,"countryCode":166,"cosmosGeoPoint":2136,"geoPoint":2138,"contacts":33},"Mercy Hospital Oklahoma City","73120",{"type":168,"coordinates":2137},[2124,2125],{"lat":2125,"lon":2124},{"facility":2140,"status":175,"city":2141,"state":2142,"zip":2143,"country":165,"countryCode":166,"cosmosGeoPoint":2144,"geoPoint":2148,"contacts":33},"Saint Charles Health System","Bend","Oregon","97701",{"type":168,"coordinates":2145},[2146,2147],-121.31531,44.05817,{"lat":2147,"lon":2146},{"facility":2150,"status":175,"city":2151,"state":2142,"zip":2152,"country":165,"countryCode":166,"cosmosGeoPoint":2153,"geoPoint":2157,"contacts":33},"Clackamas Radiation Oncology Center","Clackamas","97015",{"type":168,"coordinates":2154},[2155,2156],-122.57037,45.40762,{"lat":2156,"lon":2155},{"facility":2159,"status":175,"city":2151,"state":2142,"zip":2152,"country":165,"countryCode":166,"cosmosGeoPoint":2160,"geoPoint":2162,"contacts":33},"Providence Cancer Institute Clackamas Clinic",{"type":168,"coordinates":2161},[2155,2156],{"lat":2156,"lon":2155},{"facility":2164,"status":175,"city":2165,"state":2142,"zip":2166,"country":165,"countryCode":166,"cosmosGeoPoint":2167,"geoPoint":2171,"contacts":33},"Bay Area Hospital","Coos Bay","97420",{"type":168,"coordinates":2168},[2169,2170],-124.21789,43.3665,{"lat":2170,"lon":2169},{"facility":2173,"status":175,"city":2174,"state":2142,"zip":2175,"country":165,"countryCode":166,"cosmosGeoPoint":2176,"geoPoint":2180,"contacts":33},"Providence Newberg Medical Center","Newberg","97132",{"type":168,"coordinates":2177},[2178,2179],-122.97316,45.30012,{"lat":2179,"lon":2178},{"facility":2182,"status":175,"city":2183,"state":2142,"zip":2184,"country":165,"countryCode":166,"cosmosGeoPoint":2185,"geoPoint":2189,"contacts":33},"Providence Willamette Falls Medical Center","Oregon City","97045",{"type":168,"coordinates":2186},[2187,2188],-122.60676,45.35734,{"lat":2188,"lon":2187},{"facility":2191,"status":276,"city":2192,"state":2142,"zip":2193,"country":165,"countryCode":166,"cosmosGeoPoint":2194,"geoPoint":2198,"contacts":2199},"Providence Portland Medical Center","Portland","97213",{"type":168,"coordinates":2195},[2196,2197],-122.67621,45.52345,{"lat":2197,"lon":2196},[2200,2203],{"name":286,"role":287,"phone":2201,"phoneExt":33,"email":2202},"503-215-2614","CanRsrchStudies@providence.org",{"name":2204,"role":157,"phone":33,"phoneExt":33,"email":33},"Alison K. Conlin",{"facility":2206,"status":276,"city":2192,"state":2142,"zip":2207,"country":165,"countryCode":166,"cosmosGeoPoint":2208,"geoPoint":2210,"contacts":2211},"Providence Saint Vincent Medical Center","97225",{"type":168,"coordinates":2209},[2196,2197],{"lat":2197,"lon":2196},[2212,2213],{"name":286,"role":287,"phone":2201,"phoneExt":33,"email":2202},{"name":2204,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2215,"status":161,"city":2192,"state":2142,"zip":2216,"country":165,"countryCode":166,"cosmosGeoPoint":2217,"geoPoint":2219,"contacts":33},"Oregon Health and Science University","97239",{"type":168,"coordinates":2218},[2196,2197],{"lat":2197,"lon":2196},{"facility":2221,"status":175,"city":2222,"state":2142,"zip":2223,"country":165,"countryCode":166,"cosmosGeoPoint":2224,"geoPoint":2228,"contacts":33},"Saint Charles Health System-Redmond","Redmond","97756",{"type":168,"coordinates":2225},[2226,2227],-121.17392,44.27262,{"lat":2227,"lon":2226},{"facility":2230,"status":175,"city":2231,"state":2232,"zip":2233,"country":165,"countryCode":166,"cosmosGeoPoint":2234,"geoPoint":2238,"contacts":33},"Lehigh Valley Hospital-Cedar Crest","Allentown","Pennsylvania","18103",{"type":168,"coordinates":2235},[2236,2237],-75.49018,40.60843,{"lat":2237,"lon":2236},{"facility":2240,"status":175,"city":2241,"state":2232,"zip":2242,"country":165,"countryCode":166,"cosmosGeoPoint":2243,"geoPoint":2247,"contacts":33},"Lehigh