[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549078":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":37,"studyPopulation":26,"armGroups":38,"interventions":58,"overallOfficials":26,"centralContacts":97,"locations":106,"responsibleParty":881,"collaborators":883,"id":887,"slug":888,"hasResults":889,"nctId":890,"briefTitle":891,"officialTitle":892,"acronym":893,"eligibilityCriteria":894,"healthyVolunteers":889,"sex":895,"minAge":896,"maxAge":26,"enrollmentInfo":897,"targetDuration":26,"studyType":900,"phases":901,"briefSummary":903,"conditions":904,"keywords":910,"overallStatus":109,"whyStopped":26,"lastUpdateSubmitDate":921,"lastUpdatePostDateStruct":922,"startDateStruct":925,"completionDateStruct":927,"leadSponsor":929,"locationsCount":930},{"fullName":5,"class":6},"Region Skane","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":26},[9],{"measure":10,"description":11,"timeFrame":12},"Evaluation of functional outcome based on the Utility Weighted modified Rankin Scale score","The modified Rankin Scale (mRS) is an efficient, reliable, and simple functional outcome measure widely used as a primary endpoint in clinical trials for acute stroke. However, being an ordered categorical scale, it may not reflect potentially unequal differences in perceived quality of life associated with certain 1-point shifts vs others. Utility-weighted mRS is a score that weighs the mRS against a health utility scale, which defined as the desirability of a specific health outcome, facilitates comparisons of health-related quality of life across an array of clinical settings. Utility weights, as referred to hereafter, reflect the spectrum between perfect health (a score of 1) and outcomes worse than death (where death is a score of 0 and negative values indicate an outcome worse than death). The primary outcome is UW-mRS at 3 months and will be analyzed by means of a linear regression, with mRS as a dependent variable with 7 levels (0 \\[no residual symptom\\] to 6 \\[death\\]).","180±30 days",[14,18,21,24],{"measure":15,"description":16,"timeFrame":17},"Ordinal shift analysis of mRS","The assessment of shifts in the distribution of mRS scores through the evaluation of scores in ordinal groups","180 days±30 days",{"measure":19,"description":20,"timeFrame":17},"Assessment of health-related quality of life (HRQoL)","This will be assessed using the EuroQoL Group 5-Dimension self-report questionnaire (EQ-5D). The VAS is a scale from 0 (worst imaginable health state) to 100 (best imaginable health state).",{"measure":22,"description":23,"timeFrame":17},"Poor outcome defined as mRS 3-6","Binary secondary outcomes will be analyzed by means of standard GEE or random-effects regression with a logistic link and\u002For time-to-event type endpoints using the Cox model with a sandwich formula or a frailty model.",{"measure":25,"description":23,"timeFrame":17},"Separate outcomes for death and disability",null,{"allocation":28,"interventionModel":29,"interventionModelDescription":30,"primaryPurpose":31,"observationalModel":26,"timePerspective":26,"maskingInfo":32},"RANDOMIZED","PARALLEL","international multicentre, batched, cluster. Patients are not randomized, hospitals will be randomized.\n\nIn each batch, hospitals are randomized into two groups according to the timing of the intervention (Care Bundle) over 3 phases (usual care, randomized evaluation, post-implementation follow-up):\n\nPhase 1 - baseline routine data collection, training and formative study (assess context and local resources, support adjustment of the protocol into local pathways) Phase 2 - start intervention implementation in the intervention group, data collection for comparison with usual care in the control group Phase 3 - all hospitals implement the intervention, data collection for quality improvement, assess sustainability and integration","TREATMENT",{"masking":33,"maskingDescription":34,"whoMasked":35},"SINGLE","Treatment allocation is on a site-level and not on an individual level. The allocation is not