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below.","CONTACT","888-662-6728","global-roche-genentech-trials@gene.com",{"name":135,"role":131,"phone":11,"phoneExt":11,"email":11},"Fastest response: use the inquiry form. https:\u002F\u002Fwww.gene.com\u002Fcontact-us\u002Fsubmit-medical-inquiry",[137,151,160,170,180,190,200,209,219,229,241,252,264,276,286,296,306,316,322,331,340,349,355,364,373,382,392,401,412,421,432,441,447,456,465,474,483,494,500,509,520,529,538,547,559,569,578,590,599,603,607,616,625,634,643,652,661,665,674,683,695,699,708,712,723,728,737,743,749,755,761,773,783,792,801],{"facility":138,"status":139,"city":140,"state":141,"zip":142,"country":143,"countryCode":144,"cosmosGeoPoint":145,"geoPoint":150,"contacts":11},"City of Hope National Medical Center","RECRUITING","Duarte","California","91010-3012","United 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Hospital","Numakunai","028-3695",{"type":146,"coordinates":630},[631,632],141.21667,39.96667,{"lat":632,"lon":631},{"facility":635,"status":139,"city":636,"state":11,"zip":637,"country":583,"countryCode":584,"cosmosGeoPoint":638,"geoPoint":642,"contacts":11},"National Hospital Organization Okayama Medical Center","Okayama","701-1192",{"type":146,"coordinates":639},[640,641],133.93333,34.65,{"lat":641,"lon":640},{"facility":644,"status":139,"city":645,"state":11,"zip":646,"country":583,"countryCode":584,"cosmosGeoPoint":647,"geoPoint":651,"contacts":11},"Osaka University Hospital","Osaka","565-0871",{"type":146,"coordinates":648},[649,650],135.50107,34.69379,{"lat":650,"lon":649},{"facility":653,"status":139,"city":654,"state":11,"zip":655,"country":583,"countryCode":584,"cosmosGeoPoint":656,"geoPoint":660,"contacts":11},"Dokkyo Medical University Saitama Medical Center","Saitama","343-8555",{"type":146,"coordinates":657},[658,659],139.65657,35.90807,{"lat":659,"lon":658},{"facility":662,"status":139,"city":663,"state":11,"zip":664,"country":583,"countryCode":584,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"Japanese Red Cross Medical Center","Shibuya-ku","150-8935",{"facility":666,"status":139,"city":667,"state":11,"zip":668,"country":583,"countryCode":584,"cosmosGeoPoint":669,"geoPoint":673,"contacts":11},"The Cancer Institute Hospital of JFCR","Tokyo","135-8550",{"type":146,"coordinates":670},[671,672],139.69171,35.6895,{"lat":672,"lon":671},{"facility":675,"status":139,"city":676,"state":11,"zip":677,"country":583,"countryCode":584,"cosmosGeoPoint":678,"geoPoint":682,"contacts":11},"Yamagata University Hospital","Yamagata","990-9585",{"type":146,"coordinates":679},[680,681],140.36667,38.23333,{"lat":681,"lon":680},{"facility":684,"status":139,"city":685,"state":686,"zip":687,"country":688,"countryCode":689,"cosmosGeoPoint":690,"geoPoint":694,"contacts":11},"SP ZOZ Szpital Uniwersytecki w Krakowie-Jakubowskiego 2;Oddzial Kliniczny Hematologii","Krakow","Lesser Poland Voivodeship","30-688","Poland","PL",{"type":146,"coordinates":691},[692,693],19.93658,50.06143,{"lat":693,"lon":692},{"facility":696,"status":139,"city":697,"state":11,"zip":698,"country":688,"countryCode":689,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"Uniwersyteckie Centrum Kliniczne","Gda?sk","80-214",{"facility":700,"status":139,"city":701,"state":11,"zip":702,"country":688,"countryCode":689,"cosmosGeoPoint":703,"geoPoint":707,"contacts":11},"Narodowy Instytut Onkologii im. Marii Sk?odowskiej-Curie - Pa?stwowy Instytut Badawczy","Warsaw","02-721",{"type":146,"coordinates":704},[705,706],21.01178,52.22977,{"lat":706,"lon":705},{"facility":709,"status":139,"city":710,"state":11,"zip":711,"country":688,"countryCode":689,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu","Wroc?aw","50-367",{"facility":713,"status":139,"city":714,"state":11,"zip":715,"country":716,"countryCode":717,"cosmosGeoPoint":718,"geoPoint":722,"contacts":11},"Auxilio Mutuo Cancer Center","San Juan","917","Puerto Rico","PR",{"type":146,"coordinates":719},[720,721],-66.10572,18.46633,{"lat":721,"lon":720},{"facility":724,"status":139,"city":725,"state":11,"zip":726,"country":727,"countryCode":11,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"Chonnam