[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586793":3},{"organization":4,"outcomesModule":7,"designInfo":82,"detailedDescription":66,"studyPopulation":66,"armGroups":93,"interventions":112,"overallOfficials":66,"centralContacts":131,"locations":137,"responsibleParty":1439,"collaborators":66,"id":1441,"slug":1442,"hasResults":1443,"nctId":1444,"briefTitle":1445,"officialTitle":1446,"acronym":1447,"eligibilityCriteria":1448,"healthyVolunteers":1443,"sex":1449,"minAge":1450,"maxAge":66,"enrollmentInfo":1451,"targetDuration":66,"studyType":1454,"phases":1455,"briefSummary":1457,"conditions":1458,"keywords":66,"overallStatus":140,"whyStopped":66,"lastUpdateSubmitDate":1462,"lastUpdatePostDateStruct":1463,"startDateStruct":1466,"completionDateStruct":1468,"leadSponsor":1470,"locationsCount":1471},{"fullName":5,"class":6},"argenx","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":66},[9],{"measure":10,"description":11,"timeFrame":12},"Reduction of ≥1 point compared with baseline in aINCAT score at week 24","The Adjusted Inflammatory Neuropathy Cause and Treatment Disability Score (aINCAT) score is a 10-point scale that covers the functionality of legs and arms. The score varies between 0 and 10 (higher score, worse outcome).","up to 24 weeks",[14,17,20,23,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,72,74,76,78,80],{"measure":15,"description":16,"timeFrame":12},"Change from baseline in I-RODS centile points score at week 24","Inflammatory Rasch-built Overall Disability Scale (I-RODS) assesses the limitations of activities and social participation in patients with inflammatory neuropathies like CIDP. The score ranges from 0 to 100 (higher score, worse outcome).",{"measure":18,"description":19,"timeFrame":12},"Change from baseline in MRC-SS at week 24","The Medical Research Council Sum Score evaluates motor strength. Evaluated on 6 muscle groups on each side, the score varies from 0 to 60 (lower score, worse outcome).",{"measure":21,"description":22,"timeFrame":12},"Change from baseline in grip strength (3-day moving average) in the dominant hand at week 24","The grip strength will be measured daily by using a Martin-Vigorimeter. The 3 daily measurements of grip strength from the left hand and the 3 daily measurements of grip strength from the right hand will be recorded, and the daily average for the left hand and right hand will be calculated, respectively. The 3-day moving average will be generated based on the average of the obtained averages for each hand on the target day and the preceding 2 days.",{"measure":24,"description":11,"timeFrame":12},"Time to reduction of ≥1 point from baseline in aINCAT score",{"measure":26,"description":27,"timeFrame":12},"Change from baseline in TUG at week 24","The Timed Up and Go Test (TUG) is a simple test to assess a person's mobility in which the time expended to rise from a chair, walk 3 meters, turn around, walk back to the chair, and sit down is measured.",{"measure":29,"description":11,"timeFrame":30},"Time to increase of ≥1 point compared with baseline in aINCAT score","Up to 24 weeks",{"measure":32,"description":22,"timeFrame":33},"Change from baseline in grip strength (3-day moving average) of both hands over time","up to 24 weeks + 96 weeks (Part B)",{"measure":35,"description":36,"timeFrame":33},"Change from baseline in grip strength (daily average) for both hands","The grip strength will be measured daily by using a Martin-Vigorimeter. The 3 daily measurements of grip strength from the left hand and the 3 daily measurements of grip strength from the right hand will be recorded, and