[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607587":3},{"organization":4,"outcomesModule":7,"designInfo":35,"detailedDescription":34,"studyPopulation":34,"armGroups":44,"interventions":57,"overallOfficials":34,"centralContacts":65,"locations":71,"responsibleParty":92,"collaborators":34,"id":96,"slug":97,"hasResults":98,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":98,"sex":104,"minAge":105,"maxAge":34,"enrollmentInfo":106,"targetDuration":34,"studyType":109,"phases":110,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":74,"whyStopped":34,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":126},{"fullName":5,"class":6},"University Tunis El Manar","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":34},[9],{"measure":10,"description":11,"timeFrame":12},"Incidence of postoperative nausea and vomiting (PONV) within 2 hours post-surgery","Occurrence of at least one episode of nausea or vomiting within the first 2 hours after surgery.","2 hours after surgery.",[14,18,22,26,30],{"measure":15,"description":16,"timeFrame":17},"Recurrence of PONV beyond 2 hours postoperatively","Proportion of participants who experienced at least one additional episode of nausea or vomiting occurring after the 2-hour postoperative time point.","From 2 hours to 24 hours after surgery.",{"measure":19,"description":20,"timeFrame":21},"Incidence of postoperative nausea and vomiting (PONV) within 24 hours post-surgery","Occurrence of at least one episode of nausea or vomiting within the first 24 hours after surgery.","24 hours after surgery.",{"measure":23,"description":24,"timeFrame":25},"Total number of vomiting episodes","Cumulative number of vomiting episodes recorded per participant during the first 24 hours after surgery.","Within 24 hours post-surgery.",{"measure":27,"description":28,"timeFrame":29},"Use of rescue antiemetics","The need for rescue antiemetics within 24 hours postoperatively.","24 hours postoperatively",{"measure":31,"description":32,"timeFrame":33},"Incidence of ginger-related adverse events","Number of participants experiencing adverse events known to be associated with ginger, including gastrointestinal discomfort (heartburn, abdominal pain, bloating, diarrhea), bleeding, or allergic reactions in the 24 hours after surgery.","Within 24 hours after surgery",null,{"allocation":36,"interventionModel":37,"interventionModelDescription":34,"primaryPurpose":38,"observationalModel":34,"timePerspective":34,"maskingInfo":39},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":40,"maskingDescription":34,"whoMasked":41},"DOUBLE",[42,43],"PARTICIPANT","INVESTIGATOR",[45,51],{"label":46,"type":47,"description":48,"interventionNames":49},"Ginger group","ACTIVE_COMPARATOR","Patients will receive 800 mg of oral ginger 2 hours before laparoscopic cholecystectomy",[50],"Drug: Ginger",{"label":52,"type":53,"description":54,"interventionNames":55},"Placebo group","PLACEBO_COMPARATOR","Patients will receive an oral placebo capsule identical in appearance to ginger, administered 2 hours before laparoscopic cholecystectomy",[56],"Drug: Placebo",[58,62],{"type":59,"name":60,"description":48,"armGroupLabels":61,"otherNames":34},"DRUG","Ginger",[46],{"type":59,"name":63,"description":54,"armGroupLabels":64,"otherNames":34},"Placebo",[52],[66],{"name":67,"role":68,"phone":69,"phoneExt":34,"email":70},"Ibtissem BEN TALEB, M.D.","CONTACT","+216 23 133 748","ibtissem.bentaleb@fmt.utm.tn",[72],{"facility":73,"status":74,"city":75,"state":76,"zip":77,"country":78,"countryCode":79,"cosmosGeoPoint":80,"geoPoint":85,"contacts":86},"Mohamed Taher Maamouri University Hospital","RECRUITING","Nabeul","Nabeul Governorate","8000","Tunisia","TN",{"type":81,"coordinates":82},"Point",[83,84],10.73763,36.45606,{"lat":84,"lon":83},[87,88],{"name":67,"role":68,"phone":69,"phoneExt":34,"email":70},{"name":89,"role":68,"phone":90,"phoneExt":34,"email":91},"Mechaal BEN ALI, M.D.","+216 98 657 034","mechaal_benali@yahoo.fr",{"type":93,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","Ben Taleb Ibtissem","Assistant Professor in Anesthesiology and Intensive Care","100607587","phase-4-ginger-to-prevent-nausea-and-vomiting-after-laparoscopic-cholecystectomy-100607587",false,"NCT07190495","Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy","Preoperative Ginger for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Double-Blind Randomized Controlled Trial","GINGER-PONV","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Able to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to ginger\n* Documented history of bleeding disorders or current treatment with anticoagulant agents\n* History of severe postoperative nausea and vomiting or an Apfel score of 4\n* Administration of antiemetic drugs or corticosteroids during the preoperative period\n* Pregnancy or breastfeeding\n* Active gastrointestinal or liver disease","ALL","18 Years",{"count":107,"type":108},102,"ESTIMATED","INTERVENTIONAL",[111],"PHASE4","This study aims to evaluate whether preoperative oral administration of ginger (800 mg, given 2 hours before surgery) reduces the incidence and severity of postoperative nausea and vomiting (PONV) within the first 24 hours after laparoscopic cholecystectomy.",[114,115],"Postoperative Nausea and Vomiting","Laparoscopic Cholecystectomy",[60,114,115],"2026-04-27",{"date":119,"type":120},"2026-04-28","ACTUAL",{"date":122,"type":120},"2025-07-05",{"date":124,"type":108},"2026-12",{"name":5,"class":6},1]