blinded. Follow-up clinical outcome assessors, who have no prior association with the study and are unaware of the patients' allocation to either the intervention or control arm, will contact the participant by telephone at 6 months. At the initiation of contact, study subjects will be urged not to disclose their treatment allocation.",[36],"OUTCOMES_ASSESSOR","Spontaneous intracerebral hemorrhage (ICH) accounts for 10 to 15% of all strokes in high-income countries (HIC), and nearly twice this number in low-income to upper-middle-income countries (LMIC) (29.5%). It is the most devastating type of stroke given the high one-month case fatality of approximately 30-40%, and only 12-39% suffer persistent disability.\n\nDespite several advances in the management of acute ischemic stroke supported by numerous randomized controlled trials (RCT), progress in establishing novel interventions to improve outcomes for ICH has been slow. Still today, the diagnosis of ICH evokes pessimism among treating physicians, and patients may be withheld guideline adherent treatment for this reason. This nihilistic approach is presumably due to an over-estimation of poor outcome, often influenced by the neurologically devastating features commonly present at ICH admission. Additionally, the scarcity of RCTs providing strong evidence for treatment recommendations may contribute to a more reluctant approach in the acute setting of ICH, particularly when presenting with debilitating symptoms.\n\nThe third INTEnsive care bundle with BP reduction in acute cerebral hemorrhage trial (INTERACT3) was recently published in 2023. This trial employed a stepped wedge cluster RCT design to evaluate the implementation of a Care Bundle protocol. This comprehensive protocol included early intensive BP lowering (EIBPL), management of pyrexia and hyperglycemia, and the early reversal of OAC treatment. The design of this trial drew inspiration from a post-hoc analysis of the INTERACT2 study that showed that the scoring of abnormal baseline variables, interventions included in the future INTERACT3 Care Bundle, independently predicted a poor functional outcome following ICH. The implementation of the time sensitive bundle of care in INTERACT3 resulted in an improved functional outcome at 6 months following ICH. However, as the trial included patients predominantly from LMIC, further studies are warranted to determine if these results are applicable to HIC with a more applicable Care Bundle for these populations. An earlier intervention study from the United Kingdom, published in 2019, studied a similar 'quality improvement' acute Care Bundle. This Care Bundle aimed to improve the speed of treatment delivery, access to acute care, and decrease case fatality following ICH. Despite certain limitations, including a non-randomized design, this study demonstrated significantly lower mortality rates in patients receiving the Care Bundle versus the pre-implementation standard of care.\n\nI-CATCHER is an international, multicenter, batched, parallel, cluster, randomized clinical trial (RCT) to assess a multifaceted package of protocols in a broad range of patients with acute ICH. In each batch, hospitals will be randomized into two groups according to the timing of the intervention (Care Bundle) over 3 phases (phase 1: usual care, phase 2: randomized evaluation - to intervention or usual care, phase 3: post-implementation follow-up - all hospitals implement the intervention). This design will capture consecutive patients with ICH and allow continued intervention in perpetuity as more hospitals join. Compared to a conventional stepped-wedge cluster RCT, the intervention effect in this design is less likely to be confounded by background temporal trends as only baseline and parallel comparison data (first 2 periods in bold black frame) are used to determine the effectiveness of the Care Bundle. All hospitals will be exposed to the Care Bundle which allows assessment of sustainability and integration of the intervention into routine practice. Each batch period is 18 months (6 months per phase); whole study will be rolled out in 2.5 years.