[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644599":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":42,"centralContacts":46,"locations":54,"responsibleParty":215,"collaborators":41,"id":217,"slug":218,"hasResults":219,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":41,"eligibilityCriteria":223,"healthyVolunteers":219,"sex":224,"minAge":225,"maxAge":41,"enrollmentInfo":226,"targetDuration":41,"studyType":229,"phases":230,"briefSummary":232,"conditions":233,"keywords":41,"overallStatus":57,"whyStopped":41,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":246},{"fullName":5,"class":6},"Hoffmann-La Roche","INDUSTRY",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Enicepatide Dose 1","EXPERIMENTAL","Participants will receive enicepatide Dose 1.",[13],"Combination Product: 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Medicine","200336",{"type":64,"coordinates":180},[167,168],{"lat":168,"lon":167},{"facility":183,"status":57,"city":163,"state":41,"zip":184,"country":61,"countryCode":62,"cosmosGeoPoint":185,"geoPoint":187,"contacts":41},"Shanghai Fifth People's Hospital Affiliated to Fudan University","201304",{"type":64,"coordinates":186},[167,168],{"lat":168,"lon":167},{"facility":189,"status":57,"city":190,"state":41,"zip":191,"country":61,"countryCode":62,"cosmosGeoPoint":192,"geoPoint":196,"contacts":41},"Shenyang Fifth People Hospital","Shenyang","110074",{"type":64,"coordinates":193},[194,195],123.43278,41.79222,{"lat":195,"lon":194},{"facility":198,"status":57,"city":199,"state":41,"zip":200,"country":61,"countryCode":62,"cosmosGeoPoint":201,"geoPoint":205,"contacts":41},"Hebei Medical University - The Second Hospital","Shijiazhuang","050004",{"type":64,"coordinates":202},[203,204],114.47861,38.04139,{"lat":204,"lon":203},{"facility":207,"status":57,"city":208,"state":41,"zip":209,"country":61,"countryCode":62,"cosmosGeoPoint":210,"geoPoint":214,"contacts":41},"Zibo Municipal Hospital.","Zibo","255400",{"type":64,"coordinates":211},[212,213],118.06333,36.79056,{"lat":213,"lon":212},{"type":216,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR","100644599","phase-3-a-study-to-evaluate-the-effects-of-enicepatide-in-participants-with-obesity-or-overweight-with-or-without-type-2-diabetes-100644599",false,"NCT07670416","A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or Overweight, With or Without Type 2 Diabetes","A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once-Weekly RO7795068 in Adult Chinese Patients 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History of acute or chronic pancreatitis or clinically significant gallbladder disease\n* Treatment with any approved or investigational GLP-1-RA-based therapy within 6 months prior to randomization\n* Treatment with other investigational therapy within 3 months prior to randomization or less than 5 elimination half-lives prior to randomization, whichever is longer\n* Known allergy to any component of the study drug formulation or any other condition that is a contraindication to GLP-1 RAs or GLP-1\u002FGIP RAs","ALL","18 Years",{"count":227,"type":228},300,"ESTIMATED","INTERVENTIONAL",[231],"PHASE3","The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)\u002Fglucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA) being developed for chronic weight management, as an adjunct to a reduced-calorie diet and increased physical activity in participants without Type 2 diabetes mellitus (T2DM) who have obesity or overweight with at least one weight-related comorbidity, and in participants with T2DM who have obesity or overweight.",[234,235,236],"Obesity","Overweight","Type 2 Diabetes Mellitus (T2DM)","2026-08-12",{"date":239,"type":240},"2026-08-13","ACTUAL",{"date":242,"type":240},"2026-07-03",{"date":244,"type":228},"2028-03-15",{"name":5,"class":6},18]