Valley Hospital - Muhlenberg","Bethlehem","18017",{"type":168,"coordinates":2244},[2245,2246],-75.37046,40.62593,{"lat":2246,"lon":2245},{"facility":2249,"status":175,"city":2250,"state":2232,"zip":2251,"country":165,"countryCode":166,"cosmosGeoPoint":2252,"geoPoint":2256,"contacts":33},"Christiana Care Health System-Concord Health Center","Chadds Ford","19317",{"type":168,"coordinates":2253},[2254,2255],-75.59132,39.87178,{"lat":2255,"lon":2254},{"facility":2258,"status":175,"city":2259,"state":2232,"zip":2260,"country":165,"countryCode":166,"cosmosGeoPoint":2261,"geoPoint":2265,"contacts":33},"Pocono Medical Center","East Stroudsburg","18301",{"type":168,"coordinates":2262},[2263,2264],-75.18129,40.99954,{"lat":2264,"lon":2263},{"facility":2267,"status":175,"city":2268,"state":2232,"zip":2269,"country":165,"countryCode":166,"cosmosGeoPoint":2270,"geoPoint":2274,"contacts":33},"Lehigh Valley Hospital-Hazleton","Hazleton","18201",{"type":168,"coordinates":2271},[2272,2273],-75.97465,40.95842,{"lat":2273,"lon":2272},{"facility":2276,"status":161,"city":2277,"state":2232,"zip":2278,"country":165,"countryCode":166,"cosmosGeoPoint":2279,"geoPoint":2283,"contacts":33},"Thomas Jefferson University Hospital","Philadelphia","19107",{"type":168,"coordinates":2280},[2281,2282],-75.16362,39.95238,{"lat":2282,"lon":2281},{"facility":2285,"status":276,"city":2286,"state":2287,"zip":2288,"country":165,"countryCode":166,"cosmosGeoPoint":2289,"geoPoint":2293,"contacts":2294},"VCU Massey Comprehensive Cancer Center","Richmond","Virginia","23298",{"type":168,"coordinates":2290},[2291,2292],-77.46026,37.55376,{"lat":2292,"lon":2291},[2295,2298],{"name":286,"role":287,"phone":2296,"phoneExt":33,"email":2297},"804-628-6430","CTOclinops@vcu.edu",{"name":2299,"role":157,"phone":33,"phoneExt":33,"email":33},"Keri R. Maher",{"facility":2301,"status":175,"city":2302,"state":958,"zip":2303,"country":165,"countryCode":166,"cosmosGeoPoint":2304,"geoPoint":2308,"contacts":33},"Providence Regional Cancer System-Aberdeen","Aberdeen","98520",{"type":168,"coordinates":2305},[2306,2307],-123.81572,46.97537,{"lat":2307,"lon":2306},{"facility":2310,"status":175,"city":2311,"state":958,"zip":2312,"country":165,"countryCode":166,"cosmosGeoPoint":2313,"geoPoint":2317,"contacts":33},"Overlake Medical Center","Bellevue","98004",{"type":168,"coordinates":2314},[2315,2316],-122.20068,47.61038,{"lat":2316,"lon":2315},{"facility":2319,"status":175,"city":2320,"state":958,"zip":2321,"country":165,"countryCode":166,"cosmosGeoPoint":2322,"geoPoint":2326,"contacts":33},"PeaceHealth Saint Joseph Medical Center","Bellingham","98225",{"type":168,"coordinates":2323},[2324,2325],-122.48822,48.75955,{"lat":2325,"lon":2324},{"facility":2328,"status":175,"city":611,"state":958,"zip":2329,"country":165,"countryCode":166,"cosmosGeoPoint":2330,"geoPoint":2334,"contacts":33},"Providence Regional Cancer System-Centralia","98531",{"type":168,"coordinates":2331},[2332,2333],-122.9543,46.71621,{"lat":2333,"lon":2332},{"facility":2336,"status":175,"city":2337,"state":958,"zip":2338,"country":165,"countryCode":166,"cosmosGeoPoint":2339,"geoPoint":2343,"contacts":33},"Swedish Cancer Institute-Edmonds","Edmonds","98026",{"type":168,"coordinates":2340},[2341,2342],-122.37736,47.81065,{"lat":2342,"lon":2341},{"facility":2345,"status":175,"city":2346,"state":958,"zip":2347,"country":165,"countryCode":166,"cosmosGeoPoint":2348,"geoPoint":2352,"contacts":33},"Providence Regional Cancer Partnership","Everett","98201",{"type":168,"coordinates":2349},[2350,2351],-122.20208,47.97898,{"lat":2351,"lon":2350},{"facility":2354,"status":175,"city":2355,"state":958,"zip":2356,"country":165,"countryCode":166,"cosmosGeoPoint":2357,"geoPoint":2361,"contacts":33},"Swedish Cancer