\n\nThis design involves implementation of an intervention package applied to all patients with ICH as part of routine care. Patients are only excluded if they refuse to have details of their management included and\u002For participate in follow-up procedures.\n\nStudy site inclusion criteria: Organized systems of acute stroke care; no established comprehensive protocols for the management of ICH; suitable location, infrastructure and willingness to participate in clinical research; suitable numbers of ICH patients (at least 30 per year).\n\nPatient inclusion criteria: Adults (≥18 years) with spontaneous ICH confirmed by imaging and admitted hospital within 24 hours of the onset of symptoms.",[39,52],{"label":40,"type":41,"description":42,"interventionNames":43},"Intervention group","ACTIVE_COMPARATOR","A range of implementation methods will be used to introduce an active Care Bundle with time- and target-based metrics that involve the rapid correction of abnormal physiological variables over days or hospital discharge (or death, if sooner) and referral pathways",[44,45,46,47,48,49,50,51],"Other: Reversal of Oral anticoagulation within 30 minutes","Other: Early intensive blood pressure lowering","Other: Treatment of pyrexia","Other: Hyperglycemia treatment","Other: Do-not-resuscitate (DNR) or withdrawal of care","Other: Referral to Intensive Care","Other: Referral to Neurosurgery","Diagnostic Test: Repeat brain imaging",{"label":53,"type":54,"description":55,"interventionNames":56},"Usual care","PLACEBO_COMPARATOR","For patients in the usual-care group, decisions about the location of care delivery, investigations, monitoring, and all treatments are made by the treating clinical team. Data will be collected regarding the management of patients, including insertion of invasive monitoring devices, intravenous fluid resuscitation, BP lowering, vasoactive support, glycemic control, mechanical ventilation, neurosurgery, and other supportive therapy.",[57],"Other: Standard care",[59,65,69,73,77,81,85,89,94],{"type":6,"name":60,"description":61,"armGroupLabels":62,"otherNames":63},"Reversal of Oral anticoagulation within 30 minutes","In situations of either an elevated INR with the use of warfarin - treatment with either 3- or 4-factor prothrombin complex concentrate (PCC) or fresh frozen plasma (FFP) within 30 minutes of ICH diagnosis on NCCT to reach and maintain an INR target \\\u003C1.3; or where there has been recent use (\\\u003C48 hours) of a direct oral anticoagulant (DOAC), use of an appropriate reversal agent within 30 minutes, where available, and according to local approvals.",[40],[64],"OAC reversal",{"type":6,"name":66,"description":67,"armGroupLabels":68,"otherNames":26},"Early intensive blood pressure lowering","A systolic blood pressure (BP) target of 130-140 mmHg within 30 minutes of ICH diagnosis on NCCT is strived for, and to maintain this BP level for the first 7 days (for patients presenting with blood pressure \\\u003C200 mmHg). If blood pressure ≥200 and \\\u003C220, a target BP of 160 mmHg should be targeted at 30 minutes, and 130-140 mmHg should be achieved in 60 minutes. If BP ≥220, target BP of 160 mmHg and should be achieved in 60 minutes.",[40],{"type":6,"name":70,"description":71,"armGroupLabels":72,"otherNames":26},"Treatment of pyrexia","To achieve a body temperature target \\\u003C37.5 °C within the first 24h following ICH diagnosis on NCCT",[40],{"type":6,"name":74,"description":75,"armGroupLabels":76,"otherNames":26},"Hyperglycemia treatment","To maintain a blood glucose level 7-10 mmol\u002FL within the first 24h following ICH diagnosis on NCCT",[40],{"type":6,"name":78,"description":79,"armGroupLabels":80,"otherNames":26},"Do-not-resuscitate (DNR) or withdrawal of care","Refrain from the use of DNR or withdrawal of care orders for 48 hours",[40],{"type":6,"name":82,"description":83,"armGroupLabels":84,"otherNames":26},"Referral to Intensive