[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607160":3},{"organization":4,"outcomesModule":7,"designInfo":74,"detailedDescription":46,"studyPopulation":46,"armGroups":85,"interventions":104,"overallOfficials":46,"centralContacts":114,"locations":121,"responsibleParty":927,"collaborators":929,"id":932,"slug":933,"hasResults":934,"nctId":935,"briefTitle":936,"officialTitle":937,"acronym":938,"eligibilityCriteria":939,"healthyVolunteers":934,"sex":940,"minAge":941,"maxAge":942,"enrollmentInfo":943,"targetDuration":46,"studyType":946,"phases":947,"briefSummary":949,"conditions":950,"keywords":46,"overallStatus":124,"whyStopped":46,"lastUpdateSubmitDate":952,"lastUpdatePostDateStruct":953,"startDateStruct":956,"completionDateStruct":958,"leadSponsor":960,"locationsCount":961},{"fullName":5,"class":6},"Sanofi","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":46},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"Co-primary endpoints US\u002FFDA: Pivotal Maintenance Sub-Study Cohort 1 Proportion of participants achieving clinical remission (CDAI) at Week 40","Clinical Remission by Crohn's Disease Activity Index (CDAI): CDAI score \\\u003C150. The CDAI is a measure of disease activity based on symptoms, signs, and a laboratory test. Scores on the CDAI scale range from 0 to 600, with scores below 150 indicating relative disease quiescence (remission), 150 to 219 indicating mild disease activity, 220 to 450 indicating moderate activity, and scores exceeding 450 indicating severe disease.","Week 40",{"measure":14,"description":15,"timeFrame":12},"Proportion of participants achieving Endoscopic Response (SES-CD) at Week 40","The SES-CD is a standardized method for evaluating disease activity. Score ranges from 0 to 56, where higher scores represent more severe disease. Endoscopic Response by SES-CD is a decrease in SES-CD ≥50% from Baseline (or a decrease of at least 2 points for participants with a Baseline score of 4 or more, and isolated ileal disease) based on central reading.",{"measure":17,"description":18,"timeFrame":12},"Co-primary endpoints EU\u002FEMA: Pivotal Maintenance Sub-Study Cohort 1 Proportion of participants achieving clinical remission per PRO-2 at Week 40","Clinical Remission 2-item patient-reported outcome (PRO-2): average daily stool frequency (SF) ≤3 and not worse than the Baseline, and average daily abdominal pain (AP) ≤1 and not worse than the Baseline.",[20,23,26,29,32,35,38,41,44,47,49,51,55,58,61,64,66,68,71],{"measure":21,"description":22,"timeFrame":12},"Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving CDAI clinical response Week 40","The CDAI is a measure of disease activity based on symptoms, signs, and a laboratory test. Scores on the CDAI scale range from 0 to 600, with scores below 150 indicating relative disease quiescence (remission), 150 to 219 indicating mild disease activity, 220 to 450 indicating moderate activity, and scores exceeding 450 indicating severe disease. Clinical Response by CDAI: decrease in CDAI score of 100 points or more from Baseline.",{"measure":24,"description":25,"timeFrame":12},"Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving SES-CD endoscopic remission at Week 40","The SES-CD is a standardized method for evaluating disease activity. Score ranges from 0 to 56, where higher scores represent more severe disease. Endoscopic remission: a SES-CD ≤4 points (SES-CD ≤2 points for isolated ileal disease) and a SES-CD decrease ≥2 points with no SES-CD sub score \\>1 point from Baseline.",{"measure":27,"description":28,"timeFrame":12},"US\u002FFDA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving CDAI clinical remission and endoscopic remission at Week 40","The CDAI is a measure of disease activity based on symptoms, signs, and a laboratory test. Scores on the CDAI scale range from 0 to 600, with scores below 150 indicating relative disease quiescence (remission), 150 to 219 indicating mild disease activity, 