Institute-Issaquah","Issaquah","98029",{"type":168,"coordinates":2358},[2359,2360],-122.03262,47.5301,{"lat":2360,"lon":2359},{"facility":2363,"status":175,"city":2364,"state":958,"zip":2365,"country":165,"countryCode":166,"cosmosGeoPoint":2366,"geoPoint":2370,"contacts":33},"Kadlec Clinic Hematology and Oncology","Kennewick","99336",{"type":168,"coordinates":2367},[2368,2369],-119.13723,46.21125,{"lat":2369,"lon":2368},{"facility":2372,"status":175,"city":2373,"state":958,"zip":2374,"country":165,"countryCode":166,"cosmosGeoPoint":2375,"geoPoint":2379,"contacts":33},"Providence Regional Cancer System-Lacey","Lacey","98503",{"type":168,"coordinates":2376},[2377,2378],-122.82319,47.03426,{"lat":2378,"lon":2377},{"facility":2381,"status":175,"city":2382,"state":958,"zip":2383,"country":165,"countryCode":166,"cosmosGeoPoint":2384,"geoPoint":2388,"contacts":33},"PeaceHealth Saint John Medical Center","Longview","98632",{"type":168,"coordinates":2385},[2386,2387],-122.93817,46.13817,{"lat":2387,"lon":2386},{"facility":2390,"status":175,"city":2391,"state":958,"zip":2392,"country":165,"countryCode":166,"cosmosGeoPoint":2393,"geoPoint":2397,"contacts":33},"Valley Medical Center","Renton","98055",{"type":168,"coordinates":2394},[2395,2396],-122.21707,47.48288,{"lat":2396,"lon":2395},{"facility":2399,"status":175,"city":2400,"state":958,"zip":2401,"country":165,"countryCode":166,"cosmosGeoPoint":2402,"geoPoint":2406,"contacts":33},"Pacific Gynecology Specialists","Seattle","98104",{"type":168,"coordinates":2403},[2404,2405],-122.33207,47.60621,{"lat":2405,"lon":2404},{"facility":2408,"status":175,"city":2400,"state":958,"zip":2409,"country":165,"countryCode":166,"cosmosGeoPoint":2410,"geoPoint":2412,"contacts":33},"Swedish Medical Center-Ballard Campus","98107",{"type":168,"coordinates":2411},[2404,2405],{"lat":2405,"lon":2404},{"facility":2414,"status":175,"city":2400,"state":958,"zip":2415,"country":165,"countryCode":166,"cosmosGeoPoint":2416,"geoPoint":2418,"contacts":33},"Swedish Medical Center-Cherry Hill","98122-5711",{"type":168,"coordinates":2417},[2404,2405],{"lat":2405,"lon":2404},{"facility":2420,"status":175,"city":2400,"state":958,"zip":2421,"country":165,"countryCode":166,"cosmosGeoPoint":2422,"geoPoint":2424,"contacts":33},"Swedish Medical Center-First Hill","98122",{"type":168,"coordinates":2423},[2404,2405],{"lat":2405,"lon":2404},{"facility":2426,"status":175,"city":2427,"state":958,"zip":2428,"country":165,"countryCode":166,"cosmosGeoPoint":2429,"geoPoint":2433,"contacts":33},"PeaceHealth United General Medical Center","Sedro-Woolley","98284",{"type":168,"coordinates":2430},[2431,2432],-122.23611,48.50389,{"lat":2432,"lon":2431},{"facility":2435,"status":175,"city":2436,"state":958,"zip":2437,"country":165,"countryCode":166,"cosmosGeoPoint":2438,"geoPoint":2442,"contacts":33},"Providence Regional Cancer System-Shelton","Shelton","98584",{"type":168,"coordinates":2439},[2440,2441],-123.10071,47.21509,{"lat":2441,"lon":2440},{"facility":2444,"status":175,"city":2445,"state":958,"zip":2446,"country":165,"countryCode":166,"cosmosGeoPoint":2447,"geoPoint":2451,"contacts":33},"PeaceHealth Southwest Medical Center","Vancouver","98664",{"type":168,"coordinates":2448},[2449,2450],-122.66149,45.63873,{"lat":2450,"lon":2449},{"facility":2453,"status":175,"city":2454,"state":958,"zip":2455,"country":165,"countryCode":166,"cosmosGeoPoint":2456,"geoPoint":2460,"contacts":33},"Providence Saint Mary Regional Cancer Center","Walla Walla","99362",{"type":168,"coordinates":2457},[2458,2459],-118.34302,46.06458,{"lat":2459,"lon":2458},{"facility":2462,"status":175,"city":2463,"state":958,"zip":2464,"country":165,"countryCode":166,"cosmosGeoPoint":2465,"geoPoint":2469,"contacts":33},"North Star Lodge Cancer Center at Yakima Valley Memorial