[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612334":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":24,"locations":30,"responsibleParty":773,"collaborators":18,"id":775,"slug":776,"hasResults":777,"nctId":778,"briefTitle":779,"officialTitle":780,"acronym":781,"eligibilityCriteria":782,"healthyVolunteers":777,"sex":783,"minAge":784,"maxAge":18,"enrollmentInfo":785,"targetDuration":18,"studyType":788,"phases":789,"briefSummary":791,"conditions":792,"keywords":798,"overallStatus":33,"whyStopped":18,"lastUpdateSubmitDate":809,"lastUpdatePostDateStruct":810,"startDateStruct":813,"completionDateStruct":815,"leadSponsor":817,"locationsCount":818},{"fullName":5,"class":6},"Revolution Medicines, Inc.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"daraxonrasib","EXPERIMENTAL","study drug",[13],"Drug: daraxonrasib",{"label":15,"type":16,"description":17,"interventionNames":18},"SOC Observation","NO_INTERVENTION","Patients randomized to the comparator control arm will receive SOC observation.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"DRUG","oral tablets",[9],[25],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Revolution Medicines Study Director","CONTACT","1-844-2-REVMED","medinfo@revmed.com",[31,50,65,79,91,105,119,129,144,158,172,185,200,215,225,243,253,262,277,292,302,317,333,342,353,363,378,393,403,413,428,441,456,466,478,488,495,511,522,528,537,546,555,571,585,594,607,623,638,652,663,674,690,696,705,714,730,739,753,764],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Mayo Clinic","RECRUITING","Phoenix","Arizona","85054","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-112.07404,33.44838,{"lat":43,"lon":42},[46],{"name":47,"role":27,"phone":48,"phoneExt":18,"email":49},"Tanios Bekaii-Saab","480-342-4800","bekaii-saab.tanios@mayo.edu",{"facility":51,"status":33,"city":52,"state":53,"zip":54,"country":37,"countryCode":38,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"UC San Diego Moores Cancer Center","La Jolla","California","92037",{"type":40,"coordinates":56},[57,58],-117.2742,32.84727,{"lat":58,"lon":57},[61],{"name":62,"role":27,"phone":63,"phoneExt":18,"email":64},"Shakeela Dad","858-822-5376","sdad@health.ucsd.edu",{"facility":66,"status":33,"city":67,"state":53,"zip":68,"country":37,"countryCode":38,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Cedars-Sinai Cancer at Cedars-Sinai Medical Center","Los Angeles","90048",{"type":40,"coordinates":70},[71,72],-118.24368,34.05223,{"lat":72,"lon":71},[75],{"name":76,"role":27,"phone":77,"phoneExt":18,"email":78},"Naomi Geier","310-423-4693","naomi.geier@cshs.org",{"facility":80,"status":33,"city":67,"state":53,"zip":81,"country":37,"countryCode":38,"cosmosGeoPoint":82,"geoPoint":84,"contacts":85},"University of California, Los Angeles","90404",{"type":40,"coordinates":83},[71,72],{"lat":72,"lon":71},[86],{"name":87,"role":27,"phone":88,"phoneExt":89,"email":90},"Madeleine Manahan","310-633-8400","x19212","mmanahan@mednet.ucla.edu",{"facility":92,"status":33,"city":93,"state":53,"zip":94,"country":37,"countryCode":38,"cosmosGeoPoint":95,"geoPoint":99,"contacts":100},"Stanford Cancer Institute","Palo