220 to 450 indicating moderate activity, and scores exceeding 450 indicating severe disease. The SES-CD is a standardized method for evaluating disease activity. Score ranges from 0 to 56, where higher scores represent more severe disease. Clinical Remission by CDAI: CDAI score \\\u003C150. Endoscopic remission: a SES-CD ≤4 points (SES-CD ≤2 points for isolated ileal disease) and a SES-CD decrease ≥2 points with no SES-CD sub score \\>1 point from Baseline.",{"measure":30,"description":31,"timeFrame":12},"EU\u002FEMA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving PRO-2 clinical remission and endoscopic remission at Week 40","Clinical Remission PRO-2: average daily stool frequency (SF) ≤3 and not worse than the Baseline, and average daily abdominal pain (AP) ≤1 and not worse than the Baseline. The SES-CD is a standardized method for evaluating disease activity. Score ranges from 0 to 56, where higher scores represent more severe disease. Endoscopic remission: a SES-CD ≤4 points (SES-CD ≤2 points for isolated ileal disease) and a SES-CD decrease ≥2 points with no SES-CD sub score \\>1 point from Baseline.",{"measure":33,"description":34,"timeFrame":12},"US\u002FFDA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving PRO-2 clinical remission at Week 40","Clinical Remission PRO-2: average daily stool frequency (SF) ≤3 and not worse than the Baseline, and average daily abdominal pain (AP) ≤1 and not worse than the Baseline.",{"measure":36,"description":37,"timeFrame":12},"EU\u002FEMA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving CDAI clinical remission at Week 40","Clinical Remission by CDAI: CDAI score \\\u003C150. The CDAI is a measure of disease activity based on symptoms, signs, and a laboratory test. Scores on the CDAI scale range from 0 to 600, with scores below 150 indicating relative disease quiescence (remission), 150 to 219 indicating mild disease activity, 220 to 450 indicating moderate activity, and scores exceeding 450 indicating severe disease.",{"measure":39,"description":40,"timeFrame":12},"US\u002FFDA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving corticosteroids free CDAI clinical remission at Week 40","Clinical Remission by CDAI: CDAI score \\\u003C150 and without corticosteroid use for CD for at least 12 weeks prior to assessment. The CDAI is a measure of disease activity based on symptoms, signs, and a laboratory test. Scores on the CDAI scale range from 0 to 600, with scores below 150 indicating relative disease quiescence (remission), 150 to 219 indicating mild disease activity, 220 to 450 indicating moderate activity, and scores exceeding 450 indicating severe disease.",{"measure":42,"description":43,"timeFrame":12},"EU\u002FEMA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving corticosteroids free PRO-2 remission at Week 40","Clinical Remission PRO-2: average daily stool frequency (SF) ≤3 and not worse than the Baseline, and average daily abdominal pain (AP) ≤1 and not worse than the Baseline and without corticosteroid use for CD for at least 12 weeks prior to assessment.",{"measure":45,"description":46,"timeFrame":12},"Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving ulcer-free endoscopy (in the subset of participants with ulcers at Baseline) at Week 40",null,{"measure":48,"description":37,"timeFrame":12},"US\u002FFDA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving clinical remission per CDAI at Week 40 in the subset of participants with clinical remission per CDAI at Week 0 (maintenance of clinical remission per CDAI)",{"measure":50,"description":34,"timeFrame":12},"EU\u002FEMA Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants achieving clinical remission per PRO-2 at Week 40 in the subset of participants with clinical remission per PRO-2 at Week 0 (maintenance of clinical remission per PRO-2)",{"measure":52,"description":53,"timeFrame":54},"Pivotal Maintenance Sub-Study Cohort 1: Change from Baseline in