[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522230":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":60,"locations":67,"responsibleParty":83,"collaborators":86,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":101,"sex":102,"minAge":103,"maxAge":31,"enrollmentInfo":104,"targetDuration":31,"studyType":107,"phases":108,"briefSummary":110,"conditions":111,"keywords":113,"overallStatus":69,"whyStopped":31,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},{"fullName":5,"class":6},"George Washington University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"MMS with 30 mg iron","ACTIVE_COMPARATOR","MMS with standard UNIMMAP formulation of 15 micronutrients, including 30 mg of iron",[13],"Dietary Supplement: Multiple Micronutrient Supplements with 30 mg of elemental iron",{"label":15,"type":16,"description":17,"interventionNames":18},"MMS with 45 mg iron","EXPERIMENTAL","MMS with 45 mg of iron plus standard UNIMMAP formulation for other 14 micronutrients",[19],"Dietary Supplement: Multiple Micronutrient Supplements with 45 mg of elemental iron",{"label":21,"type":16,"description":22,"interventionNames":23},"MMS with 60 mg iron","MMS with 60 mg of iron plus standard UNIMMAP formulation for other 14 micronutrients",[24],"Dietary Supplement: Multiple Micronutrient Supplements with 60 mg of elemental iron",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIETARY_SUPPLEMENT","Multiple Micronutrient Supplements with 30 mg of elemental iron","MMS with 30 mg iron is the active comparator group. The standard UNIMMAP MMS formulation includes 30 mg of iron which will be taken orally once daily from the time of randomization until delivery.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Multiple Micronutrient Supplements with 45 mg of elemental iron","MMS with 45 mg iron is an intervention group. MMS with 45 mg of iron plus standard UNIMMAP formulation for other 14 micronutrients will be taken orally once daily from the time of randomization until delivery.",[15],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Multiple Micronutrient Supplements with 60 mg of elemental iron","MMS with 60 mg iron is an intervention group. MMS with 60 mg of iron plus standard UNIMMAP formulation for other 14 micronutrients will be taken orally once daily from the time of randomization until delivery.",[21],[41,45,48,51,54,57],{"name":42,"affiliation":43,"role":44},"Blair Wylie, MD, MPH","Columbia University","PRINCIPAL_INVESTIGATOR",{"name":46,"affiliation":47,"role":44},"Honorati Masanja, PhD","Ifakara Health Institute",{"name":49,"affiliation":50,"role":44},"Alfa Muhihi, MD, MPH","Africa Academy for Public Health",{"name":52,"affiliation":53,"role":44},"Andrea Pembe, MD, MMed, PhD, FCOG","Muhimbili University of Health and Allied Sciences",{"name":55,"affiliation":56,"role":44},"Emily R Smith, ScD, MPH","The Goerge Washington University",{"name":58,"affiliation":59,"role":44},"Christopher R Sudfeld, ScD, ScM","Harvard University",[61,65],{"name":55,"role":62,"phone":63,"phoneExt":31,"email":64},"CONTACT","202-994-3589","emilysmith@gwu.edu",{"name":58,"role":62,"phone":31,"phoneExt":31,"email":66},"csudfeld@hsph.harvard.edu",[68],{"facility":53,"status":69,"city":70,"state":31,"zip":31,"country":71,"countryCode":31,"cosmosGeoPoint":72,"geoPoint":77,"contacts":78},"RECRUITING","Dar es Salaam","Tanzania",{"type":73,"coordinates":74},"Point",[75,76],39.26951,-6.82349,{"lat":76,"lon":75},[79],{"name":80,"role":62,"phone":81,"phoneExt":31,"email":82},"Andrea Pembe, MD","255-754-262-483","bpembe@muhas.ac.tz",{"type":44,"investigatorFullName":84,"investigatorTitle":85,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Emily Smith","Principal Investigator",[87,88,90,91,92],{"name":47,"class":6},{"name":89,"class":6},"Harvard School of Public Health (HSPH)",{"name":53,"class":6},{"name":50,"class":6},{"name":43,"class":6},"100522230","phase-3-multiple-micronutrient-supplementation-for-maternal-anemia-prevention-in-tanzania-100522230",false,"NCT06079918","Multiple Micronutrient Supplementation for Maternal Anemia Prevention in Tanzania","Individually Randomized Trial of Higher-dose Iron (60 mg, 45 mg) Compared to Low-dose Iron (30 mg) in Multiple Micronutrient Supplements in Pregnancy on Moderate and Severe Maternal Anemia","MMS-MAP","Inclusion Criteria:\n\n* Attending first ANC visit at study clinics\n* Pregnant women \\\u003C 20 weeks gestation by last menstrual period (LMP)\n* Aged ≥ 18 years old\n* Intending to stay in Dar es Salaam until 6 weeks post delivery\n* Provides informed consent\n\nExclusion Criteria:\n\n* Severe anemia (defined as hemoglobin \\\u003C 8.5 g\u002FdL per Tanzania standard of care)\n* Sickle cell disease (SS and SC) and hemoglobin C disease (CC) as tested by HemoTypeSC\n* Concurrently enrolled in another nutritional clinical trial\n* Pregnant women with disability or condition which would impair their ability to provide informed consent and complete study procedures.",true,"FEMALE","18 Years",{"count":105,"type":106},6381,"ESTIMATED","INTERVENTIONAL",[109],"PHASE3","This is an individually randomized controlled trial to assess the effect of multiple micronutrient supplements (MMS) containing 60 and 45 mg iron as compared to MMS containing 30 mg of iron (standard UNIMMAP formulation) on maternal moderate or severe anemia. This study will help inform countries like Tanzania that currently use IFA containing 60 mg of iron regarding the dose of iron to use in MMS.",[112],"Pregnancy Related",[114,115,116,117,71],"Pregnancy","Multiple Micronutrient Supplementation","Iron","Anemia","2026-07-13",{"date":120,"type":121},"2026-07-14","ACTUAL",{"date":123,"type":121},"2025-03-03",{"date":125,"type":106},"2027-06",{"name":5,"class":6},1]