Alto","94304",{"type":40,"coordinates":96},[97,98],-122.14302,37.44188,{"lat":98,"lon":97},[101],{"name":102,"role":27,"phone":103,"phoneExt":18,"email":104},"Cassandra Blake","650-725-9895","cblake1@stanford.edu",{"facility":106,"status":33,"city":107,"state":53,"zip":108,"country":37,"countryCode":38,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"University of California, San Francisco","San Francisco","94143",{"type":40,"coordinates":110},[111,112],-122.41942,37.77493,{"lat":112,"lon":111},[115],{"name":116,"role":27,"phone":117,"phoneExt":18,"email":118},"Kevin Lopez","415-502-3310","Kevin.lopez@ucsf.edu",{"facility":120,"status":33,"city":121,"state":122,"zip":123,"country":37,"countryCode":38,"cosmosGeoPoint":124,"geoPoint":128,"contacts":18},"Rocky Mountain Cancer Centers, LLP","Lakewood","Colorado","80228",{"type":40,"coordinates":125},[126,127],-105.08137,39.70471,{"lat":127,"lon":126},{"facility":130,"status":33,"city":131,"state":132,"zip":133,"country":37,"countryCode":38,"cosmosGeoPoint":134,"geoPoint":138,"contacts":139},"Hartford Healthcare","Hartford","Connecticut","06103",{"type":40,"coordinates":135},[136,137],-72.68509,41.76371,{"lat":137,"lon":136},[140],{"name":141,"role":27,"phone":142,"phoneExt":18,"email":143},"Jonathan Steinmetz","860-972-4183","jonathan.steinmetz@hhchealth.org",{"facility":32,"status":33,"city":145,"state":146,"zip":147,"country":37,"countryCode":38,"cosmosGeoPoint":148,"geoPoint":152,"contacts":153},"Jacksonville","Florida","32224",{"type":40,"coordinates":149},[150,151],-81.65565,30.33218,{"lat":151,"lon":150},[154],{"name":155,"role":27,"phone":156,"phoneExt":18,"email":157},"Hani Babiker","520-626-7866","babiker.hani@mayo.edu",{"facility":159,"status":33,"city":160,"state":146,"zip":161,"country":37,"countryCode":38,"cosmosGeoPoint":162,"geoPoint":166,"contacts":167},"University of Miami Hospital and Clinics, Sylvester Comprehensive Cancer Center","Miami","33136",{"type":40,"coordinates":163},[164,165],-80.19366,25.77427,{"lat":165,"lon":164},[168],{"name":169,"role":27,"phone":170,"phoneExt":18,"email":171},"Yolanda Justal","305-243-2647","yxj512@med.miami.edu",{"facility":173,"status":33,"city":174,"state":146,"zip":175,"country":37,"countryCode":38,"cosmosGeoPoint":176,"geoPoint":180,"contacts":181},"Florida Cancer Specialists","St. Petersburg","33701",{"type":40,"coordinates":177},[178,179],-82.67927,27.77086,{"lat":179,"lon":178},[182],{"name":183,"role":27,"phone":184,"phoneExt":18,"email":18},"Study Coordinator","727-216-1143",{"facility":186,"status":33,"city":187,"state":188,"zip":189,"country":37,"countryCode":38,"cosmosGeoPoint":190,"geoPoint":194,"contacts":195},"Winship Cancer Institute, Emory University","Atlanta","Georgia","30322",{"type":40,"coordinates":191},[192,193],-84.38798,33.749,{"lat":193,"lon":192},[196],{"name":197,"role":27,"phone":198,"phoneExt":18,"email":199},"Kathleen Coleman","404-251-1278","kathleen.marie.coleman@emory.edu",{"facility":201,"status":33,"city":202,"state":203,"zip":204,"country":37,"countryCode":38,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"Community Health