Hospital","Yakima","98902",{"type":168,"coordinates":2466},[2467,2468],-120.5059,46.60207,{"lat":2468,"lon":2467},{"facility":2471,"status":175,"city":2472,"state":958,"zip":2473,"country":165,"countryCode":166,"cosmosGeoPoint":2474,"geoPoint":2478,"contacts":33},"Providence Regional Cancer System-Yelm","Yelm","98597",{"type":168,"coordinates":2475},[2476,2477],-122.60596,46.94204,{"lat":2477,"lon":2476},{"facility":2480,"status":276,"city":2481,"state":2482,"zip":2483,"country":165,"countryCode":166,"cosmosGeoPoint":2484,"geoPoint":2488,"contacts":2489},"West Virginia University Healthcare","Morgantown","West Virginia","26506",{"type":168,"coordinates":2485},[2486,2487],-79.9559,39.62953,{"lat":2487,"lon":2486},[2490,2493],{"name":286,"role":287,"phone":2491,"phoneExt":33,"email":2492},"304-293-7374","cancertrialsinfo@hsc.wvu.edu",{"name":2494,"role":157,"phone":33,"phoneExt":33,"email":33},"Ashkan Emadi",{"facility":2496,"status":276,"city":2497,"state":2498,"zip":2499,"country":165,"countryCode":166,"cosmosGeoPoint":2500,"geoPoint":2504,"contacts":2505},"Marshfield Medical Center-EC Cancer Center","Eau Claire","Wisconsin","54701",{"type":168,"coordinates":2501},[2502,2503],-91.49849,44.81135,{"lat":2503,"lon":2502},[2506,2509],{"name":286,"role":287,"phone":2507,"phoneExt":33,"email":2508},"800-782-8581","oncology.clinical.trials@marshfieldresearch.org",{"name":2510,"role":157,"phone":33,"phoneExt":33,"email":33},"Kareem H. Abdelhadi",{"facility":2512,"status":161,"city":2513,"state":2498,"zip":2514,"country":165,"countryCode":166,"cosmosGeoPoint":2515,"geoPoint":2519,"contacts":33},"University of Wisconsin Carbone Cancer Center - Eastpark Medical Center","Madison","53718",{"type":168,"coordinates":2516},[2517,2518],-89.40123,43.07305,{"lat":2518,"lon":2517},{"facility":2521,"status":161,"city":2513,"state":2498,"zip":2522,"country":165,"countryCode":166,"cosmosGeoPoint":2523,"geoPoint":2525,"contacts":33},"University of Wisconsin Carbone Cancer Center - University Hospital","53792",{"type":168,"coordinates":2524},[2517,2518],{"lat":2518,"lon":2517},{"facility":2527,"status":276,"city":2528,"state":2498,"zip":2529,"country":165,"countryCode":166,"cosmosGeoPoint":2530,"geoPoint":2534,"contacts":2535},"Marshfield Medical Center-Marshfield","Marshfield","54449",{"type":168,"coordinates":2531},[2532,2533],-90.1718,44.66885,{"lat":2533,"lon":2532},[2536,2537],{"name":286,"role":287,"phone":2507,"phoneExt":33,"email":2508},{"name":2510,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2539,"status":276,"city":2540,"state":2498,"zip":2541,"country":165,"countryCode":166,"cosmosGeoPoint":2542,"geoPoint":2546,"contacts":2547},"Froedtert Menomonee Falls Hospital","Menomonee Falls","53051",{"type":168,"coordinates":2543},[2544,2545],-88.11731,43.1789,{"lat":2545,"lon":2544},[2548,2550],{"name":286,"role":287,"phone":2549,"phoneExt":33,"email":33},"262-257-5100",{"name":2551,"role":157,"phone":33,"phoneExt":33,"email":33},"Ehab L. Atallah",{"facility":2553,"status":276,"city":2554,"state":2498,"zip":2555,"country":165,"countryCode":166,"cosmosGeoPoint":2556,"geoPoint":2560,"contacts":2561},"Medical College of Wisconsin","Milwaukee","53226",{"type":168,"coordinates":2557},[2558,2559],-87.90647,43.0389,{"lat":2559,"lon":2558},[2562,2564],{"name":286,"role":287,"phone":2563,"phoneExt":33,"email":33},"414-805-3666",{"name":2551,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2566,"status":276,"city":2567,"state":2498,"zip":2568,"country":165,"countryCode":166,"cosmosGeoPoint":2569,"geoPoint":2573,"contacts":2574},"Marshfield Medical Center - Minocqua","Minocqua","54548",{"type":168,"coordinates":2570},[2571,2572],-89.71098,45.87134,{"lat":2572,"lon":2571},[2575,2576],{"name":286,"role":287,"phone":2507,"phoneExt":33,"email":2508},{"name":2510,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2578,"status":276,"city":2579,"state":2498,"zip":2580,"country":165,"countryCode":166,"cosmosGeoPoint":2581,"geoPoint":2585,"contacts":2586},"Froedtert