[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654530":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":22,"studyPopulation":11,"armGroups":23,"interventions":33,"overallOfficials":43,"centralContacts":48,"locations":54,"responsibleParty":73,"collaborators":11,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":11,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":11,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":11,"overallStatus":56,"whyStopped":11,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Pakistan Institute of Medical Sciences","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Emergence Delirium PAED score",null,"PAED score will be calculated upon arrival in Post Anesthesia care unit then at 5,10,15,30 minutes interval",{"allocation":14,"interventionModel":15,"interventionModelDescription":11,"primaryPurpose":16,"observationalModel":11,"timePerspective":11,"maskingInfo":17},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":18,"maskingDescription":11,"whoMasked":19},"DOUBLE",[20,21],"PARTICIPANT","OUTCOMES_ASSESSOR","A randomized clinical trial in which we will compare a single dose propofol with a single dose of dexmedetomodine given at the end of surgery after sevoflurane \\_based anesthesia to prevent post operative emergence agitation which is a group of behaviours consisting of confusion , disorientation,hyperactivity and even physical harm to themselves and others. this behavioural response is assessed by a score which is called peadriatric anesthesia emergence delerium scale (PEAD) which consist of 5-itms and 5-point scale ,ranging from not at all to extremely.the total score range from 0 to 20,with higher scores indicating more svere emergence agitation . In this study , the PEAD score will be recorded at 0,5,10,15,and 30 minutes after the child reach the recovery room ,and score greater than 10 at any of these readings will be taken as emergence agitation or delerium.",[24,29],{"label":25,"type":26,"description":11,"interventionNames":27},"Group propofol","ACTIVE_COMPARATOR",[28],"Drug: propofol 1mg\u002Fkg",{"label":30,"type":26,"description":11,"interventionNames":31},"group dexmedetomidine",[32],"Drug: Dexmedetomidine",[34,39],{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":11},"DRUG","propofol 1mg\u002Fkg","1mg\u002Fkg propofol given 10 minutes before the end of surgery",[25],{"type":35,"name":40,"description":41,"armGroupLabels":42,"otherNames":11},"Dexmedetomidine","0.3mcg\u002Fkg of dexmedetomidine to group D patients will be given after dilution with 10ml of 0.9%saline over 1 min given 10 minutes before extubation",[30],[44],{"name":45,"affiliation":46,"role":47},"Naheed Fatima","Head of Department","STUDY_CHAIR",[49],{"name":50,"role":51,"phone":52,"phoneExt":11,"email":53},"Muhammad Haroon Principal Investigator, MBBS, FCPS","CONTACT","+92-333-5236956","haroonanwar22@gmail.com",[55],{"facility":5,"status":56,"city":57,"state":58,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"RECRUITING","Islamabad","Federal","44000","Pakistan","PK",{"type":63,"coordinates":64},"Point",[65,66],73.04329,33.72148,{"lat":66,"lon":65},[69],{"name":70,"role":51,"phone":71,"phoneExt":11,"email":72},"Naheed Fatima, MBBS,FCPS","03005236655","naheedfk73@gmail.com",{"type":74,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Muhammad Haroon Anwar","Principal investigator","100654530","phase-4-comparing-the-efficacy-of-propofol-and-dexmedetomidine-in-prevention-of-emergence-agitation-after-sevoflurane-anesthesia-in-children-100654530",false,"NCT07799311","Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children","Comparison of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia Following Inguinal Hernia Repair: A Randomized Control Trial","Inclusion Criteria:\n\n1- age 2-12 years 2-elective inguinal hernia repair under general anesthesia\n\n\\-\n\nExclusion Criteria:\n\n1. congenital anomalies\n2. allergic to study medications\n3. chronic pain syndromes\n4. malnourishment -",true,"ALL","2 Years","12 Years",{"count":89,"type":90},114,"ESTIMATED","INTERVENTIONAL",[93],"PHASE4","This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will measure this by a special scale which is used to evaluate these behavioural changes.",[96],"Emergence Delirium, Anesthesia","2026-08-28",{"date":99,"type":100},"2026-09-02","ACTUAL",{"date":97,"type":100},{"date":103,"type":90},"2026-11-28",{"name":5,"class":6},1]