[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100508200":3},{"organization":4,"outcomesModule":7,"designInfo":42,"detailedDescription":11,"studyPopulation":11,"armGroups":53,"interventions":70,"overallOfficials":78,"centralContacts":83,"locations":87,"responsibleParty":683,"collaborators":11,"id":685,"slug":686,"hasResults":687,"nctId":688,"briefTitle":689,"officialTitle":690,"acronym":691,"eligibilityCriteria":692,"healthyVolunteers":687,"sex":693,"minAge":694,"maxAge":695,"enrollmentInfo":696,"targetDuration":11,"studyType":699,"phases":700,"briefSummary":702,"conditions":703,"keywords":11,"overallStatus":90,"whyStopped":11,"lastUpdateSubmitDate":705,"lastUpdatePostDateStruct":706,"startDateStruct":709,"completionDateStruct":711,"leadSponsor":713,"locationsCount":714},{"fullName":5,"class":6},"H. Lundbeck A\u002FS","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Change From Baseline in the Number of Monthly Migraine Days (MMDs) Averaged Over Weeks 1-12",null,"Baseline, Weeks 1-12",[14,17,20,22,24,26,28,30,32,35,38,40],{"measure":15,"description":11,"timeFrame":16},"Response: ≥50% Reduction From Baseline in MMDs","Baseline, Weeks 1-4 and Weeks 1-12",{"measure":18,"description":11,"timeFrame":19},"Percentage of Participants with Migraine on the Day After Dosing (Day 1)","On Day After Dosing",{"measure":21,"description":11,"timeFrame":12},"Change From Baseline in MMDs with Acute Medication Use",{"measure":23,"description":11,"timeFrame":16},"Response: ≥75% reduction from baseline in MMDs",{"measure":25,"description":11,"timeFrame":12},"Change From Baseline in the Number of Monthly Headache Days (MHDs)",{"measure":27,"description":11,"timeFrame":12},"Change From Baseline in Monthly Hours with Headache",{"measure":29,"description":11,"timeFrame":12},"Change From Baseline in Days with Acute Medication",{"measure":31,"description":11,"timeFrame":12},"Change From Baseline in Rate of Migraines with Severe Pain Intensity",{"measure":33,"description":11,"timeFrame":34},"Change From Baseline to Week 12 in Pediatric Migraine Disability Assessment (PedMIDAS) Score","Baseline, Week 12",{"measure":36,"description":11,"timeFrame":37},"Free Eptinezumab Plasma Concentrations","Day 0 (pre-dose) and at Weeks 8, 12, and 20",{"measure":39,"description":11,"timeFrame":37},"Number of Participants With Specific Anti-eptinezumab Antibodies (Anti-Drug Antibodies [ADA])",{"measure":41,"description":11,"timeFrame":37},"Number of Participants With Specific ADA-Positive Samples for Neutralizing Antibodies (NAb)",{"allocation":43,"interventionModel":44,"interventionModelDescription":11,"primaryPurpose":45,"observationalModel":11,"timePerspective":11,"maskingInfo":46},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":47,"maskingDescription":11,"whoMasked":48},"QUADRUPLE",[49,50,51,52],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR",[54,60,66],{"label":55,"type":56,"description":57,"interventionNames":58},"Eptinezumab 300 mg","EXPERIMENTAL","Participants will receive a single intravenous (IV) infusion of eptinezumab 300 mg (weight adjusted).",[59],"Drug: Eptinezumab",{"label":61,"type":62,"description":63,"interventionNames":64},"Placebo","PLACEBO_COMPARATOR","Participants