the daily average for the left hand and right hand will be calculated, respectively. A daily average will be generated based on the average of the obtained averages for each hand.",{"measure":38,"description":19,"timeFrame":39},"Change from baseline in MRC-SS over time","up to 96 weeks (Part B)",{"measure":41,"description":11,"timeFrame":42},"Change from baseline in aINCAT over time","up to 24 weeks (Part A) + 96 weeks (Part B)",{"measure":44,"description":45,"timeFrame":42},"Change from baseline in EQ-5D-5L over time","EQ-5D-5L questionnaire is a patient-reported outcome measure, ranging 0 to 100 (lower score, worse outcome).",{"measure":47,"description":48,"timeFrame":42},"Change from baseline in RT-FSS over time","Rasch-Transformed Fatigue Severity Scale (RT-FSS) is a patient-reported outcome measure to distinguish fatigue from clinical depression.",{"measure":50,"description":51,"timeFrame":42},"Change from baseline in SF-12 over time","12-Item Short Form Health Survey (SF-12) is a general patient-reported outcome measure.",{"measure":53,"description":54,"timeFrame":42},"Change from baseline in BPI-SF over time","The Brief Pain Inventory-Short Form (BPI-SF) is a patient-reported outcome measure to assess pain severity and pain interference.",{"measure":56,"description":57,"timeFrame":42},"PGI-S values over time","The Patient Global Impression of Severity (PGI-S) is a patient-reported outcome measure that reflects the patient's belief about the severity of the illness.",{"measure":59,"description":60,"timeFrame":42},"PGI-C values over time","The Patient Global Impression of Change (PGI-C) is a patient- reported outcome measure that reflects the patient's belief about the efficacy of treatment.",{"measure":62,"description":63,"timeFrame":12},"Values for work-related and household chore activities of the HRPQ","The Health-Related Productivity Questionnaire (HRPQ) assesses health-related and work-related productivity, with questions related to 'hours lost because of absenteeism'.",{"measure":65,"description":66,"timeFrame":12},"Percentage of scheduled hours lost in total (absenteeism+ presenteeism)",null,{"measure":68,"description":16,"timeFrame":69},"Change from baseline in I-RODS centile points score over time","Up to 96 weeks (Part B)",{"measure":71,"description":27,"timeFrame":69},"Change from baseline in TUG over time",{"measure":73,"description":66,"timeFrame":42},"Incidence of antidrug antibodies against empasiprubart in serum",{"measure":75,"description":66,"timeFrame":42},"Incidence of neutralizing antibodies against empasiprubart in serum",{"measure":77,"description":66,"timeFrame":42},"Incidence of (serious) adverse events",{"measure":79,"description":66,"timeFrame":42},"Percentage change from baseline in free C2 and total C2 over time",{"measure":81,"description":66,"timeFrame":42},"Serum concentrations of empasiprubart over time",{"allocation":83,"interventionModel":84,"interventionModelDescription":66,"primaryPurpose":85,"observationalModel":66,"timePerspective":66,"maskingInfo":86},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":87,"maskingDescription":66,"whoMasked":88},"QUADRUPLE",[89,90,91,92],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR",[94,101,108],{"label":95,"type":96,"description":97,"interventionNames":98},"Part A - empasiprubart + IVIg-placebo","EXPERIMENTAL","During Part A, participants receive empasiprubart and a placebo resembling the IVIg treatment in this arm.",[99,100],"Biological: empasiprubart","Other: IVIg-placebo",{"label":102,"type":103,"description":104,"interventionNames":105},"Part A - IVIg + empasiprubart-placebo","ACTIVE_COMPARATOR","During Part A, participants receive IVIg and a placebo resembling the empasiprubart treatment in this arm.",[106,107],"Biological: IVIg","Other: empasiprubart-placebo",{"label":109,"type":96,"description":110,"interventionNames":111},"Part B - empasiprubart","After completion of part A, participants can proceed to part B where they receive empasiprubart (no IVIg). Participants from the empasiprubart + IVIg- placebo arm in Part A will receive empasiprubart placebo once to maintain the blind of Part A.",[99,107],[113,118,122,127],{"type":114,"name":115,"description":116,"armGroupLabels":117,"otherNames":66},"BIOLOGICAL","empasiprubart","Intravenous infusion of empasiprubart",[95,109],{"type":114,"name":119,"description":120,"armGroupLabels":121,"otherNames":66},"IVIg","Intravenous infusion of IVIg",[102],{"type":123,"name":124,"description":125,"armGroupLabels":126,"otherNames":66},"OTHER","empasiprubart-placebo","A placebo resembling the empasiprubart treatment",[102,109],{"type":123,"name":128,"description":129,"armGroupLabels":130,"otherNames":66},"IVIg-placebo","A placebo resembling the IVIg treatment",[95],[132],{"name":133,"role":134,"phone":135,"phoneExt":66,"email":136},"Sabine Coppieters, MD","CONTACT","857-350-4834","clinicaltrials@argenx.com",[138,156,171,186,199,214,228,242,257,272,287,298,311,320,335,349,360,374,386,396,410,424,436,450,462,470,484,500,514,525,539,553,567,581,595,611,625,641,655,670,686,700,714,730,744,758,767,778,790,806,820,834,846,860,874,888,900,914,928,944,960,976,987,1001,1015,1026,1040,1054,1063,1073,1087,1094,1108,1124,1140,1154,1168,1184,1198,1213,1229,1245,1259,1274,1288,1299,1310,1326,1340,1354,1370,1386,1401,1413,1426],{"facility":139,"status":140,"city":141,"state":142,"zip":143,"country":144,"countryCode":145,"cosmosGeoPoint":146,"geoPoint":151,"contacts":152},"University of Alabama","RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":147,"coordinates":148},"Point",[149,150],-86.80249,33.52066,{"lat":150,"lon":149},[153],{"name":154,"role":134,"phone":135,"phoneExt":66,"email":155},"Eroboghene Ubogu, MD","ubogu@uab.edu",{"facility":157,"status":140,"city":158,"state":159,"zip":160,"country":144,"countryCode":145,"cosmosGeoPoint":161,"geoPoint":165,"contacts":166},"Samir Macwan, M.D., Inc.","Rancho Mirage","California","922701",{"type":147,"coordinates":162},[163,164],-116.41279,33.73974,{"lat":164,"lon":163},[167],{"name":168,"role":134,"phone":169,"phoneExt":66,"email":170},"Samir Macwan, MD","760-531-4068","samirmacwan@gmail.com",{"facility":172,"status":140,"city":173,"state":174,"zip":175,"country":144,"countryCode":145,"cosmosGeoPoint":176,"geoPoint":180,"contacts":181},"Colorado Springs Neurological Associates","Colorado Springs","Colorado","80907",{"type":147,"coordinates":177},[178,179],-104.82136,38.83388,{"lat":179,"lon":178},[182],{"name":183,"role":134,"phone":184,"phoneExt":66,"email":185},"David Stevens, MD","719-473-3272","dstevens@csneuro.com",{"facility":187,"status":140,"city":188,"state":189,"zip":190,"country":144,"countryCode":145,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"MedStar Washington Hospital Center","Washington D.C.","District of Columbia","20010",{"type":147,"coordinates":192},[193,194],-77.03637,38.89511,{"lat":194,"lon":193},[197],{"name":198,"role":134,"phone":135,"phoneExt":66,"email":136},"Yasir Al-Khalili, MD",{"facility":200,"status":140,"city":201,"state":202,"zip":203,"country":144,"countryCode":145,"cosmosGeoPoint":204,"geoPoint":208,"contacts":209},"Homestead Associates in Research