Network","Indianapolis","Indiana","46250",{"type":40,"coordinates":206},[207,208],-86.15804,39.76838,{"lat":208,"lon":207},[211],{"name":212,"role":27,"phone":213,"phoneExt":18,"email":214},"Adam Norris","317-621-3858","anorris@ecommunity.com",{"facility":216,"status":33,"city":217,"state":218,"zip":219,"country":37,"countryCode":38,"cosmosGeoPoint":220,"geoPoint":224,"contacts":18},"University of Kansas Medical Center Research Institute, Inc.","Lawrence","Kansas","66045",{"type":40,"coordinates":221},[222,223],-95.23525,38.97167,{"lat":223,"lon":222},{"facility":226,"status":33,"city":227,"state":228,"zip":229,"country":37,"countryCode":38,"cosmosGeoPoint":230,"geoPoint":234,"contacts":235},"Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins & Sibley Memorial Hospital","Baltimore","Maryland","21287",{"type":40,"coordinates":231},[232,233],-76.61219,39.29038,{"lat":233,"lon":232},[236,240],{"name":237,"role":27,"phone":238,"phoneExt":18,"email":239},"GI Clinical Trial Referrals","410-614-3644","giclinicaltrials@jhmi.edu",{"name":241,"role":27,"phone":242,"phoneExt":18,"email":18},"Mike Pishvaian","202-660-6500",{"facility":244,"status":33,"city":245,"state":246,"zip":247,"country":37,"countryCode":38,"cosmosGeoPoint":248,"geoPoint":252,"contacts":18},"Massachusetts General Hospital","Boston","Massachusetts","02114",{"type":40,"coordinates":249},[250,251],-71.05977,42.35843,{"lat":251,"lon":250},{"facility":254,"status":33,"city":245,"state":246,"zip":255,"country":37,"countryCode":38,"cosmosGeoPoint":256,"geoPoint":258,"contacts":259},"Dana Farber Cancer Institute (DFCI)","02215",{"type":40,"coordinates":257},[250,251],{"lat":251,"lon":250},[260],{"name":18,"role":27,"phone":261,"phoneExt":18,"email":18},"617-632-3000",{"facility":263,"status":33,"city":264,"state":265,"zip":266,"country":37,"countryCode":38,"cosmosGeoPoint":267,"geoPoint":271,"contacts":272},"Mayo Clinic Cancer Center","Rochester","Minnesota","55905",{"type":40,"coordinates":268},[269,270],-92.4699,44.02163,{"lat":270,"lon":269},[273],{"name":274,"role":27,"phone":275,"phoneExt":18,"email":276},"Ryan Carr","507-284-2511","carr.ryan@mayo.edu",{"facility":278,"status":33,"city":279,"state":280,"zip":281,"country":37,"countryCode":38,"cosmosGeoPoint":282,"geoPoint":286,"contacts":287},"Saint Luke's Cancer Institute","Kansas City","Missouri","64111",{"type":40,"coordinates":283},[284,285],-94.57857,39.09973,{"lat":285,"lon":284},[288],{"name":289,"role":27,"phone":290,"phoneExt":18,"email":291},"Marc Roth","816-932-2677","mroth@saint-lukes.org",{"facility":293,"status":33,"city":294,"state":295,"zip":296,"country":37,"countryCode":38,"cosmosGeoPoint":297,"geoPoint":301,"contacts":18},"University of Nebraska Medical Center","Omaha","Nebraska","68198",{"type":40,"coordinates":298},[299,300],-95.94043,41.25626,{"lat":300,"lon":299},{"facility":303,"status":33,"city":304,"state":305,"zip":306,"country":37,"countryCode":38,"cosmosGeoPoint":307,"geoPoint":311,"contacts":312},"Comprehensive Cancer Centers of Nevada","Las Vegas","Nevada","89169",{"type":40,"coordinates":308},[309,310],-115.13722,36.17497,{"lat":310,"lon":309},[313],{"name":314,"role":27,"phone":315,"phoneExt":18,"email":316},"Ann