Care","Immediate (\\\u003C30 min) referral to intensive care if airway, breathing and\u002For circulation are compromized",[40],{"type":6,"name":86,"description":87,"armGroupLabels":88,"otherNames":26},"Referral to Neurosurgery","Immediate (\\\u003C30 min) referral to neurosurgery if any of the following criteria are fulfilled:\n\n* Large and\u002For rapidly evolving supratentorial ICH (\\>20 ml volume)\n* Any intraventricular extension\n* Posterior fossa bleed, irrespective of volume\n* Suspicion of a vascular malformation, independent of volume or location\n* Reduction in reaction to sensory stimulation or drowsiness",[40],{"type":90,"name":91,"description":92,"armGroupLabels":93,"otherNames":26},"DIAGNOSTIC_TEST","Repeat brain imaging","Repeat 6-12-hour brain imaging with the physicians choice of modality, preferably computed tomography (CT), if clinical deterioration or the patient received OAC reversal treatment",[40],{"type":6,"name":95,"description":55,"armGroupLabels":96,"otherNames":26},"Standard care",[53],[98,103],{"name":99,"role":100,"phone":101,"phoneExt":26,"email":102},"Teresa Ullberg, MD, PhD","CONTACT","0046175057","i-catcher@med.lu.se",{"name":104,"role":100,"phone":26,"phoneExt":26,"email":105},"Trine Apostolaki-Hansson, MD PhD","trine.apostolaki-hansson@med.lu.se",[107,126,142,156,173,191,206,220,234,249,267,283,296,313,327,343,357,373,387,397,412,427,440,454,468,482,494,508,522,539,553,567,581,596,608,623,637,650,664,679,693,707,718,727,738,753,767,784,798,809,823,840,853,866],{"facility":108,"status":109,"city":110,"state":111,"zip":112,"country":113,"countryCode":114,"cosmosGeoPoint":115,"geoPoint":120,"contacts":121},"The University of Oklahoma Health","RECRUITING","Oklahoma City","Oklahoma","73126-0901","United States","US",{"type":116,"coordinates":117},"Point",[118,119],-97.51643,35.46756,{"lat":119,"lon":118},[122],{"name":123,"role":100,"phone":124,"phoneExt":26,"email":125},"Faddi G. Saleh Velez, MD","405-271-4113","Faddi-SalehVelez@ou.edu",{"facility":127,"status":109,"city":128,"state":26,"zip":129,"country":130,"countryCode":131,"cosmosGeoPoint":132,"geoPoint":136,"contacts":137},"Royal Adelaide Hospital","Adelaide","5000","Australia","AU",{"type":116,"coordinates":133},[134,135],138.59863,-34.92866,{"lat":135,"lon":134},[138],{"name":139,"role":100,"phone":140,"phoneExt":26,"email":141},"Timothy Kleinig, Prof","+61 8 7074 2903","Timothy.Kleinig@sa.gov.au",{"facility":143,"status":109,"city":144,"state":26,"zip":145,"country":130,"countryCode":131,"cosmosGeoPoint":146,"geoPoint":150,"contacts":151},"Monash Medical Centre","Clayton","3168",{"type":116,"coordinates":147},[148,149],145.11667,-37.91667,{"lat":149,"lon":148},[152],{"name":153,"role":100,"phone":154,"phoneExt":26,"email":155},"Henry Ma, Prof","+61 3 8572 2131","Henry.Ma@monashhealth.org",{"facility":157,"status":158,"city":159,"state":26,"zip":160,"country":130,"countryCode":131,"cosmosGeoPoint":161,"geoPoint":165,"contacts":166},"The George Institute for Global Health","NOT_YET_RECRUITING","Sydney","NSW 2000",{"type":116,"coordinates":162},[163,164],151.20732,-33.86785,{"lat":164,"lon":163},[167,171],{"name":168,"role":100,"phone":169,"phoneExt":26,"email":170},"Menglu Ouyang, PhD, MPH","0061280524808","mouyang@georgeinstitute.org.au",{"name":168,"role":172,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"facility":174,"status":109,"city":175,"state":176,"zip":177,"country":178,"countryCode":179,"cosmosGeoPoint":180,"geoPoint":184,"contacts":185},"Health Sciences North\u002FHealth Sciences North Research Institute","Greater Sudbury","Ontario","P3E 5J1","Canada","CA",{"type":116,"coordinates":181},[182,183],-80.99001,46.49,{"lat":183,"lon":182},[186],{"name":187,"role":100,"phone":188,"phoneExt":189,"email":190},"Ravinder Singh, MD","705-523-7300","1932","ravsingh@hsnsudbury.ca",{"facility":192,"status":109,"city":193,"state":176,"zip":194,"country":178,"countryCode":179,"cosmosGeoPoint":195,"geoPoint":199,"contacts":200},"Hamilton General Hospital","Hamilton","L8L 