Inc","Homestead","Florida","33033",{"type":147,"coordinates":205},[206,207],-80.47756,25.46872,{"lat":207,"lon":206},[210],{"name":211,"role":134,"phone":212,"phoneExt":66,"email":213},"Christopher Jimenez, MD","305-246-0873","cjimenez@associatesinresearch.com",{"facility":215,"status":140,"city":216,"state":202,"zip":217,"country":144,"countryCode":145,"cosmosGeoPoint":218,"geoPoint":222,"contacts":223},"Visionary Investigators Network","Miami","33133",{"type":147,"coordinates":219},[220,221],-80.19366,25.77427,{"lat":221,"lon":220},[224],{"name":225,"role":134,"phone":226,"phoneExt":66,"email":227},"Andrew Lerman, MD","786-655-8010","alerman@fcneurology.net",{"facility":229,"status":140,"city":230,"state":202,"zip":231,"country":144,"countryCode":145,"cosmosGeoPoint":232,"geoPoint":236,"contacts":237},"University of South Florida","Tampa","33616",{"type":147,"coordinates":233},[234,235],-82.45843,27.94752,{"lat":235,"lon":234},[238],{"name":239,"role":134,"phone":240,"phoneExt":66,"email":241},"Kathleen Murray, MD","813-974-9713","kmurray11@usf.edu",{"facility":243,"status":140,"city":244,"state":245,"zip":246,"country":144,"countryCode":145,"cosmosGeoPoint":247,"geoPoint":251,"contacts":252},"Paradigm Health System","Slidell","Louisiana","70458",{"type":147,"coordinates":248},[249,250],-89.78117,30.27519,{"lat":250,"lon":249},[253],{"name":254,"role":134,"phone":255,"phoneExt":66,"email":256},"Patrick Glynn, MD","985-882-4500","trickpatglynn@yahoo.com",{"facility":258,"status":140,"city":259,"state":260,"zip":261,"country":144,"countryCode":145,"cosmosGeoPoint":262,"geoPoint":266,"contacts":267},"Erlanger Health System","Columbia","Maryland","21044",{"type":147,"coordinates":263},[264,265],-76.83942,39.24038,{"lat":265,"lon":264},[268],{"name":269,"role":134,"phone":270,"phoneExt":66,"email":271},"Joshua Alpers, MD","423-778-9001","joshua.alpers@erlanger.org",{"facility":273,"status":140,"city":274,"state":275,"zip":276,"country":144,"countryCode":145,"cosmosGeoPoint":277,"geoPoint":281,"contacts":282},"University of Michigan Hospital","Ann Arbor","Michigan","48109",{"type":147,"coordinates":278},[279,280],-83.74088,42.27756,{"lat":280,"lon":279},[283],{"name":284,"role":134,"phone":285,"phoneExt":66,"email":286},"Amro Stino, MD","734-936-8586","amstino@umich.edu",{"facility":288,"status":289,"city":290,"state":291,"zip":292,"country":144,"countryCode":145,"cosmosGeoPoint":293,"geoPoint":297,"contacts":66},"University of Cincinnati Health","ACTIVE_NOT_RECRUITING","Cincinnati","Ohio","45267-2827",{"type":147,"coordinates":294},[295,296],-84.51439,39.12711,{"lat":296,"lon":295},{"facility":299,"status":140,"city":300,"state":301,"zip":302,"country":144,"countryCode":145,"cosmosGeoPoint":303,"geoPoint":307,"contacts":308},"Perelman Center for Advanced Medicine","Philadelphia","Pennsylvania","19104-5127",{"type":147,"coordinates":304},[305,306],-75.16362,39.95238,{"lat":306,"lon":305},[309],{"name":310,"role":134,"phone":135,"phoneExt":66,"email":136},"Michael Baer, MD",{"facility":312,"status":140,"city":300,"state":301,"zip":313,"country":144,"countryCode":145,"cosmosGeoPoint":314,"geoPoint":316,"contacts":317},"Jefferson Health Honickman Center","19107",{"type":147,"coordinates":315},[305,306],{"lat":306,"lon":305},[318],{"name":319,"role":134,"phone":135,"phoneExt":66,"email":136},"Goran Rakocevic, MD",{"facility":321,"status":140,"city":322,"state":323,"zip":324,"country":144,"countryCode":145,"cosmosGeoPoint":325,"geoPoint":329,"contacts":330},"NeuroCarePlus","Houston","Texas","77094",{"type":147,"coordinates":326},[327,328],-95.36327,29.76328,{"lat":328,"lon":327},[331],{"name":332,"role":134,"phone":333,"phoneExt":66,"email":334},"Nicolas