Lovelace","702-609-9460","ann.lovelace@usoncology.com",{"facility":318,"status":33,"city":319,"state":319,"zip":320,"country":37,"countryCode":38,"cosmosGeoPoint":321,"geoPoint":325,"contacts":326},"Laura and Issac Perlmutter Cancer Center at NYU Langone-Ambulatory Care Center","New York","10016",{"type":40,"coordinates":322},[323,324],-74.00597,40.71427,{"lat":324,"lon":323},[327,331],{"name":328,"role":27,"phone":329,"phoneExt":18,"email":330},"Mark Bond","212-731-6120","Ct.gov@nyulangone.org",{"name":332,"role":27,"phone":329,"phoneExt":18,"email":330},"Jennifer Coffey",{"facility":334,"status":33,"city":319,"state":319,"zip":335,"country":37,"countryCode":38,"cosmosGeoPoint":336,"geoPoint":338,"contacts":339},"Columbia University Medical Center","10032",{"type":40,"coordinates":337},[323,324],{"lat":324,"lon":323},[340],{"name":18,"role":27,"phone":18,"phoneExt":18,"email":341},"cancerclinicaltrials@cumc.columbia.edu",{"facility":343,"status":33,"city":319,"state":319,"zip":344,"country":37,"countryCode":38,"cosmosGeoPoint":345,"geoPoint":347,"contacts":348},"Memorial Sloan Kettering Cancer Center","10065",{"type":40,"coordinates":346},[323,324],{"lat":324,"lon":323},[349],{"name":350,"role":27,"phone":351,"phoneExt":18,"email":352},"Eileen O'Reilly","646-888-4182","oreillye@MSKCC.ORG",{"facility":354,"status":33,"city":355,"state":356,"zip":357,"country":37,"countryCode":38,"cosmosGeoPoint":358,"geoPoint":362,"contacts":18},"Duke Cancer Center","Durham","North Carolina","27710",{"type":40,"coordinates":359},[360,361],-78.89862,35.99403,{"lat":361,"lon":360},{"facility":364,"status":33,"city":365,"state":366,"zip":367,"country":37,"countryCode":38,"cosmosGeoPoint":368,"geoPoint":372,"contacts":373},"Taylor Cancer Research Center","Maumee","Ohio","43537",{"type":40,"coordinates":369},[370,371],-83.65382,41.56283,{"lat":371,"lon":370},[374],{"name":375,"role":27,"phone":376,"phoneExt":18,"email":377},"Stephanie Ambrose","567-402-4502","sambrose@tcrcpt.org",{"facility":379,"status":33,"city":380,"state":381,"zip":382,"country":37,"countryCode":38,"cosmosGeoPoint":383,"geoPoint":387,"contacts":388},"Avera Cancer Institute","Sioux Falls","South Dakota","57105",{"type":40,"coordinates":384},[385,386],-96.72796,43.54369,{"lat":386,"lon":385},[389],{"name":390,"role":27,"phone":391,"phoneExt":18,"email":392},"Heidi McKean","605-322-6900","heidi.mckean@avera.org",{"facility":394,"status":33,"city":395,"state":396,"zip":397,"country":37,"countryCode":38,"cosmosGeoPoint":398,"geoPoint":402,"contacts":18},"SCRI Oncology Partners","Nashville","Tennessee","37203",{"type":40,"coordinates":399},[400,401],-86.78444,36.16589,{"lat":401,"lon":400},{"facility":404,"status":33,"city":405,"state":406,"zip":407,"country":37,"countryCode":38,"cosmosGeoPoint":408,"geoPoint":412,"contacts":18},"Texas Oncology - DFW","Dallas","Texas","75246",{"type":40,"coordinates":409},[410,411],-96.80667,32.78306,{"lat":411,"lon":410},{"facility":414,"status":415,"city":416,"state":406,"zip":417,"country":37,"countryCode":38,"cosmosGeoPoint":418,"geoPoint":422,"contacts":423},"University of Texas MD Anderson Cancer