PROMIS-Fatigue Short Form 7a T-score at Week 40","The PROMIS Fatigue Short Form 7a uses a 5-point Likert scale for each of its 7 items, resulting in a raw score range of 7 to 35. This raw score is then converted into a T-score, with a mean of 50 and a standard deviation of 10, based on US national norms. Higher T-scores indicate greater fatigue.","Baseline, Week 40",{"measure":56,"description":57,"timeFrame":54},"Pivotal Maintenance Sub-Study Cohort 1: Change from Baseline in IBDQ total score at Week 40","Inflammatory Bowel Disease Questionnaire (IBDQ) instrument consist of 32 items exploring 4 dimensions: \"bowel symptoms\" (10 items), \"systemic symptoms\" (5 items), \"emotional function\" (12 items) and \"social function\" (5 items). The total IBDQ total score ranges from 32 to 224 with higher score indicating better quality of life.",{"measure":59,"description":60,"timeFrame":12},"Pivotal Maintenance Sub-Study Cohort 1: Proportion of participants with no bowel urgency by NRS at Week 40","Numeric Rating Scale (NRS) for bowel urgency measures the severity of bowel urgency-the sudden or immediate need to have a bowel movement-experienced in the past 24 hours. This tool utilizes an 11-point scale for evaluation, where 0 represents \"no urgency\" and 10 signifies the \"worst possible urgency\".",{"measure":62,"description":46,"timeFrame":63},"Pivotal Maintenance Sub-Study Cohort 1: Incidence of CD related hospitalization by Week 40","Week 0 through Week 40",{"measure":65,"description":46,"timeFrame":63},"Pivotal Maintenance Sub-Study Cohort 1: Serum concentrations of duvakitug measured over time",{"measure":67,"description":46,"timeFrame":63},"Pivotal Maintenance Sub-Study Cohort 1: Incidence of treatment-emergent antidrug antibody (ADA) against duvakitug",{"measure":69,"description":46,"timeFrame":70},"Pivotal Maintenance Sub-Study Cohort 1: Incidence of treatment-emergent adverse events (TEAEs), TEAE of special interest (TEAESIs), TE serious adverse events (TESAEs) and TEAEs leading to permanent study intervention discontinuation","Week 0 through 45 days after last dose",{"measure":72,"description":46,"timeFrame":73},"Open-Label Extension Sub-Study: Incidence of TEAEs, TEAESIs, TESAEs, and TEAEsleading to permanent study intervention discontinuation","Week 40 of pivotal maintenance through 45 days after last dose",{"allocation":75,"interventionModel":76,"interventionModelDescription":46,"primaryPurpose":77,"observationalModel":46,"timePerspective":46,"maskingInfo":78},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":79,"maskingDescription":46,"whoMasked":80},"QUADRUPLE",[81,82,83,84],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR",[86,92,96,99],{"label":87,"type":88,"description":89,"interventionNames":90},"Duvakitug dose 1","EXPERIMENTAL","Subcutaneous (SC) injection as per protocol",[91],"Drug: Duvakitug",{"label":93,"type":88,"description":94,"interventionNames":95},"Du vakitug dose 2","SC injection as per protocol",[91],{"label":97,"type":88,"description":94,"interventionNames":98},"Du vakitug dose 3",[91],{"label":100,"type":101,"description":94,"interventionNames":102},"Placebo","PLACEBO_COMPARATOR",[103],"Drug: Placebo",[105,112],{"type":106,"name":107,"description":108,"armGroupLabels":109,"otherNames":110},"DRUG","Duvakitug","Pharmaceutical form:Injection solution-Route of administration:SC injection",[93,97,87],[111],"SAR447189",{"type":106,"name":100,"description":108,"armGroupLabels":113,"otherNames":46},[100],[115],{"name":116,"role":117,"phone":118,"phoneExt":119,"email":120},"Trial Transparency email recommended (Toll free for US & Canada)","CONTACT","800-633-1610","option 6","Contact-US@sanofi.com",[122,136,146,155,161,170,179,189,199,209,218,227,236,246,255,265,273,279,285,295,304,314,320,325,334,344,353,363,373,382,391,400,409,419,428,440,444,448,459,470,481,490,501,510,519,528,539,548,557,566,576,585,596,602,608,614,620,625,637,648,657,668,677,688,697,706,717,722,728,739,750,759,768,777,786,795,806,817,826,836,845,854,860,871,877,888,894,903,912,921],{"facility":123,"status":124,"city":125,"state":126,"zip":127,"country":128,"countryCode":129,"cosmosGeoPoint":130,"geoPoint":135,"contacts":46},"Peak