[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651969":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":51,"collaborators":18,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":18,"eligibilityCriteria":58,"healthyVolunteers":55,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":18,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":34,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment","EXPERIMENTAL","To receive oral L-carnitine plus standard care therapy",[13],"Drug: L- carnitine",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","To receive only standard of care therapy",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DRUG","L- carnitine","oral L-carnitine",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Mariam Hosam, Bachelor degree in Pharmacy","CONTACT","2+ 01115772704","Mariam.hossam@pharma.asu.edu.eg",[32,46],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":18},"Faculty of Pharmacy, Ain Shams University","RECRUITING","Cairo","Cairo Governorate","11566","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],31.24967,30.06263,{"lat":44,"lon":43},{"facility":33,"status":47,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":48,"geoPoint":50,"contacts":18},"ACTIVE_NOT_RECRUITING",{"type":41,"coordinates":49},[43,44],{"lat":44,"lon":43},{"type":52,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100651969","phase-2-the-effect-of-l-carnitine-on-wound-healing-in-patients-with-diabetic-foot-ulcer-100651969",false,"NCT07768228","The Effect of L-Carnitine on Wound Healing in Patients With Diabetic Foot Ulcer.","Inclusion Criteria:\n\n* Adult Male or Female patients with diabetic neuropathy mean age (30-75) years old.\n* Having Diabetic neuropathy and Diabetic foot ulcer grade 1-2 (mild- moderate) according to Wagner classification.\n* Uncontrolled diabetic patients (HbA1c). \\\u003C 9 duration of diabetic (5 - 10) years.\n* All patient treated with stable dose of anti-diabetic medication priors and during the period of the study.\n\nExclusion Criteria:\n\n* Patients with other causes of ulcers.\n* Patient taking any antioxidant supplements including vitamin E, ascorbic acid, omega 3 fatty acid, Coenzyme Q10 within three months prior to enrollment in the study.\n* Patient with autoimmune disease.\n* Patient with liver disease or kidney disease.\n* Patient taking medications for cancer.\n* Patient with thyroid disease.","ALL","30 Years","75 Years",{"count":63,"type":64},50,"ESTIMATED","INTERVENTIONAL",[67],"PHASE2","Primary outcome: To evaluate the efficacy of L-Carnitine supplementation on length and depth ulcer size\n\nSecondary outcome: To investigate the effect of L-Carnitine supplements on:\n\n1. Vascular endothelial growth factor (VEGF)\n2. Inflammatory markers TNF-a (Tumor necrosis factor alpha).\n3. Hemoglobin A1C (HbA1c) And Lipid profile (cholesterol, triglycerides, high-density Lipoprotein (HDL) and low-density lipoprotein (LDL)).\n4. To assess the type and likelihood of any adverse drug reaction that can be related to L-Carnitine supplementation.\n5. QOL (DIABETES 39)",[70,71],"Diabetic Foot Ulcer","Diabetic Foot Ulcer (DFU)",[73,70,74],"L-Carnitine","DFU","2026-08-13",{"date":77,"type":78},"2026-08-17","ACTUAL",{"date":80,"type":64},"2026-09-01",{"date":82,"type":64},"2027-08-01",{"name":5,"class":6},2]