[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659681":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":21,"studyPopulation":13,"armGroups":22,"interventions":35,"overallOfficials":44,"centralContacts":48,"locations":57,"responsibleParty":77,"collaborators":79,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":85,"sex":91,"minAge":92,"maxAge":13,"enrollmentInfo":93,"targetDuration":13,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":105,"overallStatus":111,"whyStopped":13,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Ohio State University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Center for Epidemiologic Studies Depression Scale Revised (CESD-R-10)","The Center for Epidemiologic Studies Depression Scale Revised (CESD-R-10) will be used to measure depressive symptoms.74 The CESD-R-10 is reliable (Cronbach's α = .86) and valid (convergent = .91; divergent = .89).","Baseline, 3 months, 6 months",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":17,"primaryPurpose":18,"observationalModel":13,"timePerspective":13,"maskingInfo":19},"RANDOMIZED","CROSSOVER","Pair 2 Care is an innovative, award-winning, 6-month, 100% remote (face-to-face via video such as Zoom or FaceTime, telephone, email, and text message) peer support intervention designed with and for current and former Family Caregiver Participants (FCP) of high-risk people living with AD\u002FADRD. Trained former FCP mentors provide peer mentorship to current FCPs based on their caregiving experiences and per the study protocol. The PI and project manager will conduct bimonthly research team training blitzes, including interaction scenarios, to help ensure consistency in team member interactions with participants.","SUPPORTIVE_CARE",{"masking":20,"maskingDescription":13,"whoMasked":13},"NONE","Family care partners (FCP) of older adults living with Alzheimer's disease and Alzheimer's disease-related dementias (AD\u002FADRD) are at high risk of adverse health effects of caregiving. AD\u002FADRD prevalence can be as high as 18.6% in some high-risk populations versus 10% in the general public overall. Combined with late or missed diagnosis, this leads to neuropsychological symptom management, healthcare planning, physical, spiritual, and psychosocial challenges for FCPs. Support interventions are needed to assist high-risk AD\u002FADRD FCP populations. Peer Support for Family Caregivers of Older Adults Living with Dementia (Pair 2 Care) is a peer support intervention that is delivered virtually. Our team, in collaboration with current and former FCPs, community leaders, and healthcare providers, developed Pair 2 Care. Pair 2 Care© leverages the experiential expertise of former AD\u002FADRD FCPs (care recipient is deceased) who serve as trained mentors to current FCP mentees. Pair 2 Care was found to be feasible and acceptable based on completion of total participant enrollment (N=26), mentor training, and FCP mentee-mentor pairing in only 10 weeks. Mentors were retained at 90% and FCP mentees at 93% for this 6-month intervention. Participants rated their overall Pair 2 Care satisfaction as very high (4.6\u002F5.0). We hypothesize that Pair 2 Care will result in better FCP mentee outcomes (reduced depressive symptoms, anxiety, and loneliness and greater social support, quality of life, and self-efficacy) compared to controls. We will conduct a two-arm randomized controlled trial (n=172 FCP mentees; n=86 intervention group; n=86 enhanced usual care control group). The specific aims of this study are to (1) determine Pair 2 Care intervention efficacy on FCP mentee depressive symptoms (primary outcome), anxiety, social support, loneliness, quality of life, and self-efficacy for surrogate decision making; (2) examine the associations between FCP mentee and mentor individual characteristics and variations in engagement quality (i.e., frequency and mode of connection, program satisfaction) with Pair 2 Care©; and (3) determine the impact on the mentor's well-being, identity restoration, meaning in life, and loneliness following Pair 2 Care intervention participation using mixed-methods analyses. This study will provide important intervention