and MCW Moorland Reserve Health Center","New Berlin","53151",{"type":168,"coordinates":2582},[2583,2584],-88.10842,42.9764,{"lat":2584,"lon":2583},[2587,2589],{"name":286,"role":287,"phone":2588,"phoneExt":33,"email":33},"414-805-0505",{"name":2551,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2591,"status":276,"city":2592,"state":2498,"zip":2593,"country":165,"countryCode":166,"cosmosGeoPoint":2594,"geoPoint":2598,"contacts":2599},"Drexel Town Square Health Center","Oak Creek","53154",{"type":168,"coordinates":2595},[2596,2597],-87.86314,42.88585,{"lat":2597,"lon":2596},[2600,2601],{"name":286,"role":287,"phone":2588,"phoneExt":33,"email":33},{"name":2551,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2603,"status":276,"city":2604,"state":2498,"zip":2605,"country":165,"countryCode":166,"cosmosGeoPoint":2606,"geoPoint":2610,"contacts":2611},"Marshfield Medical Center-Rice Lake","Rice Lake","54868",{"type":168,"coordinates":2607},[2608,2609],-91.73823,45.50607,{"lat":2609,"lon":2608},[2612,2613],{"name":286,"role":287,"phone":2507,"phoneExt":33,"email":2508},{"name":2510,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2615,"status":276,"city":2616,"state":2498,"zip":2617,"country":165,"countryCode":166,"cosmosGeoPoint":2618,"geoPoint":2622,"contacts":2623},"Marshfield Medical Center-River Region at Stevens Point","Stevens Point","54482",{"type":168,"coordinates":2619},[2620,2621],-89.57456,44.52358,{"lat":2621,"lon":2620},[2624,2625],{"name":286,"role":287,"phone":2507,"phoneExt":33,"email":2508},{"name":2510,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2627,"status":276,"city":2628,"state":2498,"zip":2629,"country":165,"countryCode":166,"cosmosGeoPoint":2630,"geoPoint":2634,"contacts":2635},"Froedtert West Bend Hospital\u002FKraemer Cancer Center","West Bend","53095",{"type":168,"coordinates":2631},[2632,2633],-88.18343,43.42528,{"lat":2633,"lon":2632},[2636,2637],{"name":286,"role":287,"phone":2588,"phoneExt":33,"email":33},{"name":2551,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2639,"status":276,"city":2640,"state":2498,"zip":2641,"country":165,"countryCode":166,"cosmosGeoPoint":2642,"geoPoint":2646,"contacts":2647},"Marshfield Medical Center - Weston","Weston","54476",{"type":168,"coordinates":2643},[2644,2645],-89.54762,44.8908,{"lat":2645,"lon":2644},[2648,2649],{"name":286,"role":287,"phone":2507,"phoneExt":33,"email":2508},{"name":2510,"role":157,"phone":33,"phoneExt":33,"email":33},{"facility":2651,"status":276,"city":2652,"state":33,"zip":2653,"country":2654,"countryCode":2655,"cosmosGeoPoint":2656,"geoPoint":2660,"contacts":2661},"Centro Comprensivo de Cancer de UPR","San Juan","00927","Puerto Rico","PR",{"type":168,"coordinates":2657},[2658,2659],-66.10572,18.46633,{"lat":2659,"lon":2658},[2662,2665],{"name":286,"role":287,"phone":2663,"phoneExt":33,"email":2664},"888-823-5923","ctsucontact@westat.com",{"name":2666,"role":157,"phone":33,"phoneExt":33,"email":33},"Luis J. Santos Reyes",{"facility":2668,"status":276,"city":2652,"state":33,"zip":2669,"country":2654,"countryCode":2655,"cosmosGeoPoint":2670,"geoPoint":2672,"contacts":2673},"San Juan City Hospital","00936",{"type":168,"coordinates":2671},[2658,2659],{"lat":2659,"lon":2658},[2674,2676],{"name":286,"role":287,"phone":2675,"phoneExt":33,"email":33},"787-763-1296",{"name":2666,"role":157,"phone":33,"phoneExt":33,"email":33},{"type":2678,"investigatorFullName":33,"investigatorTitle":33,"investigatorAffiliation":33,"oldNameTitle":33,"oldOrganization":33},"SPONSOR","100342529","phase-2-inotuzumab-ozogamicin-and-blinatumomab-with-or-without-ponatinib-in-treating-patients-with-newly-diagnosed-recurrent-or-refractory-cd22-positive-b-lineage-acute-lymphoblastic-leukemia-100342529",false,"NCT03739814","Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia","A