will receive a single IV infusion of matching placebo to eptinezumab.",[65],"Drug: Placebo",{"label":67,"type":56,"description":68,"interventionNames":69},"Eptinezumab 100 mg","Participants will receive a single IV infusion of eptinezumab 100 mg (weight adjusted).",[59],[71,76],{"type":72,"name":73,"description":74,"armGroupLabels":75,"otherNames":11},"DRUG","Eptinezumab","Solution for infusion",[67,55],{"type":72,"name":61,"description":74,"armGroupLabels":77,"otherNames":11},[61],[79],{"name":80,"affiliation":81,"role":82},"Email contact via H. Lundbeck A\u002FS","HQ_Medinfo@Lundbeck.com","STUDY_DIRECTOR",[84],{"name":80,"role":85,"phone":86,"phoneExt":11,"email":81},"CONTACT","+45 36301311",[88,102,112,121,130,141,151,161,171,181,191,201,210,220,230,240,252,261,271,281,290,296,302,314,323,333,342,354,363,372,381,390,399,411,420,432,442,451,461,471,477,488,497,506,515,521,533,543,549,559,568,580,589,598,607,617,626,635,644,656,665,675],{"facility":89,"status":90,"city":91,"state":92,"zip":93,"country":94,"countryCode":95,"cosmosGeoPoint":96,"geoPoint":101,"contacts":11},"New England Institute for Clinical Research (NEICR) - Stamford","RECRUITING","Stamford","Connecticut","06905-1206","United States","US",{"type":97,"coordinates":98},"Point",[99,100],-73.53873,41.05343,{"lat":100,"lon":99},{"facility":103,"status":90,"city":104,"state":105,"zip":106,"country":94,"countryCode":95,"cosmosGeoPoint":107,"geoPoint":111,"contacts":11},"Child Neurology Center (CNC) of Northwest Florida","Gulf Breeze","Florida","32561-4458",{"type":97,"coordinates":108},[109,110],-87.16386,30.35714,{"lat":110,"lon":109},{"facility":113,"status":90,"city":114,"state":105,"zip":115,"country":94,"countryCode":95,"cosmosGeoPoint":116,"geoPoint":120,"contacts":11},"AGA Clinical Trials","Hialeah","33012-3407",{"type":97,"coordinates":117},[118,119],-80.27811,25.8576,{"lat":119,"lon":118},{"facility":122,"status":90,"city":123,"state":105,"zip":124,"country":94,"countryCode":95,"cosmosGeoPoint":125,"geoPoint":129,"contacts":11},"University of South Florida (USF) - Tampa Campus","Tampa","33620",{"type":97,"coordinates":126},[127,128],-82.45843,27.94752,{"lat":128,"lon":127},{"facility":131,"status":132,"city":133,"state":134,"zip":135,"country":94,"countryCode":95,"cosmosGeoPoint":136,"geoPoint":140,"contacts":11},"Clinical Integrative Research Center of Atlanta (CIRCAtl)","COMPLETED","Atlanta","Georgia","30328-5574",{"type":97,"coordinates":137},[138,139],-84.38798,33.749,{"lat":139,"lon":138},{"facility":142,"status":132,"city":143,"state":144,"zip":145,"country":94,"countryCode":95,"cosmosGeoPoint":146,"geoPoint":150,"contacts":11},"UK HealthCare-Kentucky Clinic","Lexington","Kentucky","40536",{"type":97,"coordinates":147},[148,149],-84.47772,37.98869,{"lat":149,"lon":148},{"facility":152,"status":132,"city":153,"state":154,"zip":155,"country":94,"countryCode":95,"cosmosGeoPoint":156,"geoPoint":160,"contacts":11},"University of Maryland School of Medicine","Baltimore","Maryland","21201-1509",{"type":97,"coordinates":157},[158,159],-76.61219,39.29038,{"lat":159,"lon":158},{"facility":162,"status":132,"city":163,"state":164,"zip":165,"country":94,"countryCode":95,"cosmosGeoPoint":166,"geoPoint":170,"contacts":11},"Michigan