Nammour, MD","281-579-6800","nicolas.nammour@sclamanagement.com",{"facility":336,"status":140,"city":337,"state":323,"zip":338,"country":144,"countryCode":145,"cosmosGeoPoint":339,"geoPoint":343,"contacts":344},"National Neuromuscular Research Institute","Irving","75063",{"type":147,"coordinates":340},[341,342],-96.94889,32.81402,{"lat":342,"lon":341},[345],{"name":346,"role":134,"phone":347,"phoneExt":66,"email":348},"Yessar Hussain, MD","512-920-0140","yessar@austinneuromuscle.com",{"facility":350,"status":289,"city":351,"state":66,"zip":352,"country":353,"countryCode":354,"cosmosGeoPoint":355,"geoPoint":359,"contacts":66},"Instituto Privado Kremer","Córdoba","X5004AOA","Argentina","AR",{"type":147,"coordinates":356},[357,358],-64.18853,-31.40648,{"lat":358,"lon":357},{"facility":361,"status":140,"city":362,"state":66,"zip":363,"country":353,"countryCode":354,"cosmosGeoPoint":364,"geoPoint":368,"contacts":369},"INECO Neurociencias Oroño","Rosario","S2000DTP",{"type":147,"coordinates":365},[366,367],-60.63932,-32.94682,{"lat":367,"lon":366},[370],{"name":371,"role":134,"phone":372,"phoneExt":66,"email":373},"Darío Tavolini, MD","+5493420000000","dtavolini@inecoorono.org",{"facility":375,"status":289,"city":376,"state":377,"zip":378,"country":379,"countryCode":380,"cosmosGeoPoint":381,"geoPoint":385,"contacts":66},"Liverpool Hospital","Liverpool","New South Wales","2179","Australia","AU",{"type":147,"coordinates":382},[383,384],150.92588,-33.91938,{"lat":384,"lon":383},{"facility":387,"status":289,"city":388,"state":66,"zip":66,"country":389,"countryCode":390,"cosmosGeoPoint":391,"geoPoint":395,"contacts":66},"Kepler Universitätsklinikum Linz - Med Campus III","Linz","Austria","AT",{"type":147,"coordinates":392},[393,394],14.28611,48.30639,{"lat":394,"lon":393},{"facility":397,"status":140,"city":398,"state":66,"zip":399,"country":389,"countryCode":390,"cosmosGeoPoint":400,"geoPoint":404,"contacts":405},"Universitätsklinikum AKH Wien","Vienna","1090",{"type":147,"coordinates":401},[402,403],16.37208,48.20849,{"lat":403,"lon":402},[406],{"name":407,"role":134,"phone":408,"phoneExt":66,"email":409},"Jakob Rath, MD","+4314040031170","jakob.rath@meduniwien.ac.at",{"facility":411,"status":140,"city":412,"state":66,"zip":413,"country":414,"countryCode":415,"cosmosGeoPoint":416,"geoPoint":420,"contacts":421},"PSEG Centro de Pesquisa Clinica","São Paulo","04038-002","Brazil","BR",{"type":147,"coordinates":417},[418,419],-46.63611,-23.5475,{"lat":419,"lon":418},[422],{"name":423,"role":134,"phone":135,"phoneExt":66,"email":136},"Paulo Sgobbi de Souza, MD",{"facility":425,"status":289,"city":426,"state":427,"zip":428,"country":429,"countryCode":430,"cosmosGeoPoint":431,"geoPoint":435,"contacts":66},"Black Tusk Research Group","Vancouver","British Columbia","V6Z2C7","Canada","CA",{"type":147,"coordinates":432},[433,434],-123.11934,49.24966,{"lat":434,"lon":433},{"facility":437,"status":140,"city":438,"state":66,"zip":439,"country":440,"countryCode":441,"cosmosGeoPoint":442,"geoPoint":446,"contacts":447},"Hospital Universitario San Ignacio","Bogotá","110231","Colombia","CO",{"type":147,"coordinates":443},[444,445],-74.08175,4.60971,{"lat":445,"lon":444},[448],{"name":449,"role":134,"phone":135,"phoneExt":66,"email":136},"Alba Lucia Marentes Cubillos, MD",{"facility":451,"status":140,"city":452,"state":66,"zip":453,"country":440,"countryCode":441,"cosmosGeoPoint":454,"geoPoint":458,"contacts":459},"Hospital Alma Máter de