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Lifting Outcomes Of Moms","A Randomized, Blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Oral LPCN 1154A in Women With Postpartum Depression","BLOOM","Key Inclusion Criteria:\n\n* Are female between 15 and 45 years of age, inclusive;\n* Have had a depressive episode that began no earlier than second trimester and no later than the first 4 weeks following delivery\n* Are \\\u003C 18 months postpartum at Screening\n* Hamilton Depression Rating Scale (HAM-D) 17-item score indicative of severe depression\n\nKey Exclusion Criteria:\n\n* Have a history of bipolar disorder, schizophrenia or schizoaffective disorder\n* Are currently experiencing active psychosis per Investigator assessment\n* Have a history of suicidal behavior associated with the current depressive episode\n* Have a history of seizure within six months of Screening","FEMALE","15 Years","45 Years",{"count":224,"type":225},120,"ESTIMATED","INTERVENTIONAL",[228],"PHASE3","The purpose of this research 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The trial aims to determine:\n\n* If LPCN 1154A reduces depressive symptoms in subjects with severe PPD\n* How well LPCN 1154A is tolerated and what side effects it may cause",[231,232,233,234,235,236],"Depression, Postpartum","Postpartum Depression (PPD)","Post-partum Depression","Postnatal Depression","Post-Natal Depression","Peripartum Depression",[238,239,240,47,241,242,243],"Postpartum Depression","PPD","Depression","brexanolone","neuroactive steriod","GABAA","2026-09-10",{"date":246,"type":247},"2026-09-16","ACTUAL",{"date":249,"type":225},"2026-09",{"date":251,"type":225},"2027-09",{"name":5,"class":6},16]