Center","NOT_YET_RECRUITING","Houston","77030",{"type":40,"coordinates":419},[420,421],-95.36327,29.76328,{"lat":421,"lon":420},[424],{"name":425,"role":27,"phone":426,"phoneExt":18,"email":427},"Kim Ross","713-794-1623","GIClinicalTrials@mdanderson.org",{"facility":429,"status":33,"city":430,"state":406,"zip":431,"country":37,"countryCode":38,"cosmosGeoPoint":432,"geoPoint":436,"contacts":437},"Texas Oncology - Northeast Texas","Longview","75601",{"type":40,"coordinates":433},[434,435],-94.74049,32.5007,{"lat":435,"lon":434},[438],{"name":439,"role":27,"phone":18,"phoneExt":18,"email":440},"Angie Smith","Angie.smith2@usoncology.com",{"facility":442,"status":33,"city":443,"state":444,"zip":445,"country":37,"countryCode":38,"cosmosGeoPoint":446,"geoPoint":450,"contacts":451},"University of Utah, Huntsman Cancer Institute","Salt Lake City","Utah","94112",{"type":40,"coordinates":447},[448,449],-111.89105,40.76078,{"lat":449,"lon":448},[452],{"name":453,"role":27,"phone":454,"phoneExt":18,"email":455},"Susan Sherry","801-585-3453","susan.sharry@hci.utah.edu",{"facility":457,"status":33,"city":458,"state":459,"zip":460,"country":37,"countryCode":38,"cosmosGeoPoint":461,"geoPoint":465,"contacts":18},"Virginia Cancer Specialists","Fairfax","Virginia","22031",{"type":40,"coordinates":462},[463,464],-77.30637,38.84622,{"lat":464,"lon":463},{"facility":467,"status":33,"city":468,"state":469,"zip":470,"country":471,"countryCode":472,"cosmosGeoPoint":473,"geoPoint":477,"contacts":18},"CRLCC Eugene Marquis","Rennes","Cedex","35042","France","FR",{"type":40,"coordinates":474},[475,476],-1.67431,48.11109,{"lat":476,"lon":475},{"facility":479,"status":33,"city":480,"state":481,"zip":482,"country":471,"countryCode":472,"cosmosGeoPoint":483,"geoPoint":487,"contacts":18},"Hôpital Paul Brousse","Villejuif","Val-De- Marne","94804",{"type":40,"coordinates":484},[485,486],2.35992,48.7939,{"lat":486,"lon":485},{"facility":489,"status":33,"city":480,"state":490,"zip":491,"country":471,"countryCode":472,"cosmosGeoPoint":492,"geoPoint":494,"contacts":18},"Institut Gustave Roussy","Val-de-Marne","94805",{"type":40,"coordinates":493},[485,486],{"lat":486,"lon":485},{"facility":496,"status":33,"city":497,"state":18,"zip":498,"country":499,"countryCode":500,"cosmosGeoPoint":501,"geoPoint":505,"contacts":506},"Universitaetsklinikum Heidelberg","Heidelberg","69120","Germany","DE",{"type":40,"coordinates":502},[503,504],8.69079,49.40768,{"lat":504,"lon":503},[507],{"name":508,"role":27,"phone":509,"phoneExt":18,"email":510},"Christoph Springfeld","+49 6221 56 6857","christoph.springfeld@med.uni-heidelberg.de",{"facility":512,"status":33,"city":513,"state":18,"zip":514,"country":515,"countryCode":516,"cosmosGeoPoint":517,"geoPoint":521,"contacts":18},"Fondazione IRCCS Istituto Nazionale dei Tumori","Milan","20133","Italy","IT",{"type":40,"coordinates":518},[519,520],12.59836,42.78235,{"lat":520,"lon":519},{"facility":523,"status":33,"city":513,"state":18,"zip":524,"country":515,"countryCode":516,"cosmosGeoPoint":525,"geoPoint":527,"contacts":18},"IEO - Instituto Europeo di Oncologia","20141",{"type":40,"coordinates":526},[519,520],{"lat":520,"lon":519},{"facility":529,"status":33,"city":530,"state":18,"zip":531,"country":515,"countryCode":516,"cosmosGeoPoint":532,"geoPoint":536,"contacts":18},"IOV - Istituto Oncologico Veneto IRCCS","Padova","35128",{"type":40,"coordinates":533},[534,535],11.14261,44.38225,{"lat":535,"lon":534},{"facility":538,"status":33,"city":539,"state":18,"zip":540,"country":515,"countryCode":516,"cosmosGeoPoint":541,"geoPoint":545,"contacts":18},"Azienda Ospedaliero Universitaria Pisana","Pisa","56126",{"type":40,"coordinates":542},[543,544],10.4036,43.70853,{"lat":544,"lon":543},{"facility":547,"status":33,"city":548,"state":18,"zip":549,"country":515,"countryCode":516,"cosmosGeoPoint":550,"geoPoint":554,"contacts":18},"Centro Ricerche Cliniche di Verona s.r.l.","Verona","37134",{"type":40,"coordinates":551},[552,553],10.9938,45.43854,{"lat":553,"lon":552},{"facility":556,"status":33,"city":557,"state":558,"zip":559,"country":560,"countryCode":561,"cosmosGeoPoint":562,"geoPoint":566,"contacts":567},"Kanagawa Cancer Center","Yokohama","Kanagawa","241-8515","Japan","JP",{"type":40,"coordinates":563},[564,565],139.65,35.43333,{"lat":565,"lon":564},[568],{"name":569,"role":27,"phone":18,"phoneExt":18,"email":570},"Makoto Ueno","kccmakoto23u@gmail.com",{"facility":572,"status":33,"city":573,"state":18,"zip":574,"country":560,"countryCode":561,"cosmosGeoPoint":575,"geoPoint":579,"contacts":580},"National Cancer Center Hospital East","Chiba","277-8577",{"type":40,"coordinates":576},[577,578],140.11667,35.6,{"lat":578,"lon":577},[581],{"name":582,"role":27,"phone":583,"phoneExt":18,"email":584},"Masafumi Ikeda","81471331111","masikeda@east.ncc.go.jp",{"facility":586,"status":33,"city":587,"state":18,"zip":588,"country":560,"countryCode":561,"cosmosGeoPoint":589,"geoPoint":593,"contacts":18},"Kyoto University Hospital","Kyoto","606-8507",{"type":40,"coordinates":590},[591,592],135.75385,35.02107,{"lat":592,"lon":591},{"facility":595,"status":33,"city":596,"state":18,"zip":597,"country":560,"countryCode":561,"cosmosGeoPoint":598,"geoPoint":602,"contacts":603},"Cancer Institute Hospital of JFCR","Tokyo","135-8550",{"type":40,"coordinates":599},[600,601],139.69171,35.6895,{"lat":601,"lon":600},[604],{"name":605,"role":27,"phone":18,"phoneExt":18,"email":606},"Masato Ozaka","masato.ozaka@jfcr.or.jp",{"facility":608,"status":33,"city":609,"state":18,"zip":610,"country":611,"countryCode":612,"cosmosGeoPoint":613,"geoPoint":617,"contacts":618},"Pan American Oncology Trials, LLC","San Juan","00909","Puerto Rico","PR",{"type":40,"coordinates":614},[615,616],-66.10572,18.46633,{"lat":616,"lon":615},[619],{"name":620,"role":27,"phone":621,"phoneExt":18,"email":622},"Principal Investigator","787-407-3333","info@panoncologytrials.com",{"facility":624,"status":33,"city":625,"state":18,"zip":626,"country":627,"countryCode":18,"cosmosGeoPoint":628,"geoPoint":632,"contacts":633},"Dong-A University Hospital","Busan","49201","South Korea",{"type":40,"coordinates":629},[630,631],129.03004,35.10168,{"lat":631,"lon":630},[634],{"name":635,"role":27,"phone":636,"phoneExt":18,"email":637},"Ae ri Jang","82512402576","dongahicrc33@naver.com",{"facility":639,"status":33,"city":640,"state":18,"zip":641,"country":627,"countryCode":18,"cosmosGeoPoint":642,"geoPoint":646,"contacts":647},"Seoul