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For participants aged under 8 years who are capable of expressing assent, their assent shall be clearly documented.\n\nExclusion Criteria:\n\n* Subjects with closed epiphyses.\n* Patients with Turner syndrome carrying Y chromosome or Y-chromosome-derived fragments and without gonadectomy.\n* Other types of growth and development abnormalities, including but not limited to growth hormone deficiency (GHD), Noonan syndrome, Prader-Willi syndrome, and growth retardation caused by malnutrition.\n* Participation in any other clinical trial within 3 months prior to screening with pharmacological or non-pharmacological intervention received.\n* Inhaled glucocorticoids used continuously for more than 2 weeks, or oral\u002Fintravenous glucocorticoids used continuously for more than 1 week within 3 months prior to screening.\n* Receiving other treatments that may affect growth, including but not limited to methylphenidate, sex hormones, gonadotropin-releasing hormone analogs, aromatase inhibitors, anabolic agents, etc.\n* Abnormal liver and renal function at screening (ALT \\> 2 times the upper limit of normal; Cr \\> upper limit of normal).\n* Subjects with abnormal glucose metabolism, including: a. Diagnosed diabetes mellitus; b. Fasting blood glucose ≥ 6.1 mmol\u002FL on two consecutive measurements; c. Glycated hemoglobin (HbA1c) ≥ 6.5%; d. Impaired glucose tolerance judged by the investigator as unsuitable for participation in this study.\n* Presence of chronic infectious diseases judged by the investigator to interfere with study participation, such as chronic hepatitis B.\n* Subjects with systemic chronic diseases, such as chronic kidney disease, severe cardiovascular diseases (e.g., aortic dissection, uncontrolled hypertension), psychiatric and psychological disorders.\n* Subjects with severe congenital skeletal dysplasia; or those with scoliosis \\> 20°, significant kyphosis, claudication, or a prior diagnosis of slipped capital femoral epiphysis.\n* Subjects with a prior history of intracranial hypertension.\n* Subjects with a history of malignant tumor or current active malignant tumor, including intracranial tumors.\n* Known hypersensitivity to growth hormone or its excipients.\n* Subjects with celiac disease who have not maintained a gluten-free diet within 12 months prior to screening.\n* Any other conditions deemed inappropriate for enrollment in this clinical trial by the investigator.","FEMALE","2 Years","12 Years",{"count":582,"type":583},84,"ESTIMATED","INTERVENTIONAL",[586],"PHASE3","This is a multicenter, randomized, open-label, positive-controlled phase III confirmatory clinical study. A total of 84 children with short stature due to Turner Syndrome (TS) are planned to be enrolled. Stratified by age and karyotype, subjects will be randomized at a 1:1 ratio to either the test group or the positive control group with continuous treatment for 52 weeks. The study aims to compare the efficacy and safety of Inpegsomatropin-Injection versus Givopegsomatropin Solution Injection in children with TS-related short stature, so as to provide evidence for the new indication application of the investigational drug.",[589],"Turner Syndrome",[591,26],"Inpegsomatropin Injection","2026-07-21",{"date":594,"type":595},"2026-07-22","ACTUAL",{"date":597,"type":595},"2026-07-05",{"date":599,"type":583},"2030-02-28",{"name":5,"class":6},51]