National University Hwasun Hospital","Jeollanam-do","58128","South Korea",{"facility":729,"status":139,"city":730,"state":11,"zip":731,"country":727,"countryCode":11,"cosmosGeoPoint":732,"geoPoint":736,"contacts":11},"Seoul National University 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Mary's Hospital","06591",{"type":146,"coordinates":759},[734,735],{"lat":735,"lon":734},{"facility":762,"status":139,"city":763,"state":764,"zip":765,"country":766,"countryCode":767,"cosmosGeoPoint":768,"geoPoint":772,"contacts":11},"Hospital Costa del Sol","Marbella","Malaga","29603","Spain","ES",{"type":146,"coordinates":769},[770,771],-4.88583,36.51543,{"lat":771,"lon":770},{"facility":774,"status":139,"city":775,"state":776,"zip":777,"country":766,"countryCode":767,"cosmosGeoPoint":778,"geoPoint":782,"contacts":11},"Clinica Universitaria de Navarra","Pamplona","Navarre","31008",{"type":146,"coordinates":779},[780,781],-1.64323,42.81687,{"lat":781,"lon":780},{"facility":784,"status":139,"city":785,"state":11,"zip":786,"country":766,"countryCode":767,"cosmosGeoPoint":787,"geoPoint":791,"contacts":11},"Hospital Clinic i Provincial de Barcelona","Barcelona","08036",{"type":146,"coordinates":788},[789,790],2.15899,41.38879,{"lat":790,"lon":789},{"facility":793,"status":139,"city":794,"state":11,"zip":795,"country":766,"countryCode":767,"cosmosGeoPoint":796,"geoPoint":800,"contacts":11},"Hospital General Universitario Gregorio Marañon","Madrid","28009",{"type":146,"coordinates":797},[798,799],-3.70256,40.4165,{"lat":799,"lon":798},{"facility":802,"status":139,"city":803,"state":11,"zip":804,"country":766,"countryCode":767,"cosmosGeoPoint":805,"geoPoint":809,"contacts":11},"Hospital Clinico Universitario de Salamanca","Salamanca","37007",{"type":146,"coordinates":806},[807,808],-5.66388,40.96882,{"lat":808,"lon":807},{"type":811,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100635688","phase-3-cevostamab-in-combination-with-pomalidomide-and-dexamethasone-versus-standard-of-care-in-participants-with-previously-treated-multiple-myeloma-100635688",false,"NCT07555938","Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma","A Phase III, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Patients With Multiple Myeloma Who Have Received One to Three Prior Lines of Therapy","CEVOLUTION","Inclusion Criteria:\n\n* Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1 at screening and immediately prior to start of administration of study treatment.\n* Individuals with ECOG Performance Status of 2 solely due to local symptoms of myeloma (e.g., pain) are eligible\n* MM diagnosis according to the International Myeloma Working Group (IMWG) diagnostic criteria\n* Received one to three lines of prior therapy that included at least two consecutive cycles of either of the following: A regimen containing an anti-CD38 therapy, a regimen containing lenalidomide\n* Participants must have measurable disease during screening\n\nExclusion Criteria:\n\n* Known history of amyloidosis (e.g., positive Congo Red stain or equivalent in tissue biopsy or documented within serum amyloid P component scan)\n* Plasma cell leukemia or circulating plasma cell count exceeding 500 cells\u002Fliter (L) or 5% of the peripheral blood white cells\n* GI disease that might significantly alter absorption of oral drugs\n* Participants must not have any ongoing CNS disease or non-secretory myeloma","ALL","18 Years",{"count":823,"type":824},380,"ESTIMATED","INTERVENTIONAL",[827],"PHASE3","The purpose of this study is to assess the efficacy and safety of cevostamab in combination with pomalidomide and dexamethasone (CevosPd) versus standard of care (SOC) in participants with multiple myeloma (MM) who have received one to three prior lines of therapy and have been exposed to an anti-CD38 monoclonal antibody (mAb) and lenalidomide.",[830],"Multiple Myeloma","2026-09-10",{"date":833,"type":834},"2026-09-11","ACTUAL",{"date":836,"type":834},"2026-06-23",{"date":838,"type":824},"2033-01-31",{"name":5,"class":6},75]