efficacy data for this innovative, simple, evidence-based, potentially scalable approach to addressing the needs of FCPs providing support to people living with AD\u002FADRD. Pair 2 Care has the potential to inform important AD\u002FADRD caregiving-related policy.",[23,29],{"label":24,"type":25,"description":26,"interventionNames":27},"Peer Support","EXPERIMENTAL","Former caregivers will be paired with a current caregivers",[28],"Behavioral: Peer Support",{"label":30,"type":31,"description":32,"interventionNames":33},"Active Control","ACTIVE_COMPARATOR","Participants will receive usual care conditions",[34],"Behavioral: Usual Care",[36,40],{"type":37,"name":24,"description":38,"armGroupLabels":39,"otherNames":13},"BEHAVIORAL","Former caregivers will be paired with a current caregiver based on a similar personal attribute (e.g., relationship to care recipient). Each pair will complete at least five virtual face-to-face (video) interactions and at least 10 other interactions either via phone call, email, or text messaging over the 6-month time period.",[24],{"type":37,"name":41,"description":42,"armGroupLabels":43,"otherNames":13},"Usual Care","Will include AD\u002FADRD and caregiving literature, as the control condition because it will provide a more real-world comparison. After completing the Month 6 data collection, they will be offered the Pair 2 Care intervention.",[30],[45],{"name":46,"affiliation":5,"role":47},"Karen O Moss, PhD","PRINCIPAL_INVESTIGATOR",[49,53],{"name":46,"role":50,"phone":51,"phoneExt":13,"email":52},"CONTACT","(614) 688-3100","Moss.391@osu.edu",{"name":54,"role":50,"phone":55,"phoneExt":13,"email":56},"Sandra L Solove, MA","614-247-8366","solove.3@osu.edu",[58],{"facility":59,"status":13,"city":60,"state":61,"zip":62,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":71},"Ohio State University College of Nursing","Columbus","Ohio","43210","United States","US",{"type":66,"coordinates":67},"Point",[68,69],-82.99879,39.96118,{"lat":69,"lon":68},[72,75,76],{"name":46,"role":50,"phone":73,"phoneExt":13,"email":74},"614-688-3100","moss.391@osu.edu",{"name":54,"role":50,"phone":55,"phoneExt":13,"email":56},{"name":46,"role":47,"phone":13,"phoneExt":13,"email":13},{"type":78,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR",[80],{"name":81,"class":82},"National Institute on Aging (NIA)","NIH","100659681","phase-2-peer-support-for-family-caregivers-of-older-adults-living-with-dementia-100659681",false,"NCT07868718","Peer Support for Family Caregivers of Older Adults Living With Dementia","A Randomized Controlled Trial of Peer Support for Family Caregivers of Black Older Adults Living With Dementia (Pair 2 Care)","Pair 2 Care","Inclusion Criteria:\n\n* English-speaking\n* Adult (18+)\n* Family Caregivers of people living with dementia (current or former)\n\nExclusion Criteria:\n\n* Non-English-speaking\n* Under age 18\n* Non-family caregiver","ALL","18 Years",{"count":94,"type":95},344,"ESTIMATED","INTERVENTIONAL",[98],"PHASE2","Family caregivers of people living with dementia are at high risk of poor health when caregiving for their loved one. Peer Support for Family Caregivers of Older Adults Living with Dementia (Pair 2 Care©) is a simple, nonjudgmental, flexible, and potentially scalable peer support program developed with and for family caregivers along with former (previous) caregivers, community leaders, and healthcare providers. Using the experiences of trained former caregivers as mentors to current caregiver mentees, Pair 2 Care© may lower caregiver depressive symptoms and promote health and well-being of current caregivers, their loved ones, and former caregivers while informing future Alzheimer's disease and Alzheimer's disease-related dementia caregiving policy.",[101,102,103,104],"Caregiver Burden","Caregiver Burnout","Caregiver Anxiety","Alzheimer Disease Dementia",[106,107,108,109,110],"ADRD caregivers","virtual peer-delivered intervention","Depression","Caregiver, ADRD, dementia, dementia caregiving","anxiety","NOT_YET_RECRUITING","2026-10-05",{"date":114,"type":115},"2026-10-09","ACTUAL",{"date":117,"type":95},"2026-12",{"date":119,"type":95},"2031-08",{"name":5,"class":6},1]