[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610646":3},{"organization":4,"outcomesModule":7,"designInfo":40,"detailedDescription":39,"studyPopulation":39,"armGroups":51,"interventions":64,"overallOfficials":72,"centralContacts":76,"locations":82,"responsibleParty":561,"collaborators":39,"id":563,"slug":564,"hasResults":565,"nctId":566,"briefTitle":567,"officialTitle":568,"acronym":39,"eligibilityCriteria":569,"healthyVolunteers":565,"sex":570,"minAge":571,"maxAge":39,"enrollmentInfo":572,"targetDuration":39,"studyType":575,"phases":576,"briefSummary":578,"conditions":579,"keywords":581,"overallStatus":85,"whyStopped":39,"lastUpdateSubmitDate":582,"lastUpdatePostDateStruct":583,"startDateStruct":586,"completionDateStruct":588,"leadSponsor":590,"locationsCount":591},{"fullName":5,"class":6},"AbbVie","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":39},[9,13],{"measure":10,"description":11,"timeFrame":12},"Absolute Change From Baseline in Forced Vital Capacity (FVC) (mL)","FVC is a test that measures the total amount of air a person can fully exhale from their lungs after a deep inhalation. A low FVC can demonstrate reduced lung capacity.","Week 24",{"measure":14,"description":15,"timeFrame":16},"Percentage of Participants with Adverse Events (AE)","An adverse event (AE) is defined as any untoward medical occurrence in a participant or clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with the treatment. The investigator assesses the relationship of each event to the use of study drug.","Up to approximately 52 weeks",[18,20,22,24,26,28,31,33,35,37],{"measure":10,"description":11,"timeFrame":19},"Week 52",{"measure":21,"description":11,"timeFrame":12},"Relative Change From Baseline in FVC (mL)",{"measure":23,"description":11,"timeFrame":19},"Relative Change From Baseline in FVC (ml)",{"measure":25,"description":11,"timeFrame":16},"Absolute Change from Baseline in FVC% predicted",{"measure":27,"description":11,"timeFrame":16},"Relative Change From Baseline in FVC% predicted",{"measure":29,"description":30,"timeFrame":16},"Change From Baseline in Living with Pulmonary Fibrosis (L-PF) Overall Score","L-PF questionnaire is a 49-item disease specific PRO that assesses symptoms and impacts of living with pulmonary fibrosis among participants with fibrosing interstitial lung disease (ILD). Summary scores range from 0-100, the higher the score the greater the impairment.",{"measure":32,"description":11,"timeFrame":16},"Time to First Absolute Decline From Baseline in FVC% Predicted of >= 10%",{"measure":34,"description":11,"timeFrame":16},"Time to First Relative Decline From Baseline in FVC% Predicted of >= 10%",{"measure":36,"description":11,"timeFrame":16},"Time to First Absolute Decline From Baseline in FVC% Predicted >= 5%",{"measure":38,"description":11,"timeFrame":16},"Time to First Relative Decline From Baseline in FVC% Predicted >= 5%",null,{"allocation":41,"interventionModel":42,"interventionModelDescription":39,"primaryPurpose":43,"observationalModel":39,"timePerspective":39,"maskingInfo":44},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":45,"maskingDescription":39,"whoMasked":46},"QUADRUPLE",[47,48,49,50],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR",[52,58],{"label":53,"type":54,"description":55,"interventionNames":56},"Substudy 1: ABBV-142","EXPERIMENTAL","Participants will receive ABBV-142 for 52 week during double-blind treatment period. Eligible participants may receive ABBV-142 for 52 weeks during open-label treatment period.",[57],"Drug: ABBV-142",{"label":59,"type":60,"description":61,"interventionNames":62},"Substudy 1: Placebo for ABBV-142","PLACEBO_COMPARATOR","Participants will receive placebo for ABBV-142 for 52 week during double-blind treatment period. Eligible participants may