Gastroenterology Associates - Colorado Springs-Site Number: 8400039","RECRUITING","Colorado Springs","Colorado","80907","United States","US",{"type":131,"coordinates":132},"Point",[133,134],-104.82136,38.83388,{"lat":134,"lon":133},{"facility":137,"status":124,"city":138,"state":139,"zip":140,"country":128,"countryCode":129,"cosmosGeoPoint":141,"geoPoint":145,"contacts":46},"Clinical Research of Osceola-Site Number: 8400013","Kissimmee","Florida","34741",{"type":131,"coordinates":142},[143,144],-81.41667,28.30468,{"lat":144,"lon":143},{"facility":147,"status":124,"city":148,"state":139,"zip":149,"country":128,"countryCode":129,"cosmosGeoPoint":150,"geoPoint":154,"contacts":46},"Columbus Clinical Services LLc-Site Number: 8400038","Miami","33125",{"type":131,"coordinates":151},[152,153],-80.19366,25.77427,{"lat":153,"lon":152},{"facility":156,"status":124,"city":148,"state":139,"zip":157,"country":128,"countryCode":129,"cosmosGeoPoint":158,"geoPoint":160,"contacts":46},"Bioresearch Partner-Kendale Lakes-Site Number: 8400053","33175",{"type":131,"coordinates":159},[152,153],{"lat":153,"lon":152},{"facility":162,"status":124,"city":163,"state":139,"zip":164,"country":128,"countryCode":129,"cosmosGeoPoint":165,"geoPoint":169,"contacts":46},"Orlando Health, Inc., Digestive Health Institute-Site Number: 8400084","Orlando","32806",{"type":131,"coordinates":166},[167,168],-81.37924,28.53834,{"lat":168,"lon":167},{"facility":171,"status":124,"city":172,"state":139,"zip":173,"country":128,"countryCode":129,"cosmosGeoPoint":174,"geoPoint":178,"contacts":46},"NMC Research LLC-Site Number: 8400033","Tampa","33607",{"type":131,"coordinates":175},[176,177],-82.45843,27.94752,{"lat":177,"lon":176},{"facility":180,"status":124,"city":181,"state":182,"zip":183,"country":128,"countryCode":129,"cosmosGeoPoint":184,"geoPoint":188,"contacts":46},"Illinois Gastroenterology Group d\u002Fb\u002Fa GI Alliance - Gurnee-Site Number: 8400049","Gurnee","Illinois","60031",{"type":131,"coordinates":185},[186,187],-87.90202,42.3703,{"lat":187,"lon":186},{"facility":190,"status":124,"city":191,"state":192,"zip":193,"country":128,"countryCode":129,"cosmosGeoPoint":194,"geoPoint":198,"contacts":46},"Gastroenterology Health Partners, PLLC - New Albany-Site Number: 8400100","New Albany","Indiana","47150",{"type":131,"coordinates":195},[196,197],-85.82413,38.28562,{"lat":197,"lon":196},{"facility":200,"status":124,"city":201,"state":202,"zip":203,"country":128,"countryCode":129,"cosmosGeoPoint":204,"geoPoint":208,"contacts":46},"GI Alliance - Baton Rouge-Site Number: 8400129","Baton Rouge","Louisiana","70809",{"type":131,"coordinates":205},[206,207],-91.18747,30.44332,{"lat":207,"lon":206},{"facility":210,"status":124,"city":211,"state":202,"zip":212,"country":128,"countryCode":129,"cosmosGeoPoint":213,"geoPoint":217,"contacts":46},"Texas Digestive Disease Consultants, PLLC d\u002Fb\u002Fa GI Alliance - Mandeville-Site Number: 8400128","Mandeville","70471",{"type":131,"coordinates":214},[215,216],-90.06563,30.35825,{"lat":216,"lon":215},{"facility":219,"status":124,"city":220,"state":202,"zip":221,"country":128,"countryCode":129,"cosmosGeoPoint":222,"geoPoint":226,"contacts":46},"GI Alliance - Metairie-Site Number: 8400124","Metairie","70006",{"type":131,"coordinates":223},[224,225],-90.15285,29.98409,{"lat":225,"lon":224},{"facility":228,"status":124,"city":229,"state":202,"zip":230,"country":128,"countryCode":129,"cosmosGeoPoint":231,"geoPoint":235,"contacts":46},"Delta Research Partners-Site Number: 8400087","Monroe","71291",{"type":131,"coordinates":232},[233,234],-92.1193,32.50931,{"lat":234,"lon":233},{"facility":237,"status":124,"city":238,"state":239,"zip":240,"country":128,"countryCode":129,"cosmosGeoPoint":241,"geoPoint":245,"contacts":46},"BVL