Phase II Study of Inotuzumab Ozogamicin Followed by Blinatumomab for Ph-Negative, CD22-Positive B-Lineage Acute Lymphoblastic Leukemia in Newly Diagnosed Older Adults or Adults With Relapsed or Refractory Disease","Inclusion Criteria:\n\n* STEP 0: Submission of bone marrow aspirate and peripheral blood for MRD analysis is mandatory prior to registration; the bone marrow sample should be from the first aspiration (i.e. first pull). Aspirate needle should be redirected if needed to get first pull bone marrow aspirate. It should be initiated as soon as possible after pre-registration. The specimens should be sent to the HEME Biobank.\n\n  * Lumbar Puncture (Spinal Tap) and Intrathecal Methotrexate:\n\n    * Patients may receive the day 1 of course IA dose of intrathecal (IT) methotrexate during the prior-to-registration lumbar puncture (or the venous line placement) to avoid a second lumbar puncture. If the dose is administered prior to registration, then systemic chemotherapy must begin within 7 days of this IT chemotherapy.\n* STEP 1: Morphologic diagnosis of precursor B-cell acute lymphoblastic leukemia (ALL) based on World Health Organization (WHO) criteria. Patients with Burkitt lymphoma\u002Fleukemia are not eligible.\n* STEP 1: CD22-positive disease defined as CD22 expression by \\>= 20% of lymphoblasts by local hematopathology evaluation.\n* STEP 1: Philadelphia chromosome\u002FBCR-ABL1-negative or Philadelphia chromosome\u002FBCR-ABL1-positive B-cell ALL by cytogenetics, fluorescence in situ hybridization (FISH), and\u002For polymerase chain reaction (PCR).\n* STEP 1: No active central nervous system (CNS) leukemia (i.e. only CNS-1 disease allowed). Active CNS leukemia is defined as morphologic evidence of lymphoblasts in the cerebrospinal fluid (CSF), use of CNS-directed local treatment for active disease within 28 days prior to registration, symptomatic CNS leukemia (i.e. cranial nerve palsies or other significant neurological dysfunction) within the 28 days prior to registration, and\u002For known asymptomatic parenchymal CNS mass lesions; see below for additional guidance. Prophylactic intrathecal medication alone is not an exclusion.\n\n  * Categories of CNS Involvement for CNS Evaluation Prior to Registration:\n\n    * CNS 1: CSF has \\\u003C 5 WBC\u002FuL with cytospin negative for blasts; or \\>= 10 red blood cell (RBC)\u002FuL with cytospin negative for blasts.\n    * CNS 2: CSF has \\\u003C 5 WBC\u002FuL with cytospin positive for blasts; or \\>= 10 RBC\u002FuL with cytospin positive for blasts; or \\>= 10 RBC\u002FuL, WBC\u002FuL \\>= 5 but less than Steinherz\u002FBleyer algorithm with cytospin positive for blasts (see below).\n    * CNS 3: CSF has \\>= 5 WBC\u002FuL with cytospin positive for blasts; or \\>= 10 RBC\u002FuL, \\>= 5 WBC\u002FuL and positive by Steinherz\u002FBleyer algorithm (see below); or clinical signs of CNS leukemia (such as facial nerve palsy, brain\u002Feye involvement or hypothalamic syndrome). Steinherz\u002FBleyer Method of Evaluating Initial Traumatic Lumbar Punctures:\n\n      * If the patient has leukemia cells in the peripheral blood and the lumbar puncture is traumatic and contains \\>= 5 WBC\u002FuL with blasts, the following algorithm should be used to define CNS disease: CSF WBC\u002FCSF RBC \\> 2 x (Blood WBC\u002FBlood RBC count)\n* STEP 1: Patients with known or suspected testicular involvement by leukemia are allowed provided that the patient receives concomitant scrotal\u002Ftesticular radiotherapy.