receive ABBV-142 for 52 weeks during open-label treatment period.",[57,63],"Drug: Placebo for ABBV-142",[65,69],{"type":66,"name":67,"description":67,"armGroupLabels":68,"otherNames":39},"DRUG","ABBV-142",[53,59],{"type":66,"name":70,"description":70,"armGroupLabels":71,"otherNames":39},"Placebo for ABBV-142",[59],[73],{"name":74,"affiliation":5,"role":75},"ABBVIE INC.","STUDY_DIRECTOR",[77],{"name":78,"role":79,"phone":80,"phoneExt":39,"email":81},"ABBVIE CALL CENTER","CONTACT","844-663-3742","abbvieclinicaltrials@abbvie.com",[83,97,106,116,126,136,145,155,165,175,184,196,206,217,226,235,241,246,258,270,280,292,302,312,321,330,342,354,364,373,385,395,407,418,428,437,447,458,464,473,482,488,497,503,515,525,535,541,551],{"facility":84,"status":85,"city":86,"state":87,"zip":88,"country":89,"countryCode":90,"cosmosGeoPoint":91,"geoPoint":96,"contacts":39},"The University of Alabama at Birmingham \u002FID# 277613","RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":92,"coordinates":93},"Point",[94,95],-86.80249,33.52066,{"lat":95,"lon":94},{"facility":98,"status":85,"city":99,"state":87,"zip":100,"country":89,"countryCode":90,"cosmosGeoPoint":101,"geoPoint":105,"contacts":39},"Sec Clinical Research - East - Dothan - Graceland \u002FID# 278328","Dothan","36305",{"type":92,"coordinates":102},[103,104],-85.39049,31.22323,{"lat":104,"lon":103},{"facility":107,"status":85,"city":108,"state":109,"zip":110,"country":89,"countryCode":90,"cosmosGeoPoint":111,"geoPoint":115,"contacts":39},"Clinical Research Specialists - Kissimmee \u002FID# 279184","Kissimmee","Florida","34746",{"type":92,"coordinates":112},[113,114],-81.41667,28.30468,{"lat":114,"lon":113},{"facility":117,"status":85,"city":118,"state":119,"zip":120,"country":89,"countryCode":90,"cosmosGeoPoint":121,"geoPoint":125,"contacts":39},"Christie Clinic on University \u002FID# 277871","Champaign","Illinois","61820",{"type":92,"coordinates":122},[123,124],-88.24338,40.11642,{"lat":124,"lon":123},{"facility":127,"status":85,"city":128,"state":129,"zip":130,"country":89,"countryCode":90,"cosmosGeoPoint":131,"geoPoint":135,"contacts":39},"University of Michigan Health System - Ann Arbor \u002FID# 279994","Ann Arbor","Michigan","48109",{"type":92,"coordinates":132},[133,134],-83.74088,42.27756,{"lat":134,"lon":133},{"facility":137,"status":85,"city":138,"state":129,"zip":139,"country":89,"countryCode":90,"cosmosGeoPoint":140,"geoPoint":144,"contacts":39},"Henry Ford Hospital \u002FID# 277843","Detroit","48202",{"type":92,"coordinates":141},[142,143],-83.04575,42.33143,{"lat":143,"lon":142},{"facility":146,"status":85,"city":147,"state":148,"zip":149,"country":89,"countryCode":90,"cosmosGeoPoint":150,"geoPoint":154,"contacts":39},"Hannibal Regional Hospital \u002FID# 277984","Hannibal","Missouri","63401",{"type":92,"coordinates":151},[152,153],-91.35848,39.70838,{"lat":153,"lon":152},{"facility":156,"status":85,"city":157,"state":158,"zip":159,"country":89,"countryCode":90,"cosmosGeoPoint":160,"geoPoint":164,"contacts":39},"Jefferson Health Honickman Center \u002FID# 279127","Philadelphia","Pennsylvania","19107",{"type":92,"coordinates":161},[162,163],-75.16362,39.95238,{"lat":163,"lon":162},{"facility":166,"status":85,"city":167,"state":168,"zip":169,"country":89,"countryCode":90,"cosmosGeoPoint":170,"geoPoint":174,"contacts":39},"Inova Fairfax Hospital \u002FID# 278469","Falls Church","Virginia","22042",{"type":92,"coordinates":171},[172,173],-77.17109,38.88233,{"lat":173,"lon":172},{"facility":176,"status":85,"city":177,"state":168,"zip":178,"country":89,"countryCode":90,"cosmosGeoPoint":179,"geoPoint":183,"contacts":39},"Virginia Commonwealth University Medical Center \u002FID# 