Antioquia","Medellín","50012",{"type":147,"coordinates":455},[456,457],-75.57151,6.245,{"lat":457,"lon":456},[460],{"name":461,"role":134,"phone":135,"phoneExt":66,"email":136},"Juan Gomez, MD",{"facility":463,"status":140,"city":452,"state":66,"zip":453,"country":440,"countryCode":441,"cosmosGeoPoint":464,"geoPoint":466,"contacts":467},"Hospital Neurologico de Colombia Fundacion Ivan Jimenez - El Neurologico",{"type":147,"coordinates":465},[456,457],{"lat":457,"lon":456},[468],{"name":469,"role":134,"phone":135,"phoneExt":66,"email":136},"Lina Maria Agudelo Ramos, MD",{"facility":471,"status":140,"city":472,"state":66,"zip":66,"country":473,"countryCode":66,"cosmosGeoPoint":474,"geoPoint":478,"contacts":479},"Fakultni nemocnice Brno","Brno","Czechia",{"type":147,"coordinates":475},[476,477],16.60796,49.19522,{"lat":477,"lon":476},[480],{"name":481,"role":134,"phone":482,"phoneExt":66,"email":483},"Magda Horakova, MD","+420734427851","horakova.magda@fnbrno.cz",{"facility":485,"status":140,"city":486,"state":66,"zip":487,"country":488,"countryCode":489,"cosmosGeoPoint":490,"geoPoint":494,"contacts":495},"Astra Kliinik","Tallinn","11315","Estonia","EE",{"type":147,"coordinates":491},[492,493],24.75353,59.43696,{"lat":493,"lon":492},[496],{"name":497,"role":134,"phone":498,"phoneExt":66,"email":499},"Katrin Gross-Paju, MD","+37253323052","katrin.gross-paju@astrakliinik.ee",{"facility":501,"status":140,"city":502,"state":66,"zip":503,"country":488,"countryCode":489,"cosmosGeoPoint":504,"geoPoint":508,"contacts":509},"Tartu University Hospital","Tartu","50406",{"type":147,"coordinates":505},[506,507],26.72509,58.38062,{"lat":507,"lon":506},[510],{"name":511,"role":134,"phone":512,"phoneExt":66,"email":513},"Liis Väli, MD","+3727318543","Liis.Vali@kliinikum.ee",{"facility":515,"status":289,"city":516,"state":516,"zip":517,"country":518,"countryCode":519,"cosmosGeoPoint":520,"geoPoint":524,"contacts":66},"AP-HP - Hôpital de la Pitié Salpétrière","Paris","75013","France","FR",{"type":147,"coordinates":521},[522,523],2.3488,48.85341,{"lat":523,"lon":522},{"facility":526,"status":140,"city":527,"state":66,"zip":528,"country":518,"countryCode":519,"cosmosGeoPoint":529,"geoPoint":533,"contacts":534},"CHU de Bordeaux - Hôpital Pellegrin","Bordeaux","33076",{"type":147,"coordinates":530},[531,532],-0.58046,44.84124,{"lat":532,"lon":531},[535],{"name":536,"role":134,"phone":537,"phoneExt":66,"email":538},"Gwendal Le Masson, MD","+33557821392","gwendal.le-masson@chu-bordeaux.fr",{"facility":540,"status":140,"city":541,"state":66,"zip":542,"country":518,"countryCode":519,"cosmosGeoPoint":543,"geoPoint":547,"contacts":548},"AP-HP - Hôpital Bicêtre","Le Kremlin-Bicêtre","94270",{"type":147,"coordinates":544},[545,546],2.36073,48.81471,{"lat":546,"lon":545},[549],{"name":550,"role":134,"phone":551,"phoneExt":66,"email":552},"Andoni Echaniz-Laguna, MD","+33145213159","andoni.echaniz-laguna@aphp.fr",{"facility":554,"status":140,"city":555,"state":66,"zip":556,"country":518,"countryCode":519,"cosmosGeoPoint":557,"geoPoint":561,"contacts":562},"CHU de Nice-Hôpital Pasteur","Nice","6001",{"type":147,"coordinates":558},[559,560],7.26608,43.70313,{"lat":560,"lon":559},[563],{"name":564,"role":134,"phone":565,"phoneExt":66,"email":566},"Sabrina Sacconi, MD","+33492035757","sacconi.s@chu-nice.fr",{"facility":568,"status":140,"city":569,"state":66,"zip":570,"country":518,"countryCode":519,"cosmosGeoPoint":571,"geoPoint":575,"contacts":576},"CHU de Strasbourg - Hôpital de 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Maribor","Maribor","2000",{"type":147,"coordinates":1250},[1251,1252],15.64593,46.55583,{"lat":1252,"lon":1251},[1255],{"name":1256,"role":134,"phone":1257,"phoneExt":66,"email":1258},"Timotej