[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603722":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":23,"locations":29,"responsibleParty":136,"collaborators":11,"id":139,"slug":140,"hasResults":141,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":145,"eligibilityCriteria":146,"healthyVolunteers":141,"sex":147,"minAge":148,"maxAge":11,"enrollmentInfo":149,"targetDuration":11,"studyType":152,"phases":153,"briefSummary":155,"conditions":156,"keywords":11,"overallStatus":32,"whyStopped":11,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":168},{"fullName":5,"class":6},"University Hospital, Geneva","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Low-molecular-weight heparin","EXPERIMENTAL",null,[13],"Drug: Low-dose low-molecular-weight heparin",{"label":15,"type":16,"description":11,"interventionNames":11},"No treatment","NO_INTERVENTION",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"DRUG","Low-dose low-molecular-weight heparin","Low-molecular-weight heparin given for 7-10 days after delivery:\n\n* enoxaparin 4000-6000IU o.d.\n* nadroparin 3800-5700IU o.d.\n* dalteparin 5000-7500IU o.d.\n* tinzaparin 4500-7000IU o.d.",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Marc Blondon","CONTACT","(+41).22.372.92.92","marc.blondon@hug.ch",[30,47,60,73,84,97,110,123],{"facility":31,"status":32,"city":33,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Kantonsspital Baden","RECRUITING","Baden","Switzerland","CH",{"type":37,"coordinates":38},"Point",[39,40],8.30592,47.47333,{"lat":40,"lon":39},[43],{"name":44,"role":26,"phone":45,"phoneExt":11,"email":46},"Prof. Leonhard Schäffer","0041.56.486.3599","geburtshilfe@ksb.ch",{"facility":48,"status":32,"city":49,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":50,"geoPoint":54,"contacts":55},"Universitätsspital Basel","Basel",{"type":37,"coordinates":51},[52,53],7.57327,47.55839,{"lat":53,"lon":52},[56],{"name":57,"role":26,"phone":58,"phoneExt":11,"email":59},"Prof. Beatrice Mosimann","0041.61.265.96.90","studienhebamme@usb.ch",{"facility":61,"status":32,"city":62,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Lindenhofspital","Bern",{"type":37,"coordinates":64},[65,66],7.44744,46.94809,{"lat":66,"lon":65},[69],{"name":70,"role":26,"phone":71,"phoneExt":11,"email":72},"Prof. Martin Müller","0041.31.300.85.80","martin.mueller@lindehofgruppe.ch",{"facility":74,"status":32,"city":75,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Geneva University Hospitals","Geneva",{"type":37,"coordinates":77},[78,79],6.14569,46.20222,{"lat":79,"lon":78},[82],{"name":25,"role":26,"phone":83,"phoneExt":11,"email":28},"0041 223729292",{"facility":85,"status":32,"city":86,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Centre Hospitalier Universitaire Vaudois","Lausanne",{"type":37,"coordinates":88},[89,90],6.63282,46.516,{"lat":90,"lon":89},[93],{"name":94,"role":26,"phone":95,"phoneExt":11,"email":96},"Prof. David Baud","0041.21.314.74.81","david.baud@chuv.ch",{"facility":98,"status":32,"city":99,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Ente Ospedaliero Cantonale","Lugano",{"type":37,"coordinates":101},[102,103],8.96004,46.01008,{"lat":103,"lon":102},[106],{"name":107,"role":26,"phone":108,"phoneExt":11,"email":109},"Prof. Andrea Papadia","0041.91.811.96.57","mariacarla.andreozzi@eoc.ch",{"facility":111,"status":32,"city":112,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":113,"geoPoint":117,"contacts":118},"Réseau Hospitalier Neuchâtelois","Neuchâtel",{"type":37,"coordinates":114},[115,116],6.931,46.99179,{"lat":116,"lon":115},[119],{"name":120,"role":26,"phone":121,"phoneExt":11,"email":122},"Dre Romina Capoccia-Brugger","0041.32.713.36.53","romina.capoccia-brugger@rhne.ch",{"facility":124,"status":32,"city":125,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"Hôpital du Valais","Sion",{"type":37,"coordinates":127},[128,129],7.35559,46.22739,{"lat":129,"lon":128},[132],{"name":133,"role":26,"phone":134,"phoneExt":11,"email":135},"Prof. Daniela Huber","0041.27.603.87.87","danielaemanuela.huber@hopitalvs.ch",{"type":137,"investigatorFullName":25,"investigatorTitle":138,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Principal Investigator","100603722","phase-3-short-term-low-dose-low-molecular-weight-heparin-to-prevent-postpartum-thrombosis-100603722",false,"NCT07140211","Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis","Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis: a Pragmatic, Multi-center, Open-label Randomized Controlled Study","SHINE","Inclusion Criteria: postpartum women after delivery AND ≥1 major risk factor \u002F ≥2 minor risk factors:\n\n* Major risk factors: Emergency cesarean section ; Pre-pregnancy BMI ≥35kg\u002Fm2 ; Known low-risk thrombophilia (heterozygous factor V Leiden; heterozygous G20210 prothrombin mutation) ; Pre-eclampsia ; Pre-term delivery ; Peripartum systemic infection ; Intra-uterine growth restriction ; Pregnancy loss\n* Minor risk factors: Age ≥35 years ; Pre-pregnancy BMI 30.0-34.9kg\u002Fm2 ; Current smoking ; Elective cesarean section ; Postpartum hemorrhage ; Antenatal immobility\n\nExclusion Criteria:\n\n* ≥2 doses of postpartum LMWH\n* Any indication for therapeutic anticoagulation\n* A high-risk of postpartum VTE\n* An increased bleeding risk\n* A contra-indication to heparin","FEMALE","18 Years",{"count":150,"type":151},9200,"ESTIMATED","INTERVENTIONAL",[154],"PHASE3","The goal of this clinical trial is to evaluate the risk-benefit of a short-term treatment with a low-dose low-molecular-weight heparin (LMWH), in the postpartum period (after delivery). The main questions it aims to answer are:\n\n* compared to no treatment, does short-term postpartum LMWH modify the risk of venous thromboembolism within 90 days of delivery?\n* compared to no treatment, does short-term postpartum LMWH modify the risks of bleeding and wound complications? Participants will take low-dose LMWH for 7-10 days or no treatment, and will be followed for 90 days post-delivery.",[157,158],"Venous Thromboembolism (VTE)","Postpartum","2026-07-23",{"date":161,"type":162},"2026-07-24","ACTUAL",{"date":164,"type":162},"2025-10-15",{"date":166,"type":151},"2030-08",{"name":25,"class":6},8]