277992","Richmond","23219",{"type":92,"coordinates":180},[181,182],-77.46026,37.55376,{"lat":182,"lon":181},{"facility":185,"status":85,"city":186,"state":187,"zip":188,"country":189,"countryCode":190,"cosmosGeoPoint":191,"geoPoint":195,"contacts":39},"Lung Research Queensland \u002FID# 278838","Nundah","Queensland","4012","Australia","AU",{"type":92,"coordinates":192},[193,194],153.06165,-27.40252,{"lat":194,"lon":193},{"facility":197,"status":85,"city":198,"state":199,"zip":200,"country":189,"countryCode":190,"cosmosGeoPoint":201,"geoPoint":205,"contacts":39},"Box Hill Hospital \u002FID# 278245","Melbourne","Victoria","3128",{"type":92,"coordinates":202},[203,204],144.96332,-37.814,{"lat":204,"lon":203},{"facility":207,"status":85,"city":208,"state":39,"zip":209,"country":210,"countryCode":211,"cosmosGeoPoint":212,"geoPoint":216,"contacts":39},"University Multiprofile Hospital for Active Treatment Dr. Georgi Stranski \u002FID# 277845","Pleven","5800","Bulgaria","BG",{"type":92,"coordinates":213},[214,215],24.61666,43.41791,{"lat":215,"lon":214},{"facility":218,"status":85,"city":219,"state":39,"zip":220,"country":210,"countryCode":211,"cosmosGeoPoint":221,"geoPoint":225,"contacts":39},"University Multiprofile Hospital For Active Treatment Sveti Georgi - Plovdiv \u002FID# 279367","Plovdiv","4002",{"type":92,"coordinates":222},[223,224],24.75001,42.15387,{"lat":224,"lon":223},{"facility":227,"status":85,"city":228,"state":39,"zip":229,"country":210,"countryCode":211,"cosmosGeoPoint":230,"geoPoint":234,"contacts":39},"Acibadem City Clinic Tokuda University Hospital EAD \u002FID# 277846","Sofia","1407",{"type":92,"coordinates":231},[232,233],23.32415,42.69751,{"lat":233,"lon":232},{"facility":236,"status":85,"city":228,"state":39,"zip":237,"country":210,"countryCode":211,"cosmosGeoPoint":238,"geoPoint":240,"contacts":39},"Diagnostic Consultative Center Convex \u002FID# 277848","1680",{"type":92,"coordinates":239},[232,233],{"lat":233,"lon":232},{"facility":242,"status":85,"city":228,"state":39,"zip":237,"country":210,"countryCode":211,"cosmosGeoPoint":243,"geoPoint":245,"contacts":39},"Diagnostic Consultative Center Convex \u002FID# 277849",{"type":92,"coordinates":244},[232,233],{"lat":233,"lon":232},{"facility":247,"status":85,"city":248,"state":249,"zip":250,"country":251,"countryCode":252,"cosmosGeoPoint":253,"geoPoint":257,"contacts":39},"Centre d'Investigation Clinique Mauricie \u002FID# 277949","Trois-Rivières","Quebec","G8T 7A1","Canada","CA",{"type":92,"coordinates":254},[255,256],-72.5477,46.34515,{"lat":256,"lon":255},{"facility":259,"status":85,"city":260,"state":261,"zip":262,"country":263,"countryCode":264,"cosmosGeoPoint":265,"geoPoint":269,"contacts":39},"Klinikum Konstanz \u002FID# 278139","Konstanz","Baden-Wurttemberg","78464","Germany","DE",{"type":92,"coordinates":266},[267,268],9.17582,47.66033,{"lat":268,"lon":267},{"facility":271,"status":85,"city":272,"state":273,"zip":274,"country":263,"countryCode":264,"cosmosGeoPoint":275,"geoPoint":279,"contacts":39},"Caritas-Krankenhaus St. Maria gGmbH \u002FID# 278138","Donaustauf","Bavaria","93093",{"type":92,"coordinates":276},[277,278],12.20459,49.03258,{"lat":278,"lon":277},{"facility":281,"status":85,"city":282,"state":283,"zip":284,"country":285,"countryCode":286,"cosmosGeoPoint":287,"geoPoint":291,"contacts":39},"University General Hospital of Patras \u002FID# 277726","Pátrai","Achaia","26504","Greece","GR",{"type":92,"coordinates":288},[289,290],21.73508,38.2462,{"lat":290,"lon":289},{"facility":293,"status":85,"city":294,"state":295,"zip":296,"country":285,"countryCode":286,"cosmosGeoPoint":297,"geoPoint":301,"contacts":39},"General Hospital of Chest Diseases of Athens SOTIRIA \u002FID# 277724","Athens","Attica","11527",{"type":92,"coordinates":298},[299,300],23.72784,37.98376,{"lat":300,"lon":299},{"facility":303,"status":85,"city":304,"state":305,"zip":306,"country":285,"countryCode":286,"cosmosGeoPoint":307,"geoPoint":311,"contacts":39},"University