[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646025":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":37,"centralContacts":42,"locations":50,"responsibleParty":70,"collaborators":72,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":30,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":30,"overallStatus":107,"whyStopped":30,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Johns Hopkins Bloomberg School of Public Health","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Iron (60 mg)- folic acid (400 ug) [IFA]","ACTIVE_COMPARATOR","Weekly IFA will be provided in the control arm as standard-of-care for a year as per government of Bangladesh policy and WHO guidelines for this age group.",[13],"Dietary Supplement: Iron (60 mg)- folic acid (400 ug) [IFA]",{"label":15,"type":16,"description":17,"interventionNames":18},"Multiple micronutrient supplement [MMS]","EXPERIMENTAL","A daily MMS supplement containing 15 micronutrients using the UNIMMAP (United Nations International Multiple Micronutrient Antenatal Preparation) formulation. This will be provided in a daily tablet form for a year.",[19],"Dietary Supplement: Multiple micronutrient supplement [MMS]",{"label":21,"type":16,"description":22,"interventionNames":23},"Multiple micronutrient supplement Plus [MMS+]","MMS+ will be a package of nutrient supplements comprising the UNIMMAP tablet and a lipid-based chickpea product with choline, calcium and additional vitamin D taken daily for a year, plus a local DHA\u002FEPA softgel taken three times a week for a year.",[24],"Dietary Supplement: Multiple micronutrient supplement Plus [MMS+]",[26,31,34],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"DIETARY_SUPPLEMENT","Weekly IFA will be provided in the control arm as standard-of-care for a year",[9],null,{"type":27,"name":15,"description":32,"armGroupLabels":33,"otherNames":30},"Experimental: Multiple micronutrient supplement \\[MMS\\] A daily MMS supplement containing 15 micronutrients using the UNIMMAP (United Nations International Multiple Micronutrient Antenatal Preparation) formulation. This will be provided in a daily tablet form for a year.",[15],{"type":27,"name":21,"description":35,"armGroupLabels":36,"otherNames":30},"Experimental: Multiple micronutrient supplement Plus \\[MMS+\\] MMS+ will be a package of nutrient supplements comprising the UNIMMAP tablet, plus a lipid-based chickpea product with choline, calcium and additional vitamin D, plus a local DHA\u002FEPA softgel taken daily for a year.",[21],[38],{"name":39,"affiliation":40,"role":41},"Parul Christian, DrPH","Johns Hopkins University","PRINCIPAL_INVESTIGATOR",[43,47],{"name":39,"role":44,"phone":45,"phoneExt":30,"email":46},"CONTACT","14109552061","pchrist1@jhu.edu",{"name":48,"role":44,"phone":30,"phoneExt":30,"email":49},"Daniel Erchick, PhD","derchick@jhu.edu",[51],{"facility":52,"status":30,"city":53,"state":30,"zip":30,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"JiVitA Project Head Quarters","Rangpur City","Bangladesh","BD",{"type":57,"coordinates":58},"Point",[59,60],89.25166,25.74664,{"lat":60,"lon":59},[63,67],{"name":64,"role":44,"phone":65,"phoneExt":30,"email":66},"Towfida Siddiqua, PhD","880-1718-722147","towfida.jivita@gmail.com",{"name":68,"role":44,"phone":30,"phoneExt":30,"email":69},"Hasmot Ali, MBBS, MPH","hasmot.jivita@gmail.com",{"type":71,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR",[73,75],{"name":74,"class":6},"International Centre for Diarrhoeal Disease Research, Bangladesh",{"name":76,"class":6},"Bill and Melinda Gates Foundation","100646025","phase-3-micronutrient-enhancement-for-development-and-health-in-adolescents---the-medha-study-100646025",false,"NCT07695883","Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study","Micronutrient Enhancement for Development and Health in Adolescents","MEDHA","Inclusion Criteria:\n\n* Unmarried 10-18 year old females\n* living in their parental home in the study area\n\nExclusion Criteria:\n\n* Married females under 18 years old;\n* those with a history or diagnosis of chronic or congenital heart disease, chronic kidney or lung disease, cancer, and epilepsy",true,"FEMALE","10 Years","18 Years",{"count":90,"type":91},3000,"ESTIMATED","INTERVENTIONAL",[94],"PHASE3","MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS) formulation and to test an enhanced regimen (MMS+) with additional nutrients, vs. weekly iron-folic acid as standard of care on outcomes of neurodevelopment, linear growth, biochemical status, bone health, and other functional and health outcomes. This study is an individually randomized, open-label, three-arm trial of 3,000 participants supplemented for 12 months to assess the efficacy and safety of nutrient supplementation. Results of the study will inform the design of nutritional interventions and policy for this age group. In the context of the trial, the investigators will also do in-depth clinical and health assessments and collect biospecimens for a bio-archive for future deep-phenotyping of this population. This study will be conducted at the Johns Hopkins Bangladesh JiVitA field site in rural Gaibandha District of Bangladesh.",[97,98,99,100,101,102,103,104,105,106],"Neurodevelopment Outcome","Linear Growth","Micronutrient Status","Bone Mineral Density","Underweight","Stunting","Body Composition","Blood Pressure","HRQOL (Health Related Quality Of Life)","Waist-to-height Ratio","NOT_YET_RECRUITING","2026-08-03",{"date":110,"type":111},"2026-08-06","ACTUAL",{"date":113,"type":91},"2026-09-01",{"date":115,"type":91},"2028-06-30",{"name":5,"class":6},1]