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Participants who are not able to perform the injections must receive assistance from a support person trained to administer the study intervention.\n  * store and use the provided blinded study intervention, as directed\n  * maintain electronic and paper study diaries, as applicable, and\n  * complete the required questionnaires.\n\nExclusion Criteria:\n\n* Have evidence of current or within the past 180 days prior to screening (V1), history of any substance use disorder(s) of any severity with a pattern of persistent illicit or nonprescribed substance use as indicated by clinical interview, except alcohol, nicotine, or caffeine.\n* Have answered \"yes\" to either Question 4 or Question 5 on the \"Suicidal Ideation\" portion of the Columbia-Suicide Severity Rating Scale (C-SSRS) and the ideation occurred within the past 6 months, or Have answered \"yes\" to any of the suicide-related behaviors on the \"Suicidal Behavior\" portion of the C-SSRS and the behavior occurred within the past 6 months\n* Have either of the following:\n\n  * history of advanced liver disease, including advanced liver fibrosis \\[Stage 3\\] or cirrhosis \\[Stage 4\\], based on prior biomarkers, imaging or liver biopsy, OR\n  * history of acute or alcohol-associated hepatitis based on prior liver biopsy.\n* Have participated in a clinical study and have received active treatment, or unknown if they received active treatment, within 90 days or 5 half-lives (whichever is longer) before screening (V1).","ALL","18 Years","75 Years",{"count":1414,"type":1415},1100,"ESTIMATED","INTERVENTIONAL",[1418],"PHASE3","The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with Alcohol Use Disorder (AUD) and hazardous alcohol use. Participation in this study will last approximately 56 weeks.",[1421],"Alcohol Use Disorder","2026-10-07",{"date":1424,"type":1425},"2026-10-08","ACTUAL",{"date":1427,"type":1425},"2025-10-16",{"date":1429,"type":1415},"2028-04",{"name":5,"class":6},116]