Headache & Neurological Institute (MHNI)","Ann Arbor","Michigan","48104-5131",{"type":97,"coordinates":167},[168,169],-83.74088,42.27756,{"lat":169,"lon":168},{"facility":172,"status":132,"city":173,"state":174,"zip":175,"country":94,"countryCode":95,"cosmosGeoPoint":176,"geoPoint":180,"contacts":11},"True North Neurology - Commack (North Suffolk Neurology)","Commack","New York","11725-2850",{"type":97,"coordinates":177},[178,179],-73.29289,40.84288,{"lat":179,"lon":178},{"facility":182,"status":132,"city":183,"state":184,"zip":185,"country":94,"countryCode":95,"cosmosGeoPoint":186,"geoPoint":190,"contacts":11},"OnSite Clinical Solutions, LLC - Charlotte","Charlotte","North Carolina","28210-0106",{"type":97,"coordinates":187},[188,189],-80.84313,35.22709,{"lat":189,"lon":188},{"facility":192,"status":90,"city":193,"state":194,"zip":195,"country":94,"countryCode":95,"cosmosGeoPoint":196,"geoPoint":200,"contacts":11},"Akron Children's Hospital","Akron","Ohio","44308-1062",{"type":97,"coordinates":197},[198,199],-81.51901,41.08144,{"lat":199,"lon":198},{"facility":202,"status":90,"city":203,"state":194,"zip":204,"country":94,"countryCode":95,"cosmosGeoPoint":205,"geoPoint":209,"contacts":11},"Cincinnati Children's Hospital Medical Center-Burnet Campus","Cincinnati","45229-3026",{"type":97,"coordinates":206},[207,208],-84.51439,39.12711,{"lat":208,"lon":207},{"facility":211,"status":90,"city":212,"state":213,"zip":214,"country":94,"countryCode":95,"cosmosGeoPoint":215,"geoPoint":219,"contacts":11},"Road Runner Research (RRR)","San Antonio","Texas","78249-3539",{"type":97,"coordinates":216},[217,218],-98.49363,29.42412,{"lat":218,"lon":217},{"facility":221,"status":90,"city":222,"state":223,"zip":224,"country":94,"countryCode":95,"cosmosGeoPoint":225,"geoPoint":229,"contacts":11},"Children's Specialty Group (CSG)","Norfolk","Virginia","23507",{"type":97,"coordinates":226},[227,228],-76.28522,36.84681,{"lat":228,"lon":227},{"facility":231,"status":90,"city":232,"state":233,"zip":234,"country":94,"countryCode":95,"cosmosGeoPoint":235,"geoPoint":239,"contacts":11},"Children's Wisconsin (Children's Hospital of Wisconsin)-Main Campus","Milwaukee","Wisconsin","53226",{"type":97,"coordinates":236},[237,238],-87.90647,43.0389,{"lat":238,"lon":237},{"facility":241,"status":90,"city":242,"state":243,"zip":244,"country":245,"countryCode":246,"cosmosGeoPoint":247,"geoPoint":251,"contacts":11},"Hospital de Niños de la Santísima Trinidad","Córdoba","Córdoba Province","X5014AKM","Argentina","AR",{"type":97,"coordinates":248},[249,250],-64.18853,-31.40648,{"lat":250,"lon":249},{"facility":253,"status":90,"city":254,"state":243,"zip":255,"country":245,"countryCode":246,"cosmosGeoPoint":256,"geoPoint":260,"contacts":11},"Instituto Médico Río Cuarto","Río Cuarto","5800",{"type":97,"coordinates":257},[258,259],-64.35272,-33.13044,{"lat":259,"lon":258},{"facility":262,"status":90,"city":263,"state":264,"zip":265,"country":245,"countryCode":246,"cosmosGeoPoint":266,"geoPoint":270,"contacts":11},"INECO Neurociencias Oroño","Rosario","Santa Fe