General Hospital of Heraklion \u002FID# 277717","Heraklion","Crete","71500",{"type":92,"coordinates":308},[309,310],25.14341,35.32787,{"lat":310,"lon":309},{"facility":313,"status":85,"city":314,"state":39,"zip":315,"country":285,"countryCode":286,"cosmosGeoPoint":316,"geoPoint":320,"contacts":39},"University Hospital of Ioannina \u002FID# 277719","Ioannina","45500",{"type":92,"coordinates":317},[318,319],20.85187,39.66341,{"lat":319,"lon":318},{"facility":322,"status":85,"city":323,"state":39,"zip":324,"country":285,"countryCode":286,"cosmosGeoPoint":325,"geoPoint":329,"contacts":39},"General Hospital of Thessaloniki George Papanikolaou \u002FID# 277819","Thessaloniki","57010",{"type":92,"coordinates":326},[327,328],22.93493,40.64072,{"lat":328,"lon":327},{"facility":331,"status":85,"city":332,"state":333,"zip":334,"country":335,"countryCode":336,"cosmosGeoPoint":337,"geoPoint":341,"contacts":39},"Vitamed Galaj i Cichomski Sp.j. \u002FID# 278145","Bydgoszcz","Kuyavian-Pomeranian Voivodeship","85-079","Poland","PL",{"type":92,"coordinates":338},[339,340],18.00762,53.1235,{"lat":340,"lon":339},{"facility":343,"status":85,"city":344,"state":345,"zip":346,"country":347,"countryCode":348,"cosmosGeoPoint":349,"geoPoint":353,"contacts":39},"Unidade Local de Saude de Loures-Odivelas-Hospital Beatriz Angelo \u002FID# 278357","Loures","Lisbon District","2674-514","Portugal","PT",{"type":92,"coordinates":350},[351,352],-9.16845,38.83091,{"lat":352,"lon":351},{"facility":355,"status":85,"city":356,"state":357,"zip":358,"country":347,"countryCode":348,"cosmosGeoPoint":359,"geoPoint":363,"contacts":39},"Unidade Local de Saude de Matosinhos EPE \u002FID# 277980","Senhora da Hora","Porto District","4464-513",{"type":92,"coordinates":360},[361,362],-8.65172,41.18641,{"lat":362,"lon":361},{"facility":365,"status":85,"city":366,"state":39,"zip":367,"country":347,"countryCode":348,"cosmosGeoPoint":368,"geoPoint":372,"contacts":39},"Unidade Local de Saude do Algarve, EPE \u002FID# 278388","Faro","8000-386",{"type":92,"coordinates":369},[370,371],-7.92716,37.01869,{"lat":371,"lon":370},{"facility":374,"status":85,"city":375,"state":376,"zip":377,"country":378,"countryCode":379,"cosmosGeoPoint":380,"geoPoint":384,"contacts":39},"University Clinical Center Serbia \u002FID# 278496","Belgrade","Beograd","11000","Serbia","RS",{"type":92,"coordinates":381},[382,383],20.46513,44.80401,{"lat":383,"lon":382},{"facility":386,"status":85,"city":387,"state":388,"zip":389,"country":378,"countryCode":379,"cosmosGeoPoint":390,"geoPoint":394,"contacts":39},"Institute For Pulmonary Diseases Of Vojvodina \u002FID# 278499","Kamenitz","Sremski Okrug","21208",{"type":92,"coordinates":391},[392,393],19.84263,45.22334,{"lat":393,"lon":392},{"facility":396,"status":85,"city":397,"state":398,"zip":399,"country":400,"countryCode":401,"cosmosGeoPoint":402,"geoPoint":406,"contacts":39},"Dr JM Engelbrecht Trial Site \u002FID# 278287","Somerset West","Western Cape","7130","South Africa","ZA",{"type":92,"coordinates":403},[404,405],18.82113,-34.08401,{"lat":405,"lon":404},{"facility":408,"status":85,"city":409,"state":410,"zip":411,"country":412,"countryCode":39,"cosmosGeoPoint":413,"geoPoint":417,"contacts":39},"Inje University Haeundae Paik Hospital \u002FID# 278000","Busan","Busan Gwang Yeogsi","48108","South Korea",{"type":92,"coordinates":414},[415,416],129.03004,35.10168,{"lat":416,"lon":415},{"facility":419,"status":85,"city":420,"state":421,"zip":422,"country":412,"countryCode":39,"cosmosGeoPoint":423,"geoPoint":427,"contacts":39},"The Catholic University Of Korea, Bucheon St. Mary'S Hospital \u002FID# 