[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646931":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":41,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":25,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":66,"whyStopped":25,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":25},{"fullName":5,"class":6},"Beth Israel Deaconess Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High volume low concentration","ACTIVE_COMPARATOR","combination product: 0.0625% bupivacaine with 2 mcg fentanyl delivered in 12 ml bolused every 40 minutes",[13],"Drug: administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes",{"label":15,"type":16,"description":17,"interventionNames":18},"Low concentration high volume","EXPERIMENTAL","combination product: 0.125% bupivacaine with 4 mcg fentanyl delivered in 6 ml bolused every 40 minutes",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes","Dose of medication delivered using a programmed intermittent epidural bolus",[9,15],null,[27],{"name":28,"affiliation":5,"role":29},"Philip Hess, MD","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Elizabeth Amis","CONTACT","(617) 667-1861","eamis@bidmc.harvard.edu",{"type":29,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Phillip Hess","Principle investigator","100646931","phase-4-does-the-volume-of-medication-affect-the-success-of-labor-epidural-analgesia-100646931",false,"NCT07684365","Does the Volume of Medication Affect the Success of Labor Epidural Analgesia","Impact of Injected Volume on Programmed Intermittent Epidural Bolus Analgesia","EpiVol","Inclusion Criteria:\n\n* 18 years of age or older\n* Gestational age of 36 weeks or greater\n* American Society of Anesthesiology physical status 2\n* Induction of labor or early labor (cervical dilation \\\u003C 6cm)\n* Singleton gestation\n* Vertex presentation\n\nExclusion Criteria:\n\n* Preeclampsia\n* Receiving magnesium sulfate\n* Having received narcotics within 4 hours\n* Multiple gestation\n* Major fetal anomalies or demise\n* Previous spine surgery\n* Known major spine pathology\n* Substance use disorder","FEMALE","18 Years","50 Years",{"count":51,"type":52},70,"ESTIMATED","INTERVENTIONAL",[55],"PHASE4","The purpose of this study is to evaluate whether changing the volume and concentration of a medication affects the quality of pain relief and the side effects associated with labor epidural analgesia.",[58],"Labor Pain and to Reduce Pain",[60,61,62,63,64,65],"epidural analgesia","Obstetric anesthesia","bupivacaine","fentanyl","programmed intermittent epidural bolus","labor pain","NOT_YET_RECRUITING","2026-07-02",{"date":69,"type":70},"2026-07-06","ACTUAL",{"date":72,"type":52},"2026-08-15",{"date":74,"type":52},"2027-12-31",{"name":5,"class":6}]