Clinical Research-Site Number: 8400005","Liberty","Missouri","64068",{"type":131,"coordinates":242},[243,244],-94.41912,39.24611,{"lat":244,"lon":243},{"facility":247,"status":124,"city":248,"state":239,"zip":249,"country":128,"countryCode":129,"cosmosGeoPoint":250,"geoPoint":254,"contacts":46},"Gateway Gastroenterology-Site Number: 8400097","St Louis","63141",{"type":131,"coordinates":251},[252,253],-90.19789,38.62727,{"lat":253,"lon":252},{"facility":256,"status":124,"city":257,"state":258,"zip":259,"country":128,"countryCode":129,"cosmosGeoPoint":260,"geoPoint":264,"contacts":46},"MedTraits NY-Site Number: 8400045","Maspeth","New York","11378",{"type":131,"coordinates":261},[262,263],-73.91264,40.72316,{"lat":263,"lon":262},{"facility":266,"status":124,"city":258,"state":258,"zip":267,"country":128,"countryCode":129,"cosmosGeoPoint":268,"geoPoint":272,"contacts":46},"NYU Langone Health-Site Number: 8400091","10016",{"type":131,"coordinates":269},[270,271],-74.00597,40.71427,{"lat":271,"lon":270},{"facility":274,"status":124,"city":258,"state":258,"zip":275,"country":128,"countryCode":129,"cosmosGeoPoint":276,"geoPoint":278,"contacts":46},"Weill Cornell Medicine - NewYork-Presbyterian Hospital-Site Number: 8400040","10065",{"type":131,"coordinates":277},[270,271],{"lat":271,"lon":270},{"facility":280,"status":124,"city":258,"state":258,"zip":281,"country":128,"countryCode":129,"cosmosGeoPoint":282,"geoPoint":284,"contacts":46},"New York Gastroenterology Associates-Site Number: 8400009","10075",{"type":131,"coordinates":283},[270,271],{"lat":271,"lon":270},{"facility":286,"status":124,"city":287,"state":288,"zip":289,"country":128,"countryCode":129,"cosmosGeoPoint":290,"geoPoint":294,"contacts":46},"UNC Hospitals, The University of North Carolina at Chapel Hill-Site Number: 8400074","Chapel Hill","North Carolina","27514",{"type":131,"coordinates":291},[292,293],-79.05584,35.9132,{"lat":293,"lon":292},{"facility":296,"status":124,"city":297,"state":288,"zip":298,"country":128,"countryCode":129,"cosmosGeoPoint":299,"geoPoint":303,"contacts":46},"Cross Creek Medical Clinic-Site Number: 8400057","Fayetteville","28304",{"type":131,"coordinates":300},[301,302],-78.87836,35.05266,{"lat":302,"lon":301},{"facility":305,"status":124,"city":306,"state":307,"zip":308,"country":128,"countryCode":129,"cosmosGeoPoint":309,"geoPoint":313,"contacts":46},"Ohio Gastroenterology Group Inc.-Site Number: 8400006","Columbus","Ohio","43202",{"type":131,"coordinates":310},[311,312],-82.99879,39.96118,{"lat":312,"lon":311},{"facility":315,"status":124,"city":306,"state":307,"zip":316,"country":128,"countryCode":129,"cosmosGeoPoint":317,"geoPoint":319,"contacts":46},"Medical Associates Research Group-Site Number: 8400063","43210",{"type":131,"coordinates":318},[311,312],{"lat":312,"lon":311},{"facility":321,"status":124,"city":306,"state":307,"zip":316,"country":128,"countryCode":129,"cosmosGeoPoint":322,"geoPoint":324,"contacts":46},"OSU Wexner Medical Center-Site Number: 8400077",{"type":131,"coordinates":323},[311,312],{"lat":312,"lon":311},{"facility":326,"status":124,"city":327,"state":307,"zip":328,"country":128,"countryCode":129,"cosmosGeoPoint":329,"geoPoint":333,"contacts":46},"North Shore Gastroenterology Research-Site Number: 8400130","Westlake","44145",{"type":131,"coordinates":330},[331,332],-81.91792,41.45532,{"lat":332,"lon":331},{"facility":335,"status":124,"city":336,"state":337,"zip":338,"country":128,"countryCode":129,"cosmosGeoPoint":339,"geoPoint":343,"contacts":46},"University of Pennsylvania School of Medicine-Site Number: 8400072","Philadelphia","Pennsylvania","19104-6243",{"type":131,"coordinates":340},[341,342],-75.16362,39.95238,{"lat":342,"lon":341},{"facility":345,"status":124,"city":346,"state":337,"zip":347,"country":128,"countryCode":129,"cosmosGeoPoint":348,"geoPoint":352,"contacts":46},"The Allegheny Health Network (AHN) Center