Province","S2000DTP",{"type":97,"coordinates":267},[268,269],-60.63932,-32.94682,{"lat":269,"lon":268},{"facility":272,"status":90,"city":273,"state":274,"zip":275,"country":245,"countryCode":246,"cosmosGeoPoint":276,"geoPoint":280,"contacts":11},"Centro de Investigaciones Medicas Tucuman","San Miguel de Tucumán","Tucumán Province","T4000AXL",{"type":97,"coordinates":277},[278,279],-65.21051,-26.81601,{"lat":279,"lon":278},{"facility":282,"status":132,"city":283,"state":11,"zip":284,"country":245,"countryCode":246,"cosmosGeoPoint":285,"geoPoint":289,"contacts":11},"Clinica Independencia","Buenos Aires","1605",{"type":97,"coordinates":286},[287,288],-58.37723,-34.61315,{"lat":288,"lon":287},{"facility":291,"status":132,"city":283,"state":11,"zip":292,"country":245,"countryCode":246,"cosmosGeoPoint":293,"geoPoint":295,"contacts":11},"Mautalen Salud e Investigacion","C1128AAF",{"type":97,"coordinates":294},[287,288],{"lat":288,"lon":287},{"facility":297,"status":132,"city":283,"state":11,"zip":298,"country":245,"countryCode":246,"cosmosGeoPoint":299,"geoPoint":301,"contacts":11},"Hospital Britanico de Buenos Aires (HOB)","C1280AEB",{"type":97,"coordinates":300},[287,288],{"lat":288,"lon":287},{"facility":303,"status":132,"city":304,"state":305,"zip":306,"country":307,"countryCode":308,"cosmosGeoPoint":309,"geoPoint":313,"contacts":11},"The Medical Arts Health Research Group - Penticton","Penticton","British Columbia","V2A 5C8","Canada","CA",{"type":97,"coordinates":310},[311,312],-119.58584,49.48062,{"lat":312,"lon":311},{"facility":315,"status":90,"city":316,"state":305,"zip":317,"country":307,"countryCode":308,"cosmosGeoPoint":318,"geoPoint":322,"contacts":11},"Vancouver Island Health Authority (VIHA) - Multiple Sclerosis (MS) Clinic","Victoria","V8R 1J8",{"type":97,"coordinates":319},[320,321],-123.35155,48.4359,{"lat":321,"lon":320},{"facility":324,"status":90,"city":325,"state":326,"zip":327,"country":307,"countryCode":308,"cosmosGeoPoint":328,"geoPoint":332,"contacts":11},"Kids Clinic","Ajax","Ontario","L1Z 0M1",{"type":97,"coordinates":329},[330,331],-79.03288,43.85012,{"lat":331,"lon":330},{"facility":334,"status":90,"city":335,"state":326,"zip":336,"country":307,"countryCode":308,"cosmosGeoPoint":337,"geoPoint":341,"contacts":11},"London Health Sciences Centre (LHSC)","London","N6A 5W9",{"type":97,"coordinates":338},[339,340],-81.23304,42.98339,{"lat":340,"lon":339},{"facility":343,"status":90,"city":344,"state":345,"zip":346,"country":347,"countryCode":348,"cosmosGeoPoint":349,"geoPoint":353,"contacts":11},"L'Azienda Ospedaliera Brotzu - Clinica di Neuropsichiatria dell'Infanzia e dell'Adolescenza - Ret...","Cagliari","South Sardinia","09121","Italy","IT",{"type":97,"coordinates":350},[351,352],9.11917,39.23054,{"lat":352,"lon":351},{"facility":355,"status":90,"city":356,"state":11,"zip":357,"country":347,"countryCode":348,"cosmosGeoPoint":358,"geoPoint":362,"contacts":11},"Istituto Giannina Gaslini (Ospedale Pediatrico IRCCS) - Centro Malattie Rare","Genoa","16147",{"type":97,"coordinates":359},[360,361],8.94439,44.40478,{"lat":361,"lon":360},{"facility":364,"status":132,"city":365,"state":11,"zip":366,"country":347,"countryCode":348,"cosmosGeoPoint":367,"geoPoint":371,"contacts":11},"Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta","Milan","20133",{"type":97,"coordinates":368},[369,370],9.18951,45.46427,{"lat":370,"lon":369},{"facility":373,"status":90,"city":374,"state":11,"zip":375,"country":347,"countryCode":348,"cosmosGeoPoint":376,"geoPoint":380,"contacts":11},"Fondazione