Petrijan, MD","+38623212364","timotej.petrijan@ukc-mb.si",{"facility":1260,"status":140,"city":1261,"state":66,"zip":1262,"country":1263,"countryCode":66,"cosmosGeoPoint":1264,"geoPoint":1268,"contacts":1269},"Inje University Haeundae Paik Hospital","Busan","48108","South Korea",{"type":147,"coordinates":1265},[1266,1267],129.03004,35.10168,{"lat":1267,"lon":1266},[1270],{"name":1271,"role":134,"phone":1272,"phoneExt":66,"email":1273},"Kyong Jin Shin, MD","+82517972080","neurof@naver.com",{"facility":1275,"status":140,"city":1276,"state":66,"zip":1277,"country":1263,"countryCode":66,"cosmosGeoPoint":1278,"geoPoint":1282,"contacts":1283},"Seoul National University Hospital","Seoul","03080",{"type":147,"coordinates":1279},[1280,1281],126.9784,37.566,{"lat":1281,"lon":1280},[1284],{"name":1285,"role":134,"phone":1286,"phoneExt":66,"email":1287},"Sung Min Kim, MD","+82220727312","sueh916@gmail.com",{"facility":1289,"status":140,"city":1276,"state":66,"zip":1290,"country":1263,"countryCode":66,"cosmosGeoPoint":1291,"geoPoint":1293,"contacts":1294},"Severance Hospital Yonsei University Health System","03722",{"type":147,"coordinates":1292},[1280,1281],{"lat":1281,"lon":1280},[1295],{"name":1296,"role":134,"phone":1297,"phoneExt":66,"email":1298},"Ha Young Shin, MD","+82222281600","hayshin@yuhs.ac",{"facility":1300,"status":140,"city":1276,"state":66,"zip":1301,"country":1263,"countryCode":66,"cosmosGeoPoint":1302,"geoPoint":1304,"contacts":1305},"Konkuk University Medical Center","05030",{"type":147,"coordinates":1303},[1280,1281],{"lat":1281,"lon":1280},[1306],{"name":1307,"role":134,"phone":1308,"phoneExt":66,"email":1309},"Jee Young Oh, 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MD","+34934896000","raul.juntas@vallhebron.cat",{"facility":1341,"status":140,"city":1342,"state":66,"zip":1343,"country":1314,"countryCode":1315,"cosmosGeoPoint":1344,"geoPoint":1348,"contacts":1349},"Hospital Universitario Virgen Macarena","Seville","41009",{"type":147,"coordinates":1345},[1346,1347],-5.97317,37.38283,{"lat":1347,"lon":1346},[1350],{"name":1351,"role":134,"phone":1352,"phoneExt":66,"email":1353},"Eva Maria Martínez Fernández, MD","+34600162109","emmartinezf@yahoo.es",{"facility":1355,"status":140,"city":1356,"state":66,"zip":1357,"country":1358,"countryCode":1359,"cosmosGeoPoint":1360,"geoPoint":1364,"contacts":1365},"Sahlgrenska University Hospital","Gothenburg","41346","Sweden","SE",{"type":147,"coordinates":1361},[1362,1363],11.96679,57.70716,{"lat":1363,"lon":1362},[1366],{"name":1367,"role":134,"phone":1368,"phoneExt":66,"email":1369},"Lenka Novakova Nyren, MD","+46313424107","lenka.novakova@vgregion.se",{"facility":1371,"status":140,"city":1372,"state":66,"zip":1373,"country":1374,"countryCode":1375,"cosmosGeoPoint":1376,"geoPoint":1380,"contacts":1381},"Hôpitaux Universitaires de Genève (HUG)","Geneva","1205","Switzerland","CH",{"type":147,"coordinates":1377},[1378,1379],6.14569,46.20222,{"lat":1379,"lon":1378},[1382],{"name":1383,"role":134,"phone":1384,"phoneExt":66,"email":1385},"Agustina Lascano, MD","+41223725283","agustina.lascano@hcuge.ch",{"facility":1387,"status":140,"city":1388,"state":66,"zip":1389,"country":1390,"countryCode":66,"cosmosGeoPoint":1391,"geoPoint":1395,"contacts":1396},"Ondokuz Mayis Universitesi Saglik Uygulama ve Arastirma Merkezi","Samsun","55200","Turkey (Türkiye)",{"type":147,"coordinates":1392},[1393,1394],36.3361,41.27976,{"lat":1394,"lon":1393},[1397],{"name":1398,"role":134,"phone":1399,"phoneExt":66,"email":1400},"Murat