for Digestive Health-Site Number: 8400107","Pittsburgh","15212",{"type":131,"coordinates":349},[350,351],-79.99589,40.44062,{"lat":351,"lon":350},{"facility":354,"status":124,"city":355,"state":356,"zip":357,"country":128,"countryCode":129,"cosmosGeoPoint":358,"geoPoint":362,"contacts":46},"University Gastroenterology - GI Alliance-Site Number: 8400103","Providence","Rhode Island","02904",{"type":131,"coordinates":359},[360,361],-71.41283,41.82399,{"lat":361,"lon":360},{"facility":364,"status":124,"city":365,"state":366,"zip":367,"country":128,"countryCode":129,"cosmosGeoPoint":368,"geoPoint":372,"contacts":46},"GI Alliance - Lubbock-Site Number: 8400092","Lubbock","Texas","79410",{"type":131,"coordinates":369},[370,371],-101.85517,33.57786,{"lat":371,"lon":370},{"facility":374,"status":124,"city":375,"state":366,"zip":376,"country":128,"countryCode":129,"cosmosGeoPoint":377,"geoPoint":381,"contacts":46},"SMS Clinical Research-Site Number: 8400035","Mesquite","75149",{"type":131,"coordinates":378},[379,380],-96.59916,32.7668,{"lat":380,"lon":379},{"facility":383,"status":124,"city":384,"state":366,"zip":385,"country":128,"countryCode":129,"cosmosGeoPoint":386,"geoPoint":390,"contacts":46},"Gastroenterology Research of San Antonio LLC-Site Number: 8400054","San Antonio","78229",{"type":131,"coordinates":387},[388,389],-98.49363,29.42412,{"lat":389,"lon":388},{"facility":392,"status":124,"city":393,"state":366,"zip":394,"country":128,"countryCode":129,"cosmosGeoPoint":395,"geoPoint":399,"contacts":46},"Texas Digestive Disease Consultants, PLLC. dba GI Alliance - Southlake-Site Number: 8400101","Southlake","76092",{"type":131,"coordinates":396},[397,398],-97.13418,32.94124,{"lat":398,"lon":397},{"facility":401,"status":124,"city":402,"state":366,"zip":403,"country":128,"countryCode":129,"cosmosGeoPoint":404,"geoPoint":408,"contacts":46},"Tyler Research Institute LLC-Site Number: 8400095","Tyler","75701",{"type":131,"coordinates":405},[406,407],-95.30106,32.35126,{"lat":407,"lon":406},{"facility":410,"status":124,"city":411,"state":412,"zip":413,"country":128,"countryCode":129,"cosmosGeoPoint":414,"geoPoint":418,"contacts":46},"The Vancouver Clinic Inc. P.S.-Site Number: 8400090","Vancouver","Washington","98664",{"type":131,"coordinates":415},[416,417],-122.66149,45.63873,{"lat":417,"lon":416},{"facility":420,"status":124,"city":421,"state":421,"zip":422,"country":128,"countryCode":129,"cosmosGeoPoint":423,"geoPoint":427,"contacts":46},"Gastroenterology Associates of Western Michigan-Site Number: 8400060","Wyoming","49519",{"type":131,"coordinates":424},[425,426],-105.63666,41.47747,{"lat":426,"lon":425},{"facility":429,"status":124,"city":430,"state":431,"zip":432,"country":433,"countryCode":434,"cosmosGeoPoint":435,"geoPoint":439,"contacts":46},"Investigational Site Number : 0360001","South Brisbane","Queensland","4101","Australia","AU",{"type":131,"coordinates":436},[437,438],153.02049,-27.48034,{"lat":438,"lon":437},{"facility":441,"status":124,"city":442,"state":46,"zip":443,"country":433,"countryCode":434,"cosmosGeoPoint":46,"geoPoint":46,"contacts":46},"Investigational Site Number : 0400002","Salzburg","5020",{"facility":445,"status":124,"city":446,"state":46,"zip":447,"country":433,"countryCode":434,"cosmosGeoPoint":46,"geoPoint":46,"contacts":46},"Investigational Site Number : 0400007","Vienna","1190",{"facility":449,"status":124,"city":450,"state":46,"zip":451,"country":452,"countryCode":453,"cosmosGeoPoint":454,"geoPoint":458,"contacts":46},"Investigational Site Number : 0560003","Yvoir","5530","Belgium","BE",{"type":131,"coordinates":455},[456,457],4.88059,50.3279,{"lat":457,"lon":456},{"facility":460,"status":124,"city":461,"state":46,"zip":462,"country":463,"countryCode":464,"cosmosGeoPoint":465,"geoPoint":469,"contacts":46},"Sao Jose do Rio Preto Regional Faculty of Medicine Foundation-Site Number: 0760006","São José do Rio 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