278068","Bucheon-si","Gyeonggido","14647",{"type":92,"coordinates":424},[425,426],126.78306,37.49889,{"lat":426,"lon":425},{"facility":429,"status":85,"city":430,"state":421,"zip":431,"country":412,"countryCode":39,"cosmosGeoPoint":432,"geoPoint":436,"contacts":39},"Seoul National University Bundang Hospital \u002FID# 278059","Seongnam-si","13620",{"type":92,"coordinates":433},[434,435],127.13778,37.43861,{"lat":435,"lon":434},{"facility":438,"status":85,"city":439,"state":440,"zip":441,"country":412,"countryCode":39,"cosmosGeoPoint":442,"geoPoint":446,"contacts":39},"Yonsei University Health System Severance Hospital \u002FID# 278166","Seoul","Seoul Teugbyeolsi","03722",{"type":92,"coordinates":443},[444,445],126.9784,37.566,{"lat":445,"lon":444},{"facility":448,"status":85,"city":449,"state":39,"zip":450,"country":451,"countryCode":452,"cosmosGeoPoint":453,"geoPoint":457,"contacts":39},"Kaohsiung Medical University Chung-Ho Memorial Hospital \u002FID# 278029","Kaohsiung City","807","Taiwan","TW",{"type":92,"coordinates":454},[455,456],120.31333,22.61626,{"lat":456,"lon":455},{"facility":459,"status":85,"city":449,"state":39,"zip":460,"country":451,"countryCode":452,"cosmosGeoPoint":461,"geoPoint":463,"contacts":39},"Kaohsiung Chang Gung Memorial Hospital \u002FID# 278043","833",{"type":92,"coordinates":462},[455,456],{"lat":456,"lon":455},{"facility":465,"status":85,"city":466,"state":39,"zip":467,"country":451,"countryCode":452,"cosmosGeoPoint":468,"geoPoint":472,"contacts":39},"China Medical University Hospital \u002FID# 278039","Taichung","40447",{"type":92,"coordinates":469},[470,471],120.6839,24.1469,{"lat":471,"lon":470},{"facility":474,"status":85,"city":475,"state":39,"zip":476,"country":451,"countryCode":452,"cosmosGeoPoint":477,"geoPoint":481,"contacts":39},"National Taiwan University Hospital \u002FID# 278041","Taipei","100",{"type":92,"coordinates":478},[479,480],121.52639,25.05306,{"lat":480,"lon":479},{"facility":483,"status":85,"city":475,"state":39,"zip":484,"country":451,"countryCode":452,"cosmosGeoPoint":485,"geoPoint":487,"contacts":39},"Taipei Veterans General Hospital \u002FID# 278038","112",{"type":92,"coordinates":486},[479,480],{"lat":480,"lon":479},{"facility":489,"status":85,"city":490,"state":39,"zip":491,"country":451,"countryCode":452,"cosmosGeoPoint":492,"geoPoint":496,"contacts":39},"Linkou Chang Gung Memorial Hospital \u002FID# 278042","Taoyuan City","333",{"type":92,"coordinates":493},[494,495],121.29696,24.99368,{"lat":495,"lon":494},{"facility":498,"status":85,"city":499,"state":500,"zip":501,"country":502,"countryCode":39,"cosmosGeoPoint":39,"geoPoint":39,"contacts":39},"Gulhane Egitim ve Arastirma Hastanesi \u002FID# 278944","Ankara","Antalya","06010","Turkey (Türkiye)",{"facility":504,"status":85,"city":505,"state":506,"zip":507,"country":508,"countryCode":509,"cosmosGeoPoint":510,"geoPoint":514,"contacts":39},"Royal Papworth Hospital NHS Foundation Trust \u002FID# 278055","Cambridge","Cambridgeshire","CB2 0AY","United Kingdom","UK",{"type":92,"coordinates":511},[512,513],0.11667,52.2,{"lat":513,"lon":512},{"facility":516,"status":85,"city":517,"state":518,"zip":519,"country":508,"countryCode":509,"cosmosGeoPoint":520,"geoPoint":524,"contacts":39},"Edinburgh Royal Infirmary - NHS Lothian \u002FID# 278631","Edinburgh","Edinburgh, City of","EH16 4SA",{"type":92,"coordinates":521},[522,523],-3.19648,55.95206,{"lat":523,"lon":522},{"facility":526,"status":85,"city":527,"state":528,"zip":529,"country":508,"countryCode":509,"cosmosGeoPoint":530,"geoPoint":534,"contacts":39},"UCLH NHS FT - University College Hospital \u002FID# 279198","London","Greater London","NW1 2BU",{"type":92,"coordinates":531},[532,533],-0.12574,51.50853,{"lat":533,"lon":532},{"facility":536,"status":85,"city":527,"state":528,"zip":537,"country":508,"countryCode":509,"cosmosGeoPoint":538,"geoPoint":540,"contacts":39},"Royal