[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616474":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":49,"collaborators":51,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":81,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Florida","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Crossover 1: methylphenidate, placebo","EXPERIMENTAL","methylphenidate (single dose, oral, 20 mg, immediate release) followed by placebo (single dose, oral)",[13,14],"Drug: Methylphenidate Pill","Other: Placebo Pill",{"label":16,"type":10,"description":17,"interventionNames":18},"Crossover 2: placebo, methylphenidate","placebo (single dose, oral) followed by methylphenidate (single dose, oral, 20 mg, immediate release)",[13,14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Methylphenidate Pill","Encapsulated methylphenidate",[9,16],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Placebo Pill","Encapsulated placebo",[9,16],[31],{"facility":5,"status":25,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Gainesville","Florida","32610","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-82.32483,29.65163,{"lat":41,"lon":40},[44],{"name":45,"role":46,"phone":47,"phoneExt":25,"email":48},"Amanda Elton, PhD","CONTACT","352-294-4927","amandaelton@ufl.edu",{"type":50,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[52],{"name":53,"class":54},"National Institute on Alcohol Abuse and Alcoholism (NIAAA)","NIH","100616474","phase-2-methylphenidate-and-response-to-alcohol-cues-100616474",false,"NCT07306078","Methylphenidate and Response to Alcohol Cues","Attentional Ability and Resilience to Alcohol Use Disorder: Neurocognitive Mechanisms: Protocol Two","Inclusion Criteria:\n\n* Adults ages 18-25 years\n* Meets DSM-5 criteria for Alcohol Use Disorder -OR- score on the Alcohol Use Disorders Identification Test (AUDIT) of \\>=8\n* Fluent in English\n* Normal or corrected to normal vision\n\nExclusion Criteria:\n\n* Meets DSM-5 criteria for psychotic disorders, neurological disorders, or substance use disorders other than Alcohol Use Disorder.\n* Participant routinely uses psychoactive drugs or medications except for non-dependent marijuana or nicotine use (due to common use of these substances in individuals with Alcohol Use Disorder).\n* Participant has contraindications for taking methylphenidate.\n* Participant has contraindications for being in an MRI machine\n* Self-reported history of high blood pressure over 140\u002F90 or consistent readings of 140\u002F90 or above upon arrival for a session.\n* History of seizure disorder\n* Liver disease\n* Participant is currently pregnant or trying to become pregnant",true,"ALL","18 Years","25 Years",{"count":67,"type":68},50,"ESTIMATED","INTERVENTIONAL",[71],"PHASE2","The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues. The study will observe the effects of methylphenidate or a placebo on neural and craving responses to alcohol cues through fMRI and behavioral testing. Participants will be involved in one remote and two in-person sessions.",[74],"Alcohol Use Disorder",[76,77,78,79,80],"fMRI","methylphenidate","ritalin","attention","alcohol","NOT_YET_RECRUITING","2026-08-19",{"date":84,"type":85},"2026-08-20","ACTUAL",{"date":87,"type":68},"2026-10",{"date":89,"type":68},"2028-08",{"name":5,"class":6},1]