Mondino, IRCCS Istituto Neurologico Nazionale a Carattere Scientifico","Pavia","27100",{"type":97,"coordinates":377},[378,379],9.15917,45.19205,{"lat":379,"lon":378},{"facility":382,"status":90,"city":383,"state":11,"zip":384,"country":347,"countryCode":348,"cosmosGeoPoint":385,"geoPoint":389,"contacts":11},"Azienda Ospedaliero Universitaria Pisana - Stabilimento Ospedaliero di Santa Chiara - Istituto To...","Pisa","56126",{"type":97,"coordinates":386},[387,388],10.4036,43.70853,{"lat":388,"lon":387},{"facility":391,"status":90,"city":392,"state":11,"zip":393,"country":347,"countryCode":348,"cosmosGeoPoint":394,"geoPoint":398,"contacts":11},"Ospedale Pediatrico Bambino Gesu - Gianicolo","Rome","00165",{"type":97,"coordinates":395},[396,397],12.51133,41.89193,{"lat":397,"lon":396},{"facility":400,"status":132,"city":401,"state":402,"zip":403,"country":404,"countryCode":405,"cosmosGeoPoint":406,"geoPoint":410,"contacts":11},"Centro de Investigacion Clinica de Morelia, S.C.","Morelia","Michoacán","58070","Mexico","MX",{"type":97,"coordinates":407},[408,409],-101.18443,19.70078,{"lat":409,"lon":408},{"facility":412,"status":90,"city":413,"state":11,"zip":414,"country":404,"countryCode":405,"cosmosGeoPoint":415,"geoPoint":419,"contacts":11},"Clinical Research Institute SC-Mexico","Tepetlacolco","54055",{"type":97,"coordinates":416},[417,418],-97.69284,18.64104,{"lat":418,"lon":417},{"facility":421,"status":90,"city":422,"state":423,"zip":424,"country":425,"countryCode":426,"cosmosGeoPoint":427,"geoPoint":431,"contacts":11},"AthleticoMed Sp. z o.o.","Bydgoszcz","Kuyavian-Pomerania","85-752","Poland","PL",{"type":97,"coordinates":428},[429,430],18.00762,53.1235,{"lat":430,"lon":429},{"facility":433,"status":90,"city":434,"state":435,"zip":436,"country":425,"countryCode":426,"cosmosGeoPoint":437,"geoPoint":441,"contacts":11},"Centrum Medyczne Plejady Magdalena Celinska-Lowenhoff, Michal Zolnowski Spolka komandytowa","Krakow","Lesser Poland Voivodeship","30-363",{"type":97,"coordinates":438},[439,440],19.93658,50.06143,{"lat":440,"lon":439},{"facility":443,"status":90,"city":444,"state":435,"zip":445,"country":425,"countryCode":426,"cosmosGeoPoint":446,"geoPoint":450,"contacts":11},"Instytut Zdrowia dr Boczarska-Jedynak Sp. z o.o. Sp. k","Oświęcim","32-600",{"type":97,"coordinates":447},[448,449],19.21037,50.03437,{"lat":449,"lon":448},{"facility":452,"status":90,"city":453,"state":454,"zip":455,"country":425,"countryCode":426,"cosmosGeoPoint":456,"geoPoint":460,"contacts":11},"ETG Lublin","Lublin","Lublin Voivodeship","20-412",{"type":97,"coordinates":457},[458,459],22.57009,51.25058,{"lat":459,"lon":458},{"facility":462,"status":90,"city":463,"state":464,"zip":465,"country":425,"countryCode":426,"cosmosGeoPoint":466,"geoPoint":470,"contacts":11},"MTZ Clinical Research Powered by PRATIA","Warsaw","Masovian Voivodeship","02-172",{"type":97,"coordinates":467},[468,469],21.01178,52.22977,{"lat":469,"lon":468},{"facility":472,"status":90,"city":463,"state":464,"zip":473,"country":425,"countryCode":426,"cosmosGeoPoint":474,"geoPoint":476,"contacts":11},"European