Brompton Hospital \u002FID# 278007","SW3 6NP",{"type":92,"coordinates":539},[532,533],{"lat":533,"lon":532},{"facility":542,"status":85,"city":543,"state":544,"zip":545,"country":508,"countryCode":509,"cosmosGeoPoint":546,"geoPoint":550,"contacts":39},"University Hospital Southampton \u002FID# 278223","Southampton","Hampshire","SO16 6YD",{"type":92,"coordinates":547},[548,549],-1.40428,50.90395,{"lat":549,"lon":548},{"facility":552,"status":85,"city":553,"state":554,"zip":555,"country":508,"countryCode":509,"cosmosGeoPoint":556,"geoPoint":560,"contacts":39},"Norfolk and Norwich University Hospital \u002FID# 278224","Norwich","Norfolk","NR4 7UY",{"type":92,"coordinates":557},[558,559],1.29834,52.62783,{"lat":559,"lon":558},{"type":562,"investigatorFullName":39,"investigatorTitle":39,"investigatorAffiliation":39,"oldNameTitle":39,"oldOrganization":39},"SPONSOR","100610646","phase-2-study-of-abbv-142-to-assess-adverse-events-and-change-in-disease-activity-in-adult-participants-with-idiopathic-pulmonary-fibrosis-100610646",false,"NCT07230288","Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis","A Phase 2a Multicenter Platform Study of Investigational Products for the Treatment of Adult Subjects With Idiopathic Pulmonary Fibrosis","Inclusion Criteria:\n\n\\- Diagnosis of Idiopathic Pulmonary Fibrosis (IPF) within 7 years prior to screening, confirmed by the investigator at screening that is supported by centrally read chest high-resolution computed tomography (HRCT) obtained within 12 months of the screening visit and verification of usual interstitial pneumonia(UIP) or probable UIP.\n\nExclusion Criteria:\n\n* History of stroke within 6 months prior to screening\n* In the opinion of the investigator, other clinically significant pulmonary abnormalities\n* History of any malignancy up to 5 years prior screening visit, except for successfully treated nonmelanoma skin cancer or localized carcinoma in situ of the cervix.","ALL","40 Years",{"count":573,"type":574},165,"ESTIMATED","INTERVENTIONAL",[577],"PHASE2","Idiopathic Pulmonary Fibrosis (IPF) is a rare, long-lasting lung disease that causes scarring of lung tissue, shortness of breath, and loss of lung function. IPF leads to significant loss of quality of life and shortened lifespan. This study is a platform study evaluating different types of treatments in patients with IPF. A platform study is a type of study that uses a single master protocol to evaluate different study treatments allowing for new study treatments or substudies to be added or closed over time. The main goals of the study are to evaluate the safety, tolerability (the degree to which the adverse symptoms can be handled by the patients during the study) and efficacy (how well study treatment works) of the study treatments, including ABBV-142 in Substudy 1 (SS1).\n\nABBV-142 is an investigational drug being developed for the treatment of IPF. In SS1, participants will be randomly assigned to one of the 2 groups to receive either ABBV-142 or a matching placebo. This study is \"double-blind\", meaning that neither the participants nor the study doctors know who is given which study treatment. Approximately 165 adult participants with IPF will be enrolled in approximately 125 sites across the world.\n\nParticipants will receive ABBV-142 or matching placebo for 52 weeks during the double-blind treatment period. Eligible participants may receive ABBV-142 for 52 weeks in open-label treatment period. All participants will be followed for 120 days.\n\nThere may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.",[580],"Idiopathic Pulmonary Fibrosis",[580],"2026-08-20",{"date":584,"type":585},"2026-08-24","ACTUAL",{"date":587,"type":585},"2026-01-23",{"date":589,"type":574},"2029-09",{"name":5,"class":6},49]