\n\n  * Unilateral or bilateral testicular enlargement should be assessed by ultrasound or other imaging technique. Biopsy is recommended if clinical findings are equivocal or suggestive of hydrocele or a non-leukemic mass, but further assessments are per treating physician discretion.\n* STEP 1: Not pregnant and not nursing.\n\n  * This study involves agents that have known genotoxic, mutagenic, and teratogenic effects. Therefore, for women of childbearing potential only, a negative pregnancy test done =\\\u003C 7 days prior to registration is required.\n* STEP 1: Eastern Cooperative Oncology Group (ECOG) performance status: 0-2\n* STEP 1: No unstable cardiac disease such as myocardial infarction, angina pectoris, uncontrolled heart failure, or uncontrolled cardiac arrhythmia within 6 months of registration.\n* STEP 1: No impaired cardiac function, defined as left ventricular ejection fraction (LVEF) \\\u003C 45% or New York Heart Association (NYHA) stage III or IV congestive heart failure (CHF).\n* STEP 1: Patients with known human immunodeficiency virus (HIV) infection are eligible if they have been on effective antiretroviral therapy with an undetectable viral load tested within 6 months of registration.\n* STEP 1: Patients with hepatitis B virus (HBV) are eligible only if they meet all the following:\n\n  * On HBV-suppressive therapy.\n  * No evidence of active virus.\n  * No evidence of HBV-related liver damage.\n* STEP 1: Patients with hepatitis C virus (HCV) are eligible only if they meet all the following:\n\n  * Successfully completed complete-eradication therapy with undetectable viral load.\n  * No evidence of HCV-related liver damage.\n* STEP 1: No history of clinically relevant neurologic disorder such as epilepsy, seizure, aphasia, stroke, severe brain injury, structural brain abnormality, benign brain tumor, dementia, Parkinson's disease, movement disorder, cerebellar disease, or other significant CNS abnormalities.\n* STEP 1: No prior additional malignancy (i.e. in addition to ALL) except adequately treated basal- or squamous-cell skin cancer, in situ cervical cancer, stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease-free for \\>= 2 years.\n* STEP 1: No history of clinically significant ventricular arrhythmia, unexplained non-vasovagal syncope, or chronic bradycardic states such as sinoatrial block or higher degree of atrioventricular block unless a permanent pacemaker has been implanted.\n* STEP 1: No history of chronic liver disease, including cirrhosis.\n* STEP 1: No history of sinusoidal occlusion syndrome\u002Fveno-occlusive disease of the liver.\n* STEP 1: No uncontrolled infection or recent history (within 4 months prior to registration) of deep tissue infections such as fasciitis or osteomyelitis.\n* STEP 1: Total bilirubin, serum =\\\u003C 1.5 x upper limit of normal (ULN)\\*\n\n  * Except in the event of: 1) Gilbert disease, in which case total bilirubin must be =\\\u003C 2 x ULN, or 2) elevated bilirubin believed by investigator to be due to leukemic infiltration, in which case total bilirubin must be =\\\u003C 2 x ULN.\n* STEP 1: Aspartate aminotransferase (AST)\u002Falanine aminotransferase (ALT) =\\\u003C 2.5 x ULN\n* STEP 1: Creatinine, serum =\\\u003C 1.5 ULN OR creatinine clearance \\>= 40 mL\u002Fmin\n* STEP 1: QT interval by Fridericia's correction formula (QTcF) =\\\u003C 470 msec\n* COHORT 1: Age \\>= 60 years.\n* COHORT 1: Diagnosis of Philadelphia chromosome\u002FBCR-ABL1-negative B-cell ALL.\n* COHORT 1: No prior treatment for ALL except a single dose of intrathecal chemotherapy, corticosteroids, hydroxyurea, and\u002For leukapheresis to reduce peripheral blast count and prevent ALL complications. Allowed therapy may be administered for no more than 14 days and must be completed \\>= 24 hours prior to the initiation of protocol therapy.