[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641552":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":26,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":26,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Tanta University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lidocaine group","EXPERIMENTAL","IV lidocaine 1.5 mg\u002Fkg (diluted with 0.9% isotonic saline to a total volume of 10 ml) over 5 minutes with the start of skin incision",[13],"Drug: Lidocaine IV",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","PLACEBO_COMPARATOR","IV 10 ml isotonic saline over the same period",[19],"Other: Saline 0.9%",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Lidocaine IV","IV lidocaine 1.5 mg\u002Fkg (diluted with 0.9% isotonic saline to a total volume of 10 ml) over 5 minutes with the start of skin incision after ensuring negative baseline headache.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Saline 0.9%","IV 10 ml isotonic saline over 5 minutes with the start of skin incision after ensuring negative baseline headache.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Osama M Rehab, MD","CONTACT","+201095210806","osamarehab@med.tanta.edu.eg",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Tanta University Hospitals","RECRUITING","Tanta","Gharbia Governorate","31527","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.00192,30.78847,{"lat":50,"lon":49},[53],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Osama Rehab","lecturer of anesthesiology, surgical intensive care and pain medicine Tanta university","100641552","phase-3-intravenous-lidocaine-to-prevent-post-fundal-pressure-headache-during-cesarean-section-100641552",false,"NCT07661758","Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean Section","Pre-emptive Single Intravenous Lidocaine Dose to Prevent Post-Fundal Pressure Headache During Cesarean Section: The LID-HEAD Multi-center Randomized Controlled Trial","LID-HEAD","Inclusion Criteria:\n\n* Aged ≥ 18 years\n* American Society of Anesthesiologists (ASA) Physical Status II\n* Scheduled for elective cesarean section under spinal anesthesia\n\nExclusion Criteria:\n\n* Patients declined to participate in the trial,\n* Patients with history of any type of headache, mental illness, or cerebrovascular diseases\n* Previous epidural insertion for painless labor or any other indications;\n* Patients on opioid or analgesic medications;\n* Those with pregnancy-induced hypertension or diabetic patients,\n* Allergy to lidocaine;\n* Contraindication or failure of spinal anesthesia.","FEMALE","18 Years",{"count":69,"type":70},680,"ESTIMATED","INTERVENTIONAL",[73],"PHASE3","This prospective randomized controlled multicenter study will be conducted to evaluate the effects of pre-emptive IV lidocaine dose on the incidence and severity of intraoperative headache that may occur after the extra-abdominal manual uterine fundal pressure in patients undergoing cesarean section under spinal anesthesia.",[76,77,78],"Intravenous Lidocaine","Fundal Pressure","Headache","2026-07-01",{"date":81,"type":82},"2026-07-06","ACTUAL",{"date":79,"type":82},{"date":85,"type":70},"2026-11-02",{"name":5,"class":6},1]