[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647787":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":35,"centralContacts":36,"locations":42,"responsibleParty":58,"collaborators":35,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":35,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":35,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":84,"whyStopped":35,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"fractional carbon dioxide (CO₂) laser-assisted delivery of topical corticosteroids","EXPERIMENTAL","fractional carbon dioxide (CO₂) laser-assisted delivery of topical corticosteroids will be done on palmoplantar psoriasis every 4 weeks",[13],"Device: Fractional CO2 laser assisted drug delivery",{"label":15,"type":16,"description":17,"interventionNames":18},"Topical corticosteroids alone","ACTIVE_COMPARATOR","Application of topical corticosteroid alone in patients with palmoplantar psoriasis daily.",[19],"Drug: Topical Corticosteroid (TCS)",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Fractional CO2 laser assisted drug delivery","Sessions of fractional CO2 every 4 weeks with application of topical steroids",[9],[27],"fractional CO2 laser",{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"DRUG","Topical Corticosteroid (TCS)","Daily application of topical corticosteroids on palmoplantar psoriasis",[15],[34],"Topical steroids",null,[37],{"name":38,"role":39,"phone":40,"phoneExt":35,"email":41},"Amira M Elbendary, MD","CONTACT","+201555668584","aelbendary@kasralainy.edu.eg",[43],{"facility":5,"status":35,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Cairo","Cairo Governorate","11562","Egypt","EG",{"type":50,"coordinates":51},"Point",[52,53],31.24967,30.06263,{"lat":53,"lon":52},[56],{"name":57,"role":39,"phone":35,"phoneExt":35,"email":41},"Amira Elbendary, MD",{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","Amira Elbendary","Dr","100647787","phase-4-combined-fractional-co-laser-and-topical-corticosteroid-versus-topical-corticosteroid-only-in-the-treatment-of-palmoplantar-psoriasis-100647787",false,"NCT07713212","Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis","Comparative Study of the Efficacy and Safety of Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis: A Pilot Randomized Controlled Clinical Trial","Inclusion criteria\n\n* Adults aged ≥18 years\n* Stable psoriasis\n* Confirmed cases of palmoplantar psoriasis (with or without psoriasis elsewhere) dermoscopically(Hand \\_held dermoscopy) and histopathologically if required.\n* Willingness to comply with treatment and follow-up\n* Written informed consent obtained\n\nExclusion criteria:\n\n* Other palmoplantar dermatoses (eczema, tinea, keratoderma)\n* Generlized Pustular psoriasis\n* Erythrodermic psoriasis\n* Use of:\n\n  * Systemic antipsoriatic therapy within 3 months\n  * Biologic therapy within 12 weeks\n  * Topical treatment on palms\u002Fsoles within 2 weeks\n* Pregnancy or lactation\n* History of photosensitivity disorders","ALL","18 Years","60 Years",{"count":73,"type":74},32,"ESTIMATED","INTERVENTIONAL",[77],"PHASE4","To assess whether adding fractional laser to topical corticosteroid improves treatment outcomes in palmoplanter psoriasis compared to topical corticosteroid alone.",[80],"Psoriasis",[82,27,83],"psoriasis","topical treatment","NOT_YET_RECRUITING","2026-07-14",{"date":87,"type":88},"2026-07-20","ACTUAL",{"date":90,"type":74},"2026-08-15",{"date":92,"type":74},"2027-02-15",{"name":5,"class":6},1]