\n* COHORT 1: No plan for allogeneic or autologous hematopoietic cell transplantation (HCT).\n* COHORT 2: Age \\>= 18 years.\n* COHORT 2: Diagnosis of Philadelphia chromosome\u002FBCR-ABL1-negative B-cell ALL.\n* COHORT 2: Relapsed or refractory disease in salvage 1 or 2.\n* COHORT 2: No isolated extramedullary relapse.\n* COHORT 2: Prior allogeneic HCT permitted.\n* COHORT 2: Patients with prior allogeneic HCT must have completed transplantation \\>= 4 months prior to registration.\n* COHORT 2: Patients with prior allogeneic HCT must have no evidence of graft-versus-host disease and must have completed immunosuppressive therapy \\>= 30 days prior to registration.\n* COHORT 2: Prior treatment with inotuzumab ozogamicin, blinatumomab, other CD22-directed therapy, or other CD19-directed therapy is not allowed.\n* COHORT 2: Prior treatment with rituximab must be completed \\>= 7 days prior to registration.\n* COHORT 2: Prior treatment with other monoclonal antibodies must be completed \\>= 6 weeks prior to registration.\n* COHORT 2: Prior treatment for ALL must be completed \\>= 14 days prior to registration with the following exceptions: intrathecal chemotherapy, hydroxyurea, corticosteroids, 6-mercaptopurine, methotrexate, vincristine, and\u002For leukapheresis to reduce circulating absolute lymphoblast count to =\\\u003C 10,000\u002FuL or prevent complications related to ALL are allowed but must be completed \\>= 24 hours prior to the initiation of protocol therapy.\n* COHORT 2: Patients should have resolution of any acute non-hematologic toxicities of prior therapy to National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version (v)5.0 grade =\\\u003C 1.\n* COHORT 2: Peripheral blood absolute lymphoblast count =\\\u003C 10,000\u002FuL (treatment allowed as above to reduce blast count to =\\\u003C 10,000\u002FuL)\n* COHORT 3: Age ≥ 75 years OR age ≥ 18 years AND ineligible for hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (HyperCVAD) regimens\n* COHORT 3: Diagnosis of Philadelphia chromosome\u002FBCR-ABL1-positive B-cell ALL\n* COHORT 3: No prior treatment for ALL except a single dose of intrathecal chemotherapy, corticosteroids, hydroxyurea, BCR-ABL1-targeted tyrosine kinase inhibitor, and\u002For leukapheresis to reduce peripheral blast count and prevent ALL complications. Allowed non-protocol therapy may be administered for no more than 14 days and must be completed ≥ 24 hours prior to the initiation of protocol therapy.\n* COHORT 3: No chronic, strong CYP3A4 inducers","ALL","18 Years",{"count":2689,"type":2690},84,"ESTIMATED","INTERVENTIONAL",[2693],"PHASE2","This phase II trial studies how well inotuzumab ozogamicin and blinatumomab with or without ponatinib work in treating patients with CD22-positive B-lineage acute lymphoblastic leukemia that is newly diagnosed, has come back after a period of improvement (recurrent), or does not respond to treatment (refractory). Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a chemotherapy drug, called ozogamicin. Inotuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as CD22 receptors, and delivers ozogamicin to kill them. Blinatumomab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Ponatinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving inotuzumab ozogamicin and blinatumomab with or without ponatinib may be effective in treating patients with newly diagnosed, recurrent or refractory CD22 positive B-lineage acute lymphoblastic leukemia.",[2696,2697,2698],"B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative","Recurrent B Acute Lymphoblastic Leukemia","Refractory B Acute Lymphoblastic Leukemia","2026-09-10",{"date":2701,"type":2702},"2026-09-11","ACTUAL",{"date":2704,"type":2702},"2019-05-08",{"date":2706,"type":2690},"2027-02-01",{"name":5,"class":6},280]