Trial group network Sp. z o.o - Neuroscience","02-677",{"type":97,"coordinates":475},[468,469],{"lat":469,"lon":468},{"facility":478,"status":90,"city":479,"state":11,"zip":480,"country":481,"countryCode":482,"cosmosGeoPoint":483,"geoPoint":487,"contacts":11},"Hospital de Braga","Braga","4710-367","Portugal","PT",{"type":97,"coordinates":484},[485,486],-8.42311,41.5514,{"lat":486,"lon":485},{"facility":489,"status":90,"city":490,"state":11,"zip":491,"country":481,"countryCode":482,"cosmosGeoPoint":492,"geoPoint":496,"contacts":11},"Hospital Pediátrico de Coimbra","Coimbra","3000-602",{"type":97,"coordinates":493},[494,495],-8.41996,40.20686,{"lat":495,"lon":494},{"facility":498,"status":132,"city":499,"state":11,"zip":500,"country":481,"countryCode":482,"cosmosGeoPoint":501,"geoPoint":505,"contacts":11},"Hospital CUF Descobertas, S.A.","Lisbon","1998-018",{"type":97,"coordinates":502},[503,504],-9.1498,38.72509,{"lat":504,"lon":503},{"facility":507,"status":90,"city":508,"state":11,"zip":509,"country":481,"countryCode":482,"cosmosGeoPoint":510,"geoPoint":514,"contacts":11},"Centro Hospitalar Universitario de Santo Antonio - Centro Materno Infantil do Norte (CMIN)","Porto","4050",{"type":97,"coordinates":511},[512,513],-8.61097,41.1485,{"lat":513,"lon":512},{"facility":516,"status":90,"city":508,"state":11,"zip":517,"country":481,"countryCode":482,"cosmosGeoPoint":518,"geoPoint":520,"contacts":11},"Centro Hospitalar Universitario de Sao Joao (CHUSJ)","4200-319",{"type":97,"coordinates":519},[512,513],{"lat":513,"lon":512},{"facility":522,"status":90,"city":523,"state":524,"zip":525,"country":526,"countryCode":527,"cosmosGeoPoint":528,"geoPoint":532,"contacts":11},"Univerzitetska Decija Klinika (UDK) (University Children's Hospital)","Belgrade","Beograd","11000","Serbia","RS",{"type":97,"coordinates":529},[530,531],20.46513,44.80401,{"lat":531,"lon":530},{"facility":534,"status":90,"city":535,"state":536,"zip":537,"country":526,"countryCode":527,"cosmosGeoPoint":538,"geoPoint":542,"contacts":11},"University of Novi Sad - Faculty of Medicine - Clinical Center of Vojvodina - Hematology Clinic","Novi Sad","Juznobacki Okrug","21000",{"type":97,"coordinates":539},[540,541],19.83694,45.25167,{"lat":541,"lon":540},{"facility":544,"status":90,"city":535,"state":536,"zip":545,"country":526,"countryCode":527,"cosmosGeoPoint":546,"geoPoint":548,"contacts":11},"Institute of Child and Youth Health Care of Vojvodina","21101",{"type":97,"coordinates":547},[540,541],{"lat":541,"lon":540},{"facility":550,"status":90,"city":551,"state":552,"zip":553,"country":526,"countryCode":527,"cosmosGeoPoint":554,"geoPoint":558,"contacts":11},"Clinical Center Kragujevac","Kragujevac","Sumadijski Okrug","34000",{"type":97,"coordinates":555},[556,557],20.91667,44.01667,{"lat":557,"lon":556},{"facility":560,"status":90,"city":561,"state":11,"zip":562,"country":526,"countryCode":527,"cosmosGeoPoint":563,"geoPoint":567,"contacts":11},"University Clinical Center Nis","Niš","18 000",{"type":97,"coordinates":564},[565,566],21.90333,43.32472,{"lat":566,"lon":565},{"facility":569,"status":90,"city":570,"state":571,"zip":572,"country":573,"countryCode":574,"cosmosGeoPoint":575,"geoPoint":579,"contacts":11},"Complexo