2X2",{"type":116,"coordinates":196},[197,198],-79.84963,43.25011,{"lat":198,"lon":197},[201],{"name":202,"role":100,"phone":203,"phoneExt":204,"email":205},"Aristeidis Katsanos, MD, PhD","905-521-2100","44132","Aristeidis.Katsanos@phri.ca",{"facility":207,"status":109,"city":208,"state":176,"zip":209,"country":178,"countryCode":179,"cosmosGeoPoint":210,"geoPoint":214,"contacts":215},"Ottawa Hospital Research Institute","Ottawa","K1Y 4E9",{"type":116,"coordinates":211},[212,213],-75.69812,45.41117,{"lat":213,"lon":212},[216],{"name":217,"role":100,"phone":218,"phoneExt":26,"email":219},"Dar Dowlatshahi, MD PhD FRCPC","+1 613-761-4709","ddowlat@toh.ca",{"facility":221,"status":109,"city":222,"state":26,"zip":26,"country":222,"countryCode":223,"cosmosGeoPoint":224,"geoPoint":228,"contacts":229},"Hong Kong University Hospital","Hong Kong","HK",{"type":116,"coordinates":225},[226,227],114.17469,22.27832,{"lat":227,"lon":226},[230],{"name":231,"role":100,"phone":232,"phoneExt":26,"email":233},"Kay Cheong Teo, MD","(+852) 2255 3749","kcteo@hku.hk",{"facility":235,"status":109,"city":236,"state":26,"zip":237,"country":238,"countryCode":239,"cosmosGeoPoint":240,"geoPoint":244,"contacts":245},"Landspitali University Hospital","Reykjavik","105","Iceland","IS",{"type":116,"coordinates":241},[242,243],-21.89541,64.13548,{"lat":243,"lon":242},[246],{"name":247,"role":100,"phone":248,"phoneExt":26,"email":26},"Björn Logi Þórarinsson, MD MSc FESO","+354 8253850",{"facility":250,"status":109,"city":251,"state":26,"zip":252,"country":253,"countryCode":254,"cosmosGeoPoint":255,"geoPoint":259,"contacts":260},"Avezzano Ospedale SS. Filippo e Nicola","Avezzano","67051","Italy","IT",{"type":116,"coordinates":256},[257,258],13.42641,42.02896,{"lat":258,"lon":257},[261,265],{"name":262,"role":100,"phone":263,"phoneExt":26,"email":264},"Simona Sacco, MD","+39 0863 4991","simona.sacco@univaq.it",{"name":266,"role":172,"phone":26,"phoneExt":26,"email":26},"Raffaele Ornello, MD",{"facility":268,"status":109,"city":269,"state":26,"zip":270,"country":253,"countryCode":254,"cosmosGeoPoint":271,"geoPoint":275,"contacts":276},"Citta di Castello Ospedale Città di Castello","Città di Castello","06012",{"type":116,"coordinates":272},[273,274],12.2375,43.46556,{"lat":274,"lon":273},[277,281],{"name":278,"role":100,"phone":279,"phoneExt":26,"email":280},"Silvia Cenciarelli, MD","+39 075 8932278","silvia.cenciarelli@uslumbria1.it",{"name":26,"role":100,"phone":282,"phoneExt":26,"email":26},"+39 075 9270801",{"facility":284,"status":109,"city":285,"state":26,"zip":253,"country":253,"countryCode":254,"cosmosGeoPoint":286,"geoPoint":290,"contacts":291},"Gubbio Ospedale di Gubbio e Gualdo Tadino","Gubbio",{"type":116,"coordinates":287},[288,289],12.57309,43.34996,{"lat":289,"lon":288},[292],{"name":293,"role":100,"phone":294,"phoneExt":26,"email":295},"Tatiana Mazzoli, MD","+39 075 5411","tatiana.mazzoli@uslumbria1.it",{"facility":297,"status":109,"city":298,"state":26,"zip":299,"country":253,"countryCode":254,"cosmosGeoPoint":300,"geoPoint":304,"contacts":305},"Azienda Ospedaliera Santa Maria della Misericordia Perugia","Perugia","06129",{"type":116,"coordinates":301},[302,303],12.38878,43.1122,{"lat":303,"lon":302},[306,310],{"name":307,"role":100,"phone":308,"phoneExt":26,"email":309},"Alessandro Bufi, MD","+39 075 5782266","alessandro.bufi147@gmail.com",{"name":311,"role":312,"phone":26,"phoneExt":26,"email":26},"Valeria Caso","SUB_INVESTIGATOR",{"facility":314,"status":109,"city":315,"state":26,"zip":316,"country":253,"countryCode":254,"cosmosGeoPoint":317,"geoPoint":321,"contacts":322},"Roma Policlinico Gemelli","Roma","00136",{"type":116,"coordinates":318},[319,320],11.10642,44.99364,{"lat":320,"lon":319},[323],{"name":324,"role":100,"phone":325,"phoneExt":26,"email":326},"Giovanni Frisullo, MD","+39 06 30151","Giovanni.frisullo@policlinicogemelli.it",{"facility":328,"status":109,"city":329,"state":26,"zip":330,"country":331,"countryCode":332,"cosmosGeoPoint":333,"geoPoint":337,"contacts":338},"National University of Malaysia