National University Hospital","Seoul","03080",{"type":40,"coordinates":643},[644,645],126.9784,37.566,{"lat":645,"lon":644},[648],{"name":649,"role":27,"phone":650,"phoneExt":18,"email":651},"Do-Yoon Oh","82220720701","ohdoyoun@snu.ac.kr",{"facility":653,"status":33,"city":640,"state":18,"zip":654,"country":627,"countryCode":18,"cosmosGeoPoint":655,"geoPoint":657,"contacts":658},"Asan Medical Center","05505",{"type":40,"coordinates":656},[644,645],{"lat":645,"lon":644},[659],{"name":660,"role":27,"phone":661,"phoneExt":18,"email":662},"Changhoon Yoo","82230101727","yooc@amc.seoul.kr",{"facility":664,"status":33,"city":640,"state":18,"zip":665,"country":627,"countryCode":18,"cosmosGeoPoint":666,"geoPoint":668,"contacts":669},"Samsung Medical Center","06351",{"type":40,"coordinates":667},[644,645],{"lat":645,"lon":644},[670],{"name":671,"role":27,"phone":672,"phoneExt":18,"email":673},"Joon Oh Park","821099333457","oncopark@skku.edu",{"facility":675,"status":33,"city":676,"state":18,"zip":677,"country":678,"countryCode":679,"cosmosGeoPoint":680,"geoPoint":684,"contacts":685},"Hospital Universitari Vall d'Hebron - VHIO","Barcelona","08035","Spain","ES",{"type":40,"coordinates":681},[682,683],2.15899,41.38879,{"lat":683,"lon":682},[686],{"name":687,"role":27,"phone":688,"phoneExt":18,"email":689},"Jordi Perera","0034 932543454 ext. 1256","jperera@vhio.net",{"facility":691,"status":33,"city":676,"state":18,"zip":692,"country":678,"countryCode":679,"cosmosGeoPoint":693,"geoPoint":695,"contacts":18},"Hospital Clinic de Barcelona","08036",{"type":40,"coordinates":694},[682,683],{"lat":683,"lon":682},{"facility":697,"status":33,"city":698,"state":18,"zip":699,"country":678,"countryCode":679,"cosmosGeoPoint":700,"geoPoint":704,"contacts":18},"Hospital Universitario 12 de Octubre","Madrid","28041",{"type":40,"coordinates":701},[702,703],-3.70256,40.4165,{"lat":703,"lon":702},{"facility":706,"status":33,"city":707,"state":18,"zip":708,"country":678,"countryCode":679,"cosmosGeoPoint":709,"geoPoint":713,"contacts":18},"Hospital Universitario Virgen del Rocio","Seville","41013",{"type":40,"coordinates":710},[711,712],-5.97317,37.38283,{"lat":712,"lon":711},{"facility":715,"status":33,"city":716,"state":18,"zip":717,"country":718,"countryCode":719,"cosmosGeoPoint":720,"geoPoint":724,"contacts":725},"University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Medical Centre","Birmingham","B15 2TH","United Kingdom","UK",{"type":40,"coordinates":721},[722,723],-1.89983,52.48142,{"lat":723,"lon":722},[726],{"name":727,"role":27,"phone":728,"phoneExt":18,"email":729},"Shivan Shivakumar","0121 371 3571","Shivan.Sivakumar@uhb.nhs.uk",{"facility":731,"status":33,"city":732,"state":18,"zip":733,"country":718,"countryCode":719,"cosmosGeoPoint":734,"geoPoint":738,"contacts":18},"Beatson West of Scotland Cancer Centre","Glasgow","G22 0YN",{"type":40,"coordinates":735},[736,737],-4.25763,55.86515,{"lat":737,"lon":736},{"facility":740,"status":33,"city":741,"state":18,"zip":742,"country":718,"countryCode":719,"cosmosGeoPoint":743,"geoPoint":747,"contacts":748},"The Royal Marsden NHS Foundation