Hospitalario Universitario de Vigo-Hospital Alvaro Cunqueiro (HAC)","Vigo","Pontevedra","36312","Spain","ES",{"type":97,"coordinates":576},[577,578],-8.72264,42.23282,{"lat":578,"lon":577},{"facility":581,"status":90,"city":582,"state":11,"zip":583,"country":573,"countryCode":574,"cosmosGeoPoint":584,"geoPoint":588,"contacts":11},"Hospital Universitari Vall d'Hebron","Barcelona","08035",{"type":97,"coordinates":585},[586,587],2.15899,41.38879,{"lat":587,"lon":586},{"facility":590,"status":90,"city":591,"state":11,"zip":592,"country":573,"countryCode":574,"cosmosGeoPoint":593,"geoPoint":597,"contacts":11},"Hospital Clinico San Carlos","Madrid","28040",{"type":97,"coordinates":594},[595,596],-3.70256,40.4165,{"lat":596,"lon":595},{"facility":599,"status":90,"city":600,"state":11,"zip":601,"country":573,"countryCode":574,"cosmosGeoPoint":602,"geoPoint":606,"contacts":11},"Hospital Universitari i Politecnic La Fe de Valencia (Hospital La Fe Bulevar Sur)","Valencia","46026",{"type":97,"coordinates":603},[604,605],-0.37966,39.47391,{"lat":605,"lon":604},{"facility":608,"status":90,"city":609,"state":11,"zip":610,"country":611,"countryCode":11,"cosmosGeoPoint":612,"geoPoint":616,"contacts":11},"Eskisehir Osmangazi Universitesi Tip Fakultesi Hastanesi (Eskisehir Osmangazi University Hospital)","Eskişehir","26480","Turkey (Türkiye)",{"type":97,"coordinates":613},[614,615],30.52056,39.77667,{"lat":615,"lon":614},{"facility":618,"status":90,"city":619,"state":11,"zip":620,"country":611,"countryCode":11,"cosmosGeoPoint":621,"geoPoint":625,"contacts":11},"Istanbul Universitesi - Istanbul Tip Fakultesi (ITF) Hastanesi","Istanbul","34093",{"type":97,"coordinates":622},[623,624],28.94966,41.01384,{"lat":624,"lon":623},{"facility":627,"status":90,"city":628,"state":11,"zip":629,"country":611,"countryCode":11,"cosmosGeoPoint":630,"geoPoint":634,"contacts":11},"Izmir Şehir Hastanesi","Izmir","35540",{"type":97,"coordinates":631},[632,633],27.13838,38.41273,{"lat":633,"lon":632},{"facility":636,"status":90,"city":637,"state":11,"zip":638,"country":611,"countryCode":11,"cosmosGeoPoint":639,"geoPoint":643,"contacts":11},"Mersin Universitesi-Tip Fakultesi","Mersin","33343",{"type":97,"coordinates":640},[641,642],34.63886,36.81196,{"lat":642,"lon":641},{"facility":645,"status":90,"city":646,"state":647,"zip":648,"country":649,"countryCode":650,"cosmosGeoPoint":651,"geoPoint":655,"contacts":11},"NHS Lothian - Royal Hospital for Children & Young People (RHCYP)","Edinburgh","Eastern Scotland","EH16 4TJ","United Kingdom","UK",{"type":97,"coordinates":652},[653,654],-3.19648,55.95206,{"lat":654,"lon":653},{"facility":657,"status":90,"city":658,"state":222,"zip":659,"country":649,"countryCode":650,"cosmosGeoPoint":660,"geoPoint":664,"contacts":11},"James Paget University Hospitals NHS Foundation Trust","Great Yarmouth","NR31 6LA",{"type":97,"coordinates":661},[662,663],1.73052,52.60831,{"lat":663,"lon":662},{"facility":666,"status":90,"city":667,"state":668,"zip":669,"country":649,"countryCode":650,"cosmosGeoPoint":670,"geoPoint":674,"contacts":11},"NHS Greater Glasgow and Clyde (NHSGGC) - Royal Hospital for Children - Glasgow (Royal Hospital fo...","Glasgow","South Western Scotland","G51 4TF",{"type":97,"coordinates":671},[672,673],-4.25763,55.86515,{"lat":673,"lon":672},{"facility":676,"status":90,"city":335,"state":11,"zip":677,"country":649,"countryCode":650,"cosmosGeoPoint":678,"geoPoint":682,"contacts":11},"Great Ormond Street Hospital for Children NHS Foundation Trust","WC1N 3JH",{"type":97,"coordinates":679},[680,681],-0.12574,51.50853,{"lat":681,"lon":680},{"type":684,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100508200","phase-3-a-study-of-eptinezumab-in-pediatric-participants-with-episodic-migraine-100508200",false,"NCT05897320","A Study of Eptinezumab in Pediatric Participants With Episodic Migraine","Interventional, Randomised, Double-blind, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Intravenous (IV) Eptinezumab in Paediatric Patients (6 to 17 Years) for the Preventive Treatment of Episodic Migraine","PROSPECT-1","Inclusion Criteria:\n\n* Diagnosis of migraine (with or without aura) according to the International Classification of Headache Disorders, 3rd edition (ICHD-3; in the opinion of the investigator) with history of migraine headaches of at least 6 months prior to the Screening Visit.\n* During the 28-day screening period, the participant (and their parent\u002Fcaregiver, when applicable) must adequately complete the headache eDiary (≥23 of the 28 days) following the day of the Screening Visit.\n* During the 28-day screening period, the participant must have ≤14 headache days, of which at least 4 are migraine days as documented in the eDiary.\n\nExclusion Criteria:\n\n* History or diagnosis of chronic tension-type headache, hypnic headache, cluster headache, hemicrania continua, new daily persistent headache, or unusual migraine subtypes (previously referred to as complicated migraine), such as hemiplegic migraine (sporadic and familial), migraine with brainstem aura, recurrent painful ophthalmic neuropathy, or migraine with neurological accompaniments that are not typical of migraine aura (diplopia, altered consciousness, or long duration, e.g., \\>60 min).\n* History of moderate or severe head trauma or other neurological disorder or systemic medical disease that is, in the investigator's opinion, likely to affect the functions of the central nervous system.\n* Current psychiatric condition that is uncontrolled and\u002For untreated for a minimum of 6 months prior to the Screening Visit. Participants with a lifetime history of psychosis and\u002For mania are excluded.\n* Any other disorder for which the treatment takes priority over treatment of migraine or is likely to interfere with study treatment or impair treatment compliance.\n\nOther inclusion and exclusion criteria may apply.","ALL","6 Years","17 Years",{"count":697,"type":698},315,"ESTIMATED","INTERVENTIONAL",[701],"PHASE3","The main goal of this trial is to learn whether eptinezumab helps reduce the number of days with episodic migraine in pediatric participants.",[704],"Episodic Migraine","2026-09-07",{"date":707,"type":708},"2026-09-09","ACTUAL",{"date":710,"type":708},"2023-06-08",{"date":712,"type":698},"2027-08-31",{"name":5,"class":6},62]