[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569532":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":25,"eligibilityCriteria":45,"healthyVolunteers":42,"sex":46,"minAge":47,"maxAge":25,"enrollmentInfo":48,"targetDuration":25,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":61,"whyStopped":25,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":25},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Quadratus lumborum block (QLB group)","EXPERIMENTAL","patients will receive bilateral QLB with a 40-ml mixture of 20 ml of 0.5% levobupivacaine diluted with 20 ml of 0.9% N.S. (20 ml to be injected on each side).",[13],"Drug: Levobupivacaine",{"label":15,"type":10,"description":16,"interventionNames":17},"Rectus sheath block (RSB group)","patients will receive bilateral RSB with a 60 ml mixture of 1.5 mic\u002Fkg dexmedetomidine added to 30 ml of 0.5% levobupivacaine diluted with 30 ml of 0.9% N.S. (30 ml to be administered on each side, divided into 15 ml for the upper segment and 15 ml for the lower segment).",[18],"Drug: Levobupivacaine + Dexmedetomidine",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Levobupivacaine","40-ml mixture of 20 ml of 0.5% levobupivacaine diluted with 20 ml of 0.9% N.S. (20 ml to be injected on each side",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Levobupivacaine + Dexmedetomidine","60 ml mixture of 1.5 mic\u002Fkg dexmedetomidine added to 30 ml of 0.5% levobupivacaine diluted with 30 ml of 0.9% N.S. (30 ml to be administered on each side, divided into 15 ml for the upper segment and 15 ml for the lower segment).",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Kerollos Ibrahim Gayed Ibrahim, resident doctor","CONTACT","+201282351859","Cerles.16266305@med.aun.edu.eg",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Kerollos Ibrahim Gayed Ibrahim","resident doctor at Anaesthesia, I.C.U and pain management","100569532","phase-4-efficacy-and-safety-of-adding-dexmedetomidine-to-levobupivacaine-in-rectus-sheath-block-compared-to-quadratus-lumborum-block-in-patients-undergoing-lower-abdominal-cancer-surgery-a-randomized-clinical-trial-100569532",false,"NCT06695468","Efficacy and Safety of Adding Dexmedetomidine to Levobupivacaine in Rectus Sheath Block Compared to Quadratus Lumborum Block in Patients Undergoing Lower Abdominal Cancer Surgery: A Randomized Clinical Trial","Inclusion Criteria:\n\n1. Patients subjected to major lower abdominal cancer surgeries.\n2. The enrolled age will be from 18 years to 70 years\n3. ASA I-III and NYHA I-III.\n\nExclusion Criteria:\n\n1. ASA physical status \\>III and NYHA\\>III\n2. Patient refusal\n3. Body mass index \\>40 kg\u002Fm2\n4. Preoperative opioid consumption\n5. Infection at the incision site\n6. A history of hematological disorders or coagulation abnormality\n7. Previous abdominal surgeries, severe hepatic or renal impairment\n8. Pregnant women\n\n10- Hypersensitivity to any of used drugs","ALL","18 Years",{"count":49,"type":50},122,"ESTIMATED","INTERVENTIONAL",[53],"PHASE4","Surgical trauma activates numerous receptors leading to severe postoperative pain. Seventy to seventy-five percent of the pain is somatic, originating from the anterior abdominal wall, and it often persists for 72 hours after open surgery. The objective of this study is to compare the efficacy and safety of adding dexmedetomidine to Levobupivacaine in rectus sheath block with quadrates lumborum block in patients undergoing lower abdominal cancer surgeries.",[56],"Abdominal Cancer Surgery",[58,59,22,60],"Quadratus Lumborum Block","dexmedetomidine","Rectus sheath block","NOT_YET_RECRUITING","2024-11-17",{"date":64,"type":65},"2024-11-19","ACTUAL",{"date":67,"type":50},"2024-12-01",{"date":69,"type":50},"2027-01-01",{"name":5,"class":6}]