Terzi, MD","+905323000000","mterzi@omu.edu.tr",{"facility":1402,"status":289,"city":1403,"state":1404,"zip":1405,"country":1406,"countryCode":1407,"cosmosGeoPoint":1408,"geoPoint":1412,"contacts":66},"Salford Royal Hospital - PPDS","Salford","Lancashire","M6 8HD","United Kingdom","UK",{"type":147,"coordinates":1409},[1410,1411],-2.29042,53.48771,{"lat":1411,"lon":1410},{"facility":1414,"status":140,"city":1415,"state":66,"zip":1416,"country":1406,"countryCode":1407,"cosmosGeoPoint":1417,"geoPoint":1421,"contacts":1422},"Leeds General Infirmary","Leeds","LS1 3EX",{"type":147,"coordinates":1418},[1419,1420],-1.54785,53.79648,{"lat":1420,"lon":1419},[1423],{"name":1424,"role":134,"phone":66,"phoneExt":66,"email":1425},"Priya Shanmugarajah, MD","priya.shanmugarajah@nhs.net",{"facility":1427,"status":140,"city":1428,"state":66,"zip":1429,"country":1406,"countryCode":1407,"cosmosGeoPoint":1430,"geoPoint":1434,"contacts":1435},"The National Hospital for Neurology and Neurosurgery - PPDS","London","WC1N 3BG",{"type":147,"coordinates":1431},[1432,1433],-0.12574,51.50853,{"lat":1433,"lon":1432},[1436],{"name":1437,"role":134,"phone":66,"phoneExt":66,"email":1438},"Junie (Shiwen) Koay, MD","shiwen.koay@nhs.net",{"type":1440,"investigatorFullName":66,"investigatorTitle":66,"investigatorAffiliation":66,"oldNameTitle":66,"oldOrganization":66},"SPONSOR","100586793","phase-3-a-study-to-assess-efficacy-and-safety-of-empasiprubart-versus-ivig-in-adults-with-cidp-100586793",false,"NCT06920004","A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP","A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Intravenous Empasiprubart Versus Intravenous Immunoglobulin in Adults With Chronic Inflammatory Demyelinating Polyneuropathy","emvigorate","Inclusion Criteria:\n\n* Meets criteria for CIDP based on EAN\u002FPNS Task Force CIDP guidelines, second revision (2021)\n* Has either typical CIDP or 1 of the following CIDP variants: motor CIDP, multifocal CIDP (also known as Lewis-Sumner syndrome), focal CIDP, or distal CIDP\n* Has responded to IVIg in the past 5 years\n* Receiving treatment with IVIg within a standard optimal maintenance dosing regimen, with a minimum weekly IVIg dose of at least 0.125 g\u002Fkg\n* Has residual disability and active disease\n\nExclusion Criteria:\n\n* Besides the indication under study, known autoimmune disease or any medical condition that would interfere with an accurate assessment of clinical symptoms of CIDP or puts the participant at undue risk, including polyneuropathy of other causes\n* Meets the criteria for possible or sensory CIDP based on EAN\u002FPNS Task Force CIDP guidelines, second revision (2021)\n* Use of other long-acting immunomodulatory treatment","ALL","18 Years",{"count":1452,"type":1453},218,"ESTIMATED","INTERVENTIONAL",[1456],"PHASE3","The main purpose of this study is to compare empasiprubart and IVIg for treating people with CIDP. This study consists of a Part A where participants will either receive empasiprubart and a placebo resembling IVIg, or IVIg and a placebo resembling empasiprubart for 24 weeks (6 months). Following Part A, participants will enter Part B in which all participants will receive empasiprubart for 96 weeks (24 months).\n\nMore information can be found here: https:\u002F\u002Fclinicaltrials.argenx.com\u002Femvigorate",[1459,1460,1461],"Chronic Inflammatory Demyelinating Polyneuropathy","CIDP","CIDP - Chronic Inflammatory Demyelinating Polyneuropathy","2026-09-16",{"date":1464,"type":1465},"2026-09-17","ACTUAL",{"date":1467,"type":1465},"2025-08-22",{"date":1469,"type":1453},"2030-09",{"name":5,"class":6},95]