Trust, Royal Marsden Hospital-London","London","SW3 6JJ",{"type":40,"coordinates":744},[745,746],-0.12574,51.50853,{"lat":746,"lon":745},[749],{"name":750,"role":27,"phone":751,"phoneExt":18,"email":752},"Naureen Starling","02078118460","gitrials@rmh.nhs.uk",{"facility":754,"status":33,"city":741,"state":18,"zip":755,"country":718,"countryCode":719,"cosmosGeoPoint":756,"geoPoint":758,"contacts":759},"Imperial College Healthcare NHS Foundation Trust, Hammersmith Hospital","W12 0HS",{"type":40,"coordinates":757},[745,746],{"lat":746,"lon":745},[760],{"name":761,"role":27,"phone":762,"phoneExt":18,"email":763},"Michela Cicchetti","0203 313 8364","michela.cicchetti@nhs.ne",{"facility":765,"status":33,"city":766,"state":18,"zip":767,"country":718,"countryCode":719,"cosmosGeoPoint":768,"geoPoint":772,"contacts":18},"The Christie NHS Foundation Trust","Manchester","M20 4BX",{"type":40,"coordinates":769},[770,771],-2.23743,53.48095,{"lat":771,"lon":770},{"type":774,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100612334","phase-3-study-of-daraxonrasib-rmc-6236-in-patients-with-resected-pancreatic-ductal-adenocarcinoma-pdac-100612334",false,"NCT07252232","Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)","RASolute 304: A Phase 3 Multicenter, Open-label, Randomized, 2-Arm Study of Adjuvant Daraxonrasib Versus Standard of Care Observation Following Completion of Neoadjuvant and\u002For Adjuvant Chemotherapy in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)","RASolute 304","Inclusion Criteria:\n\n* At least 18 years old and has provided informed consent.\n* Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.\n* Histologically confirmed PDAC with successful (R0\u002FR1) curative intent surgical resection and no evidence of recurrent or metastatic disease.\n* Must have received perioperative (neoadjuvant, adjuvant, or a combination of both) multi-agent chemotherapy.\n* Must have completed most recent treatment within the past 12 weeks.\n* Adequate organ function (bone marrow, liver, kidney, coagulation).\n* Documented RAS mutation status.\n* Able to take oral medications.\n\nExclusion Criteria:\n\n* Prior therapy with direct RAS-targeted therapy (eg. degraders and\u002For inhibitors).\n* Any conditions that may affect the ability to take or absorb study drug.\n* Major surgery within 28 days prior to randomization.\n* Patient is unable or unwilling to comply with protocol-required study visits or procedures.","ALL","18 Years",{"count":786,"type":787},500,"ESTIMATED","INTERVENTIONAL",[790],"PHASE3","The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.",[793,794,795,796,797],"Pancreatic Cancer","PDAC","PDAC - Pancreatic Ductal Adenocarcinoma","Resectable Pancreatic Ductal Adenocarcinoma (PDAC)","Resected Pancreatic Adenocarcinoma",[793,794,799,800,801,802,803,804,805,806,807,797,808],"Pancreatic Ductal Adenocarcinoma","RAS","KRAS","NRAS","HRAS","RAS Wild-Type","RASolute","Resectable Pancreatic Ductal Adenocarcinoma","Resectable PDAC","RAS Mutation","2026-07-30",{"date":811,"type":812},"2026-07-31","ACTUAL",{"date":814,"type":812},"2025-12-15",{"date":816,"type":787},"2030-07-10",{"name":5,"class":6},60]