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LTD.","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Cumulative gastric ulcer healing rate confirmed by upper gastrointestinal endoscopy through Week 8",null,"Week 8",[14,17,19,21,24,26,28],{"measure":15,"description":11,"timeFrame":16},"Gastric ulcer healing rate confirmed by upper gastrointestinal endoscopy at Week 4","Week 4",{"measure":18,"description":11,"timeFrame":16},"Gastric ulcer healing rate confirmed by upper gastrointestinal endoscopy at Week 4 according to H. pylori infection status.",{"measure":20,"description":11,"timeFrame":12},"Cumulative gastric ulcer healing rate confirmed by upper gastrointestinal endoscopy through Week 8 according to H. pylori infection status.",{"measure":22,"description":11,"timeFrame":23},"Changes in NDI scores at Weeks 4 and 8.","Week 4 and Week 8",{"measure":25,"description":11,"timeFrame":23},"Changes in the number of gastric ulcers at Weeks 4 and 8.",{"measure":27,"description":11,"timeFrame":23},"Change from baseline in gastric ulcer size assessed by upper gastrointestinal endoscopy",{"measure":29,"description":11,"timeFrame":23},"Percentage change from baseline in gastric ulcer size assessed by upper gastrointestinal endoscopy at Week 4 and Week 8",{"allocation":31,"interventionModel":32,"interventionModelDescription":11,"primaryPurpose":33,"observationalModel":11,"timePerspective":11,"maskingInfo":34},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":35,"maskingDescription":36,"whoMasked":37},"DOUBLE","Double-Blind",[38,39],"PARTICIPANT","INVESTIGATOR",[41,46],{"label":42,"type":43,"description":11,"interventionNames":44},"Study Group","EXPERIMENTAL",[45],"Drug: DWP14012 40mg (Fexuprazan)",{"label":47,"type":48,"description":11,"interventionNames":49},"Control Group","ACTIVE_COMPARATOR",[50],"Drug: Lansoprazole 30mg",[52,57],{"type":53,"name":54,"description":55,"armGroupLabels":56,"otherNames":11},"DRUG","DWP14012 40mg (Fexuprazan)","DWP14012 40mg(Fexuprazan) + placebo of Lansoprazole",[42],{"type":53,"name":58,"description":59,"armGroupLabels":60,"otherNames":11},"Lansoprazole 30mg","Lansoprazole 30mg + Placebo of DWP14012 40mg",[47],[62],{"name":63,"role":64,"phone":65,"phoneExt":11,"email":66},"Hokyun Yoo","CONTACT","+82)02-550-8800","2220160@daewoong.co.kr",[68,83],{"facility":69,"status":11,"city":70,"state":11,"zip":11,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":78,"contacts":79},"RS Cipto Mangunkusumo","Jakarta","Indonesia","ID",{"type":74,"coordinates":75},"Point",[76,77],106.84513,-6.21462,{"lat":77,"lon":76},[80],{"name":81,"role":64,"phone":82,"phoneExt":11,"email":66},"Rabbinu Rangga Pribadi","+82)550-8800",{"facility":84,"status":11,"city":85,"state":11,"zip":11,"country":86,"countryCode":11,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"The Catholic University of Korea, Incheon St. Mary'S Hospital","Incheon","South Korea",{"type":74,"coordinates":88},[89,90],126.70515,37.45646,{"lat":90,"lon":89},[93],{"name":94,"role":64,"phone":82,"phoneExt":11,"email":66},"Kim Byung-Wook",{"type":96,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100649123","phase-3-phase-3-to-evaluate-the-efficacy-and-safety-of-dwp14012-in-patients-with-gastric-ulcer-100649123",false,"NCT07730138","Phase 3 to Evaluate the Efficacy and Safety of DWP14012 in Patients With Gastric Ulcer","A Multinational, Multicenter, Randomized, Double-blind, Active-controlled, Parallel-group, Phase 3 Study to Evaluate the Efficacy and Safety of DWP14012 in Participants With Gastric Ulcer","Inclusion Criteria:\n\n1. At least one gastric ulcer is present, and the largest gastric ulcer measures ≥ 3 mm and ≤ 30 mm in diameter\n2. The Sakita-Miwa classification of the largest gastric ulcer is A1 or A2.\n\nExclusion Criteria:\n\n1. Participants with a history of Zollinger-Ellison syndrome or conditions associated with gastric hypersecretion.\n2. Participants who, within 30 days prior to the screening visit (Visit 1), have undergone or are scheduled to undergo major surgery that may affect gastric acid secretion.\n3. Participants with a history of malignancy within 5 years prior to the screening visit (Visit 1); gastrointestinal malignancies are excluded regardless of the time elapsed.\n4. Participants who, at the screening visit (Visit 1), have gastrointestinal active bleeding , esophageal stricture, ulcer-induced stenosis, pyloric stenosis, gastroesophageal varices, Barrett's esophagus (\\> 3 cm), esophageal dysplasia, duodenal ulcer, refractory ulcer, perforated ulcer, or surgery-induced ulcer\n5. Participants who, at the screening visit (Visit 1), have pancreatitis or inflammatory bowel disease (including Crohn's disease, ulcerative colitis, or intestinal Behçet's disease).","ALL","19 Years",{"count":107,"type":108},384,"ESTIMATED","INTERVENTIONAL",[111],"PHASE3","A Multinational, Multicenter, Randomized, Double-blind, Active-controlled, Parallel-group, Phase 3 Study to Evaluate the Efficacy and Safety of DWP14012 in Participants with Gastric Ulcer",[114],"Gastric Ulcer",[116,114,117,118,119,120],"DWP14012","P-CAB","peptic ulcer","stomach ulcer","duodenal ulcer","NOT_YET_RECRUITING","2026-07-22",{"date":124,"type":125},"2026-07-28","ACTUAL",{"date":127,"type":108},"2026-10-15",{"date":129,"type":108},"2028-10-15",{"name":5,"class":6},2]