Hospital","Kuala Lumpur","56000","Malaysia","MY",{"type":116,"coordinates":334},[335,336],101.68653,3.1412,{"lat":336,"lon":335},[339],{"name":340,"role":100,"phone":341,"phoneExt":26,"email":342},"Zhe Kang Law, MD MRCP FRCP PhD","+601126384288","zhe.kanglaw@hctm.ukm.edu.my",{"facility":344,"status":109,"city":345,"state":26,"zip":346,"country":331,"countryCode":332,"cosmosGeoPoint":347,"geoPoint":351,"contacts":352},"Universiti Putra Malaysia Hospital","Serdang","43400",{"type":116,"coordinates":348},[349,350],100.62476,5.20372,{"lat":350,"lon":349},[353],{"name":354,"role":100,"phone":355,"phoneExt":26,"email":356},"Abdul Hanif Khan Bin Yusof Khan, MD","+60192671685","ahanifkhan@upm.edu.my",{"facility":358,"status":109,"city":359,"state":26,"zip":360,"country":361,"countryCode":362,"cosmosGeoPoint":363,"geoPoint":367,"contacts":368},"Höglandssjukhuset i Eksjö","Eksjö","575 81","Sweden","SE",{"type":116,"coordinates":364},[365,366],14.97205,57.66643,{"lat":366,"lon":365},[369],{"name":370,"role":100,"phone":371,"phoneExt":26,"email":372},"Melania Vass","46102410000","melania.vass@rjl.se",{"facility":374,"status":109,"city":375,"state":26,"zip":376,"country":361,"countryCode":362,"cosmosGeoPoint":377,"geoPoint":381,"contacts":382},"Sahlgrenska Universitetssjukhuset","Gothenburg","413 45",{"type":116,"coordinates":378},[379,380],11.96679,57.70716,{"lat":380,"lon":379},[383],{"name":384,"role":100,"phone":385,"phoneExt":26,"email":386},"Petra Redfors, MD","46313421000","petra.redfors@vgregion.se",{"facility":388,"status":109,"city":375,"state":26,"zip":389,"country":361,"countryCode":362,"cosmosGeoPoint":390,"geoPoint":392,"contacts":393},"Östra Sjukhuset","41685",{"type":116,"coordinates":391},[379,380],{"lat":380,"lon":379},[394],{"name":395,"role":100,"phone":385,"phoneExt":26,"email":396},"Christina Heden Ståhl","christina.heden-stahl@vgregion.se",{"facility":398,"status":109,"city":399,"state":26,"zip":26,"country":361,"countryCode":362,"cosmosGeoPoint":400,"geoPoint":404,"contacts":405},"Hässleholms Sjukhus","Hässleholm",{"type":116,"coordinates":401},[402,403],13.76638,56.15905,{"lat":403,"lon":402},[406,410],{"name":407,"role":100,"phone":408,"phoneExt":26,"email":409},"Annika Nilsson","+451-29 63 30","Annika.AC.Nilsson@skane.se",{"name":411,"role":172,"phone":26,"phoneExt":26,"email":26},"Magnus Esbjörnsson, MD",{"facility":413,"status":109,"city":414,"state":26,"zip":26,"country":361,"countryCode":362,"cosmosGeoPoint":415,"geoPoint":419,"contacts":420},"Helsingborgs Lasarett","Helsingborg",{"type":116,"coordinates":416},[417,418],12.69437,56.04673,{"lat":418,"lon":417},[421,425],{"name":422,"role":100,"phone":423,"phoneExt":26,"email":424},"Angela Persson","+424061895","angela.persson@skane.se",{"name":426,"role":172,"phone":26,"phoneExt":26,"email":26},"Gustaf Westerberg, MD",{"facility":428,"status":109,"city":429,"state":26,"zip":26,"country":361,"countryCode":362,"cosmosGeoPoint":430,"geoPoint":434,"contacts":435},"Karolinska Universitetssjukhuset Huddinge","Huddinge",{"type":116,"coordinates":431},[432,433],17.98192,59.23705,{"lat":433,"lon":432},[436],{"name":437,"role":100,"phone":438,"phoneExt":26,"email":439},"Michael Mazya, MD","4612380000","michael.mazya@regionstockholm.se",{"facility":441,"status":109,"city":442,"state":26,"zip":443,"country":361,"countryCode":362,"cosmosGeoPoint":444,"geoPoint":448,"contacts":449},"Länssjukhuset Ryhov","Jönköping","551 85",{"type":116,"coordinates":445},[446,447],14.15618,57.78145,{"lat":447,"lon":446},[450],{"name":451,"role":100,"phone":452,"phoneExt":26,"email":453},"Veronica Gajdos","46102422870","veronika.gajdos@rjl.se",{"facility":455,"status":109,"city":456,"state":26,"zip":457,"country":361,"countryCode":362,"cosmosGeoPoint":458,"geoPoint":462,"contacts":463},"Länssjukhuset Kalmar","Kalmar","391 85",{"type":116,"coordinates":459},[460,461],16.36163,56.66157,{"lat":461,"lon":460},[464],{"name":465,"role":100,"phone":466,"phoneExt":26,"email":467},"Åsa Landerholm, 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